This paper investigates the measurement accuracy of unmanned aerial vehicle-based oblique photography (UAVOP) in bridge deformation identifications. A simply supported concrete beam model was selected and measured using the UAVOP technique. The influences of several parameters, such as overall flight altitude (h), local shooting distance (d), partial image overlap (λ), and arrangement of control points, on the quality of the reconstructed three-dimensional (3D) beam model, were presented and discussed. Experimental results indicated that the quality of the reconstructed 3D model was significantly improved by the fusion overall-partial flight routes (FR), of which the reconstructed model quality was 46.7% higher than those with the single flight route (SR). Despite the minimal impact of overall flight altitude, the reconstructed model quality prominently varied with the local shooting distance, partial image overlap, and control points arrangement. As the d decreased from 12 m to 8 m, the model quality was improved by 48.2%, and an improvement of 42.5% was also achieved by increasing the λ from 70% to 80%. The reconstructed model quality of UAVOP with the global-plane control points was 78.4% and 38.4%, respectively, higher than those with the linear and regional control points. Furthermore, an optimized scheme of UAVOP with control points in global-plane arrangement and FR (h = 50 m, d = 8 m, and λ = 80%) was recommended. A comparison between the results measured by the UAVOP and the total station showed maximum identification errors of 1.3 mm. The study’s outcomes are expected to serve as potential references for future applications of UAVOP in bridge measurements.