The integration of Operations Research (OR) principles into Quality Management Engineering constitutes a powerful strategy for enhancing product and service quality throughout the entire lifecycle. This synergistic relationship unfolds within the context of OR, a discipline rooted in mathematical models, analytical methods, and decision-making tools, originally developed during World War II. Quality Management Engineering, built upon principles like Total Quality Management (TQM) and Six Sigma methodologies, systematically combines engineering principles with quality management techniques to ensure consistent high-quality outcomes. This interdisciplinary approach proves particularly critical in industries emphasizing precision, reliability, and efficiency. The application of OR in Quality Management Engineering encompasses diverse facets, including process optimization, supply chain management, quality control, root cause analysis, resource allocation, and risk management. This integration leverages mathematical modelling, statistical analysis, and optimization techniques to systematically improve and sustain product and process quality. Emphasizing continuous improvement, the collaboration integrates Lean principles, waste reduction strategies, and a commitment to ongoing assessment. The partnership between OR and Quality Management Engineering remains adaptable to changing business landscapes, addressing human factors, environmental considerations, and the era of data-driven decision-making. This abstract highlights the evolution of OR and its contribution to creating a structured, data-driven, and analytical approach to decision-making in quality management. Ultimately, this integration shapes efficient, resilient, and quality-focused organizations, positioning them for success and competitiveness in dynamic industries.