Simple Exposure Research Articles

Glaciovolcanic processes between the Campbell Glacier and Mt. Melbourne Volcano, Antarctica: ICE and FIRE

This study investigates the glacial dynamics of the Campbell Glacier in Terra Nova Bay (TNB), Antarctica, with a focus on its unique lowering patterns during the late Quaternary. Using cosmogenic nuclides (10Be) surface exposure dating, we provide significant chronological constraints on Antarctic terrestrial glacier changes. In addition to the previous data on Marine Isotope Stage (MIS) 5 simple exposure ages of Campbell Glacier moraines, we further analyzed the palaeo-subglaciated bedrock, which yields exposure ages during MIS 3 and 2 (49.8–28.5 ka). Our analysis empowers that continuous glacial lowering occurred throughout the late Quaternary, even during the Last Glacial Period (MIS 4–2), and that the Local Last Glacial Maximum (LLGM) occurred at 150–90 masl during MIS 4 rather than MIS 2. This new and recalculated dataset for the Campbell Glacier is unique compared to other outlet glaciers flowing into the Terra Nova Bay, highlighting the significant influence of Mt. Melbourne's volcanic activity via glaciovolcanic processes during the late Quaternary, beyond general climatic and oceanic factors. Further studies of palaeo-glaciovolcanic interactions on the East Antarctic Ice Sheet (EAIS) promise to provide more robust insights for refining models predicting future accelerated glacial melt and sea level rise, particularly considering the numerous volcanoes beneath the West Antarctic Ice Sheet (WAIS).

Enzymatic Glycosylation of 4'-Hydroxychalcones: Expanding the Scope of Nature's Catalytic Potential.

Chalcones, including 4'-hydroxychalcones, have garnered significant attention in the area of drug discovery due to their diverse pharmacological properties, such as anti-inflammatory, antioxidative, and anticancer effects. However, their low water solubility and bioavailability limit their efficacy in vivo. Glycosylation presents a promising approach to enhance the water solubility, stability, and metabolic properties of chalcones. This study investigates the enzymatic glycosylation of eight chemically synthesized 4'-hydroxychalcones using a diverse set of sugar glucosyltransferases from bacterial, plant, and fungal sources, alongside Glycine max sucrose synthase (GmSuSy) in a cascade reaction. Among the tested enzymes, five exhibited a remarkable versatility for glycoside production, and for large-scale biotransformation, flavonoid 7-O-glucosyltransferase Sbaic7OGT from Scutellaria baicalensis was selected as the most effective. As a result of the experiments conducted, eight trans-chalcone glycosides were obtained. During the purification of the reaction products, we also observed the isomerization of the products by simple sunlight exposure, which resulted in eight additional cis-chalcone glycosides. This study highlights the novel use of a cascade reaction involving Glycine max sucrose synthase (GmSuSy) for the efficient glycosylation of trans-4'-hydroxychalcones, alongside the unexpected discovery of cis-chalcone glycosides during the purification process.

Explaining Protest Participation in Semi-authoritarian Regimes: The Power of Social Networks

AbstractThis study uses the case of ecological protests in the Russian Federation and the social network of 903 263 VKontakte users to investigate the unique characteristics of protesters’ social networks and assess the effects of network topology on the likelihood of participation. By applying Bayesian structural equation modeling to the data, the study finds that social network topology plays a more nuanced and complex role in predicting protest participation beyond simple exposure to information. Notably, individuals situated as brokers in lower-density and higher-closure networks exhibit a higher likelihood of participation, while central nodes participate less. The results highlight the importance of strategic positioning as brokers for increasing the likelihood of participation. The paper discusses these and other findings, contributing to a deeper understanding of the interplay between social network structures and protest participation.

Let’s Talk About Condoms: Social Engagement in a Sexual Health Intervention Targeting Young Adults in Denmark

Objectives We tested whether social activities and interactions as part of a condom campaign strengthened young adults’ condom-use intentions and normative perceptions of condoms compared to simple exposure to campaign information. Method Data from 3,041 young adults collected after four annual condom campaigns were analyzed and combined into a meta-analysis. Results Interaction about the campaign and engagement in campaign-related activities was associated with higher condom use intention and more positive pro-condom norms. Conclusions The authors call for a greater emphasis on social influence in youth-aimed sexual health campaigns. Implications for the research are discussed.

Mapping the extent of unhealthy food advertising around schools in Tāmaki Makaurau/Auckland

ABSTRACT Advertisements promoting energy-dense, nutrient-poor food and drinks influence children’s dietary choice and preference and are pervasive in children’s environments across Aotearoa, New Zealand. Using a combination of datasets from separate studies, this research seeks to describe the extent of children’s unhealthy food/drink advertising exposure in all primary and intermediate school food zones (n = 381) in Tāmaki Makaurau, Auckland, and assess whether this exposure correlates with indicators of neighbourhood deprivation. To achieve this, we developed a simple advertising exposure score using images of advertising collected from Google Street View, and investigated its spatial correlation with indicators of neighbourhood deprivation. Outdoor advertising was present in proximity to 61.9% of the sampled schools (n = 236); of which 83.1% of adverts promoted unhealthy food and/or drinks (n = 2669). Advertising exposure increased statistically significantly with neighbourhood deprivation (p < 0.05). The results show a clear need for policy intervention that regulates and limits unhealthy food/drink advertising around schools in New Zealand. The advertising score proved a useful, easy to understand tool to measure and visualise children’s potential exposure to unhealthy food/drink advertising. The score may be used to increase community awareness of the ubiquity of unhealthy advertising in children’s neighbourhoods and advocate for policy change. Practitioner points Advertising present in the vicinity of 62% of Auckland schools; 83% of adverts promoted unhealthy food and/or drinks Novel advertising score assesses the spatial distribution of unhealthy advertising exposure. Advertising exposure score is significantly related to neighbourhood deprivation. Findings show the need for policy action to limit children’s advertising exposure around their schools in NZ.

Can Salvinia auriculata bioremediate the toxic effects of Fipronil 800wg on the tadpoles of Dendropsophus minutus?

Worldwide, the indiscriminate and escalating application of pesticides has led to extensive impacts on both the environment and non-target organisms. Phytoremediation, which employs plants to decontaminate environments, is a potential strategy for the mitigation of this damage. The present study assessed the phytoremedial potential of Salvinia auriculata, an aquatic macrophyte known to be effective for the removal of environmental contaminants. In the laboratory, Dendropsophus minutus tadpoles were exposed to different concentrations (0.035, 0.1, 1.0, and 1.5 mg/l) of the commercial insecticide Fipronil 800wg in two treatments – (i) simple exposure for 96 h, and (ii) exposure for 168 h in aquariums containing S. auriculata. In the first experiment, a mortality rate of 33.3 % was recorded at the highest Fipronil concentration (1.5 mg/l), and genotoxic parameters increased at all concentrations except 0.035 mg/L, in comparison with the control. In the second experiment, phytoremediation occurred at all the concentrations tested, with lower frequencies of cells with micronuclei, and binucleated, anucleated, and pyknotic nuclei being observed, in comparison with the first experiment. These findings highlight the potential effectiveness of S. auriculata for the phytoremediation of environments contaminated by pesticides and contribute to the understanding of the benefits of this approach for the protection and preservation of aquatic biodiversity.

Using Irradiation-Acquisition Interleaved Time-Integrated Imaging to Assess Delayed Luminescence and the Noise-Laden Residual Spontaneous Photon Emission of Yeast

Delayed luminescence from organisms informs oxidative stress that may be modulable by external stimulations. In the absence of external stress causing delayed luminescence, organisms may produce spontaneous ultraweak photon emission due to the residual oxygen demand. To better understand the oxidative state of an organism, it is desirable to acquire the delayed luminescence to reach the phase wherein the ultraweak photon emission resides. This, however, is challenging due to the significant difference in the order of magnitude of the photon counts between the two types of photon emission. Conventional time-gated measurement requires a high dynamic range to assess the noise-level photon emission, whereas simple long exposure can miss the kinetics of luminescence. There may be a compromise to be made between robustly acquiring the decay kinetics of the delayed luminescence and reliably acquiring the noise-laden spontaneous photon emission. We demonstrate an irradiation-acquisition interleaved time-integrated imaging approach that may enable the reliable acquisition of slow-decay delayed luminescence down to the level of ultraweak photon emission. Repetitive irradiation was interleaved with a gradually increased time of acquisition to assess the integrated time course of the post-irradiation luminescence. Such instrument configuration performed on yeast facilitated the use of time differentiation to assess the delayed luminescence down to the noise-level ultraweak photon emission at the expense of the total time of acquisition.

Latent inhibition in humans from simple stimulus exposure.

Two experiments observed an effect consistent with a latent-inhibition (LI) effect in humans that (a) did not depend on masking or instruction-generated expectations and (b) suggested that the effect results from a change in processing of the predictive cue. Participants viewed a video of a superhero character flying through three different contexts past a different stimulus in each context. In conditioning, The superhero flew past a target cue that was either Novel (Group No Exposure), had been preexposed in the Same context as where conditioning was occurring (Group Same), or was preexposed in a Different context (Group Different). Each time the superhero flew past the target cue his Hands Glowed (outcome). On test (E1), an image of the superhero flying in the context with normal Hands and the target cue was present. Participants were asked if anything was missing. Experiment 2 tested participants with the superhero present and his Hands Glowing to test outcome-cue associations (Test 1) or just the superhero in the context (Test 2, counterbalanced) to assess contextual associations. In E1 fewer people in Group Same reported the outcome missing than Group No Exposure or Group Different. In E2 fewer people in Group Same reported the target cue missing when presented with the outcome than in the other groups, a result inconsistent with interference accounts of LI. When presented only with contextual cues, reports of the stimulus missing showed that the context was associated with the stimuli presented within it. Results are discussed with respect to theories and demonstrations of human LI. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Assessment of clinical relevance of antigen improves diagnostic accuracy of hypersensitivity pneumonitis

BackgroundExposure assessment is integral to the diagnosis of hypersensitivity pneumonitis (HP). Although the clinical relevance of exposed antigens is essential for the assessment, many of the previous guidelines or reports have only evaluated simple exposure histories or immunological tests. To overcome this problem, the Exposure Assessment Form (EAF) was developed as an assessment tool for classifying the exposure grade from G0 to G4. The EAF was modified from the description in the Japanese clinical practice guide 2022 for HP published by the Japanese Respiratory Society.MethodsOne hundred and seventy-two consecutive patients with interstitial lung disease who underwent multidisciplinary discussion (MDD) at our hospital were retrospectively examined. We assessed whether the use of the EAF improved the diagnostic performance of the international guideline of HP. We also evaluated whether the exposure grade affected the prognosis of HP.ResultsEven when a HP diagnosis was made with a confidence of 70% or higher according to the international guideline, less than half of these cases resulted in a final diagnosis of HP when the exposure grades were lower than G3. When the result of the EAF was integrated into the exposure definition of the international guideline, the specificity of the diagnostic performance improved, while sensitivity was maintained. Furthermore, HP patients with an exposure grade of G3 or higher showed a tendency to take a longer time to initiate medication.ConclusionsThis is the first study to evaluate the clinical relevance of possible antigens using the EAF. Assessing the exposure grade prevents overdiagnosis and improves the diagnostic performance of the international guideline.

Microfluidic-organic thin film transistor coupled platform for simple solution exposure

Organic thin film transistors (OTFTs) have been combined with microfluidic in a non distructive process, enabling the simple exposure of the oragnic semicondcutor to different analytes.

Synthesis and investigation; influence of Mn doping on biological, optical, dielectric and electrochemical characteristics of Bi2O4 nanostructures

In this research, bismuth oxide thin films were synthesized with the variation of Mn dopant (1-5 wt %) on a glass slide by sol-gel dip coating method. XRD corroborated the creation of a monoclinic phase for all the samples after annealing at 450 °C for 4 h. The non-uniform cuboid-like granular structures were observed by SEM with a significant number of grain boundaries. Different functional groups were examined by using FTIR spectroscopy. The optical band gap was reduced from 2.01 to 1.81eV by increasing the concentration of Mn dopant. The contribution of grain and grain boundaries to the material electrical response in various frequency ranges was distinguished by impedance analysis. The polaron mechanism was used to investigate conductivity with time variation. The efficiency of supercapacitors was significantly enhanced by using the monoclinic Bi2O4 phase of bismuth oxides, promoting the specific capacitance in the range of 2518.2–6890.2 Fg-1 with high energy and power density. That leads them to the fabrication of supercapacitors in advanced electronic devices. Magnetic analysis showed that saturation magnetization and remanent frequency decreased while coercivity of thin films increased with increasing Mn concentration which was successfully explained by the critical size effect and Néel's collinear two sub-lattice models, making them plausible candidates in spintronics. As from photocatalyst analysis, the number of reactive oxygen species ROS was increased by increasing Mn doping in the Bi2O4 crystal lattice. These species degraded the water pollutants under simple exposure to sunlight (i-e visible range). The production of ROS in the photocatalytic process was also correlated with antibacterial activity. Mn-doped Bi2O4 was found to be more effective towards K. pneumonia than other bacteria. The prepared Mn:Bi2O4 nanostructures with a higher percentage of manganese were effectively used for the treatment of bloodstream infections, meningitis, pneumonia, and urinary tract infections and stopped further bacterial growth.

How exposure to patient narratives affects stereotyped choices of primary care clinicians.

In this paper, we examine whether patient narratives alter the impact of stereotyping on choice of primary care clinicians: in this case, the common presumption that female doctors will be more attentive to empathic relationships with patients. 1052 individuals were selected from a nationally representative Internet panel to participate in a survey experiment. Participants were given performance data about 12 fictitious primary care physicians, including a randomized set of narrative feedback from patients. We compared the choice of clinician made by participants who value bedside manner and were exposed to narratives in the experiment, compared to those valuing bedside manner who had not had this exposure. We estimated multivariate logistic regressions to assess whether exposure to patient comments that "disrupt" stereotypes influenced choice of physicians. Participants who saw patient comments and had previously reported caring about bedside manner had a 67% higher odds of choosing a female physician than those participants that did not see a patient comments, controlling for the content of the narratives themselves. When participants were exposed to patient comments that disrupt gendered stereotypes, they had a 40% lower odds of choosing a female physician. Simple exposure to patient narratives that do not clearly disrupt gendered stereotypes increased the likelihood of choosing a female clinician by priming attention to relational aspects of care. However, when the content of a sufficient proportion of patient comments runs counter stereotypes, even a minority of narratives is sufficient to disrupt gendered-expectations and alter choices.

Vapor-phase postsynthetic amination of hypercrosslinked polymers for efficient iodine capture

Hypercrosslinked polymers (HCPs) with large surface areas, high intrinsic porosities and low production costs may be available platforms for iodine capture. However, the lack of iodine-philicity binding sites limits their adsorption capacity. Here we use vapor-phase postsynthetic amination strategy to introduce electron-donating amino groups into the prefabricated HCPs for enhancing their iodine capture performance. Through simple vapor-phase exposure, the halogen-containing HCPs can be grafted by amines through nucleophilic substitution toward chloro groups. Combining with the abundant amino groups and high porosities, the amino-functionalized porous polymers show substantially increased iodine adsorption capacity, about 221% as that of original one, accompanied by excellent recyclability. Mechanism investigations reveal the key roles of the electron-donor amino groups and π-conjugated benzene rings along with structure characteristics of porous polymer frameworks in iodine capture. Moreover, this vapor-phase amination strategy shows good generality and can be extended to various amines, e.g., ethylenediamine, 1,3-diaminopropane and diethylenetriamine. Our work proves that this simple vapor-phase postsynthetic functionalization strategy may be applied in other porous polymers with wide application prospects in adsorption, separation and storage.

A safe and simple exposure and Pringle maneuver in laparoscopic anatomical liver resection of segment 7

BackgroundLaparoscopic access to liver segment 7 (S7) is difficult for deep surgical situations and bleeding control. Herein, our proposed laparoscopic technique for S7 lesions using a self-designed tube method is introduced.MethodsClinical data of patients who underwent laparoscopic anatomical liver resection of S7 (LALR-S7) with the help of our self-designed tube to improve the exposure of S7 and bleeding control in the Second Affiliated Hospital, Third Military Medical University (Army Medical University) from April 2019 to December 2021 were retrospectively analyzed to evaluate feasibility and safety.ResultsNineteen patients were retrospectively reviewed. The mean age was 51.3 ± 10.3 years; mean operation time, 194.5 ± 22.7 min; median blood loss, 160.0 ml (150.0–205.0 ml); and median length of hospital stay, 8.0 days (7.0–9.0 days). There was no case conversion to open surgery. Postoperative pathology revealed all cases of hepatocellular carcinoma (HCC). Free surgical margins were achieved in all patients. No major postoperative complications were observed. Patients with postoperative complications recovered after conservative treatment. During outpatient follow-up examination, no other abnormality was presented. All patients survived without tumor recurrence.ConclusionsThe preliminary clinical effect of our method was safe, reproducible and effective for LALR-S7. Further research is needed due to some limitations of this study.

국제 게임 유통 플랫폼에 대한 게임물 등급분류 제도의 적용 문제

With the advent of the era when games can be downloaded or played in real time regardless of borders, the importance of international game distribution platforms in the game industry is increasing. However, in the case of Steam, the world's biggest international game distribution platform, it is problematic because it is not properly subject to the domestic game classification system.&#x0D; There are many discussions on the need for improvement in the game classification system, but it is problematic that games that have not been classified are exposed to the public through large international game distribution platforms unless the function of youth protection, which is one of the main purposes of the classification system, is overlooked.&#x0D; In the text, we first look at the history and institutional purpose of the game product classification system, and the rating system overseas, and based on this, we look at the disciplinary system under the current game industry law. Furthermore, it examines how overseas game products are handled in the Game Industry Act, whether the concept definition is appropriate, and how the rating for international game distribution platforms such as Steam should be classified.&#x0D; In conclusion, it is necessary to clarify the concept of overseas game products under the Korean Game Industry Act so that it can be harmonized with the current game classification system. This is because there are already separate autonomous classifications and fines for overseas games, but the establishment of a clear concept category will serve as the basis for systematic regulations and responses to flooding overseas games in the future.&#x0D; In addition, it is necessary to go through close cooperation with major international game distribution platform operators in the future, and gradually proceed with basic discussions such as the introduction of a simple age authentication system and random exposure restrictions on adult games.&#x0D; In particular, since the influx of adult games from international game distribution platforms is not only a problem in Korea, it is also possible to consider cooperating with overseas game rating agencies or organizations. Furthermore, it is necessary to come up with legislative policy measures to properly regulate overseas game products in the long-term direction of improving the game classification system, and in-depth discussions need to be conducted in academia in the future.

Novel participant-level meta-analytic evidence for AbSANT efficacy.

The current study employed interrupted time series (ITS) models to analyze all available (published and unpublished) Abstract Semantic Associative Network Training (AbSANT) data. AbSANT is a semantically focused anomia treatment that targets not only concrete but abstract words, unique among existing anomia treatments. However, evidence to date for the positive effects of AbSANT comes only from small-sample, single-subject design studies, limiting the strength of this evidence and the inferences that can be drawn from it. The statistical power and greater representativeness afforded by this larger aggregated sample enabled us to look for group-level efficacy evidence for AbSANT, examine specific questions about AbSANT's direct training and generalization effects, and identify potential predictors and mechanisms of AbSANT treatment response. We found that across 33 participants from four different data sources, AbSANT appears to be a robust word retrieval therapy protocol, with overall direct training and generalization effects that were more meaningful than exposure effects. Similar to previous smaller-sample study conclusions, we found that in this large sample, training abstract words results not only in larger direct training effects than training concrete words, but also larger generalization effects, suggesting that while AbSANT successfully improves both abstract and concrete word retrieval, it may be better suited for training abstract words. In general, direct training effects were more persistent after treatment ended than generalization effects and effects for concrete words were more persistent than for abstract words. Additionally, the effects of generalization appear to be distinct from the effects of simple exposure to words, and generalization effects are consistent with AbSANT's hypothesized mechanism of action: spreading activation from directly trained concepts to related concepts. Also consistent with this mechanism, we found that milder aphasia and both conceptual and lexical semantic processing ability predicted both direct training and generalization gains, and that executive function was predictive of generalization effects. These factors are thus important to consider when evaluating the appropriateness of AbSANT for individual clients.

From worst-case to reality – Case studies illustrating tiered refinement of consumer exposure to cosmetic ingredients

Consumer exposure to cosmetic ingredients is estimated in a tiered manner. Simple Tier1 deterministic aggregate exposure modelling generates a worst case estimate of exposure. Tier1 assumes that a consumer uses all cosmetic products concomitantly daily, at maximum frequency, and products always contain the ingredient at the maximum allowed % w/w concentration. Refining exposure assessment from worst case to more realistic estimates uses evidence from surveys of actual use levels of ingredients and Tier2 probabilistic models, where distributions of consumer use data can be applied. In Tier2+ modelling, occurrence data provides evidence of products on the market actually containing the ingredient. Three case studies are presented using this tiered approach to illustrate progressive refinement. The scale of refinements from Tier1 to Tier2+ modelling for the ingredients, propyl paraben, benzoic acid and DMDM hydantoin were: 0.492 to 0.026; 1.93 to 0.042 and 1.61 to 0.027 mg/kg/day exposure dose. For propyl paraben, moving from Tier1 to Tier2+ represents a refinement from 49-fold to 3-fold overestimate of exposure when compared to a maximum estimate of 0.01 mg/kg/day exposure seen in human studies. Such refinements from worst case to realistic levels of exposure estimation can be critical in the demonstration of consumer safety.

Retardation of acquisition after conditioned inhibition and latent inhibition training in human causal learning.

Inhibitory stimuli are slow to acquire excitatory properties when paired with the outcome in a retardation test. However, this pattern is also seen after simple nonreinforced exposure: latent inhibition. It is commonly assumed that retardation would be stronger for a conditioned inhibitor than for a latent inhibitor, but there is surprisingly little empirical evidence comparing the two in either animals or humans. Thus, retardation after inhibitory training could in principle be attributable entirely to latent inhibition. We directly compared the speed of excitatory acquisition after conditioned inhibition and matched latent inhibition training in human causal learning. Conditioned inhibition training produced stronger transfer in a summation test, but the two conditions did not differ substantially in a retardation test. We offer two explanations for this dissociation. One is that learned predictiveness attenuated the latent inhibition that otherwise would have occurred during conditioned inhibition training, so that retardation in that condition was primarily due to inhibition. The second explanation is that inhibitory learning in these experiments was hierarchical in nature, similar to negative occasion-setting. By this account, the conditioned inhibitor was able to negatively modulate the test excitor in a summation test, but was no more retarded than a latent inhibitor in its ability to form a direct association with the outcome. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Environmental exposure assessment of co-formulants in plant protection products under REACH.

It is a regulatory requirement to assess co-formulants in plant protection products (PPP) under the European Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) legislation. The standard environmental exposure assessment framework for chemicals under REACH is a multicompartmental mass-balanced model and, at the local scale, is designed for use with urban (wide dispersive) or industrial (point source) emissions. However, the environmental release of co-formulants used in PPP is to agricultural soil and indirectly to waterbodies adjacent to a field and, for sprayed products, to the air. The Local Environment Tool (LET) has been developed to assess these specific emission pathways for co-formulants in a local-scale REACH exposure assessment, based on standard approaches and models used for PPP. As such, it closes a gap between the standard REACH exposure model's scope and REACH requirements to assess co-formulants in PPP. When combined with the output of the standard REACH exposure model, the LET includes an estimate of the contribution from other nonagricultural background sources of the same substance. The LET is an improvement over the use of higher tier PPP models for screening purposes because it provides a simple standardized exposure scenario. A set of predefined and conservatively selected inputs allows a REACH registrant to conduct an assessment without requiring detailed knowledge of PPP risk assessment methods or typical conditions of use. The benefit to the co-formulant downstream user (formulators) is a standardized and consistent approach to co-formulant assessment, with meaningful and readily interpretable conditions of use. The LET can serve as an example to other sectors of how to address possible gaps in the environmental exposure assessment by combining a customized local-scale exposure model with the standard REACH models. A detailed conceptual explanation of the LET model is provided here together with a discussion on its use in a regulatory context. Integr Environ Assess Manag 2023;19:1544-1554. © 2023 BASF SE, Bayer AG et al. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

Look at me now! Enfacement illusion over computer-generated faces.

According to embodied cognition research, one's bodily self-perception can be illusory and temporarily shifted toward an external body. Similarly, the so-called "enfacement illusion" induced with a synchronous multisensory stimulation over the self-face and an external face can result in implicit and explicit changes in the bodily self. The present study aimed to verify (i) the possibility of eliciting an enfacement illusion over computer-generated faces and (ii) which multisensory stimulation condition was more effective. A total of 23 participants were asked to look at a gender-matched avatar in three synchronous experimental conditions and three asynchronous control conditions (one for each stimulation: visuotactile, visuomotor, and simple exposure). After each condition, participants were asked to complete a questionnaire assessing both the embodiment and the enfacement sensations to address different facets of the illusion. Results suggest a stronger effect of synchronous vs. asynchronous stimulation, and the difference was more pronounced for the embodiment items of the questionnaire. We also found a greater effect of visuotactile and visuomotor stimulations as compared to the simple exposure condition. These findings support the enfacement illusion as a new paradigm to investigate the ownership of different face identities and the specific role of visuotactile and visuomotor stimulations with virtual reality stimuli.