The performance of twelve men was measured during a 9-week study. Six of the men received placebos and six received 2 g of magnesium and potassium salts of aspartic acid (Spartase) daily during 5 weeks of therapy. There was no significant difference in metabolic rate and RQ between the control or aspartate supplemented groups during moderate exercise and the recovery period after moderate exercise. Differences in other factors, such as maximum breathing capacity, vital capacity, breath-holding time, etc., were also nonsignificant. A few significant differences appeared between groups for the neuromuscular excitability values, which because of their erratic pattern probably were due to chance. Under the stresses imposed in this study there seemed to be no convincing evidence of the beneficial effects of aspartate therapy. exercise; neuromuscular fatigue; metabolic rate, respiratory measurements and physical fitness index under aspartate therapy; ergogenic drugs Submitted on May 8, 1963
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