Health communication is used as an effort to prevent transmission of COVID-19. The problem is that until now the community does not know how to prevent the spread and break the chain of transmission of COVID-19. Researchers chose the practice of implementing health communication held in the work area of UPT Puskesmas Simpang Empat 1, Banjar Regency, South Kalimantan Province for prevention and transmission through the COVID-19 health protocol. The research method used is a descriptive case study method. The object of his research is the practice of implementing health communication to prevent the transmission of COVID-19 by implementing the Adaptation of New Habits (IMR). The research results show that the implementation of health communication is influenced by three aspects, namely input, process and output. The risk-based health communication that has been carried out has proven to bring changes to the knowledge, attitudes and behavior of the community in dealing with the COVID-19 pandemic.