The relation of parents personality predisposition to guilt, shame, and fear of death with symptoms ofposttraumatic stress, anxiety, and depression was examined in 67 couples who were the parents of sicknewborn infants previously hospitalized in a Neonatal Intensive Care Unit. The Actor-Partner Interde-pendence Model method of dyadic analysis was used to determine the relation of parents predispositionto guilt, shame, and fear of death to their own posttraumatic stress, anxiety, and depression (actor effect),and to the posttraumatic stress, anxiety, and depression of their partners (partner effect). The couplemembers were not statistically distinguishable by gender. Guilt had a significant actor effect withposttraumatic stress, anxiety, and depression, and a significant partner effect with anxiety and depression.Guilt explained 1518% of the variance in these measures of psychological distress. Fear of death hada significant actor effect with all measures of psychological distress, but none of the partner effects wasstatistically significant. Shame did not predict posttraumatic stress or anxiety, but there was a significantactor effect with depression. Fear of death and shame explained only small proportions (36%) of thevariance in the psychological distress variables with which they had statistically significant relationships.The guilt effects with psychological distress were intrapersonal (actor) and interpersonal (partner),whereas the fear of death and shame effects were intrapersonal. These emotions, particularly fear of deathand shame, tend to be elusive as well as aversive, but they are important forerunners of psychopathologyand deserve specific attention in psychological counseling.Keywords: parents, neonatal intensive care, posttraumatic stress, anxiety, depression