Sinusoidal Channels Research Articles

L1CAM and laminin vascular network: Association with the high-risk replacement histopathologic growth pattern in uveal melanoma liver metastases

AbstractThe replacement histopathologic growth pattern (rHGP) in melanoma liver metastases connotes an aggressive phenotype (vascular co-option; angiotropic extravascular migratory spread) and adverse prognosis. Herein, replacement and desmoplastic HGP (dHGP) were studied in uveal melanoma liver metastases (MUM). In particular, L1CAM and a “laminin vascular network” were detected at the advancing front of 14/20 cases (p = 0.014) and 16/20 cases (p = 6.4e–05) rHGPs, respectively, but both were absent in the dHGP (8/8 cases) (p = 0.014, and p = 6.3e–05, respectively). L1CAM highlighted progressive extension of angiotropic melanoma cells along sinusoidal vessels in a pericytic location (pericytic mimicry) into the hepatic parenchyma. An inverse relationship between L1CAM expression and melanin index (p = 0.012) suggested differentiation toward an amelanotic embryonic migratory phenotype in rHGP. Laminin labeled the basement membrane zone interposed between sinusoidal vascular channels and angiotropic melanoma cells at the advancing front. Other new findings: any percentage of rHGP and pure rHGP had a significant adverse effect on metastasis-specific overall survival (p = 0.038; p = 0.0064), as well as predominant rHGP (p = 0.0058). Pure rHGP also was associated with diminished metastasis-free survival relative to dHGP (p = 0.040), possibly having important implications for mechanisms of tumor spread. In conclusion, we report for the first time that L1CAM and a laminin vascular network are directly involved in this high-risk replacement phenotype. Further, this study provides more detailed information about the adverse prognostic effect of the rHGP in MUM.

Synthesis and Acidity Study of Na-ZSM-5 Zeolite

Zeolites are a special class of structured aluminosilicates with a developed inner surface and a large number of micropores, which allows them to be used as sorbents, membrane materials, and catalysts. Zeolite ZSM-5 is an aluminosilicate formed by parallel channels with a diameter of 5.3–5.6Å interconnected by sinusoidal channels with a diameter of 5.1–5.5Å. At the same time, the presence of aluminum atoms in the zeolite crystal lattice makes it possible to carry out dehydrogenation, esterification, isomerization, and aromatization reactions, and the presence of microchannels significantly increases the number of collisions of reacting compounds, which leads to a significant increase in the rate of chemical transformations in such systems. The synthesis of ZSM-5 zeolite using structure-directing agents has been known since the late 70s of the last centuries, while the high cost of structure-directing agents used and the long duration of hydrothermal synthesis and the need for subsequent post-synthetic procedures lead to a high cost of the resulting zeolite. One of the possible ways to reduce the cost of the synthesis of ZSM-5 zeolite is the direct use of ZSM-5 zeolite as a structure-forming agent, while the synthesis conditions play a decisive role in the structure of the resulting zeolite. The article presents the results of a study of the synthesis of ZSM-5 zeolite and a study of its acidic properties using locally produced reagents. Zeolite was prepared using pre-milled silica gel, sodium hydroxide, and sodium aluminate. The pre-weighed silica gel sample was filled with sodium hydroxide solution and stirred at 70 ℃ to form a colloidal solution, after which the pre-prepared sodium aluminate solution was added, and hydrothermal synthesis was carried out at 180 ℃ for 24 hours. During the synthesis, the Si/Al ratio was varied in the range from 7.5 to 2000, while the resulting acidity ranged from 0.002 to 0.265 mmol(NH3)/g(ZSM-5). It was found that the synthesis of ZSM-5 using pre-prepared reagent solutions is superior to the method using direct dissolution of solid reagents in an autoclave. An increase in the Si/Al ratio from 7.5 to 100 leads to a corresponding increase in surface acidity from 0.066 mmol(NH3)/g(ZSM-5) to 0.265 mmol(NH3)/g(ZSM-5). A further increase in the Si/Al ratio to 2000 leads to a decrease in surface acidity to 0.002–0.005 mmol(NH3)/g(ZSM-5). A reliable and simple method for the synthesis of ZSM-5 zeolite has been developed, providing a zeolite yield of up to 97%.

A novel opposite sinusoidal wave flow channel for performance enhancement of proton exchange membrane fuel cell

The optimized design of the flow field structure helps to enhance the mass transfer and water removal capacity of the proton exchange membrane fuel cell (PEMFC). A novel opposite sinusoidal wave flow channel is proposed in this study, and the influence of amplitudes and periods of the sinusoidal function on performance of PEMFC is explored by numerical simulation. The research results show that the mass transfer capacity of the opposite sinusoidal wave channel is better than that of the straight channel. By increasing the amplitude, combined with decreasing the period, the mass transfer capacity and the performance of the PEMFC can be effectively enhanced. Compared with the straight channel, for an amplitude of 0.8 mm and a period of 0.5Π mm at 2.0 A cm−2, the net power density is increased by 16.61% and 12.01% respectively. Moreover, based on the volume of fluid model, the transport process and distribution characteristics of liquid water in the straight channel and the opposite sinusoidal wave channel are compared and analyzed. The results show the drainage period of the opposite sinusoidal wave channel is half shorter compared to the straight channel. Therefore, the proposed opposite sinusoidal wave channel has better water removal capacity.

Effect of different frameworks on the zeolite catalyzed alkylation of benzene with 1-dodecene

Structure-reactivity relationship acts as a hot topic in the zeolite catalyzed reactions for a long time. Herein, Beta and MCM-49 with two representative frameworks are selected to elucidate this concept, attempting to reveal the essential difference in their catalytic performance for the alkylation of benzene with 1-dodecene from both experimental and theoretical aspects. It is revealed that the effective acid sites for the alkylation of benzene with 1-dodecene over MCM-49 are mainly located at the 12 MR (membered-ring) cups, wherein the reactants and products can diffuse with less restriction. Therefore, MCM-49 exhibits higher lifetime and selectivity although the 12 MR supercage and 10 MR sinusoidal channels possessing shape-selectivity contribute little to this reaction, which has also been further evidenced by the density functional theory (DFT) calculation results. The low lifetime and selectivity observed over Beta are mainly assigned to the strong accommodation and slow diffusion of reactants and products within its long channels, and decreasing crystal size or constructing hierarchical framework have been further demonstrated to be effective to alleviate its deactivation.

Introducing mesopore and regulating Al distribution for improving catalytic performances of ZSM-5 in furfuryl alcohol to levulinic acid

Catalytic valorization of biomass into chemicals and fuels plays a key role in order to achieve net-zero greenhouse gas emissions. Herein, a series of hierarchical ZSM-5 zeolites were synthesized by the post-treatment method to transform furfural alcohol (FAL) to levulinic acid (LA). ZSM-5 obtained from tandem alkaline treatment (0.2 M NaOH) and acid washing (0.1 M HCl), denoted as ZSM-5-OH0.2-H, exhibited the highest activity, affording 76.2% LA yield in 9:1 acetone–water mixed solvents at 393 K for 0.5 h. The enhanced adsorption capacity and acid accessibility of FAL on zeolite mediated by the introduction of mesopores, as well as the reduced secondary reactions of the generated LA due to few Al atoms in straight and sinusoidal channels (as confirmed by UV–vis diffuse reflectance), were responsible for the outstanding catalytic performance of ZSM-5-OH0.2-H. The structure–activity relationship revealed that regulating the porous structure and Al distribution of ZSM-5 was an effective strategy to enhance its hydrolytic performance of FAL to LA. Moreover, ZSM-5-OH0.2-H could be reused for three reaction cycles without significant loss in catalytic activity.

Framework aluminum distribution in ZSM-5 zeolite directed by organic structure-directing agents: a theoretical investigation

The distribution of framework Al atoms in zeolite catalysts plays a significant role on dedicating the catalytic activity and product selectivity. Here, the relationship between framework Al distribution and organic structure-directing agents (OSDA) in ZSM-5 zeolite was investigated by the periodic density functional theory (DFT) and ab initio molecular dynamics (AIMD) simulations. It was found that OSDAs with alkyl chains, i.e., tetrapropylammonium (TPA+) and tetraethylammonium (TEA+) cations would lead to the Al atoms mainly distributed at the intersection. While OSDA with pyrazolium ring, i.e., 1,2,4-trimethylpyrazolium (124TMP+), would preferably direct the Al distributed at the sinusoidal channel of ZSM-5. Further energy analysis and electronic structure analysis showed that the Al distribution was not only determined by the Al intrinsic substitution ability of each T sites, but also dominated by the electrostatic interaction between OSDA and zeolite framework. These results indicated that the choice of OSDA used in the hydrothermal synthesis could strongly regulate the Al distribution in zeolite frameworks and further effectively determine the catalytic performance. Therefore, our work would provide a theoretical guidance for the precise design of zeolite catalysis.

Performance Assessment of Non-Newtonian Fluid Flow in Corrugated Channels of Various Profiles: Heat Transfer and Entropy Generation Study

Abstract The present analysis deals with the heat transfer characteristics and entropy generation investigation for a non-Newtonian fluid flowing in a wavy passage having three different corrugation profiles, namely, sinusoidal, trapezoidal, and triangular, having the exact dimensions, amplitude, and wavelength. The discretization of governing equations has been carried out using the finite volume method, and for pressure–velocity coupling SIMPLE algorithm is adopted. Power law model is adopted for modeling the non-Newtonian behavior in the study. The present investigation is reported for the index of power law ranging from 0.4 to 1.6 and Reynolds number varying from 25 to 125. The variation of an average Nusselt number, dimensionless drop in pressure, performance factor, thermal entropy generation, viscous entropy generation, and Bejan number are observed for different values of Reynolds number and power law index. The study helped us in concluding that the value of the average Nusselt number is the highest for a trapezoidal-shaped corrugated channel; on the other hand, drop in pressure is also the highest for a trapezoidal channel. However, if conclusions are to be made based on the performance factor, then at high Reynolds number flow, the sinusoidal-shaped corrugated channel is preferred for shear-thinning fluids, and the triangular-shaped corrugated channel is preferred for shear-thickening fluids, whereas the triangular-shaped corrugated channel is preferred for both the shear-thickening and shear-thinning fluids for a low Reynolds number flow. Entropy generation analysis shows that both the thermal and viscous entropy generations are maximum for a trapezoidal channel followed by the sinusoidal channel and the least entropy generations occur in the case of the triangular channel.

Electron Diffraction Enables the Mapping of Coke in ZSM-5 Micropores Formed during Methanol-to-Hydrocarbons Conversion.

Unveiling the coke formation in zeolites is an essential prerequisite for tackling the deactivation of these catalysts in the transformations of hydrocarbons. Herein, we present the direct mapping of coke in the micropores of ZSM‐5 catalysts used in methanol‐to‐hydrocarbons conversion by single‐crystal electron diffraction analysis. The latter technique revealed a polycyclic aromatic structure along the straight channel, wherein the high‐quality data permit refinement of its occupancy to about 40 %. These findings were exploited to analyze the evolution of micropore coke during the reaction. Herein, coke‐associated signals, which correlate with the activity loss, indicate that the nucleation of coke commences in the intersections of sinusoidal and straight channels, while the formation of coke in the straight pores occurs in the late stages of deactivation. The findings uncover an attractive method for analyzing coke deposition in the micropore domain.

Electron Diffraction Enables the Mapping of Coke in ZSM‐5 Micropores Formed during Methanol‐to‐Hydrocarbons Conversion

AbstractUnveiling the coke formation in zeolites is an essential prerequisite for tackling the deactivation of these catalysts in the transformations of hydrocarbons. Herein, we present the direct mapping of coke in the micropores of ZSM‐5 catalysts used in methanol‐to‐hydrocarbons conversion by single‐crystal electron diffraction analysis. The latter technique revealed a polycyclic aromatic structure along the straight channel, wherein the high‐quality data permit refinement of its occupancy to about 40 %. These findings were exploited to analyze the evolution of micropore coke during the reaction. Herein, coke‐associated signals, which correlate with the activity loss, indicate that the nucleation of coke commences in the intersections of sinusoidal and straight channels, while the formation of coke in the straight pores occurs in the late stages of deactivation. The findings uncover an attractive method for analyzing coke deposition in the micropore domain.

Entropy generation and chemical reaction effects on MHD non-Newtonian nanofluid flow in a sinusoidal channel

This article discusses the effects of entropy generation as well as slip velocity condition on MHD Jeffery nanofluid flow through a porous medium in a channel with peristalsis. We take the effects of mixed convection, heat source, double diffusion and chemical reaction into consideration. Using the assumption of low-Reynolds number and long-wavelength, series solutions of the governing equations are obtained via homotopy perturbation method. Results will be discussed at various parameters of the problem and drawn graphically. Physically, our model is consistent with the motion of digestive juice in the bowel whenever we are going to insert an endoscopy through it. It is noticed that the axial velocity magnifies with an increase in the values of both first and second slip parameters. Meanwhile, the value of the axial velocity reduces with the elevation in the values of both Grashoff and Darcy numbers. On the other hand, the elevation in the value of thermal radiation leads to a reduction in the value of fluid temperature. Furthermore, increasing in the value of order of chemical reaction parameter makes an enhancement in the value of the solutal concentration. It is noticed also that the entropy generation enhances with the increment in the value of Eckert number. The current study has many accomplishments in several scientific areas like engineering industry, medicine, and others. Therefore, it represents the gastric juice motion depiction in the human body when an endoscope is inserted through it.

Numerical Study on Thermal-Hydraulic Performance of Printed Circuit Heat Exchangers during Natural Gas Trans-Critical Liquefaction

Printed Circuit Heat Exchangers (PCHEs) are considered an excellent alternative for the main cryogenic heat exchanger of Floating Liquefied Natural Gas (FLNG) facilities due to their compact structure and strong heat transfer performance. However, it is unclear how to configure the geometry of the PCHE channels to achieve its optimal performance in the trans-critical liquefaction process of natural gas (NG), which is critical for the main heat exchanger. In this paper, we numerically studied the thermal-hydraulic characteristics of PCHEs with different channel types under the specified condition. The results elucidate that all channels have an enhancement of heat transfer near the pseudo-critical point of NG. All the wavy channels could improve the heat transfer performance of PCHEs, where the trapezoidal channel achieves the largest promotion. Compared with the straight channel, the local heat transfer coefficient could be increased by up to 53% in the trapezoidal channel. Additionally, vortex appeared at the bends of the wavy channels, which greatly increase the local friction loss. Among several channels, the total pressure drop of zigzag, fillet and the sinusoidal channel was almost the same, while that of the trapezoidal channel was the largest. Furthermore, we compared the comprehensive performance of different types of channels and found that the benefit of heat transfer enhancement could not offset the penalty of flow deterioration. Our work provides important guidance for the design of PCHEs employed in FLNG.

Analytical and numerical study of capillary rise in sinusoidal wavy channel: Unveiling the role of interfacial wobbling

Capillary rise is ubiquitous in engineering applications and natural phenomena. In straight channels, the dynamics of capillary rise have been thoroughly investigated and are well understood. However, for nonuniform channels of varying radius, the dynamics remain largely unclear. In this study, the capillary rise in a sinusoidal wavy channel is investigated both analytically and numerically. Specifically, the capillary rate-of-rise of water in sinusoidal channels with different contraction frequencies and amplitudes is derived based on the principle of energy conservation. The change in capillary velocity and height over time is further validated by two-phase flow simulations based on the conservative level-set method. The results reveal a strong viscous dissipation in the interfacial region resulting from the wave-like wobbling motion of the liquid–air interface, constituting more than 50% of the total viscous dissipation when the channel profile changes rapidly. Failing to account for this interfacial effect will result in significant overestimations of the capillary velocity and erroneous predictions of the capillary rise curve, typically more than 4 times difference in the capillary velocity and more than 2.5 times difference in the time taken to arrive at the maximum height.

The Late Quaternary geological history of the upper and central Sydney estuary (Australia)

Sydney estuary, on the east coast of Australia, is a small, drowned river valley with a narrow, sinusoidal channel in the upper reaches; a wide, U-shaped valley with large embayments and tributaries in the central section; and an extensive, more marine lower waterway. The estuary has experienced repeated flooding episodes during Quaternary high sea-level stands, in the absence of neotectonism. The present work considered only the upper and central estuary and therefore, potentially records the highest Quaternary sea-level stands.Valuable information on the geology and sedimentology of Sydney estuary stored in poorly-accessible grey literature has been synthesised and summarised in the current work. The first seismic-stratigraphic model was correlated to borehole data to provide a new Late Quaternary geologic history for the upper and central estuary. Limited absolute geochronological data necessitated reliance on stratigraphic correlation and conformity (uniformitarianism).A basal fluvial unit was overlain by a thick, extensive estuarine sequence, which was followed by fluvial marsh and channel sands and muds with minor wood, gravel and peat. Holocene estuarine muds mantled the upper surface of the estuary. Seismic expression was generally consistent with this lithologic subdivision. The thick estuarine unit acted as an important chronological marker horizon and played a critical role in controlling seismic interpretation throughout this part of the estuary. The paleo-estuarine sequence onlaps the modern shoreline and was most likely deposited during the Last Interglacial highstand (MIS 5.5 at 130–115 kyBP) when relative sea-level in Sydney estuary was between ＋4.5 m to ＋5.5 m above the present surface. The channel and marsh sequences were probably backstepping, progradational units in the upper estuary and possibly bayhead deltaic deposits in the central section. An erosional upper surface, as well as the stratigraphic position of these sequences, suggested deposition during a subsequent Interstadial event, most likely the MIS 5.1 at 82–87 kyBP. The knowledge generated by this study provided useful information for greater understanding of Quaternary estuarine evolution on the Australian east coast and for current and future construction projects in and across the estuary.

Spatiotemporal Coke Coupling Enhances para-Xylene Selectivity in Highly Stable MCM-22 Catalysts.

Identifying zeolite catalysts that can simultaneously optimize p-xylene selectivity and feed utilization is critical to toluene alkylation with methanol (TAM). Here, we show that zeolite MCM-22 (MWW) has an exceptional catalyst lifetime in the TAM reaction at high operating pressure, conversion, and selectivity. We systematically probe the catalytic behavior of active sites in distinct topological features of MCM-22, revealing that high p-xylene yield and catalyst stability are predominantly attributed to sinusoidal channels and supercages, respectively. Using a combination of catalyst design and testing, density functional theory, and molecular dynamics simulations, we propose a spatiotemporal coke coupling phenomenon to explain a multistage p-xylene selectivity profile wherein the formation of light coke in supercages initiates the deactivation of unselective external surface sites. Our findings indicate that the specific nature of coke is critical to catalyst performance. Moreover, they provide unprecedented insight into the synchronous roles of distinct topological features giving rise to the exceptional stability and selectivity of MCM-22 in the TAM reaction.

DFT Study on the Combined Catalytic Removal of N2O, NO, and NO2 over Binuclear Cu-ZSM-5

The large amount of nitrogen oxides (N2O, NO, NO2, etc.) contained in the flue gas of industrial adipic acid production will seriously damage the environment. A designed binuclear Cu-ZSM-5 catalyst can be applied to decompose N2O and reduce NO and NO2, purifying the air environment. Using the density functional theory method, the catalytic decomposition mechanisms of N2O, NOX-NH3-SCR, and NOX-assisted N2O decomposition is simulated over the Cu-ZSM-5 model. The results indicate that N2O can be catalytically decomposed over the binuclear Cu active site in the sinusoidal channel. The speed-limiting step is the second N2O molecule activation process. After the decomposition of the first N2O molecule, a stable extra-frame [Cu-O-Cu]2+ structure will generate. The subsequent discussion proved that the NOX-NH3-SCR reaction can be realized over the [Cu-O-Cu]2+ active site. In addition, it proved that the decomposition reaction of NO and NO2 can be carried out over the [Cu-O-Cu]2+ active site, and NO can greatly reduce the energy barrier for the conversion of the active site from [Cu-O-Cu]2+ to the binuclear Cu form, while NO2 can be slightly reduced. Through discussion, it is found that the binuclear Cu-ZSM-5 can realize the combined removal of N2O and NOX from adipic acid flue gas, hoping to provide a theoretical basis for the development of a dual-functional catalyst.

Dynamism of a hybrid Casson nanofluid with laser radiation and chemical reaction through sinusoidal channels

This article studies the impact of laser radiation and chemical reaction with electromagnetic field and electroosmotic flow of hybrid non-Newtonian fluid via a sinusoidal channel. A mathematical model is used to simulate the arisen non-linear partial differential equations (PDEs). By employing the suitable transformations, the system of PDEs is then transformed to a non-linear system of ordinary differential equations (ODEs). The impact of the pertinent parameters on the pressure rise, velocity profile, streamlines and temperature distribution has been discussed. It has been noticed that the laser parameter enhances the fluid flow and the temperature distribution. This result occurs due to the impact of laser radiation that decreases the blood viscosity which in turn implies an increase in the fluid velocity leading to an enhancement in the heat transfer inside the fluid layers. The technique of laser radiation plays an important role in treating many viral and autoimmune diseases. The current study of radiation has the intention to help inhibit bacterial growth, increase oxygen binding to the blood, transport oxygen to organs and activate white blood cells.

Effect of zeolite structure and addition of steam on naphtha catalytic cracking to improve olefin production

In this study, steam catalytic cracking of dodecane (a model representative of naphtha) was investigated both with and without steam. The reaction utilized the different 3D sinusoidal microporous channels in submicron ZSM-5 and BEA zeolite crystals to convert dodecane to light olefins. Although both synthesized submicron catalysts (400–500 nm) have similar Brønsted/Lewis acid ratios, the BEA zeolite exhibited higher surface acidity than ZSM-5 zeolite. In addition, the steam addition has significantly affected the zeolites structure, even though their cracking activity was not affected. However, the zeolites structural modification has shown significant effect on the pore shape selectivity which result in different light olefins yields. During catalytic cracking in the absence of steam, hydrogen transfer reaction was less favored over BEA zeolite, which result in higher light olefins selectivity and dry gas formation than with ZSM-5 zeolite. In the presence of steam, ZSM-5 pore-shape modification favored the monomolecular cracking pathway leading to achieving higher light olefin yield than that observed over BEA zeolite. The study demonstrated that ethylene/propylene ratio (E/P) is impacted by zeolite structure which is affected by the steam addition during the reaction.

Enhancing the catalytic performance of H-ITQ-13 zeolite in the conversion of methanol to olefins through regulating the aluminum distribution in its framework

Herein, K+ was added in the synthesis gel to regulate the distribution of acid sites in the ITQ-13 zeolite and enhance its catalytic performance in the conversion of methanol to olefins (MTO). The results indicate that a proper content of K+ ions in the synthesis gel can not only expedite the crystallization of ITQ-13 zeolite, but also significantly decrease the proportion of paired Al and distribute more Al atoms in the 10-ring sinusoidal channel out from the intersection cavity. Accordingly, over the H-ITQ-13(0.3 K) zeolite prepared using the synthesis gel with a KCl/Al2O3 molar ratio of 0.3, the alkene cycle of MTO keeping to the dual cycle hydrocarbon pool (HCP) mechanism is preferably enhanced, whereas the hydride transfer and aromatization reactions are substantially suppressed. As a result, H-ITQ-13(0.3 K) exhibits much longer catalytic lifetime and higher selectivity to propene and butene, in comparison with the H-ITQ-13 counterpart obtained without adding K+.

Correlation of Brønsted acid sites and Al distribution in ZSM-5 zeolites and their effects on butenes conversion

The relationship between Brønsted acid sites and framework Al distribution in the 10-membered ring (10-MR) straight and sinusoidal channels and their channel intersections in ZSM-5 zeolites were investigated using a range of analytical techniques. Spatial confinement in the straight and sinusoidal channels not only strengthens interactions between Brønsted acid sites and guest molecules, but also promotes proximity and interaction between Brønsted acid sites with the same chemical shift, enhancing their strengths. Stronger Brønsted acid sites do not benefit the conversion of butenes in oligomerization reactions owing to restriction of their migration and diffusion. However, the Al sites at channel intersections are more spacious, and the lower confinement therein favors selectivity for butene oligomerization products (C8) and n-butene aromatization products (BTX and C9 + aromatics).

Numerical simulation on flow boiling characteristics in sinusoidal channels of airborne micro heat exchanger

With the miniaturization of airborne system, heat dissipation has become a critical issue. Since sinusoidal channel can enhance flow disturbance, it has a stronger heat exchange capacity than that of straight channel. However, flow boiling characteristics in sinusoidal channel are more complex. Here, numerical simulations of flow boiling in sinusoidal and straight microchannels are conducted based on the VOF model with the inner diameter of 1 mm, mass flux of 500 kg/m2 s and heat flux of 50 kW/m2. The effects of channel structure and hypergravity are obtained. The simulation results indicate that bubble evolution in sinusoidal channel is more complex than that in straight channel, and bubbles are more likely to coalesce, deform and break. Vortices appear in sinusoidal channel and disrupt the near-wall boundary layer. Bubble evolution combined with vortices affect the flow boiling performances. For straight channel, dryout is less likely to occur, while for sinusoidal channel, it is more likely due to more drastic flow changes. Furthermore, the transition of flow patterns is faster under hypergravity. For sinusoidal channel, flow patterns transform earlier into slug and circular flows.