Signs Of Urethritis Research Articles

Incidence and treatment of chlamydia trachomatis genital infection in Belfast.

Chlamydia trachomatis was isolated from 35% of urethral swabs taken from 100 men with non-gonococcal urethritis (NGU). Eleven out of 53 female contacts of NGU (20.7%) were alsoC. trachomatis positive. In 21 female contacts ofC. trachomatis positive men, 9 (42.9%) wereC. trachomatis positive. All patients becameC. trachomatis negative folowing oxytetracycline therapy but 50% ofC. trachomatis positive and 47.6% ofC. trachomatis negative men required further treatment for symptoms and signs of urethritis.

Activity of erythromycin against chlamydiaein vitroandin vivo, and its use in genital Chlamydia infections

SummaryIn addition to mycoplasmas, chlamydiae appear to play a significant role as pathogenic agents in abacterial urethritis and in the post-gonorrhoeal syndrome. Forty patients with genital Chlamydia infections associated with subjective and objective signs of urethritis and/or adnexitis were treated for 14 days with 1 g erythromycin stearate twice daily. In 11 patients, the erythromycin sensitivity of the Chlamydia strains was tested, and the MIC values were determined. Two groups with different erythromycin sensitivities were found (0.3 μg/ml, and > 5.0 μg/ml). Therapeutically, no in vivo differences between the two Chlamydia groups were found. In 37 patients, the urethritis/adnexitis was controlled; 2 patients failed to respond and 1 admitted not taking the prescribed erythromycin.