The paper presents the solution to the problem of numerical simulation of thermal comfort in domestic premises. Three thermal bridges have been selected as the key parameters for enclosure structures. They have been calculated on the basis of thermographic studies of a group of typical brick blocks of flats which are located in the city of Tyumen. The considered thermal bridges are as follows: the insulation connections in the outer wall openings; insulation in the outer wall corners; insulation in the outer wall-floor structure connections. The functional connections of the thermal comfort level versus the values of the thermal bridge parameters have been determined. The study has resulted in an express-method of the expert assessment of thermal comfort in domestic premises based on the total assessment of thermal bridges in enclosure structures. The method can be used for a complete structural survey of residential buildings, and in examination of building operation and heat-protective properties of enclosure structures.