The paper presents the results of computational analysis of the stress-strain state of reinforced concrete spans of the railway (single-track railway line) overpass over the highway, under specified loads using spatial finite element models. The static load consists of a cohesion of three TEM-18 diesel locomotives and two loaded gondola cars (up to 25 tons per axle). The purpose of this study was to ensure reliable and safe operation of artificial structures on the railroads, as there is a constant increase in transit freight trains from China through the territory of Kazakhstan to near and far abroad, and often the load on the axle reaches 25 tons, and sometimes larger values – up to 27 tons per axle. The results of the study are recommended to be used for inspections and tests of typical girder bridge spans, as well as in the case of monitoring their technical condition with increasing operational loads.