Si Groups Research Articles

Accuracy and primary stability of tapered or straight implants placed into fresh extraction socket using dynamic navigation: a randomized controlled clinical trial.

To compare the accuracy and primary stability of tapered and straight implants undergoing immediate implant placement with dynamic navigation. Patients with compromised anterior teeth in maxilla were recruited and allocated randomly into (1) tapered implant group (TI group) and (2) straight implant group (SI group). Implants were inserted into fresh sockets with dynamic navigation. Three-dimensional platform deviation, apex deviation, angular deviation, insertion torque value (ITV) and implant stability quotient (ISQ) were recorded. Twenty patients with 20 implants were included. The overall platform, apex, and angular deviation were 0.87 ± 0.35mm, 0.81 ± 0.34mm, and 2.40 ± 1.31°, respectively. The accuracy was 0.86 ± 0.26mm, 0.76 ± 0.33mm, and 2.49 ± 1.54° for TI, and 0.89 ± 0.44mm, 0.88 ± 0.36mm, and 2.31 ± 1.01° for SI, with no significant difference (p = 0.85, 0.45, 0.76). Sagittal root position classification (SRP) class I may obtain greater error in numerical values in straight implants (0.97 ± 0.47mm vs. 0.6 ± 0.16mm, 0.92 ± 0.36mm vs. 0.73 ± 0.36mm, 2.48 ± 1.19° vs. 1.71 ± 0.14°). The overall ISQ was 60.74. ISQ was 60.48 for TI and 60.96 for SI, with no significant difference. Acceptable ITV (> 15Ncm) was achieved in most of the included patients (SI 7/10, TI 9/10). High accuracy and primary stability of immediate implant placement could be achieved both in tapered and straight implants with dynamic navigation systems. Tapered and straight implants did not reach a consensus on which was better in immediate implant regarding to accuracy and primary stability. Our study demonstrated implant macrodesign did not affect accuracy and primary stability in immediate implant using dynamic navigation.

Visual assessment between phacoemulsification and small incision with 5.2mm non-foldable intraocular lens implant.

Objective: To compare visual assessment between phacoemulsification and small incision with 5.2mm non-foldable intraocular lens implant. Study Design: Experiential Study. Setting: Institute of Ophthalmology, Liaquat University Hospital Jamshoro, Period: September 2019 to August 2020. Material & Methods: We performed cataract surgeries using the non-foldable intraocular lens in 100 patients. Two techniques were performed, dividing patients equally into Phaco (Group-A) and SI (Group-B) cataract surgery. The outcomes of both were analyzed uncorrected visual acuity and complications. Results: Of the total 50 patients who underwent phacoemulsification, 55% were male and 45% females in Group-A while Group B (SI surgery) were 45% were male and 35% were female. The intra-operative success rate was 90% in Phaco group and 74% in SI group. In comparison, small Incision group had 10% of patients had difficulty in capsulorhexis, 8% in posterior capsular rupture, 6% in zonular dialysis, 2% iridodialysis, and 0% showing nucleus drip with all complications being higher than in Phaco Group except for nucleus drip (2% vs. 0%). Although, post-operatively, individually groups have similar complications with no notable difference seen, yet astigmatism was lesser in Group A than in Group B. Conclusion: Both techniques showed similar outcomes in the uncorrected visual acuity; however, astigmatism and complication rates were lesser in the phacoemulsification study group.

Quantitative contrast-enhanced ultrasound for the differentiation of kidney allografts with significant histopathological injury.

To identify specific quantitative contrast-enhanced ultrasound (CEUS) parameters that could distinguish kidney transplants with significant histopathological injury. Sixty-four patients were enrolled in this prospective observational study. Biopsies were performed following CEUS and blood examination. 28 biopsy specimens had minimal changes (MC group), while 36had significant injury (SI group). Of these, 12had rejection (RI group) and 24 non-rejection injury (NRI group). In RI and NRI groups, temporal difference in time to peak (TTP) between medulla and cortex (ΔTTPm-c) was significantly shorter compared to the MC group (5.77, 5.92, and 7.94s, P=0.048 and 0.026, respectively). Additionally, RI group had significantly shorter medullary TTP compared to the MC group (27.75 vs. 32.26s; P=0.03). In a subset of 41 patients with protocol biopsy at 1-year post-transplant, ΔTTPm-c was significantly shorter in the SI compared to the MC group (5.67 vs. 7.67s; P=0.024). Area under receiver operating characteristic curves (AUROCs) for ΔTTPm-c was 0.69 in all patients and 0.71 in patients with protocol biopsy. RI and NRI groups had shorter ΔTTPm-c compared to the MC group. AUROCs for both patient groups were good, making ΔTTPm-c a promising CEUS parameter for distinguishing patients with significant histopathological injury.

Effects of miR-21 Mediating Nerve Cell Adhesion Molecule (NCAM) and Glial Cell-Line Derived Neurotrophic Factor (GDNF) Signals on the Proliferation and Apoptosis of Lung Cancer Cells

Our study assessed the effect of miR-21 mediating Nerve Cell Adhesion Molecule (NCAM) and Glial Cell-line Derived Neurotrophic Factor (GDNF) on the proliferation and apoptosis of lung cancer cells. Lung cancer cell-line H460 cells were grouped as Lung cancer group (LC group) (normal cultivation); Mimic group (SI group) which was transfected with 120 nmol/L miR-21 mimics and liposomes; Inhibitor group (IN group) (transfection of miR-21 inhibitor and liposomes) followed by analysis of cell apoptosis by Hoechst 33258 staining, GDNF level by immunohistochemistry, miR-21 level by qRT-PCR, cell proliferation by CCK-8 and NCAM level by western blot. miR-21 content was significantly increased in SI group, indicating a successful transfection. The nucleus shrinkage rate in IN group and LC group was higher than SI group (P <0.05) and IN group had highest number of apoptotic cells, lowest cell proliferation and NCAM level among three groups (P <0.05). SI group showed significantly higher positive GDNF staining than IN and LC group (both P <0.05). miR-21 promotes H460 cell proliferation and inhibits cell apoptosis by upregulating NCAM and GDNF.

SI Group sells industrial resin business to ASK Chemicals

SI Group sells industrial resin business to ASK Chemicals

Comparison between Single- and Double-Injection Technique for Ultrasound-Guided Supraclavicular Block: A Randomized Controlled Study

Background: The supraclavicular approach to brachial plexus block is a commonly employed regional anesthesia technique for providing surgical anesthesia and postoperative analgesia for patients undergoing upper limb fractures. With ultrasound (US) guidance, the success rate of the block is increased, and complications like pneumothorax and vascular puncture are minimized. The block can be performed using single injection at the corner pocket or double injection, that is, half of the drug at the corner pocket and the remaining half at the cluster of brachial plexus divisions. Methods: After institutional ethics committee approval, we randomized 40 patients scheduled with fractures for elective upper extremity surgery under US-guided supraclavicular brachial plexus block. Twenty patients received 30 mL of local anesthetic at the corner pocket (group SI), and 20 patients received 30 mL of local anesthetic using the dual-injection technique in divided doses (group DI). Demographic data, time to block performance, time to sensory and motor block, total anesthesia-related time (TART), block success, and failure were compared between both groups. Results: The demographic data were comparable between both groups. The DI group had a significantly faster onset than the SI group (p = 0.0172). There was a statistically significant lesser performance time in group SI than in group DI (p < 0.034). The sensory and motor block achieved was comparable between both groups. Conclusion: The success rates in both the SI and DI techniques are comparable. The DI technique results in a faster onset and hence a shorter TART; however, it may not be clinically relevant.

Effects of MicroRNA-22 (miR-222) on Non-Small-Cell Lung Carcinoma (NSCLC) Cells Apoptosis and Proliferation Through Protein Kinase B/Mammalian Target of Rapamycin (AKT/mTOR) Signaling Pathway

Our study investigated miR-222’s effect on NSCLC apoptosis and proliferation. H1650 cells were assigned into NSCLC group, SI group and IN group followed by analysis of Akt-mTOR protein content, cell apoptosis and proliferation, and miR-222 expression by Western blot, Hoechst 33258 fluorescence staining, qRT-PCR, cck-8, and immunohistochemistry miR-222 expression was lowest in IN group and highest in SI group (P &lt; 0.05). The nucleus shrinkage rate in IN group and NSCLC group was significantly higher than that in SI group (P &lt; 0.05) with NSCLC group showed more cells apoptosis than IN group (P &lt; 0.05). The SI group had significantly higher OD value than IN group and NSCLC group (P &lt; 0.05) with NSCLC group having significantly higher OD value than IN group (P &lt; 0.05). The Akt-mTOR and p-Akt/p-mTOR expression was lowest in IN group and highest in SI group (P &lt; 0.05) with lower level in IN group than NSCLC group (P &lt; 0.05). The number of positive Akt-mTOR of H1650 cells was highest in SI group while lowest in IN group (P &lt; 0.05). The decreased miR-222 expression in NSCLC can promote cancer cell apoptosis and inhibit lung cancer development, which may be via down-regulating Akt-mTOR signaling.

High Eyelid Crease Deformity in Asians: A Clinical Evaluation and Corrective Strategies

The aim of this study was to describe the manifestations of post-blepharoplasty high eyelid crease patients and to propose steps of clinical evaluation and corrective operations. High eyelid crease patients were categorized into 3 groups, including pre-existing ptosis (PP), surgical induced levator compromised (SI), and high eyelid crease alone (HC), based on their MRD1 and signs of compromised levator muscle. The primary outcomes were the type and success rate of the operative techniques. The secondary outcomes were the complications. A total of 131 patients were enrolled, 7 males and 124 females, with an average age of 39.7 years. The mean scar height in the HC, SI, and PP groups were 10.4 ± 2.2, 12.8 ± 2.6, and 9.0 ± 2.0 mm, respectively. The scar height in the SI group was statistically differently higher than the other groups (mean: 1.7 mm, 95% CI: [0.91, 2.43]; P &lt; 0.001). In total, 117 eyes of 67 patients underwent corrective operations with significant lower eyelid fold height and an 83.6% success rate. There were 6 re-operation eyes, 5 in the SI group and 1 in the PP group. High blepharoplasty incision scar can lead to surgical induced levator compromise and ptosis. Systematical evaluation and optimal corrective operations are needed to achieve targeted outcome.

Skin Immune Response of Immunocompetent and Immunosuppressed C57BL/6 Mice After Experimental Subcutaneous Infection Caused by Purpureocillium lilacinum.

Hyalohyphomycosis is a fungal infection characterized by the presence of a hyaline mycelium in the host. It is caused by several agents, such as Purpureocillium lilacinum. Our study aimed to evaluate some cell subsets and inflammatory markers involved in the in situ immune response to subcutaneous hyalohyphomycosis by P. lilacinum in C57BL/6 murine models. The fungal isolate was inoculated in mice randomly distributed in immunocompetent/infected (CI) and immunosuppressed/infected (SI) groups. Mice were evaluated on days 1, 3, 5, and 7 after inoculation. Histopathological studies showed several lesions in the site of infection as well as the formation of multifocal and mixed inflammatory infiltrates, which differed between the CI and SI groups. This analysis also revealed conidia and hypha-like structures in subcutaneous tissues of mice of both groups. The immunohistochemical analysis showed lower percentages of macrophages and neutrophils in the SI group compared to those in the CI group. Moreover, the intensity of interleukin (IL)-1β and nitric oxide synthase 2 production by cells of immunosuppressed mice was discreet, compared to immunocompetent mice that ranged from moderate to intense over time. The quantitative interference of dexamethasone in the response to the fungus was also demonstrated. We concluded that our results can be useful not only to broaden the knowledge on P. lilacinum but also, based on this host–parasite relationship, to contribute to the understanding of the mechanisms of infection.

Study on ageing characteristics and evaluation methods of RTV silicone rubber in high humidity area.

Due to high humidity, the ageing of room temperature vulcanized silicone rubber (RTV) has been a serious problem in Southwestern China. In order to solve the problem of RTV life prediction, the aging classification method was established by analyzing the microtopography of RTV samples in this paper. Besides, the comprehensive analysis of RTV element content, partial element content ratio, and major chemical groups of RTV samples in each aging level were conducted. It is found that as the ageing level increases, the element contents of C, Si, O, Al change accordingly and the ratio of C:Si drops from 2.39 to 1.54, and absorption peaks of the chemical groups of Si-(CH3)2, Si-O-Si, Si-CH3 and C-H in CH3 decrease. This work can enrich the investigation of RTV, and may provide useful reference for performance evaluation and replacement of RTV in substations.

SI Group slates US polymer additives

SI Group plans to spend more than $50 million across three sites in North America to boost output of phenolic antioxidants for plastics. The firm says the investment demonstrates its commitment to the expanding US chemical market and to sectors such as food packaging, automotive, construction, and adhesives. Based in Schenectady, New York, and privately owned, SI says its goal is to be the global additive powerhouse.

SI Group plans polymer additives in the US

SI Group plans polymer additives in the US

Comparison of short-term surgical outcomes using da Vinci S, Si and Xi Surgical System for robotic gastric cancer surgery

When compared with the second/third generation da Vinci S/Si, the fourth generation Xi surgical system may allow for greater efficiency and result in shorter operation times during robotic gastrectomy (RG) for gastric cancer (GC). We directly compare surgical outcomes between the conventional S/Si and the newer Xi robotic platform for the treatment of GC. This is a single-center retrospective study of 148 consecutive patients with GC who underwent RG. Of these patients, 20 patients were treated with the S, 30 patients with the Si, and 98 patients with the Xi. The overall operation time was significantly longer in the S group (386.5 min) than in the other groups (Si group: 292 min; Xi group: 297 min) (S vs. Si: P = 0.010; S vs. Xi: P = 0.001). We observed no difference, however, between the newer Xi and Si systems in operation time. Intraoperative blood loss was similar across the three groups. The overall postoperative complication rate in the Xi group (8.2%) was lower than that of the S group (10%) and the Si group (13.3%), but the difference was not significant. The newer Xi system did not provide significant intraoperative or early postoperative advantages over the Si system.

Read speech voice quality and disfluency in individuals with recent suicidal ideation or suicide attempt

Individuals that have incurred trauma due to a suicide attempt often acquire residual health complications, such as cognitive, mood, and speech-language disorders. Due to limited access to suicidal speech audio corpora, behavioral differences in patients with a history of suicidal ideation and/or behavior have not been thoroughly examined using subjective voice quality and manual disfluency measures. In this study, we examine the Butler-Brown Read Speech (BBRS) database that includes 20 healthy controls with no history of suicidal ideation or behavior (HC group) and 226 psychiatric inpatients with recent suicidal ideation (SI group) or a recent suicide attempt (SA group). During read aloud sentence tasks, SI and SA groups reveal poorer average subjective voice quality composite ratings when compared with individuals in the HC group. In particular, the SI and SA groups exhibit average ‘grade’ and ‘roughness’ voice quality scores four to six times higher than those of the HC group. We demonstrate that manually annotated voice quality measures, converted into a low-dimensional feature vector, help to identify individuals with recent suicidal ideation and behavior from a healthy population, generating an automatic classification accuracy of up to 73%. Furthermore, our novel investigation of manual speech disfluencies (e.g., manually detected hesitations, word/phrase repeats, malapropisms, speech errors, non-self-correction) shows that inpatients in the SI and SA groups produce on average approximately twice as many hesitations and four times as many speech errors when compared with individuals in the HC group. We demonstrate automatic classification of inpatients with a suicide history from individuals with no suicide history with up to 80% accuracy using manually annotated speech disfluency features. Knowledge regarding voice quality and speech disfluency behaviors in individuals with a suicide history presented herein will lead to a better understanding of this complex phenomenon and thus contribute to the future development of new automatic speech-based suicide-risk identification systems.

Influence of Non-Thermal Atmospheric Pressure Plasma Treatment on Retentive Strength between Zirconia Crown and Titanium Implant Abutment.

The aim of this study is to investigate the effect of non-thermal atmospheric pressure plasma (NTP) on retentive strength (RS) between the zirconia crown and the titanium implant abutment using self-adhesive resin cement. Surface free energy (SFE) was calculated on 24 cube-shaped zirconia blocks, and RS was measured on 120 zirconia crown-titanium abutment assemblies bonded with G-CEM LinkAce. The groups were categorized according to the zirconia surface treatment as follows: Control (no surface treatment), NTP, Si (Silane), NTP + Si, Pr (Z-Prime Plus), and NTP + Pr. Half of the RS test assemblies were aged by thermocycling for 5000 cycles at 5–55 °C. The SFE was calculated using the Owens-Wendt method, and the RS was measured using a universal testing machine at the maximum load until failure. One-way analysis of variance (ANOVA) with post-hoc Tukey honestly significant difference (HSD) was performed to evaluate the effect of surface treatments on the SFE and RS. Independent sample t-test was used to compare the RS according to thermocycling (p < 0.05). For the SFE analysis, the NTP group had a significantly higher SFE value than the Control group (p < 0.05). For the RS test, in non-thermocycling, the NTP group showed a significantly higher RS value than the Control group (p < 0.05). However, in thermocycling, there was no significant difference between the Control and NTP groups (p > 0.05). In non-thermocycling, comparing with the NTP + Si or NTP + Pr group, there was no significant difference from the Si or Pr group, respectively (p > 0.05). Conversely, in thermocycling, the NTP + Si and NTP + Pr group had significantly lower RS than the Si and Pr group, respectively (p < 0.05). These results suggest that NTP single treatment for the zirconia crown increases the initial RS but has little effect on the long-term RS. Applied with Silane or Z-Prime Plus, NTP pre-treatment has no positive effect on the RS.

The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR.

We investigated the positive effect of silibinin after IV administration as silibinin-hydroxypropyl-β-cyclodextrin lyophilized product, by measuring gene expression and liver tissue protein levels of tumor necrosis factor-α, interleukin-6, monocyte chemoattractant protein-1, matrix metalloproteinases matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases-2. 63 Wistar rats of age 13.24±4.40 weeks underwent ischemia/reperfusion (I/R) injury of the liver. The animals were randomized into three groups: Sham (S; n = 7); Control (C; n-28); silibinin (Si; n-28). The C and Si groups underwent 45 min ischemia. Si received silibinin-hydroxypropyl-β-cyclodextrin intravenously immediately before reperfusion at a dose of 5 mg/kg. Both groups were further divided into 4 subgroups, based on euthanasia time (i.e., 60, 120, 180 and 240 min). qRT-PCR results confirmed the statistically significant reduction of the expression of the pro-inflammatory factors at 240 min after I/R injury (tumor necrosis factor-α: P < 0.05; MCR1: P < 0.05) and matrix metalloproteinases (matrix metalloproteinases 2: P < 0.05; matrix metalloproteinases 3: P < 0.05) and the increase of tissue inhibitor of matrix metalloproteinases-2 in liver tissue in the Si group. Moreover, results of immunohistochemistry levels confirmed that at 240 min pro-inflammatory factors (tumor necrosis factor-α: P < 0.05; MCR1: P < 0.05) and matrix metalloproteinases ( matrix metalloproteinases 2: P < 0.05; matrix metalloproteinases 3: P < 0.05) had a statistically significantly lower expression in the Si group while tissue inhibitor of matrix metalloproteinases-2 had a higher expression. Silibinin may have a beneficial effect on the protection of the liver.

Doping effects of Pd2+ on physicochemical and biomechanical properties of calcium silicate in nano-regime towards treating osteoporotic bone

Fully dense biphasic calcium silicates with improved biomechanical behavior were fabricated via mechanothermal method followed by the conventional sintering process. The effects of dopant concentration on the phase composition, structural evolution, and mechanical properties of palladium-doped calcium silicates (PCSs) were investigated. The results showed that the coalescence of nanoparticles, coarsening of particles, and the formation of large agglomerates occurred during the mechanothermal reactions. Attenuated total reflection (ATR) spectroscopy spectra of the PCSs represented the characteristic bands of the calcium silicates, including the bending mode of Si–O–Si and O–Si–O, the stretching vibration of O–Si–O group, the stretching mode of Si–O–Ca, as well as the symmetrical stretching mode of Si–O–Si group. The results of the Rietveld refinement indicated that the phase compositions and structural features noticeably affected by the dopant concentration so that the phase fraction (PF) of Wollastonite-1A and Pseudowollastonite was 0.318 ± 0.035 and 0.526 ± 0.025 in the case of undoped calcium silicate (PCS0), which respectively reached 0.411 ± 0.021 and 0.589 ± 0.021 for the Pd-doped calcium silicate (PCS20). Comparing with the PCS0, the Vickers hardness of the consolidated PCS20 increased by ~79%. From the biomineralization analysis, the surface of the consolidated sample was covered by the bone-like apatite after soaking in a simulated body fluid (SBF) for 2 weeks.

Enhanced friction and shock sensitivities of hexachlorodisilane hydrolyzed deposit mixed with KOH

In this work, the effects of potassium hydroxide (KOH) on friction and shock sensitivity of the hexachlorodisialne hydrolysis products were studied. A wide range of KOH content, from 0.02 to 21.5 wt%, in the mixture of KOH and HCDS hydrolyzed deposit was prepared by mixing the deposit with aqueous KOH solution and dried in glovebox. The lowest impact energy (LIE) and lowest friction force (LFF) were determined by BAM fall-hammer and friction test apparatus, respectively. It was found that both shock and friction sensitivities increased with an increase in the KOH content in the HCDS hydrolyzed deposit. In particular, the LIE and LFF decrease from 6 J to 326 N of the original deposit to less than 0.125 J and 7 N for deposit with 0.03 and 0.3 wt% KOH. Differential scanning calorimetry studies showed that a new exothermic peak was observed between 80 °C and 150 °C which is also accompanied by evolution of hydrogen. It is proposed that, the presence of KOH results in the formation of Si–Si–OK groups leading to the weakening of the neighboring Si–Si bonds. Any mechanical impact or friction will lead to the cleavage of the unstable Si–Si bonds and subsequently initiate a fast chain oxidation of adjacent Si–Si and Si–OH bonds to form more Si–O–Si groups, releasing H2 gas and heat. Recommendations were given for handling and disposing of these explosive deposits.

Maternal selenium deficiency during gestation is positively associated with the risks for LBW and SGA newborns in a Chinese population.

Maternal selenium (Se) deficiency is associated with some adverse pregnant outcomes. However, it remains controversial whether maternal Se deficiency during gestation enhances the risks for low-birth-weight (LBW) and small-for-gestational-age (SGA) newborns. For our cohort study, total 3133 mother-and-infant pairs were selected. Maternal serum Se concentration was detected by graphite furnace atomic absorption spectrometry. According to international references for maternal serum Se concentration, subjects were divided into Se deficiency (<45.0 μg/L), Se insufficiency (45.0-94.9 μg/L) and Se sufficiency (≥95.0 μg/L). There was a positive relation of maternal serum Se concentration in gestation and neonatal birth weight. Further analysis showed that the risks for LBW and SGA in SD group were significantly higher than that in SI and SS group, the adjusted ORs for LBW and SGA newborns were 1.87 (95%CI: 1.02, 3.45; P = 0.04) and 1.47 (95%CI: 1.07, 2.02; P = 0.02) in SI group, and 3.92 (95%CI: 2.03, 7.57; P < 0.001) and 2.77 (95%CI: 1.92, 4.02; P < 0.001) in SD group compared to SS group. In different gender subgroup, positive relations were observed between maternal Se deficiency and the risk for LBW girls, as well as the risks for both SGA girls and boys. Maternal Se deficiency in gestation was positively associated with the risk for LBW girls, as well as the risks for both SGA girls and boys.

Radical prostatectomy technique in the robotic evolution: from da Vinci standard to single port\u2014a single surgeon pathway

To describe perioperative outcomes following robot-assisted prostatectomy performed by a single surgeon during transitions between da Vinci standard/Si/Xi and the single port. Perioperative data were retrospectively evaluated of the first 40 consecutive robot-assisted radical prostatectomies performed by a single surgeon using the da Vinci standard, Si, Xi and single port. A total of 160 patients were included. We matched standard vs Si (Match 1), Si vs Xi (Match 2) and Xi vs single port (Match 3) cohort. Mann–Whitney and Fisher’s tests were used to test the difference among the groups. Univariate and multivariate logistic regression analyses were adopted to evaluate the predictors of overall and major complications. Single-port procedures in Match 3 showed significant shorter median operative time than Xi. Both Si and single-port groups showed significantly less median blood loss, a shorter median length of stay, respectively, than standard group in Match 1 and than Xi group in Match 3. 1 standard group patient required conversion to open surgery for an unsolvable conflict of the robotic arms. No other intraoperative complications were noted. On univariate and multivariate analyses, the da Vinci platform model was not a predicting factor of major complications (Clavien–Dindo ≥ 3). We described how technological progress impacted peri and postoperative outcomes during transitions between robotic surgical platforms for radical prostatectomy. In particular, the technological improvements associated to the increased surgeon’s expertise made the transition to the single port safe and effective when compared with previous platforms.