Simple Linear Regression Analysis Research Articles

Predicting surgical efficacy and diagnosing histological inflammation: the clinical significance of prostate exosome proteins in benign prostatic hyperplasia.

Benign prostatic hyperplasia (BPH) is one of the most common causes of lower urinary tract symptoms (LUTS) among the aging male population. Recent studies have shown that histological inflammation (HI) plays a significant role in BPH, with prostatic exosomal protein (PSEP) identified as a potential biomarker for prostate diseases. Therefore, this study aimed to explore the effect of HI on LUTS in patients with BPH, and to further explore the clinical value of PSEP as a diagnostic biomarker of BPH complicated with HI and whether PSEP could be used as an index to predict the improvement of LUTS after operation. This study was an open-label, cohort study. The study enrolled all patients who were clinical diagnosed as BPH with LUTS and prepared to receive operation of the prostate at the Department of Urology of the Second Hospital of Hebei Medical University. International Prostate Symptom Score (IPSS) were used to evaluate the LUTS of the BPH. And the enrolled patients were divided into four groups, including none, mild HI, moderate HI, and severe HI, based on postoperative pathological results. Then the relationships between HI and IPSS, the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), as well as PSEP were analyzed. Simple and multiple linear regression analyses were performed on the preoperative IPSS and the difference of IPSS before and after surgery was examined. SPSS software version 26 was used for statistical analysis and Prism 9.0 was used to make violin plots. A total of 69 patients were enrolled in the study. The violin plot results indicated IPSS and NIH-CPSI scores exhibited significant increases in correlation with the severity levels of HI (P<0.001; P<0.001). Among BPH patients with total prostate-specific antigen (t-PSA) levels higher than 4.0 ng/mL, a significant correlation was observed between PSEP levels and HI (P=0.04). Besides, simple and multiple linear regression analysis showed that HI (P<0.001) or PSEP (P=0.03) was significantly associated with IPSS and improvement of LUTS, assessed by postoperative and preoperative IPSS differences. The study indicated that IPSS and PSEP (when t-PSA >4 ng/mL) were correlated with the severity of HI in patients with BPH. PSEP was linearly correlated with IPSS and the degree of reduction in IPSS after surgery. Consequently, PSEP may serve as a promising predictor for assessing surgical efficacy and diagnosing the severity of HI in patients with BPH.

PENGARUH KUALITAS PELAYANAN TERHADAP REPURCHASE INTENTION PADA E - COMMERCE

This research aims to analyze the influence of service quality on repurchase intention in e-commerce. This research uses a quantitative approach with a survey method involving 220 respondents who have actively shopped on e-commerce in the last six months. The data collection instrument is a questionnaire whose validity and reliability results have been tested. The results of simple linear regression analysis show that all dimensions of service quality have a positive and significant influence on repurchase intention and 63% of service quality influences repurchase intention in e-commerce. Improving service quality can not only attract new customers but is also very important to retain customers. existing ones, which can ultimately improve overall business performance

Examining the Prospects of Residential Water Demand Management Policy Regulations in Ethiopia: Implications for Sustainable Water Resource Management

This study examines the prospects of residential water demand management policy regulations in Ethiopia and their implications for sustainable water resource management. This study aims to evaluate the existing policy regulations and analyze their effectiveness in promoting efficient water use and conservation practices in residential areas. By considering the potential challenges and opportunities associated with these regulations, the research provides insights into the future of residential water demand management in Ethiopia and suggests strategies for enhancing sustainable water resource management. An integrated literature and policy document review, alongside observation and interviews, was used to assess the viability of residential water demand management policies. The assessment of current policy regulations for residential water demand management in Ethiopian urban towns has revealed significant shortcomings in promoting water conservation activities. Simple linear regression analysis of water consumption data from 2010 to 2020 showed no significant reduction in water usage, with an increase in average consumption from 43, 39, and 28 L per capita per day (LPCD) pre-policy to 72, 51, and 42 LPCD post-policy for Arba Minch, Ziway, and Debre Birhan, respectively. Hence, there is a need for significant improvements in the current water resource policy guidelines, which lack specificity, particularly in residential water demand management conservation strategies. The lack of awareness among residents regarding the importance of conserving their limited water resources is evident. To address these challenges and ensure the sustainability of the water supply, the government and policy developers must engage with various stakeholders, including the community, in the process of revising current policy documents. A more precise and tailored approach is necessary for its effective implementation.

Pengaruh Harga Pokok Produksi (HPP) terhadap Laba Bersih Pabrik Minyak Goreng Kemasan Tahun 2022-2023

The research aims to determine the effect of production costs on net profit. This study was carried out by considering fluctuations in production costs as well as increases and decreases in net profit for the period 2022 to 2023 This research is quantitative research. The population of this research consists of all financial reports of PT. Permata Hijau Palm Oleo Belawan and this research is financial reports for a year from 2022 to 2023. The data source for this research is secondary data. The processed with SPSS verion 25 software. The results of simple linear regression analysis show Y = -72454.130 + 0.868X. Meanwhile, the results of the of the t test show that production costs partially have a positive and signigicant effect on the net profit of the PT. Permata Hijau Palm Oleo Belawan. This is proven by tcount 6,786 &gt; ttable 1,71387. This means that H0 is rejected and Ha is accepted. The coefficient of determination test (R2) was 67,7% dan 32,3% respectively, but was influenced by other factors not discussed in this study.

An ANALYSIS OF CONTRACTOR PERFORMANCE FOR ROAD REHABILITATION WORK USING SPECIAL ALLOCATION FUND OF 2022 IN MALANG REGENCY

Road is one of basic infrastructure playing crucial role in development process. Good condition of road creates properes transportation system. It, in turns ensures smooth movement of men and goods. Good transportation will make price of public goods cheap. So far, road rehabilitation works in Malang regency are conducted by usin Special Allocation Fund raising severeal problems such as late down payment, material queue and other. This study aims at analysisng performance of contractor of road rehabiitation using Special Allocation Fund of 2022 in Malang Regency. Customer Satisfaction Index analysis is used to analyse the contractors performance. In addition, Importance Performance Analysis is employed to find out performance variabel that should be improved or maintained. Then, simple linear regression analysis is used to find out the correlation between stakeholders’ level of satisfaction and performance importance on the part of contractors of road rehabilitation works using Special Allocation Fund of 2022 in Malang Regency. The findings shows that stakehoders are higly satisfied with performance of contractors of road rehabilitation works using Special Allocation Fund of 2022 in Malang Regency. It is shown by score of CSI 86,99%. It is also found that there is positive and significant correlation between stakeholders’ level of satisfaction and performance importance on the part of contractors of road rehabilitation works using Special Allocation Fund of 2022 in Malang Regency. However, there are some performance variables that should be improved by the contractors.

Affiliate Stigma, Resilience and Quality of Life among Parents of Children with Autism Spectrum Disorder in Two Public Hospitals in Kelantan, Malaysia.

Often, the indirect impact of autism spectrum disorder (ASD) presents the family with significant challenges. One of these challenges is affiliate stigma due to parental affiliation with their child. This study aimed to explore affiliate stigma, resilience and quality of life (QoL) among parents of children with ASD. Cross-sectional study of 144 parents of children with ASD were recruited from two main tertiary hospitals in Kelantan, Malaysia, a developing country in Southeast Asia. Pearson correlation was used to examine the relationship between parental affiliate stigma, resilience and QoL. Simple and multiple linear regression analyses were used to identify the significant associated factors of affiliate stigma, resilience and QoL. Correlational analyses revealed that perceived affiliate stigma demonstrated an inverse relationship with resilience and QoL. Additionally, resilience had a positive relationship with QoL. Regression analyses revealed that the father's employment status, the mother's level of education, having a disability card, the child's age at ASD diagnosis, comorbidities of the child and ASD severity perceived by parents were associated with parental affiliate stigma, resilience and QoL. Study findings highlight the contribution of socio-demographic characteristics of children with ASD and their families in the determination of affiliate stigma, resilience and QoL.

Pengaruh Citra Destinasi Dan Electronic Word Of Mouth (E-WOM) Terhadap Minat Kunjung Wisatawan Di Simpang Lima Gumul Kediri

This research aims to determine the influence of destination image and electronic word of mouth (E-WOM) on tourist interest in visiting the Simpang Lima Gumul Kediri Monument. This research uses quantitative methods with descriptive analysis. The sample taken was 100 respondents and the sampling technique used an approach to simple random sampling. Data analysis in this study used simple linear regression analysis, multiple linear regression analysis, classic assumption test, T test, F test, and coefficient of determination test. The results of the research show that there is a positive and significant influence with a coefficient value of 0,299 on destination image on interest in visiting, there is a positive and significant influence with a coefficient value of 0,555 on electronic word of mouth (E-WOM) on interest in visiting, and there is simultaneous influence of 70,3% on destination destination image and electronic word of mouth (E-WOM) on touris interest in visiting the Simpang Lima Gumul Kediri Monument.

The Role of Ethical Leadership in Enhancing Employees’ Job Immersion / Case Study (Ministry of Construction, Housing and Public Municipalities)

The research aims to shed light on ethical leadership as an independent variable represented by its dimensions (justice, participation in power, role clarity, concern for employees, integrity, and moral guidance) and its role in enhancing job Immersion among the employees of the Ministry of Construction and Housing and public municipalities in Iraq as a dependent variable represented by Its dimensions (activity, dedication, and involvement). The research used the descriptive analytical method, and the survey was used as a research tool. The surveys were distributed to all members of the sample through the use of a comprehensive inventory method, totaling (118) individuals at different administrative levels of the above-mentioned ministry. Statistical packages (spss.v26) and statistical methods, including (descriptive statistics scale, Pearson correlation coefficient, and simple linear regression analysis) were used to analyze the data with the aim of answering the research questions. The most important of which is the main research question (Is there an awareness among the management of the sample studied when it follows the ethical leadership style and the level of its influence on the job Immersion of its employees). Through the results of data analysis, the research concluded that ethical leadership has a positive relationship and impact on job Immersion in the Iraqi Ministry of Construction and Housing and public municipalities, as the two main hypotheses of the research were achieved

Pengaruh Gaya Kepemimpinan dan Disiplin Kerja terhadap Kinerja Karyawan pada PT. Matra Adhiraya Nusantara Jakarta Barat

The aim of this research is to determine the influence of Leadership Style and Work Discipline on employee performance at PT Matra Adhiraya Nusantara West Jakarta. The research method used is a quantitative method. The data collection techniques in this research include distributing questionnaires to all employees and the data analysis techniques used in this research are validity test, reliability test, classical assumption test, descriptive analysis, simple linear regression analysis, multiple linear regression analysis and partial hypothesis testing ( t) and simultaneous (F). The results of the research show that leadership style and work discipline influence employee performance with a regression equation of Y = 2.020 + 0.618 X1 + 0.339 &gt; t table or 7.239&gt;1.993 then Ho1 is rejected and Ha1 is accepted. Partially, Work Discipline influences employee performance with the results of the t test &gt; t table or 4.098&gt; 1.993, so Ho2 is rejected and Ha2 is accepted. The results of simultaneous hypothesis testing show that the calculated f value is &gt; f table or 166.099 &gt; 3.120, so Ho3 is rejected and Ha3 is accepted. It can be concluded that the research results show that Leadership Style and Work Discipline influence employee performance at PT Matra Adhiraya Nusantara, West Jakarta.

Assessing the Financial Literacy of Madrasah Principals in Formulating Revenue and Expenditure Budget Plans

This research aims to analyze and understand the level of financial literacy of Madrasah Principals in preparing the Madrasah Revenue and Expenditure Budget Plan (RAPBM) in Raudlatul Athfal (RA) Pasuruan Regency, East Java. The formulation of the problem in this research is whether there is an influence on the financial literacy of Madrasah Principals in preparing the Madrasah Revenue and Expenditure Budget Plan (RAPBM). This research uses a quantitative approach. The data source comes from Madrasah Principals. With data collection techniques through questionnaires and documentation. Then tested with simple linear regression analysis. The results found the regression coefficient value of 0.18 (positive), the correlation value was 0.029, the R square value was 0.116 (11.6%), and the significance value was 0.029 0.05, meaning that there was an effect of the financial literacy level of the Madrasah Principals in develop a Madrasah Revenue and Expenditure Budget Plan (RAPBM) in Raudlatul Athfal (RA) of East Java Pasuruan Regency. Thus, the better financial literacy, the better the preparation of the RAPBM.

The Influence of Students Perceptions of Outdoor Study Methods on Students Learning Motivation in Social Studies

The purpose of this study was to determine the effect of student perceptions about the use of outdoor study methods on student learning motivation in social studies learning in Probolinggo District. Outdoor study has urgency in improving students' capabilities in both physical and non-physical aspects. This study used a correlational method using a questionnaire as an instrument. The population in this study included all junior high school and MT students in Probolinggo Regency. Purposive sampling was the sampling technique in this study. The sample totaled 91 students: 42 students from SMPIT Permata Kraksaan, 30 students from MTs Al-Husna, and 19 students from SMPN 4 Kraksaan. This study used simple linear regression analysis to analyze the data. The results indicated that students' perceptions of the use of outdoor study methods contributed 45.4% to students' learning motivation, and a total of 54.6% was affected by components that were not the focus of discussion in this study. While the correlation level is 0.674, this is a strong category. In the results of the t test or partial, student perceptions about the use of outdoor study methods have a positive or significant effect on student learning motivation. The value of 8.598&gt; 1.666 and the sign value of 0.000 &lt;0.005 mean that H0 is rejected and Ha is accepted, or student perceptions about the use of outdoor study methods affect student learning motivation.

Analisis Pengaruh Game Online Terhadap Perilaku Siswa SD Negeri 3 Petungsinarang Bandar

This study investigated how online games affect student behavior in SD Negeri 3 Petungsinarang, Bandar District, Pacitan Regency, East Java. This research was conducted through survey method. This study involved all students in grades IV, V, and VI of SD Negeri 3 Petungsinarang Bandar. In total, 26 students from grades IV, V, and VI of SD Negeri 3 Petungsinarang Bandar were taken as samples, and a simple random sample method was used. The instrument is a questionnaire with a rating scale and Likert scale. Questionnaires are used to collect data. Simple linear regression analysis is used to present the data. The results showed that the value of fcount (2.471) was greater than ftable (0.388252), and the significant level of α = significant regression of 0.05. Therefore, the test results resulted in a regression equation Y = 39,120 + 0.249, which shows that online games affect student behavior in grades IV, V, and VI of SD Negeri 3 Petungsinarang Bandar District. The constant 39.120 indicates that if the value of the online game is 0, then the student's behavioral value (Y) is equal to 39.120. The positive relationship between the online game variable (X) and the student behavior variable (Y) is indicated by a positive value The higher the student's score in an online game is characterized by the lower the student's interest in the game, and vice versa. The higher the score, the better the student's behavior.

Association between glycated hemoglobin index and triglycerides-glucose index in a sample of non-diabetic individuals and its relation with insulin resistance

Introduction: Studies have shown that elevations of the triglyceride/glucose index (TyG) as well as the glycation of hemoglobin index (HGI) are associated with several complications related to insulin resistance (IR). Objective: To evaluate the association between HGI and TyG index in a sample of non-diabetic individuals and it’s relation with IR. Method: A cross-sectional study was conducted with 32 non-diabetic individuals. The variables analyzed included age, gender, body mass index, and laboratory data (triglycerides, glucose, HbA1c, and insulin). We calculated the TyG index, HOMA-IR, and HGI. Simple and multivariate linear regression analyses were also performed, in addition to ANOVA and Pearson's correlation between variables. Results: The multivariate linear regression analysis of the analyzed sample revealed a significant correlation between the TyG index and HGI, which was confirmed by the T-test. The results indicated a strong positive correlation between the TyG index and HGI, with a Pearson correlation coefficient of 0.98. Conclusion: The HGI, TyG index and IR showed a significant association in the analyzed sample. This suggests that both indices are highly reliable in measuring IR and glucose metabolism and may be markers of risk independent of fasting plasma glucose, and the other variables evaluated in this study.

The frequency of sepsis-associated delirium in intensive care unit and its effect on nurse workload.

To determine the frequency of sepsis-associated delirium (SAD) in the intensive care unit and its effect on nurse workload. A cross-sectional and correlational design was used. The study was conducted with 158 patients in the adult intensive care unit of a hospital between October 28 and July 28, 2022. Data analysis included frequency, chi-squared/fisher's exact test, independent samples t-test, correlation analysis, simple and multiple linear regression analyses. The study adhered to the STROBE guidelines. Sepsis was detected in 12.7% of the patients, delirium in 39.9%, and SAD in 10.1%. SAD was more common in males (19%) and 56.3% of the patients were admitted to the unit from the emergency department. Patients developing SAD had significantly higher age and mean sequential organ failure evaluation, acute physiology and chronic health evaluation II, and C-reactive protein and lactate scores, but their Glasgow Coma Scale scores were significantly low. There was a moderate positive relationship between the patients' Sequential Organ Failure Assessment score and the presence of SAD. The most common source of infection in patients diagnosed with SAD was bloodstream infection (44.4%). SAD significantly increased nurse workload and average care time (1.8 h) and it explained 22.8% of the total variance in nurse workload. Additionally, the use of antibiotics, vasopressors and invasive mechanical ventilation significantly increased nurse workload. In the study, in patients who developed SAD increased nurse workload and average care time significantly. Preventive nursing approaches and effective management of SAD can reduce the rate of development of SAD and nurse workload. It is important to work with routine screening, prevention and patient-nurse ratio appropriate to the workload for SAD.

Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum

Drug discovery is an intricate and costly process. Repurposing existing drugs and active compounds offers a viable pathway to develop new therapies for various diseases. By leveraging publicly available biomedical information, it is possible to predict compounds’ activity and identify their potential targets across diverse organisms. In this study, we aimed to assess the antiplasmodial activity of compounds from the Repurposing, Focused Rescue, and Accelerated Medchem (ReFRAME) library using in vitro and bioinformatics approaches. We assessed the in vitro antiplasmodial activity of the compounds using blood-stage and liver-stage drug susceptibility assays. We used protein sequences of known targets of the ReFRAME compounds with high antiplasmodial activity (EC50 < 10 uM) to conduct a protein-pairwise search to identify similar Plasmodium falciparum 3D7 proteins (from PlasmoDB) using NCBI protein BLAST. We further assessed the association between the compounds' in vitro antiplasmodial activity and level of similarity between their known and predicted P. falciparum target proteins using simple linear regression analyses. BLAST analyses revealed 735 P. falciparum proteins that were similar to the 226 known protein targets associated with the ReFRAME compounds. Antiplasmodial activity of the compounds was positively associated with the degree of similarity between the compounds’ known targets and predicted P. falciparum protein targets (percentage identity, E value, and bit score), the number of the predicted P. falciparum targets, and their respective mutagenesis index and fitness scores (R2 between 0.066 and 0.92, P < 0.05). Compounds predicted to target essential P. falciparum proteins or those with a druggability index of 1 showed the highest antiplasmodial activity.

Pengaruh Kualitas Pelayanan Penggunaan Aplikasi Pospay Terhadap Loyalitas Pelanggan Studi KAsus PT. Pos Indonesia (Persero) Kantor Pos Cabang Probolinggo

Businesses want to be aware of customer needs and desires in order to fulfill client expectations. Every consumer views the services they receive and their level of satisfaction varies, as does the Pospay application, a digital service application that is controlled by PT. Pos Indonesia. The purpose of this study is to evaluate the PosPay application's quality. services in the city of Probolinggo. Quantitative research methodology was employed in this investigation. Information in this research was collected by distributing questionnaires. The population and sample contained in this study, namely customers who use the pospay application in Probolinggo City, were sampled as many as 30 people. The sampling method uses saturated samples. Simple linear regression analysis is the data analysis method employed. The result showed that respondents responses to the quality of Pospay services at PT. Pos Indonesia (persero) Probolinggo City Branch, showed that respondents gave (positive) responses where the quality of the respondents physical evidence indicator was 0,588, norma residual was 0,030, reability was 0,770. This proves that the quality of Pospay services in the Probolinggo City Branch of PT. POS INDONESIA (persero). is good. Regarding respondents assessment of the quality of Pospay services at PT.Pos Indonesia Branch which is expected with the services received shows that respondents give respondents according to the expectation of the dimensions of 0.05

Parental Involvement and Classroom Climate as Predictors of Metacognitive Skills in English Subjects among Junior High School Students

This study aimed to investigate whether parental involvement and classroom climate significantly predict metacognitive skills among junior high school students in public secondary institutions in Davao City, Philippines. Employing a descriptive-correlational research design, standardized questionnaires were administered through face-to-face surveys to 200 junior high school students The mean, standard deviation (SD), Pearson product-moment correlation, as well as simple and multiple linear regression analyses were utilized for data analysis. The findings revealed that the extent of parental involvement, classroom climate, and metacognitive skills were described as extensive. Correlation analysis indicated significant relationships between parental involvement, classroom climate, and metacognitive skills. Furthermore, parental involvement and classroom climate significantly influenced the metacognitive skills of junior high school students. It is recommended that educators and policymakers prioritize initiatives to enhance parental involvement and foster positive classroom climates. Additionally, interventions aimed at improving metacognitive skills may be integrated into educational programs.

Academic Motivation and Cognitive Abilities as Predictors of English Language Proficiency among Senior High School Students

This study aimed to determine whether academic motivation and cognitive abilities significantly predict English language proficiency among senior high school students in a public secondary institution in Davao City, Philippines. Employing a descriptive-correlational research design, standardized questionnaires were administered through face-to-face surveys to 209 students. The mean, standard deviation (SD), Pearson product-moment correlation, as well as simple and multiple linear regression analyses were utilized for data analysis. The findings revealed that while the academic motivation of the students was described as extensive, their cognitive abilities and English language proficiency were described as moderately extensive. Correlation analysis indicated significant relationships between academic motivation, cognitive abilities, and English language proficiency. Furthermore, there is a significant combined influence of academic motivation and cognitive abilities on English language proficiency among senior high school students. It is recommended to focus on enhancing both academic motivation and cognitive skills to improve English language proficiency further. Collaborative interventions targeting these areas can effectively support students in achieving greater proficiency in English.

Pengaruh Social Comparison Terhadap Fear of Missing Out Pada Mahasiswa di Universitas Negeri Padang

This research aims to determine the effect of social comparison on the fear of missing out among students at Padang State University. This research uses quantitative methods with a correlational quantitative design. The data collection technique uses cluster sampling. The data collection technique uses a questionnaire with a Likert scale model which is distributed with the help of the Google Form feature. The sample for this research was 188 respondents. The research instrument used Kurniawan &amp; Utami's (2022) fear of missing out scale which was adapted from (Sette et al., 2020), as well as a social comparison scale based on aspects of Buunk et al., (2003). The results of the research used simple linear regression analysis and the results showed that social comparison had a positive and significant effect on fear of missing out in students at Padang State University.

Quantifying the natural growth rate of hepatocellular carcinoma: A real-world retrospective study in southwestern China.

In recent years, approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma (HCC) have been reported in China. Despite the high incidence of HCC, there remains a paucity of data regarding the natural growth pattern and the determination of optimal surveillance intervals specific to the Chinese population. To quantify the natural tumor growth pattern of HCC in regional China. A retrospective analysis was performed on patients from a single institution in Southwest China who had undergone two or more serial dynamic computed tomography or magnetic resonance imaging scans between 2014 and 2020, without having received any anti-cancer therapy. Tumor growth was assessed using tumor volume doubling time (TVDT) and tumor growth rate (TGR), with volumes measured manually by experienced radiologists. Simple univariate linear regression and descriptive analysis were applied to explore associations between growth rates and clinical factors. This study identifies the median TVDT for HCC as 163.4 d, interquartile range (IQR) 72.1 to 302.3 d, with a daily TGR of 0.42% (IQR 0.206%-0.97%). HCC growth patterns reveal that about one-third of tumors grow indolently with TVDT exceeding 270 d, another one-third of tumors exhibit rapid growth with TVDT under 90 d, and the remaining tumors show intermediate growth rates, with TVDT ranging between 3 to 9 months. The identified TGRs support biannual surveillance and follow-up for HCC patients in certain regions of China. Given the observed heterogeneity in HCC growth, further investigation is warranted.