Background: Around 7% of under-five aged children in the Eastern Mediterranean are overweight, and there are higher rates in Gulf Cooperation Council (GCC) countries. This had led the GCC to impose policies that aim to decrease obesity, overweight, and diabetes rates. The objective of this research is to measure the impact of one such implemented policy to reduce obesity, i.e. sin taxes applied to sugar-sweetened beverages (SSB) in GCC. Methods: The impact of sin taxes on SSB has been measured using a panel data set that covers sales volumes of soft drinks in GCC countries from 2010 to 2020. Results: Growth rate of sales volumes decreased from 5.44% to 1.33% in Saudi Arabia, 7.37% to 5.93% in United Arab Emirates, and 5.25% to 5.09% in Bahrain from 2016 to 2017; sin taxes were implemented in these countries in 2017. In Qatar and Oman, sin taxes were implemented in 2019, and a reduction in sales volumes was observed from 2018 to 2019 (Qatar: 2.30% to 3.78%; Oman: 3.60% to 2.99%). Kuwait was the last GCC country to implement sin taxes in 2020. Growth rate of sales volumes decreased from 6.31% to 5.47% from 2019 to 2020. Conclusions: Awareness campaigns should promote the reduction of the consumption of SSB and substitute with more consumption of water, unsweetened milk for children, fresh fruits and vegetables. These recommendations align with the recommended priority actions by the World Health Organization for the strategy on nutrition for the Eastern Mediterranean Region 2020-2030.