We thank Dr Brown for her interest in our editorial. She is, of course, correct in stating that the vast majority of cases of laryngospasm are managed successfully with the application of CPAP and other simple manoeuvres. The thrust of our article was, however, the serious case of laryngospasm, when these simple manoeuvres have been tried and the situation is slipping out of control, that is, when the oxygen saturation continues to drop rapidly or the patient becomes bradycardic before intravenous access has been achieved. We did not intend to discuss those simple manoeuvres in detail. Dr Brown states that ‘complete laryngospasm can quickly progress to hypoxia and bradycardia, and intubation may become necessary’. We are aware that many anaesthetists may choose to intubate at this stage and this may resolve the situation. However, if unsuccessful, especially in the older child or adult, valuable time is wasted. We feel that it is an important principle in the management of such a situation that we must not get fixated on intubation, but on oxygenation. Is full muscle relaxation necessary to facilitate intubation? We state in our editorial that the time to maximal twitch depression for intramuscular suxamethonium is in the region of 3–4 min, but that ‘oxygenation is the initial goal, and therefore, full relaxation is probably not necessary’. This relates specifically to the ability to oxygenate by CPAP and manual inflation of the lungs, not to intubation. Dr Brown states ‘this implies that one need not wait for the full effects of suxamethonium before attempting intubation’. We have based our logic on the work of Donati [1], that central muscles such as the muscles of the larynx and diaphragm relax earlier than peripheral muscles and therefore oxygenation by the application of tight CPAP and manual inflation will be possible before full relaxation is present at the adductor pollicis muscle. Therefore, it does not necessarily follow that one can intubate at this point. We believe that when faced with this life-threatening situation one should administer suxamethonium by one of the routes discussed and maintain CPAP until laryngospasm breaks. Oxygenate and then, if necessary, intubate. Likewise, the use of topical lidocaine in this situation, although reported, could make the situation worse and, again, wastes precious time. The rapidly deteriorating child or adult allows no time to ‘consider’ different options. The anaesthetist must have a plan and act on that plan rapidly. Experience is little protection in this situation. This can happen to anyone, at any time and it is our belief that the administration of suxamethonium by the intramuscular, intra-osseous or intralingual route is of paramount importance to prevent serious complications from laryngospasm.
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