Chemical Side Effects Research Articles

Mechanism analysis of toxic and side effects of chemicals on human body

The exposure of the human body to different chemical substances poses a critical hazard to public well-being. Chemical toxicity is fundamentally ascribed to the disturbance of typical biological processes and can result in unfavorable health results. Understanding the components by which chemical substances apply their harmful impacts is vital for surveying and moderating these dangers. In this research, it will discuss the different routes of exposure, such as inhalation ingestion and dermal contact through which chemicals can enter the body. This research investigates the complex instruments at the atomic and cellular levels, counting oxidative stretch DNA harm and disturbance of enzymatic pathways by which harmful impacts are actuated. The evaluation of chemical toxicity includes a range of toxicological considerations, including acute and chronic toxicity tests, genotoxicity measures, and carcinogenicity evaluations. The development of reliable toxicity evaluation strategies, such as in vitro and in silico models, plays an urgent part in predicting the adverse impacts of chemical substances. Administrative systems and hazard evaluation techniques are discussed to guarantee peoples and the environments security. A comprehensive understanding of the components and assessment of poisonous side impacts is essential for defending open health and minimizing the hindering effects of chemical exposure.

A Clinical Evaluation of Dantaraksha (An Ayurvedic Tooth Powder) in the Management of Chronic Periodontitis

Chronic periodontitis is the inflammation of the periodontal tissue caused due to the accumulation of dental plaque. If untreated it will lead to progressive attachment loss, bone loss & ultimately tooth loss. It can be correlated to Dantavestaka in Ayurveda. Acharya Sushruta says it manifests due to Dusta Shonita (Vitiated blood). It has symptoms like bleeding gums, pus discharge & mobility in teeth. Conventional periodontal therapy consists of mechanical debridement that is scaling & root planning. Ayurvedic medication Dantaraksha – Tooth powder has been used as an adjunct in the management of chronic periodontitis to avoid the side effects of chemicals. Objective: To evaluate the efficacy of Dantaraksha – Tooth powder, as an adjunct to scaling & root planning in Chronic Periodontitis patients. Material and methods: 40 patients selected for the study were equally divided in two groups: Group A – Only Scaling and Root planning, Group B – Scaling and root planning followed by application of Dantaraksha tooth powder to the gums & teeth, twice daily, and massaging the same on gums & teeth gently with finger. Plaque index, gingival bleeding index scores and probing pocket depth were evaluated at baseline & after one month of treatment. Results: The results show statistically significant difference between Groups A vs B. By looking at the mean value of Group A & Group B it was found that Group B gingival index, plaque index & probing pocket depth was significant over Group A. Conclusion: Dantaraksha powder is effective as an adjunct in the management of chronic periodontitis patients when compared to conventional scaling & root planning alone.

Inoculated Traps, an Innovative and Sustainable Method to Control Banana Weevil Cosmopolites sordidus in Banana and Plantain Fields

The banana weevil Cosmopolites sordidus (Germar) is the most important insect pest of banana and plantain (Musa spp.). The larvae by its trophic activities bore into the corm, present roots are destroyed and the emergence of new roots is delayed, reducing nutrient uptake and weakening the stability of the plant. Attacks in newly planted banana stands can lead to crop failure. In established fields, weevil damage can result in reduced bunch weights, mat die-out and shortened stand life. Damage and yields losses tend to increase with time. Banana weevil has been implicated as a primary factor contributing to the decline and disappearance of East African highland cooking banana from its traditional growing areas in central Uganda. Control measures are essentially based on the use of chemicals. Adult resistance, environnemental pollution, most toxicity to famers also to consumers, and its effect on non target insect were negative side effects of chemicals. Alternative sustainable methods (use of parasitoids, predators, mass trapping with or without pheromon) were experimented, but results were few interest. Biological control using entomopathogenic fungi within genera Metarhizium and Beauveria bassiana were performed. Although promise results are shown in preliminary studies, efficient delivery systems still need to be developed. Research protocols for the development of a microbial control program of banana weevil using Metarhizium has focused in Cote d’Ivoire since 2008. It based on inoculated disk on stump traps (culombia trap), pheromon traps, pseudostem traps including its gregariousness to disseminate inoculum among weevils for sanitation of established field and biorationals. So these methods appear to be the promise ones significantly least fastidious and economic.