Simultaneous Actions Research Articles

An opportunistic group maintenance model for the multi-unit series system employing Jaya algorithm

Opportunistic maintenance approaches deal with performing group preventive maintenance (PM) on the other units in a series system due to the intervention of any scheduled PM of a component. Simultaneous maintenance actions show better economic performance due to the direct reduction of downtime costs and production losses. However, it is uneconomical to perform maintenance on all units simultaneously. To address this issue, various simulation and optimization approaches including Markov chains, genetic algorithm etc. have been applied in order to achieve optimum solutions in group maintenance models. However, most of these strategies suffer from intractability as the problem size increases. In the present paper, we develop an efficient opportunistic grouping methodology for the multi-unit series system while considering imperfect preventive maintenance. The aim is to obtain an optimum PM interval and grouping of units to minimize the expected total system maintenance cost per unit time during the mission. A recently developed meta-heuristic named ‘Jaya algorithm’ is applied to optimize the objective function. The effectiveness of the proposed approach is examined with three maintenance models: single unit model, mono-group model and the proposed opportunistic group model. Results reveal that the proposed group maintenance model results in 19% cost savings as compared to the mono-group model and 71% compared to the single component maintenance model.

Insights Into Mechanisms of Tumor and Immune System Interaction: Association With Wound Healing.

A large number of studies have presented a great deal of information about tumor and immune system interaction. Nevertheless, the problem of tumor evasion from the immune reaction is still difficult to resolve. Understanding the ways in which immunosuppressive tumor microenvironment develops and maintains its potential is of utmost importance to ensure the best use of the suppressed immune functions. The study presents a review covering the data on tumor-associated antigens, mechanisms of tumor evasion from the immune reactions, and search for common immunosuppressive processes of tumor growth and normal wound healing. The study discusses the important role of monocytes/macrophages in the regulation of immune system reactions. We suggest that the simultaneous actions of growth factors and pro-inflammatory cytokines may result in the suppression of the immune system. The study describes intracellular signaling molecules that take part in the regulation of the myeloid cell functions. If the hypothesis is proved correct, the indicated interaction of cytokines could be regarded as a prospective target for antitumor therapy.

Performance of amine cured epoxy and silica fume modified cement mortar under military airbase operating conditions

Conventional concrete at military airbase is reported to experience premature scaling damage due to repeated exposures to hydrocarbon fluids (HFs), rainwater and high thermal shocks simultaneously. The present study examines the performance of amine cured epoxy and reactive silica fume (SF) modified Portland cement (PC) mortar and unmodified PC mortar under laboratory simulated military airbase operating conditions, which simultaneously applied HFs, water and high temperature on the surfaces of the considered mortar specimens repeatedly. Unmodified PC mortar was observed to experience saponification, thermal cracks and scaling when exposed to the combined actions of HFs and thermal cycles; however, the modified PC mortar sustained those adverse conditions. After 80 cycles of exposure to the simultaneous actions of HFs and high temperature, the unmodified plain mortar lost 80.48% of the compressive strength. Whereas, the 3-day and 28-day old epoxy and SF modified PC mortar lost 41.70% and 36.15% of the compressive strength showing considerable resilience against the military airbase working conditions, respectively. Epoxy and SF modified PC mortar retained more than the required minimum compressive strength for military airbase even after 80 cycles of exposure, however, the unmodified PC mortar failed to do so. FTIR and XRD analyses, showed that compounds created by interactions amongst epoxy, SF and PC did not react with HFs even at high temperature. Epoxy notably protected crystalline mineral compounds such as ettringite, portlandite, quartz, alite, belite mullite and calcite in PC from hydrocarbon attacks but failed to prevent their thermal decomposition, as epoxy in mortar was observed to deform, swell and plasticized after thermal exposures. Mass loss characteristics, depths of HFs attack, effect of epoxy to cement (E/C) ratio on the durability, residual compressive strength and microstructures after the considered exposures are also reported.

Cooperation in bottlenose dolphins: bidirectional coordination in a rope-pulling task.

In comparison with terrestrial animals, such as primates, there is limited empirical evidence for cooperative behavior in marine mammals under experimental conditions. In this study, we used a cooperative rope-pulling task to investigate how bottlenose dolphins (Tursiops truncatus) coordinate their behavior with a partner. Dolphins successfully learned and were able to perform the task, even when one subject started after the other. In the no-delay condition (i.e., both subjects sent at the same time), one pair of dolphins showed coordinated behaviors. When pairs were successful in solving the task in the delay condition (i.e., one individual sent later than the other), the initiators (i.e., first individual sent) were likely to wait for the follower to arrive, and the follower was likely to swim faster when the initiator did not wait and started pulling the rope alone. These coordinated behaviors might help resolve the given cooperative task. Our results suggest that bottlenose dolphins learn to coordinate their behaviors via trial and error and recognize the necessity of performing simultaneous actions with a partner to successfully accomplish cooperative tasks. In addition, both partners showed behavioral changes over many trials of no-delay and delay conditions, suggesting that bidirectional coordination occurred in the cooperative task.

INCREASE OF EFFICIENCY OF COMPENSATION OF THE ACTIVE COMPONENT OF COMBINED INTERFERENCE

Context. Under simultaneous actions of the active noise and passive interference, the latter de-correlates the active component ofthe combined interference, which significantly limits its compensation. In addition, when the active interference acts on the sidelobes of the antenna pattern when scanning a spaced-apart antenna system, inter-channel delays of interfering signals occur, whichalso leads to the degradation of compensation.Objective. Improving the efficiency of compensation of the active component of the combined interference acting on the sidelobes of the radiation pattern under simultaneous effect of the passive interference.Method. An improved algorithm for processing radar signals with direct calculation of the weight factor of the adaptive spatialfilter and matched filtering of the signals of the main and compensation channels. The effect of passive interference on the process ofadapting the weight factor of the spatial filter is eliminated using notch filters.Results. A block diagram of an improved spatial filter has been developed. A mathematical model has been created. In the processof simulation, it was found that the proposed algorithm for processing radar signals in the side-lobe sector of the antenna pattern[3°–30°] relative to the main beam provided a gain in the compensation of active noise interference of about 6.0 to 6.4 dB as comparedto the known adaptive spatial filter circuit.Conclusions. The scientific novelty of the work is in improving of the algorithm for processing radar signals by parallel calculationof the weight factor of the spatial filter using notch filters and matched filtering of the signals of the main and compensationchannels.The practical novelty consists of creating a structural scheme and a mathematical model of an improved adaptive spatial filter.The simulation results confirmed the relatively high efficiency of the proposed radar signal-processing algorithm. The results obtainedcan be used in the design or modernization of radars for various purposes.

Modelling and Control of Mechatronics Lines Served by Complex Autonomous Systems.

The aim of this paper is to reverse an assembly line, to be able to perform disassembly, using two complex autonomous systems (CASs). The disassembly is functioning only in case of quality default identified in the final product. The CASs are wheeled mobile robots (WMRs) equipped with robotic manipulators (RMs), working in parallel or collaboratively. The reversible assembly/disassembly mechatronics line (A/DML) assisted by CASs has a specific typology and is modelled by specialized hybrid instruments belonging to the Petri nets class, precisely synchronized hybrid Petri nets (SHPN). The need of this type of models is justified by the necessity of collaboration between the A/DML and CASs, both having characteristics and physical constraints that should be considered and to make all systems compatible. Firstly, the paper proposes the planning and scheduling of tasks necessary in modelling stage as well as in real time control. Secondly, two different approaches are proposed, related to CASs collaboration: a parallel approach with two CASs have simultaneous actions: one is equipped with robotic manipulator, used for manipulation, and the other is used for transporting. This approach is correlated with industrial A/D manufacturing lines where have to transport and handle weights in a wide range of variation. The other is a collaborative approach, A/DML is served by two CASs used for manipulation and transporting, both having simultaneous movements, following their own trajectories. One will assist the disassembly in even, while the other in odd workstations. The added value of this second approach consists in the optimization of a complete disassembly cycle. Thirdly, it is proposed in the paper the real time control of mechatronics line served by CASs working in parallel, based on the SHPN model. The novelty of the control procedure consists in the use of the synchronization signals, in absence of the visual servoing systems, for a precise positioning of the CASs serving the reversible mechatronics line.

Interference Between Present and Absent Performers

Interference between Present and Absent Performers: Time-Specific Performance as Phenomenal Experience The performance of the play Lise & Otto employed digital technology in an innovative and surprising way. Two performers presented their characters in two locations that were connected by fibre optic cables. The audiences, situated in two suburbs in Stockholm, saw either the actress or the actor live in front of them, while the other performer's image and voice were transmitted digitally. The simultaneous actions emphasized a cleavage of space - symbolic in a play about atomic fission - and created a yearning for the absent performer. This phenomenon can be described as time-specific performance, analogous to site-specific performance, while at the same time questioning the paradigm of presence as as a condition of theatrical events. The article argues for an extension of the theoretical concepts of theatre studies in order to cope with contemporary technological innovations, time-specificity, and unexpected theatrical experiences.

Cholesterol enriched diet suppresses ATF6 and PERK and upregulates the IRE1 pathways of the unfolded protein response in spontaneously hypertensive rats: Relevance to pathophysiology of atherosclerosis in the setting of hypertension

Many studies have been dedicated to hypertension and hypercholesterolemia, as they are the primary conditions that influence the unfolded protein response (UPR). However, the concurrent effects of these two factors are unknown. Our research used spontaneously hypertensive rats (SHR) fed a cholesterol enriched diet (CED) as model of atherosclerosis formation to discover what effect the simultaneous actions of hypertension and hypercholesterolemia have on the UPR. The combination of hypertension and consumption of a CED (not the CED alone) caused the formation of early atherosclerotic features. Both increased expression of the CCAAT-enhancer-binding protein (CHOP) and the insulin induced gene 1 (INSIG1), which is the target gene of the sterol regulatory element-binding protein 1-c (SREBP1-c), and decreased expression of the spliced x-box binding protein1 (sXBP1) mRNA were observed in the SHR fed a CED. Cholesterol overload strongly suppressed glucose regulated protein 78 (GRP78), glucose regulated protein 94 (GRP 94), and the expression of CHOP and INSIG1 mRNA in both normotensive and hypertensive rats. Unlike other UPR factors, the sXBP1 mRNA expression was strongly downregulated in SHR fed a normal diet but upregulated in those fed a CED. The changes to UPR in the SHR fed a CED were associated with improvement of the initially impaired heart function of the rats.

Inter-Authority and Cross-Border Cooperation Using the Tetra Digital Radio Network

Introduction:The Tetra digital radio network enables a secure and encrypted environment for verbal and minimal data (SDS, Unit Alert) communication. In Finland (population 5.6 million), the technology has been in use since 2002, and the network currently has close to 40,000 end-users representing several authorities including emergency medical services and health care, police, fire and rescue services, Border Guard, Customs, and defense forces. The national dispatch authority uses the network to dispatch and communicate with EMS, police, and rescue services, and inter-authority talk groups have been designed to enable direct communication between each or all actors as needed. On a daily basis, the network transmits more than 7.5 million messages and 150,000 verbal contacts. The system has proved to be extremely stable during mass casualty incidents needing simultaneous actions by hundreds of individuals representing several authorities. Finland, Sweden, and Norway have common borders in the north, which EMS units routinely cross on a daily basis responding to urgent missions. Both Sweden and Norway have nationally implemented the Tetra communication network, but are using different operators.Methods:The need to facilitate communication between Tetra end-users in the Nordic countries using each other’s networks resulted in an inter-system-interface (ISI) solution enabling network roaming. Between Finland and Norway, the mechanism was launched late in 2017 and is being implemented between Finland and Sweden in 2018.Results:Pending configuration of necessary talk groups, the system will be functional and in use in 2019.Discussion:Based on agreements on cross-border emergency assistance between Nordic countries in mass-casualty and other major incidents, the countries have developed national capacities to deploy response teams to neighbor countries for on-scene assistance and medical evacuation. Planning of necessary talk groups is in progress, and practical testing will be performed during the Barents rescue exercise hosted by Sweden in 2019.

Hand-Foot Coupling: An Advantage for Crossed Legs.

It is difficult to perform distinct, simultaneous motor actions with the ipsilateral hand and foot; for example, clockwise circles with the right hand and counter-clockwise circles with the right foot. By chance, we discovered that this hand-foot coupling task is easier when seated with legs crossed. We consider various explanations. First, that there are reduced demands on the contralateral hemisphere when the motor programme of the right foot is executed on the left side of the body. Second, that the legs-crossed scenario is easier because movements are symmetrical with respect to body midline. By considering related motor actions, we conclude that neither of these explanations provides a full account. Thus, we suggest a third explanation, which is that coupling effects are reduced by virtue of increased postural stability and reduced anticipatory postural adjustments.

Low Power Restricted Boltzmann Machine Using Mixed-Mode Magneto-Tunneling Junctions

This letter discusses mixed-mode magneto tunneling junction (m-MTJ)-based restricted Boltzmann machine (RBM). RBMs are unsupervised learning models, suitable for extracting features from high-dimensional data. The m-MTJ is actuated by the simultaneous actions of voltage-controlled magnetic anisotropy and voltage-controlled spin-transfer torque, where the switching of the free-layer is probabilistic and can be controlled by the two. Using m-MTJ-based activation functions, we present a novel low area/power RBM. We discuss online learning of the presented implementation to negate process variability. For MNIST hand-written dataset, the design achieves ~96% accuracy under expected variability in various components.

Sociomedical problems of overwork-related deaths and disorders in Japan.

ObjectivesCerebrovascular and cardiovascular diseases (CCVDs) and mental disorders, including suicide, are prevalent among overworked individuals in Japan. The 2014 legislation regarding the prevention of overwork‐related deaths and disorders has accelerated the research in this field and ultimately the implementation of preventive actions.MethodsTo understand the current problematic situations, the Research Center for Overwork‐Related Disorders of the National Institute of Occupational Safety and Health, Japan, conducted analyses of compensated claims for overwork‐related CCVDs and mental disorders that were recognized from January 2010 to March 2015.ResultsThe majority of CCVD cases were the men in their 50s. Transport and postal activities was the highest risk industry. Cerebrovascular cases were higher than cardiovascular ones. Long working hours was the principal factor for CCVDs. The mental disorder cases comprised approximately 70% men and affected younger age groups (peak in the third decade) with various industries at risk. In men, there was an almost equal number of F3 (Mood [affective] disorders) and F4 (Neurotic, stress‐related, and somatoform disorders) diagnoses according to the 10th revision of the International Classification of Diseases and Related Health Problems. A larger number of women were diagnosed to have F4. The mental disorder cases were associated not only with long working hours, but also with injuries and disasters as well as interpersonal conflict at work.ConclusionsMultiple, simultaneous actions need to be made by employees, employers, researchers, and the authorities to achieve the goal of reducing the number of workers suffering from the overwork‐related CCVDs and mental disorders.

High cycle fatigue and ratcheting interaction of laser powder bed fusion stainless steel 316L: Fracture behaviour and stress-based modelling

Variations in the physical and mechanical properties of parts made by laser power bed fusion (L-PBF) could be affected by the choice of processing or post-processing strategies. This work examined the influence of build orientation and post-processing treatments (annealing or hot isostatic pressing) on the fatigue and fracture behaviours of L-PBF stainless steel 316L in the high cycle fatigue region, i.e. 104–106 cycles. Experimental results show that both factors introduce significant changes in the plastic deformation properties, which affect fatigue strength via the mechanism of fatigue-ratcheting interaction. Cyclic plasticity is characterised by hardening, which promotes mean stress insensitivity and improved fatigue resistance. Fatigue activities, involving the initiation of crack at defects and microstructural heterogeneities, are of greater relevance to the longer life region where the global deformation mode is elastic. As the simultaneous actions of ratcheting and fatigue generate complex nonlinear interactions between the alternating stress amplitude and mean stress, the fatigue properties could not be effectively predicted using traditional stress-based models. A modification to the Goodman relation was proposed to account for the added effects of cyclic plasticity and was demonstrated to produce good agreement with experimental results for both cyclic hardening and softening materials.

Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides

ABSTRACTBackground: Cyclic dinucleotides (cyclic di-guanosine monophosphate (c-di-GMP) and cyclic di-adenosine monophosphate (c-di-AMP)) and lipopolysaccharides (LPS) are pathogen-associated molecular patterns (PAMPs). Individual impacts of PAMPs on immune system have been evaluated, but simultaneous actions of multiple PAMPs have not been studied. Objective: Examination the effects of cyclic dinucleotides and Porphyromonas gingivalis LPS on gingival epithelial cytokine response. Methods: Human gingival keratinocytes (HMK) were incubated with 1, 10, and 100 µM concentrations of c-di-GMP and c-di-AMP, either in the presence or absence of P. gingivalis LPS. Intra- and extracellular levels of interleukin (IL)-1β, IL-8, IL-1Ra, monocyte chemoattractant protein (MCP)-1, and vascular endothelial growth factor (VEGF), were measured using the Luminex technique. Results: LPS decreased extracellular IL-8 levels, while the presence of c-di-AMP inhibited this effect. Incubating HMK cells with c-di-AMP (alone or with LPS) elevated the extracellular level of MCP-1. Extracellular VEGF level increased when cells were incubated with LPS and c-di-GMP together, or with c-di-AMP alone. LPS and c-di-AMP suppressed intracellular IL-1β levels. The c-di-AMP elevated intracellular levels of IL-1Ra. Conclusion: c-di-AMP and, to a lesser extent, c-di-GMP regulate keratinocyte cytokine response, either as an aggregator or as a suppressor of LPS, depending on the cytokine type.

Unique decomposition of homogeneous languages and application to isothetic regions

A language is said to be homogeneous when all its words have the same length. Homogeneous languages thus form a monoid under concatenation. It becomes freely commutative under the simultaneous actions of every permutation group on the collection of homogeneous languages of length n ∈ ℕ. One recovers the isothetic regions from (Haucourt 2017, to appear (online since October 2017)) by considering the alphabet of connected subsets of the space |G|, viz the geometric realization of a finite graph G. Factoring the geometric model of a conservative program amounts to parallelize it, and there exists an efficient factoring algorithm for isothetic regions. Yet, from the theoretical point of view, one wishes to go beyond the class of conservative programs, which implies relaxing the finiteness hypothesis on the graph G. Provided that the collections of n-dimensional isothetic regions over G (denoted by |G|) are co-unital distributive lattices, the prime decomposition of isothetic regions is given by an algorithm which is, unfortunately, very inefficient. Nevertheless, if the collections |G| satisfy the stronger property of being Boolean algebras, then the efficient factoring algorithm is available again. We relate the algebraic properties of the collections |G| to the geometric properties of the space |G|. On the way, the algebraic structure |G| is proven to be the universal tensor product, in the category of semilattices with zero, of n copies of the algebraic structure |G|.

Pit Crew Approach to Pre Hospital Trauma Resuscitation

<p><strong>Introduction</strong></p><p>Pre hospital trauma care is often delivered by dual crewed ambulances supported by additional resources as necessary and available. Coordinating resuscitation of a critically injured patient may require multiple simultaneous actions. Equally, a large number of practitioners can hinder patient care if not coordinated.</p><p><strong>Aims</strong></p><p>To describe a multi disciplinary, scaleabe approach to pre hospital trauma care suitable for small and large multi disciplinary teams. Methods The MCI medical team (as part of Motorsport Rescue Services) is a PHECC-registered multidisciplinary team, which provides medical cover at Motorcycle road racing events in Ireland. The MCI medical team has significant experience of major trauma and routinely performs prehospital anaesthesia for trauma patients. We have evolved a pit crew approach to trauma care with pre defined roles and interventions assigned to a five person team, three clinical members, a scribe and a team lead. The approach is both scalable and collapsible, meaning that if multiple patients are present, roles can be merged; if additional clinical input is required, roles can also be supplemented. Each team member carries equipment and medications specific to their role, allowing efficiencies at the patients side.</p><p><strong>Results</strong></p><p>The pit crew approach to pre hospital trauma care has evolved over a decade and is routinely implemented at motorcycle road races in Ireland.</p><p><strong>Conclusions</strong></p><p>The pit crew trauma approach, although applicable to a pre defined five person team in unique circumstances, may also be applicable to ad hoc clinical teams that typically form in the pre hospital arena.</p>

Population genetics and genotyping as tools for planning rat management programmes

Brown rats are a prolific synanthropic pest species, but attempts to control their populations have had limited success. Rat population dynamics, dispersal patterns, and resistance to rodenticides are important parameters to consider when planning a control programme. We used population genetics and genotyping to investigate how these parameters vary in contrasting landscapes, namely one urban and two rural municipalities from eastern France. A total of 355 wild brown rats from 5 to 6 sites per municipality were genotyped for 13 microsatellite loci and tested for mutations in the Vkorc1 gene which confers resistance to some rodenticides. Results revealed a strong genetic structure of the sampled rat populations at both regional (between municipalities) and local (between sites within municipalities) levels. A pattern of isolation by distance was detected in the urban habitat and in one of the rural municipalities. GeneClass and DAPC analyses identified 25 (7%) and 36 (10%) migrants, respectively. Migrations occurred mostly between sites within each municipality. We deduced that rat dispersal is driven by both natural small-scale movements of individuals and longer-distance (human-assisted) movements. Mutation Y139F on gene Vkorc1 was significantly more prevalent in rural (frequency 0.26–0.96) than in urban sites (0.00–0.11), likely due to differences in selection pressures. Indeed, pest control is irregular and uncoordinated in rural areas, whereas it is better structured and strategically organised in cities. We conclude that simultaneous pest control actions between nearby farms in rural habitats are highly recommended in order to increase rat control success while limiting the spread of resistance to rodenticides.

Essential oils from tropical medicinal herbs and food plants inhibit biofilm formation in vitro and are non-cytotoxic to human cells.

The biofilm inhibition and eradication potential of essential oils (EOs) extracted from six tropical medicinal herbs and food plants [Psiadia arguta (PA), Psiadia terebinthina (PT), Citrus grandis (CGp), Citrus hystrix (CH), Citrus reticulata (CR), and Cinnamomum zeylanicum (CZ)] were assessed. The mechanism of inhibition was studied via quenching of efflux pump. Cytotoxicity was evaluated using Artemia salina assay and cell lines [human cervix carcinoma (HeLa), human lung fibroblast (MRC-5), and murine melanoma (B16F10)]. EOs of CH, CR, PA, and PT were found to be prospective antibiofilm agents (IC50 of 0.29, 0.59, 0.22, and 0.11mg/mL against Staphylococcus epidermidis; 0.39, 0.54, 0.09, and 0.13mg/mL against Escherichia coli; and 0.54, 0.90, 0.44 and 0.51mg/mL against Candida albicans for CH, CR, PA, and PT, respectively). The simultaneous actions of the EOs and efflux pump inhibitor impacted on the resistance of the biofilms. LC50 of the EOs ranged from 223 to 583µg/mL against A. salina. The non-cytotoxic concentration of the EOs varied from 200 to 300µg/mL (HeLa and MRC-5), and 150-200µg/mL (B16F10). EOs from these tropical medicinal herbs and food plants are useful sources of new antimicrobials with low cytotoxicity which could open new horizons in the drug development process.

Posterior lingual frenulum in infants: occurrence and maneuver for visual inspection

ABSTRACT Purpose: to verify the occurrence of posterior or submucosal lingual frenulum and evaluate the efficiency of a special maneuver for its visual inspection. Methods: an experimental study including 1,715 healthy infants, in which prematurity, perinatal complications, craniofacial anomalies neurological disorders, and visible genetic syndromes were the exclusion criteria. A clinical examination was performed by means of a maneuver that consisted in rising the lateral margins of the tongue to visualize the anatomical characteristics of the lingual frenulum. In some of the infants, a special maneuver was performed to assist visualization of posterior lingual frenulum, since its visualization was not possible. The maneuver consisted in two simultaneous actions: elevating and pushing the tongue back. Results: 558 infants (32.54%), out of the 1,715 had posterior frenulum, which required the special maneuver that consisted in both elevating and pushing the tongue back, simultaneously. Conclusion: the occurrence of posterior lingual frenulum was high and the special maneuver consisted in elevating and pushing the tongue back proved to be efficient to visualize the posterior lingual frenulum.

INVESTIGATION INTO THE CONDITIONS CAUSING TERMINAL-BOLTED TRACK GAUGE WIDENING AND CONSIDERATION OF IT IN THE CRITICAL GAUGE CALCULATION

In the current regulatory document UZ – Instructions for the device and the content Railways of Ukraine, the largest permissible value of track gauge – 1548mm, which was scientifically proved only for use as a sub-rail base wooden sleepers due to the possibility of the occurrence under certain conditions of falling of the wheels of the rolling stock, rails unfolding through the availability of pulling and screws. But, for tracks with concrete sleepers, rails unfolding not possible due to the hard bolt pressing pads to the sleepers and rails. In the presence on rails in the undocking way with reinforced concrete sleepers of the considerable sizes of lateral wear or corrosion damages of metal substrates in a zone of fastening of mortgage bolts, the certain value of dangerous width of a rail track is underestimated and economically inexpedient because of need of premature replacement of rail lashes. Therefore there is a need to clarify and justify the maximum allowable value of the width of a rail track with rail on the basis of concrete ties. To achieve this goal, it is necessary to conduct experimental studies with the worst real conditions of pressing the rails to the sleepers. The acute scientific task of determining maximum dangerous railway track gauge with reinforced concrete sleepers and fastenings of terminal-bolted track type has been set and solved on the base of the analysis of previous researches of leading scientists and scientific-research organizations of railway transport. Taking into account simultaneous actions of lateral force and track thrust force as well as all known tolerances and influences under the conditions of new maintenance profile of railway wheels of the most popular rolling stock, all the obtained results and recommendations have been differentiated according to the ranges of railway sections traffic volume and make it possible to increase running speeds and lifetime of long-welded rails substantially to use their service life to the maximum.