Similar Events Research Articles

Transfer Learning for Transportation Demand Resilience Pattern Prediction Using Floating Car Data

Understanding the response of a transportation system to disruptive events is significant for evaluating the resilience of the system. However, data collection during such events is always challenging, and the data volume is insufficient for building a robust model. Transfer learning provides an effective solution to this problem. In this study, we propose a floating car data (FCD) driven transfer learning framework for predicting the resilience of target transportation systems to similar disruptive events to those that have ever occurred in the source systems. The core of the framework is an unsupervised pattern extractor that combines the k-Shape clustering and Bayes inference methods for extracting resilience patterns from the FCD collected in the source systems during the disruption period. The extracted patterns can then be used to assist in the prediction of the resilience of the target systems. We examine the effectiveness of the proposed framework by conducting a case study under the context of the COVID-19 pandemic, in which the source domain cities include Antwerp and Bangkok, and the target domain city is Barcelona. Results show that the extracted resilience patterns can improve the prediction performance of transfer learning neural networks with less pre-event information and limited data volume.

Establishment of acquired tracheoesophageal fistula using a modified magnetic compression technique in rabbits and its postmodeling evaluation.

Previous studies have validated the efficacy of both magnetic compression and surgical techniques in creating rabbit tracheoesophageal fistula (TEF) models. Magnetic compression achieves a 100% success rate but requires more time, while surgery, though less frequently successful, offers rapid model establishment and technical maturity in larger animal models. To determine the optimal approach for rabbit disease modeling and refine the process. TEF models were created in 12 rabbits using both the modified magnetic compression technique and surgery. Comparisons of the time to model establishment, success rate, food and water intake, weight changes, activity levels, bronchoscopy findings, white blood cell counts, and biopsies were performed. In response to the failures encountered during modified magnetic compression modeling, we increased the sample size to 15 rabbit models and assessed the repeatability and stability of the models, comparing them with the original magnetic compression technique. The modified magnetic compression technique achieved a 66.7% success rate, whereas the success rate of the surgery technique was 33.3%. Surviving surgical rabbits might not meet subsequent experimental requirements due to TEF-related inflammation. In the modified magnetic compression group, one rabbit died, possibly due to magnet corrosion, and another died from tracheal magnet obstruction. Similar events occurred during the second round of modified magnetic compression modeling, with one rabbit possibly succumbing to aggravated lung infection. The operation time of the first round of modified magnetic compression was 3.2 ± 0.6 min, which was significantly reduced to 2.1 ± 0.4 min in the second round, compared to both the first round and that of the original technique. The modified magnetic compression technique exhibits lower stress responses, a simple procedure, a high success rate, and lower modeling costs, making it a more appropriate choice for constructing TEF models in rabbits.

Geological study of an outburst flood event in the upper Yangtze River and risk of similar extreme events

Outburst flood sediments are studied on the upper course of the Yangtze River (known as the Jinsha River) where is a key region for the development of hydroelectric power. As the history and magnitude of outburst flooding in this stretch of the Jinsha River during historic times has remained largely undocumented, we have endeavored as part of this study to conduct field investigations into, and provide numerical dating (using OSL and 14C dating techniques) of outburst flood evidence found in the First Bend area of the Yangtze River. Carbonized nutshells and charcoal from the ancient settlement yielded 14C ages that precisely pinpointed an outburst flood event ∼1200–1300 cal yr BP, during China's Tang Dynasty (618–907 CE). However, OSL ages using the minimum age model for all outburst flood samples ranged from 9.1 to 1.8 ka, which was ∼0.5–7.8 ka older than the 14C-dated outburst flood. This discrepancy suggests a potential overestimation of quartz age when dating outburst flood sediments from the Holocene period. Furthermore, using 2D hydraulic modeling, we estimated the magnitude of the aforementioned outburst flood, revealing a reconstructed peak flow discharge of 51,000–55,300 m3/s. This discharge was three times greater than the 10,000-year flood for the hydroelectric power station nearest to the study area. Our study underscores the significant role of combining archaeological and geological evidence in enhancing paleoflood hydrology research. Through a multidisciplinary approach, our findings emphasize the importance of paleoflood hydrology studies in comprehending both the latent and catastrophic flood risks in alpine mountain areas amid the context of global warming. Key points•A series of outburst flood sediments was identified in the First Bend area of the Yangtze River, with a maximum flood water surface ∼86 m high above modern river level.•The obtained 14C ages would suggest that the outburst flood occurred at ∼1200–1300 cal yr BP in the Tang Dynasty (618–907 CE) of China.•The reconstructed peak flow discharge (51,000–55,300 m3/s) is larger than the three times of the 10,000-yr flood for the nearest hydropower station to the study site.

Web-based telemonitoring of visual function and self-reported postoperative outcomes in cataract care: international multicenter randomized controlled trial.

To compare web-based, self-administered follow-up after cataract surgery to conventional face-to-face follow-up. Eye clinics in the Netherlands, Austria, and Germany. Randomized controlled trial with an embedded method comparison study (ClinicalTrials.gov: NCT04809402). Routine patients with cataract were randomized into 2 groups: The telemonitoring group undertook web-based vision self-assessments and questionnaires from home, while the usual care group received conventional care. All participants had a 4- to 6-week postoperative clinic visit for safety and validation purposes. Outcomes included, the web test's accuracy for assessing postoperative visual acuity (VA) and refractive error, adverse event rates, and patient-reported outcome measurements (PROMs). 94 participants (188 eyes) were enrolled. Web-based uncorrected distance VA testing demonstrated a negligible mean difference (-0.03 ± 0.14 logMAR) when compared with conventional Early Treatment Diabetic Retinopathy Study chart testing, with 95% limits of agreement ranging from -0.30 to 0.24 logMAR. The web-based refraction assessment overestimated the postoperative refractive error (mean difference in spherical equivalent 0.15 ± 0.67 diopters), resulting in a poorer corrected distance VA compared with subjective refraction (mean 0.1 vs -0.1 logMAR). Rates of adverse events and unscheduled consultations were minimal across both groups. Preoperative and postoperative PROM questionnaires had a 100% response rate. Visual functioning (Catquest-9SF and National Eye Institute Visual Function Questionnaire-25) improved postoperatively (mean improvement -0.80 and 16.70, respectively) and did not significantly differ between the 2 groups. The patients with cataract in this study effectively provided postoperative outcome data using a web interface. Both conventional and web-based follow-ups yielded similar PROMs and adverse event rates. Future developments should reduce the variability in the web-based VA test and yield representative refraction outcomes.

Extreme iron cycling in a coastal lake-lagoon system driven by interactions between climate and entrance management

Intermittently closed and open coastal lakes and lagoons (ICOLLs) are ecologically important and hydrologically sensitive estuarine systems. We explore how extreme drought and ICOLL entrance management intersect to influence the geochemical cycling of iron. Opening the ICOLL entrance just prior to an extreme drought in 2019 led to prolonged extremely low water levels, thereby exposing intertidal/subtidal sulfidic sediments and causing oxidation of sedimentary pyrite. Subsequent reflooding of exposed sediments for ∼4 months led to extremely elevated Fe2+(aq) (>10 mM) in intertidal hyporheic porewaters, consistent with Fe2+(aq) release via pyrite oxidation and via reductive dissolution of newly-formed Fe(III) phases. Re-opening the ICOLL entrance caused a rapid fall in water levels (∼1.5 m over 7 d), driving the development of effluent groundwater gradients in the intertidal zone, thereby transporting Fe2+-rich porewater into surface sediments and surface waters. This was accompanied by co-mobilisation of some trace metals and nutrients. On contact with oxic, circumneutral-pH estuarine water, the abundant Fe2+(aq) oxidised, forming a spatially extensive accumulation of poorly crystalline Fe(III) oxyhydroxide floc (up to 25 % Fe dry weight) in shallow intertidal zone benthic sediments throughout the ICOLL. Modelling estimates ∼4050 × 103 kg of poorly-crystalline Fe was translocated into surficial sediments. The newly formed Fe(III)-oxyhydroxides serve as a metastable sink encouraging enrichment of both phosphate and various trace metal(loid)s in near-surface sediments, which may have consequences for future cycling of nutrients, metals and ICOLL ecological function. The additional Fe also may enhance ICOLL sensitivity to similar future drought events by encouraging pyrite formation in shallow (<5 cm) benthic sediments. This system-wide translocation of Fe from deeper sediments into surficial benthic sediments represents a form of geochemical hysteresis with an uncertain recovery trajectory. This study demonstrates how climate extremes can interact with anthropogenic management to amplify ICOLL hydrological oscillations and influence biogeochemistry in complex ways.

Leveraging Generative Artificial Intelligence to Broaden Participation in Computer Science

Generative Artificial Intelligence (AI) was incorporated into a competitive programming event that targeted undergraduate students, including those with little programming experience. The competition incorporated a range of challenge design approaches that promoted meaningful interaction with generative AI system, even while keeping the challenge difficulty level to an appropriate level. An analysis of survey responses and competition data showed that this format lowered barriers to participation, successfully engaged students throughout the competition, and increased the likelihood that they would participate in a similar event. In an extension of this work, a professional development workshop for high school teachers is being developed, along with a contest for high school students. Participant surveys and logs of interaction with the contest and generative AI systems will be analyzed to measure the effect of generative AI on student self-efficacy and suggest ways to integrate generative AI instruction into computer science curriculum.

The Spatial Scale and Spread of Child Victimization.

Previous research shows that large, densely populated urban areas have higher rates of child victimization that have persisted over time. However, few investigations have inquired about the processes that produce and sustain hot and cold spots of child victimization. As a result, the mechanisms that produce the observed spatial clustering of child victimization, and hence "why" harms against children tend to cluster in space, remains unknown. Does the likelihood of being a victim of violence in one location depend on a similar event happening in a nearby location within a specified timeframe? Rather, are child victims of violence more likely to reside in suboptimal neighborhood conditions? This paper aims to present an analytical and theoretical framework for distinguishing between these locational (point) processes to determine whether the empirical spatial patterns undergirding child victimization are more reflective of the "spread" via contagion (i.e., dependency) or whether they are produced by neighborhood structural inequality resulting from spatial heterogeneity. To detect spatial dependence, we applied the inhomogeneous K-function to Los Angeles Medical Examiner data on child homicide victim locations while controlling for regional differences in victimization events (i.e., heterogeneity). Our analysis found strong evidence of spatial clustering in child victimization at small spatial scales but inhibition at larger scales. We further found limited support for the spatiotemporal clustering of child victimization indicative of a contagion effect. Overall, our results support the role of neighborhood structural vulnerability in the underlying mechanisms producing patterns of child victimization across Los Angeles County. We conclude by discussing the policy implications for understanding this spatial patterning in geographical context and for developing effective and targeted preventive interventions.

WAITING FOR A CONCERT IN SUMMER HEAT: A TRANSIENT ST ELEVATION IN A YOUNG MAN

Abstract A 22–year–old man, without prior cardiological history, was waiting for a concert to start many hours in summer heat. Suddenly he started to feel chest pain, dyspnea, and palpitations. Electrocardiogram (EKG), registered from first aid responders, showed a ST elevation in V1–V3 leads and ventricular repolarization alterations in inferior leads. The patient was brought to Emergency department (ED) where a new EKG resulted normalized, blood test samples showed High Sensitive Troponin T (HsTn) 35 ng/L (at plateau in three seriate measures), serum creatinine 2.0 mg/dL, total Creatine Kinase 646U/L, Ck–MB 10.6 ng/mL, Reactive C Protein (RCP) 1.2 mg/dl. The toxicological evaluation was negative. Transthoracic Echocardiography (TTE) did not show any regional ventricular kinesis alterations nor valvular defects, global systolic function was preserved. A Coronary Computed Tomography (CT) scan showed an intramyocardial bridge on Anterior Descending (DA) Coronary Artery associated to 7 mm pericardial effusion without coronary stenosis. A Cardiac Magnetic Resonance (CMR) with gadolinium was performed, which did not show (in T2 mapping sequences) oedema nor Late Gadolinium Enhancement (LGE). Considering a coexistence of Brugada syndrome pattern at EKG, an Ajmaline testing was performed, which resulted negative. Discussion: Dehydration due to any intake of water after standing many hours in summer heat could have been the trigger for a vasospasm of DA that in this patient has a partially intramyocardial course. This anatomical finding was not known until CT scan was performed. Our diagnostic hypothesis of a vasospasm on DA is supported by EKG alterations and elevation enzymes of myocardionecrosis, in absence of any coronary stenosis. Elevated creatinine values in the absence of other renal concomitant comorbidities were suggestive for acute dehydration too. Differential diagnosis took also into consideration myo–pericarditis, especially for the pericardial effusion finding revealed by CT scan: this diagnosis was not confirmed through CMR but also by the evolution of clinical conditions of our patient. We discharged the patient, asymptomatic with normalized renal function after some intravenous hydration and we prescribed a calcium channel blocker. At a follow up visit, three months after the acute event, our patient was in good clinical condition and denied occurrence of any other similar events.

Simulation and Management Impact Evaluation of Debris Flow in Dashiling Gully Based on FLO-2D Modeling

Dashiling Gully, located in Miyun District, Beijing, exhibits a high susceptibility to debris flow due to its unique geological and topographical characteristics. The area is characterized by well-developed rock joints and fissures, intense weathering, a steep gradient, and a constricted gully morphology. These factors contribute to the accumulation of surface water and loose sediment, significantly increasing the risk of debris flow events. Following a comprehensive field geological investigation of Dashiling Gully, key parameters for simulation were obtained, including fluid weight, volume concentration, and rainfall. The formation and development conditions of potential mudslides were analyzed, and numerical simulations were conducted using FLO-2D software (version 2009) to assess scenarios with rainfall probabilities of 1 in 30, 50, and 100 years. The simulations accurately reconstructed the movement velocity, deposition depth, and other critical movement characteristics of mudslides under each rainfall scenario. Using ArcGIS, pre- and post-treatment hazard zoning maps were generated for Dashiling Gully. Furthermore, the efficacy of implementing a retaining wall as a mitigation measure was evaluated through additional numerical simulations. The results indicated that mudslide velocities ranged from 0 to 3 m/s, with deposition depths primarily between 0 and 3 m. The maximum recorded velocity reached 3.5 m/s, corresponding to a peak deposition depth of 4.31 m. Following the implementation of the retaining wall, the maximum deposition depth significantly decreased to 1.9 m, and high-risk zones were eliminated, demonstrating the intervention’s effectiveness. This study provides a rigorous evaluation of mudslide movement characteristics and the impact of mitigation measures within Dashiling Gully. The findings offer valuable insights and serve as a reference for forecasting and mitigating similar mudslide events triggered by heavy rainfall in gully mudslides.

On-Farm Hog Processing Demonstration for Teenage Exhibitors: Blending Academic, Laboratory, and Farm-Based Learning

COVID-19 challenges induced a U.S. meatpacking industry bottleneck. [University] Extension identified the need and responded by creating a three-step hands-on training for teenage junior fair exhibitors. [University] Extension Meat Scientist and graduate students assisted in demonstrating an on-farm hog harvest and processing event in collaboration with a local Extension office for 4-H and FFA teenagers. To add a practical perspective, a local hog-producing and harvesting family was asked to assist with the event. An online post-survey reflected 90-100% gains in five educational areas and 100% said they would a similar event in the future and recommend it to a friend.

Paleoarchean sedimentation and Mesoarchean high-temperature metamorphism in northeastern Brazil: Tracing sources and depositional ages in polymetamorphic rocks

Supracrustal rocks offer a window into tectonic processes of the early Earth, since they are common in the Archean lithosphere. However, these rocks are usually affected by several episodes of metamorphism that can compromise their UPb systematics, leading to equivocal interpretations of depositional ages and sources. In northeast Brazil, supracrustal rocks are frequent within the Archean basement of the São José do Campestre Massif. These metapelitic migmatites show a high-temperature mineral assemblage, with garnet + sillimanite ± spinel and retrograde cordierite, with abundant anatectic melt migration at conditions of upper amphibolite to granulite facies. Zircon UPb dating coupled to trace elements analysis through LA-ICP-MS, as well as zircon internal zoning patterns suggest a maximum depositional age of 3305 ± 16 Ma followed by high-temperature metamorphism in the Mesoarchean, Paleoproterozoic and Neoproterozoic. Mesoarchean high temperature metamorphism occurred between 3084 ± 4 and 3006 ± 6 Ma and generated a wide range of textures that could be grouped in, at least, three stages of zircon growth. The first, during prograde heating, led to dissolution of detrital cores through the process of Ostwald Ripening and reprecipitation in oscillatory zoned rims. The second, probably at peak conditions, occurred above the stability of monazite, as evidenced by high Th/U ratios within zircon grains, rounded shape and sector-zoned cores. The third, during retrograde cooling, is mostly driven by garnet breakdown, and resulted in the crystallization of convoluted rims. Ti-in-zircon temperatures indicate minimum temperatures of 712 ± 21 °C for prograde/retrograde stages and 881 ± 50 °C for peak conditions. The Paleoarchean sedimentation and Mesoarchean metamorphism are coeval with similar events in Kaapvaal and Dharwar Cratons (South Africa and South India, respectively), but show no correlation to any Archean domains in South America to date. Solid-state recrystallization during the Paleoproterozoic (ca. 2.0 Ga) and the Neoproterozoic (ca. 0.6 Ga) correlates with orogenic events in both the Borborema Province and São Francisco Craton, suggesting a common evolution since the Rhyacian.

International Bibliographic Congresses: Through the Prism of History to the Future

The article presents the International Bibliographic Congress, scheduled for September 2025 in Yakutsk, which will continue the tradition of similar events in recent decades. The first International Bibliographic Congress was held in 2010 in St. Petersburg, the second — in 2015 in Moscow, the third — in 2021 in Novosibirsk. Each time they were cities, and respectively libraries (Russian National Library, Russian State Library, State Public Scientific and Technical Library of the Siberian Branch of the Russian Academy of Sciences), preserving and developing rich bibliographic traditions. It is shown that by holding international bibliographic congresses, the bibliographic community of Russia aims to achieve several goals: 1) to identify the current (at the time of the next congress) state of bibliographic science and practice not only in Russia, but also in other countries of the world; 2) to discuss the most pressing problems facing bibliographers; 3) to outline ways of further development of bibliographic activity in the near future and in the distant future.

Enterprise violation risk deduction combining generative AI and event evolution graph

AbstractIn the current realms of scientific research and commercial applications, the risk inference of regulatory violations by publicly listed enterprises has attracted considerable attention. However, there are some problems in the existing research on the deduction and prediction of violation risk of listed enterprises, such as the lack of analysis of the causal logic association between violation events, the low interpretability and effectiveness of the deduction and the lack of training data. To solve these problems, we propose a framework for enterprise violation risk deduction based on generative AI and event evolution graphs. First, the generative AI technology was used to generate a new text summary of the lengthy and complex enterprise violation announcement to realize a concise overview of the violation matters. Second, by fine‐tuning the generative AI model, an event entity and causality extraction framework based on automated data augmentation are proposed, and the UIE (Unified Structure Generation for Universal Information Extraction) event entity extraction model is used to create the event entity extraction for listed enterprises ‘violations. Then, a causality extraction model CDDP‐GAT (Event Causality Extraction Based on Chinese Dictionary and Dependency Parsing of GAT) is proposed. This model aims to identify and analyse the causal links between corporate breaches, thereby deepening the understanding of the event logic. Then, the merger of similar events was realized, and the causal correlation weights between enterprise violation‐related events were evaluated. Finally, the listed enterprise's violation risk event evolution graph was constructed, and the enterprise violation risk deduction was carried out to form an expert system of financial violations. The deduction results show that the method can effectively reveal signs of enterprise violations and adverse consequences.

Earthquake “doublets” – case studies for Kresna-Kroupnik (Bulgaria-M7.8) and Gaziantep–Kahramanmaraş (Turkey-M7.8)

The devastating earthquakes (M7.8 and M7.5) on 6th February 2023 demonstrate the power of the nature and weakness and fragility of the human society. Affecting more than 20 million people in Turkey, the death poll reaches about 60 000 deaths and about three times more injured, 120 000 buildings destroyed and more than 60 billion economical losses in Turkey and Syria. This tremendous seismic event at the same time gave the possibility to study and extract the lessons learned and to prevent heavy consequences when next similar event occurred. Following the context of the specific behavior of the seismic process this event can be attributed to the terminology using the word “doubles” of such a combination of two very strong earthquakes occurred in close space and time window – near Gaziantep and Kahramanmaraş. The two strong earthquakes of 6th February demonstrated all peculiarities of the seismic process and its geophysical, seismological and social consequences. The similar effects have been observed also in 1904 in Bulgaria. On 4th of April, 1904 two very strong earthquakes (M7.2 and M7.8) occurred in a very close time and space domain. These seismic events can also be classified as a “doublet”. So the comparative analysis of such strong earthquakes can help to understand better the seismic process and the following risks for the population, infrastructure and the affected countries as a whole. This paper is targeted to the comparison of the case studies to the seismic doublets in Bulgaria and Turkey and their peculiarities with a focus on the seismic process, destructions, negative social consequences and the specifics if they exist and to extract knowledge which can be useful for the prevention of all possible negatives. The results obtained suggest that similar seismic events might have very different geophysical, seismological and social consequences due to the resilience and environmental peculiarities of the specifically affected sites.

Mitigating against relative age effects in youth Track & Field: Validating corrective adjustment procedures across multiple events

ObjectivesWith the aim to better identify talented Track & Field performance development, this study estimated the relationships between chronological (decimal) age with 60-m sprint, high jump, triple jump, and pole vault performance. Then, to mitigate against expected Relative Age Effects (RAEs), Corrective Adjustment Procedures (CAPs) were applied to an independent sample. DesignMixed-longitudinal design examining public data between 2005 and 2019. MethodsThe performances of 5339 Italian sprinters and jumpers (53.1 %) spanning 11.01–17.99 years of age were examined, with trendlines between chronological age and performance established. Related to an independent sample (N = 40,306; female 45.5 %), trendlines were then utilised to apply CAPs and adjust individual performance. Considering raw and adjusted performance data, RAE distributions were examined for the top 25 % and 10 % performers. ResultsFor all male and female events, quadratic models best summarised the relationships between chronological age and performance (R2 = 0.74–0.89). When examining independent athletes in similar event, RAEs were more pronounced in males (Cramer's V = 0.35–0.14) than females (Cramer's V = 0.29–0.07). For both sexes, RAE magnitude decreased with age and increased according to performance level (i.e., Top25%–Top10%). However, following CAP applications, RAEs were reduced or removed within annual age groups and performance levels. ConclusionsWith RAEs prevalent across Italian youth Track & Field events, findings validate CAPs as a strategy to account for the influence of relative age differences on athletic performance. CAPs help establish a more equitable strategy for performance evaluation and could help improve the efficacy of long-term athlete development programming.

PROMOTING PARTICIPATION IN COMMUNITY RUNNING FESTIVALS FOR INDIVIDUALS WITH PARKINSON’S DISEASE - A MODEL FOR MEANINGFUL PARTICIPATION

INTRODUCTION AND AIMS Community-based walking and running groups have become popular social phenomena in recent years. Integrating individuals with Parkinson’s disease into community-based walking and running events confers multiple socio-biological benefits, but may be problematic for individuals with Parkinson’s disease in the later stages of the disease progression. METHODS This research evaluates the participation of a group of individuals with Parkinson’s disease in a long-standing community running festival, the Gold Coast Marathon Festival. Evaluation of participation comprised: 1) description of the activities undertaken by the Exercise Physiologists to ensure the safe and effective participation of the interested parties; and 2) a qualitative evaluation of the participant’s experiences with the event. RESULTS Ten adults with Parkinson’s disease (70% male), mean age 69.6 ± 7.8 years (range = 57-79) participated. Time post-diagnosis ranged 1 to 15 years (mean = 6.7 ± 4.4 years). Participants registered to complete one of two distances: 5.7 km (n = 9) or 700 m (n = 1). Activities undertaken by the Exercise Physiologist prior to participating were divided into three themes: participation, safety, and administrative requirements. Participant experiential data was divided into six themes: preparation prior to participating; pre participation planning and organisation; reasons/meaning for choosing to participate; barriers for participating; event recovery; and event suitability. The data collated was triangulated to provide recommendations to facilitate participation in similar events. CONCLUSION The results of this study demonstrate that with effective planning and coordination, participation in community-based walking and running events confer physical and mental health benefits for individuals with Parkinson’s disease. However, significant barriers need to be addressed prior to participation to ensure meaningful participation. This paper provides recommendations for practicing Exercise Physiologists who wish to promote participation of their own clients with Parkinson’s disease in similar initiatives.

Towards the systematic reconnaissance of seismic signals from glaciers and ice sheets – Part 2: Unsupervised learning for source process characterization

Abstract. Given the high number and diversity of events in a typical cryoseismic dataset, in particular those recorded on ice sheet margins, it is desirable to use a semi-automated method of grouping similar events for reconnaissance and ongoing analysis. We present a workflow for employing semi-unsupervised cluster analysis to inform investigations of the processes occurring in glaciers and ice sheets. In this demonstration study, we make use of a seismic event catalogue previously compiled for the Whillans Ice Stream, for the 2010–2011 austral summer (outlined in Part 1, Latto et al., 2024). We address the challenges of seismic event analysis for a complex wave field by clustering similar seismic events into groups using characteristic temporal, spectral, and polarization attributes of seismic time series with the k-means++ algorithm. This provides the basis for a reconnaissance analysis of a seismic wave field that contains local events (from the ice stream) set in an ambient wave field that itself contains a diversity of signals (mostly from the Ross Ice Shelf). As one result, we find that two clusters include stick-slip events that diverge in terms of length and initiation locality (i.e., central sticky spot and/or the grounding line). We also identify a swarm of high-frequency signals on 16–17 January 2011 that are potentially associated with a surface melt event from the Ross Ice Shelf. Used together with the event detection presented in Part 1, the semi-automated workflow could readily be generalized to other locations and, as a possible benchmark procedure, could enable the monitoring of remote glaciers over time and comparisons between locations.

MELTEMI and COLUMBA: 5-Year Comparative Safety Analysis of Benralizumab and Mepolizumab

Benralizumab and mepolizumab are interleukin (IL)-5Rα/interleukin-5-targeted monoclonal antibodies indicated as add-on treatments for patients with uncontrolled severe eosinophilic asthma (SEA). To evaluate and compare the safety of benralizumab and mepolizumab among patients with SEA treated in MELTEMI and COLUMBA open-label, long-term extension studies, respectively. MELTEMI was an extension study of benralizumab every 4 weeks (q4w) or every 8 weeks (q8w) for adults (aged 18-75 y) with SEA. MELTEMI participants transitioned from the BORA extension, preceded by participation in 1 of 3 placebo-controlled studies (SIROCCO, CALIMA, or ZONDA). COLUMBA was an extension study of mepolizumab for patients (aged ≥ 12 y) with SEA who transitioned from the dose-ranging DREAM study. Safety endpoints were presented as drug exposure patient-years (MELTEMI, q4w 784.28, q8w 797.03; COLUMBA 1,201) for nonserious adverse events, serious adverse events, and infections; malignancies were counted numerically. This analysis included 446 MELTEMI patients (benralizumab q4w 220; benralizumab q8w 226) and 347 COLUMBA patients (mepolizumab q4w). Viral upper respiratory tract infection was the most common nonserious adverse event in both studies (MELTEMI q8w 46.5%; q4w 47.3%; COLUMBA, 48.7%). Asthma-related events were the most common serious adverse events in both studies: MELTEMI 8.0% (q8w) and 8.6% (q4w) and COLUMBA 9.5%. Serious infections included pneumonia (MELTEMI q8w, 2 [0.9%]; COLUMBA, 6 [1.7%]); cellulitis (MELTEMI q8w, 1 [0.4%]; COLUMBA, 2 [0.6%]); and respiratory tract infections (COLUMBA, 2 [0.6%]). COLUMBA reported 6 malignancies and MELTEMI reported 4 malignancies in each group. This analysis demonstrated generally similar safety events between mepolizumab and benralizumab in patients with SEA.

Dynamic pathway linking Pakistan flooding to East Asian heatwaves.

In July to August 2022, Pakistan suffered historic flooding while record-breaking heatwaves swept southern China, causing severe socioeconomic impacts. Similar extreme events have frequently coincided between two regions during the past 44 years, but the underlying mechanisms remain unclear. Using observations and a suite of model experiments, here, we show that the upper-tropospheric divergent wind induced by convective heating over Pakistan excites a barotropic anomalous anticyclone over eastern China, which further leads to persistent heatwaves. Atmospheric model ensemble simulation indicates that this dynamic pathway linking Pakistan flooding and East Asian heatwaves is intrinsic to the climate system, largely independent of global sea surface temperature forcing. This dynamic connection is most active during July to August when convective variability is large over Pakistan and the associated divergent flow excites barotropic Rossby waves that propagate eastward along the upper troposphere westerly waveguide. This robust waveguide and the time delay offer hopes for improved subseasonal prediction of extreme events in East Asia.

Theoretical foundations of development and implementation of event projects for trade enterprises

The article is devoted to analyzing the essence of the concept of «event» and improving its classification and substantiation of the principles of its implementation through the stages of development of an event for trade enterprises. A morphological analysis of the concept of «event» is carried out by allocating the optimal definition. A primary classification of the concept of «event» (by planning) is proposed, where the planned event is defined, which is the subject of the study of event management. They require setup, guidance, managers, and a specific time. An unplanned event is an accident, natural disaster, and other similar events. The classification of events by size and scale has been improved, dividing them into mega, business cards, central, and local events. The main mistakes that are made when organizing an event are identified, which include the fact that the event is created only in order to hold it and then be proud, but at the same time, the event does not cover the target audience at all, or is devoid of meaningful meaning for it; And also when creating an event, the company is so fixated on its importance that it forgets about the interests of consumers. It is determined that the development of the event includes the definition of its structure, which includes planning meetings, the work of sections, the cultural program, and the duration of each stage. The second step is to choose the time and place of the event, which should consider the target audience, season, weather conditions, and parallel events because the wrong choice can affect attendance. As the final document, the event scenario should detail all aspects of the organization. The third stage involves the development of content and script, where all elements should be harmoniously combined. The role of information support in the event management of projects is outlined, outlining the need to inform the audience in advance about the event through various channels, depending on its format and scale. Keywords: event, events, technologies, event management, event project.