Significant Increase In Magnesium Research Articles

Food to food fortification of whole wheat flour biscuit using moringa leaves powder

The purpose of the research was to use food to food fortification of staples, as a tool to deliver micronutrients especially minerals to the population. In this research moringa leaves powder (MLP), a local nutrient dense source, was utilized for increasing the micronutrients in whole wheat flour biscuit. Microstructural and mineral analysis of whole wheat flour (WWF) and MLP was carried out. WWF biscuit were prepared by incorporating MLP in different percentages (0, 2, 4, 6, 8 and 10%). Mineral profile, phytic acid content and microstructure of the biscuit were analyzed. The microstructural analysis showed that the gluten network was infered by inculsion of MLP, creating some cavities, but the entire protein matrix was not disrupted. The results of the mineral analysis indicated a significant increase in magnesium (42.34%), calcium(84.91%), potassium(49.82%), phosphorus (32.32%) and iron content(50.92%) of the cookies fortified with MLP. Phytic acid of the biscuit decreased from 0.66 to 0.39%. It can be concluded that MLP can be a tool to alleviate malnutrition and solve food insecurity especially in the developing counteries.

Effect of Piper cubeba L. fruit on ethylene glycol and ammonium chloride induced urolithiasis in male Sprague Dawley rats

BackgroundTo investigate the antilithiatic effect of hydroalcoholic extract of Kabab Chini (Piper cubeba L.) fruit in male Sprague Dawley rats. MethodsRats were divided into six groups of six each. Group I received regular rat food and drinking water ad libitum. Groups II to VI were administered with ethylene glycol (EG) 0.75% (V/V) and ammonium chloride (AC) 1% (W/V) in drinking water for 7 days to induce urolithiasis. From 8th day Group I received 1 mL of 5% gum acacia. Group IV was treated with Cystone; V and VI groups with the hydro-alcoholic extract of Piper cubeba L. Treatment was continued for further 14 days, thereafter animals sacrificed. While Group II animals were sacrificed just after 7 days treatment with EG and AC. Group III was left untreated until 14 days and sacrificed on 22nd day. Crystalluria was analyzed on 8th and 22nd day while, urinary calcium, phosphorus, creatinine, sodium and magnesium on 22nd day. Biochemistry and histopathological studies of kidney were also carried out. ResultsTest groups showed significant reduction (p < 0.001) of crystals in urine. Serum creatinine and urea (p < 0.01) were also decreased significantly. Urine analysis showed significant increase in magnesium while calcium, sodium, chloride and phosphorus significantly decreased along with histopathological improvement in kidney tissue in treated groups. ConclusionFrom the above results it can be concluded that hydroalcoholic extract of P. cubeba L. fruit has significant inhibitory effect in calcium oxalate urolithiasis.

Evaluation of cashew nut flour in the production of biscuit

Purpose – The aim of this paper is to promote the utilization and diversification of cashew nuts through its use as a substitute for wheat flour in biscuit production. Design/methodology/approach – Wheat flour was substituted with cashew nut flour (CNF) at levels of 0, 20, 30 and 40 percent in the production of biscuit. The products obtained were subjected to proximate, mineral and sensory analysis. Findings – There was a significant increase in protein and fat contents from 7.75 and 22.11 percent to 12.89 and 32.11 percent, respectively, when CNF increased, whiles carbohydrate decreased from 66.67 to 48.04 percent. A significant increase in magnesium (27.93-97.03 mg/100 g), sodium (198.11-228.02 mg/100 g), phosphorus (55.90-149.00 mg/100 g), potassium (290.40-990.00 mg/100 g), zinc (0.72-2.00 mg/100 g) and iron (0.28-1.00 mg/100 g) was also observed as CNF increased. Sensory analysis revealed that there was no significant difference (p&gt;0.05) between the 20 and 30 percent substituted samples, in terms of overall acceptability. Therefore, wheat flour could be substituted with CNF up to 30 percent in the production of biscuit. Originality/value – This study was done to ascertain the potential use of CNF as a substitute for wheat flour and a nutrient enrichment in biscuit production, in order to diversify its use; since it still remains an underutilized raw material in Ghana.

Marcadores de estrés oxidativo en hipertensión leve

Introducción: La hipertensión es un factor de riesgo cardiovascular y en 90% de los casos se desconoce el mecanismo que la inicia. Recientemente, se considera que la hipertensión es un síndrome de anormalidades metabólicas y estructurales, en el que las especies reactivas derivadas del oxígeno (EROs) juegan un papel fisiopatológico preponderante en su desarrollo. Objetivo: Determinar los niveles séricos de zinc, selenio y magnesio en personas normotensas e hipertensas. Asimismo, valorar la actividad de la enzima superóxido dismutasa (SOD) y los niveles de sustancias reactivas al ácido tiobarbitúrico (TBARS) en ambos grupos de estudio. Diseño: Estudio analítico observacional, tipo casos y controles. Lugar: Centro de Investigación de Bioquímica y Nutrición, Universidad Nacional Mayor de San Marcos. Material biológico: Sangre de pacientes normotensos y con hipertensión leve. Intervenciones: Se obtuvo las muestras de sangre de 20 pacientes normotensos y 20 con hipertensión leve, con edades entre 50 y 60 años, después de un ayuno de 12 horas, realizándose el estudio en suero y sangre total. Principales medidas de resultados: Variación de niveles de TBARS, oligoelementos (Se, Zn y Mg), medición de actividad de SOD eritrocitario. Resultados: En el grupo de hipertensos, se obtuvo incremento significativo de magnesio y TBARS y disminución significativa de zinc y de la actividad de SOD. Conclusiones: Se demuestra el compromiso del estrés oxidativo en pacientes con hipertensión leve. La hipermagnesemia podría explicarse por el daño a los elementos formes de la sangre.

Quality of 4-hourly ejaculates - levels of calcium and magnesium

A four-hourly ejaculation study was conducted in which eleven normal healthy subjects participated. Five of them discontinued after submitting three samples. One alone was present for submission at the end of 16h (fifth ejaculate), which was his last submission. Physical exhaustion was the sole reason for all participants for their discontinuation from the study. The result showed a decrease in semen volume and sperm count from first to last ejaculate. The increase in motility was probably due to reduction in exposure time to sperm motility inhibitory factors. In general, total motile spermatozoa as well as actively motile spermatozoa progressively increased from first to last ejaculate at the cost of sluggish spermatozoa. A significant increase in seminal plasma calcium and magnesium was seen as well as a significant increase in magnesium inside the cell from the first to the fourth ejaculate. Considering the quality of semen, which was good in sperm count and excellent in motility, calcium and magnesium may be helpful in cleaning motility inhibitory factors of spermatozoa.

Inhibition of urinary calculi—a spectroscopic study

AbstractAlthough herbal medicine is widely employed in inhibition of urinary calculi as an alternative and complementary curative method, the lack of detailed scientific studies that could provide insights into this complex process weakens its validity. The present work targets multitechnique spectroscopic investigations by Raman, infrared absorption, X‐ray photoelectron spectroscopy (XPS), and photoluminescence on the effects of the herb Rotula Aquatica Lour (RAL) on the growth of synthetically prepared magnesium‐based calculi. In addition to the standard magnesium phosphate‐based sample, two other samples were prepared with incorporation of 1 and 2wt% RAL herbal extract. Both, Raman and infrared data show a newberyite structure for the crystals without and with inhibitor. The XPS measurements reveal an unexpected presence of Zn in the sample with bfRAL inhibitor, which, as suggested in the literature, may initiate rapid stone formation, and consequently, contribute to the inhibition process. Furthermore, the existence of metallic Zn can explain the reflectance of the incident light observed in the infrared transmission studies of the unground crystals. A significant increase in magnesium with addition of herbal extract is observed in the XPS data. Also, evidence for MgO binding between the inhibitor and the phosphate units of urinary calculus is found in XPS and Raman results. Similarity between our photoluminescence measurements and those of in vivo chlorophyll a corroborates to provide additional evidence of Mg‐related inhibition. Copyright © 2009 John Wiley &amp; Sons, Ltd.

Pathogenesis of chest wall abnormalities--electron microscopy studies and trace element analysis of rib cartilage

In 71 patients with chest deformity (Group B) and in 43 patients who underwent thoracotomy due to heart disease (Group BN), cartilage of the ribs was removed intraoperatively. Analyses of trace elements showed a highly significant decrease in zinc, coupled with a significant increase in magnesium and calcium in Group B. Electron microscope studies in the cartilage of patients with chest deformity revealed chondrocytes with a normal structure only in some parts, but many degenerative altered chondrocytes with vacuoles of fat and osmiophilic depositions, as well as atypical fibrils and so-called "long-spacing collagen".

Ultrastructure of juxtaglomerular cells correlated with biochemical parameters in a hibernator

1. 1. Ultrastructural features of juxtaglomerular cells have been correlated with plasma and kidney analyses from non-hibernating, hibernating and awakening ground squirrels. 2. 2. Juxtaglomerular cells in kidneys from hibernating animals show signs of increased activity. 3. 3. Plasma samples from hibernating animals show a significant increase in magnesium. 4. 4. Kidney analyses from hibernating animals, show glycogen increases and lactate and inorganic phosphate decrease significantly. Adenosine triphosphate remains the same. 5. 5. Maintenance of high-energy phosphates in the hibernating kidney is essential to maintaining sodium transport and osmotic pressure. This coupled with a functional renin-angiotensin system regulates water and electrolyte balance.