ABOUT two years ago, in a previous communication, attention was directed to the roentgen-ray treatment in true bronchial asthma and various types of chronic bronchitis. Since that time further experience has shown that the method has a real place in therapy. In the treatment of bronchial asthma, the first and most important consideration is the matter of diagnosis. It is extremely important that the treatment be limited to cases of true bronchial asthma; otherwise unnecessary treatment is apt to be applied with no beneficial results. Numerous cases of supposed bronchial asthma have been proved later to be merely cardiac asthma or simple bronchitis without complications. The essential element is the proof that we are dealing with a true protein intoxication. Of course, it will be urged that in these cases the newer and more modern methods of treatment, such as vaccination, etc., should be used. This is quite true, and, in fact, the vast majority of cases that have come to my attention for treatment have been those in which all the modern methods have already been applied but without any real lasting benefit. Many were cases in which numerous operations had been performed, particularly in the upper respiratory tract. In selecting the cases for treatment a careful study of the sputum is often important. Those patients who have the characteristic elements in their sputum, such as pearl bodies, Curschmann's spirals, and eosinophiles, are apt to be most responsive to roentgen-ray therapy. Cases which already have marked emphysema, and particularly hypertonia, are least benefited. However, treatment should not be withheld from even these terminal types, as there is no danger of making the condition worse if the treatment is applied cautiously. No estimate as to prognosis can be based upon the blood examination alone. Some of the observers have felt that individuals with high eosinophile counts in the blood would respond better to X-ray treatment than those without. The careful work of Schilling shows that this idea has no real foundation. The matter of duration of the disease also is of little help in prognosis. Many cases of years' duration have reacted as well or better than others of short duration. This does not of course apply to old cases with emphysema. When the latter is present as a complication the condition is usually refractory. I have previously described the two methods of treatment with X-rays, the direct and the indirect. In the first, the rays are applied directly to the chest. In the indirect method, the rays are applied to distant regions, such as the spleen, the pituitary, adrenals, etc. There is no unanimity of opinion in the current literature as to the best method of treatment. Klewitz in his most recent contribution has reported 121 cases, all of them treated by the direct method alone.
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