Short Vein Grafts Research Articles

Overcoming severe calcified lower extremity artery in lower limb salvage operation by using the Fogarty catheter and vein graft.

With severe vascular calcifications, vascular clamp application and utilizing the vessel for free flap recipient vessel becomes impossible. These obstacles can be overcome with the Fogarty catheter and vein graft. When unclampable artery was encountered intraoperatively, a vein graft was used to make a clampable recipient site for six diabetic foot patients (ages from 42 to 80). The end of the Fogarty catheter was inserted into the proximal end of the vein graft and the transected calcified vessel in sequence, and the balloon of the catheter was used as an intraluminal tourniquet. The remaining end of the vein graft was connected to the distal vessel with a vascular clamp. Five short vein graft revascularization for segmental arterial occlusion, one long vein graft for recipient artery elongation was done (lengths from 2 to 13.8cm). Three delayed, and two immediate anterolateral thigh flaps (sizes from 15 to 150 cm2 ) were performed, and one patient received vein graft revascularization surgery only. Postoperative vascular sonography of all six patients showed well-maintained patency. Minor flap marginal disruption occurred at two patients but healed with conservative care. Postoperative follow-up was done for 1-18 months (average 7.17). Limb salvage was achieved for five patients and all five free flaps survived. However, for one patient, arterial restenosis at popliteal artery a month later lead to major amputation. Using a Fogarty catheter and a vein graft may obtain perfect hemostasis during micro-anastomosis and achieve successful microvascular reconstruction in patients with severely calcified vessels.

Surgical Treatment of Complex Cerebral Aneurysms Using Interposition Short Vein Graft.

Cerebral revascularization strategies may become necessary in select patients who present with challenging cerebral aneurysms. In this study, we present the techniques of a moderate-flow extra-intracranial bypass using a short interposition vein graft and concurrent aneurysm management. The short interposition vein graft was used for the reconstruction of complex cerebral aneurysms in nine patients. In eight of them, the superficial temporal artery (STA) main trunk was used as a donor site for the anastomosis of a short interposition vein graft, and an extracranial vertebral artery (VA) was used in one case. The vein grafts were implanted into the M2 of the middle cerebral artery (MCA) for the adjunctive treatment of internal carotid artery (ICA) aneurysms in three patients, into the A3 of the anterior cerebral artery (ACA) in one patient, into the P2 of the posterior cerebral artery (PCA) for the adjunctive treatment of complex PCA aneurysms in three patients, into the P3 of the PCA for the adjunctive treatment of a basilar artery (BA) trunk giant aneurysm in 1 patient, and into the postero-inferior cerebellar artery (PICA) for the adjunctive treatment of the VA dissecting aneurysm in one patient. All of the bypasses were patent. Intraoperative flow measurements confirmed a moderate flow-carrying capacity of the short interposition short vein graft (30-70 ml; mean: 43 ml/min). The STA main trunk to proximal MCA/PCA bypass and the extracranial VA to PICA bypass using short interposition vein grafts can provide sufficient blood flow and may be a reasonable alternative to the conventional EC-IC bypass/high-flow bypass.

STA-MCA/STA-PCA Bypass Using Short Interposition Vein Graft.

Superficial temporal artery (STA) is the mainstay of donor vessels for extra-intracranial bypass (EC-IC bypass) in cerebral revascularization. However, the typically used STA frontal or parietal branch is not always adequate in its flow-carrying capacity. In the present study, we provide an update on an alternative strategy: the use of the STA main trunk as a donor vessel, with a short vein interposition graft. Seven patients in whom the STA main trunk was used as a donor site for anastomosis of a short interposition vein graft were included. The grafts were implanted into the M2 of the middle cerebral artery for adjunctive treatment of IC anterior wall blood-blister aneurysms in two patients, for revascularization of an internal carotid artery occlusion in one patient, into the P2/3 of the posterior cerebral artery (PCA) for adjunct treatment of complex PCA aneurysms in three patients and into the P3 of PCA for adjunct treatment of basilar artery (BA) trunk giant aneurysm in one patient. All the bypasses were patent. Intraoperative flow measurements confirmed a moderate flow-carrying capacity of the STA main trunk-interposition short vein graft (20-50 ml; mean 43 ml/min). The STA main trunk has a larger diameter than the distal branch; therefore, it would be expected to have a significantly higher flow capacity than its branches. STA main trunk to proximal MCA/PCA bypass using short interposition vein grafts can provide sufficient blood flow, and may be a reasonable alternative to ECA to MCA/PCA bypass using long vein grafts.

Scimitar syndrome in an infant with right lung hypoplasia, ventricular septal defect, and severe pulmonary hypertension

A 5-month-old boy was presented for surgical repair of scimitar syndrome associated with right lung hyperplasia, severe pulmonary hypertension, ventricular septal defect (VSD), and atrial septal defect. The calculated shunt fraction (Qp/Qs) was 3.1:1.0, pulmonary vascular resistance was 4.6, and the perfusion lung scan showed a marked decrease (11%) in right pulmonary blood flow. Surgical repair was performed through the right fourth intercostal space with the patient supine. The anomalous vein was divided and interposed with a short azygos vein graft, followed by closure of the VSD. Finally, the interposed azygos vein was anastomosed to the left atrium. Although pulmonary artery pressure was normalized at the 2-year follow-up, cardiac catheterization 6 months after the operation demonstrated right pulmonary vein obstruction.

An anatomic study for a modified technique for bypass of the external carotid artery to the proximal middle cerebral artery

We aimed to evaluate whether bypass of the external carotid artery (ECA) to the middle cerebral artery (MCA) can be established by a short saphenous vein graft in order to increase the anastomosis patency. The method was performed to ten adult cadaver sides. We described a modified technique for bypass of the ECA to the M2 segment of MCA. The diameters of the vessels and graft length were measured by using an electronic micrometer. The mean diameter of the superior, middle, and inferior trunks of the MCA with trifurcation were 1.7 +/- 0.15, 2.2 +/- 0.25, and 2.0 +/- 0.2 mm, respectively, whereas the mean diameter of the superior and inferior trunks of the MCA with bifurcation were 2.1 +/- 0.2 and 2.3 +/- 0.3 mm, respectively. The mean diameter of the ECA was 3.75 +/- 0.4 mm. The mean length of the saphenous vein graft was 71.5 +/- 3.9 mm. The high-flow ECA to proximal MCA bypass using a short venous graft can supply enough blood flow to establish cerebral revascularization with a straighter route.

A modified technique for bypass of the external carotid artery to the proximal posterior cerebral artery: An anatomical and technical study

Conclusions. Our results support the proposition that bypass between the external carotid artery (ECA) and proximal posterior cerebral artery (PCA) can be achieved by using a short saphenous venous graft. The diameters of the ECA and vein graft may provide an increased blood flow with a straighter course. This technique may be helpful for management of patients with vertebrobasilar insufficiency or those requiring a high volume blood flow to the posterior circulation. Objectives. We aimed to describe a modified technique using a short saphenous vein graft for bypass between the ECA and the PCA in order to use a small length of graft material and increase the patency of the anastomosis. Materials and methods. Ten sides of five cadavers were dissected bilaterally. After a frontotemporal craniotomy and zygomatic arch osteotomy, the middle cranial fossa was exposed. A hole located approximately 2–3 cm posterolateral to the foramen rotundum was created extradurally. The sylvian fissure and the interpedincular and ambient cisterns were opened. The proximal P2 segment of the PCA was identified. The ECA was found through a cervical incision. A short interposition saphenous vein graft was conducted to pass just behind the ramus mandible to the infratemporal fossa. The bypass between the ECA and P2 segment of the PCA was performed by using a short saphenous vein graft. The diameters of the ECA, P2 segment of PCA and both ends of the saphenous vein graft and its length were measured using an electronic micrometer. Results. The mean cross-clamping time of the PCA was 10.4±1.8 min. The mean diameters of the P2 segment of the PCA and ECA were 2.2±0.15 mm and 3.83±0.28 mm, respectively. The mean length of the saphenous vein graft was 88.8±3.8 mm.

A decade of experience with dorsalis pedis artery bypass: analysis of outcome in more than 1000 cases.

The purpose of this study was to review our experience over the last decade with the dorsalis pedis bypass for ischemic limb salvage in patients with diabetes mellitus. The study was a retrospective analysis of a computerized vascular registry and chart review. From January 10, 1990 to January 11, 2000, 1032 bypasses to the dorsalis pedis artery were performed in 865 patients (27.6% of the 3731 lower extremity arterial bypass procedures performed in that time period). Five hundred ninety-seven patients (69%) were male, with a mean age of 66.8 years. Ninety-two percent had diabetes mellitus. All procedures were done for limb salvage. Conduits included 317 nonreversed saphenous vein (30.7%), 273 in situ (26.4%), 235 reversed vein (22.8%), 170 arm vein (16.5%), 35 other vein (3.4%), and two polytetrafluoroethylene (0.2%) grafts. The inflow arteries were as follows: 294 common femoral (28.5%), 550 popliteal (53.2%), 114 superficial femoral (11%), and 74 other (7.2%). The mortality rate within 1 month of surgery was 0.9%, and 42 grafts (4.2%) failed in the same interval, although 13 were successfully revised. In a follow-up period that ranged from 1 to 120 months (mean, 23.6 months), primary patency, secondary patency, limb salvage, and patient survival rates were 56.8%, 62.7%, 78.2%, and 48.6%, respectively at 5 years and 37.7%, 41.7%, 57.7%, and 23.8% at 10 years. Both polytetrafluoroethylene grafts failed in less than 1 year. Primary graft patency was worse in female patients (46.5% female versus 61.6% male at 5 years; P <.009) but better in patients with diabetes (65.9% diabetes mellitus versus 56.3% non-diabetes mellitus at 4 years; P <.04). Saphenous vein grafts performed better than all other conduits with a secondary patency rate of 67.6% versus 46.3% at 5 years (P <.0001). Multivariate analysis showed that length of stay greater than 10 days and dorsalis pedis bypass for the surgical indication of previous graft occlusion were independently predictive of worse graft patency at 1 year and use of saphenous vein as conduit was predictive of better patency. Dorsalis pedis bypass is durable with a high likelihood of ischemic foot salvage over many years. Saphenous vein is the preferred conduit when available. Short vein grafts from distal inflow sites are possible in more than 50% of cases. These results justify the routine use of pedal arterial reconstruction for patients with diabetes with ischemic foot complications.

Infrapopliteal arterial occlusive disease in diabetics with critical foot ischaemia: The role of distal-origin bypass grafts

Background: The underlying cause for severe ischaemic foot lesions in diabetics is not infrequently a specific occlusion pattern exclusively involving infrapopliteal arteries. To attain limb salvage in this setting, since the early eighties short vein grafts originating from infragenicular arteries (distal-origin bypasses) were used to bypass the occluded crural vessels. This presentation describes our 15-year experience with this strategy and, in addition, assesses the outcome in patients suffering from end stage renal disease (ESRD). Patients and methods: Since May 1986, 135 diabetic patients underwent 143 so-called "distal-origin bypasses" in the presence of extended infrapopliteal arterial occlusions and critical foot ischaemia (rest pain 3, tissue loss 140). The mean age in this group was 70,1 years. 43 patients had impaired renal function including 16 cases with ESRD. Results: The 30 day mortality in our series was 2.1%. During the follow-up a total of 82 patients died, mainly from cardiovascular causes. Using life-table analysis, primary and secondary patency rates for these bypasses with distal graft origination were 90% and 97% at 30 days, 76% and 83% at 1 year and 46% and 51% at 7 years, respectively. The corresponding limb salvage rates for the whole group amounted to 94%, 80% and 64%. Comparing patients having normal or slightly impaired renal function with those diagnosed of ESRD, a significantly different result with higher limb salvage rates in favour of the first patient subgroup was noted after 5 years (77% vs. 39%; p = 0.0023). Conclusion: In our series, the importance of short vein grafts to avoid limb loss in diabetic patients with infrapopliteal artery occlusions and critical foot ischaemia has been well established. Despite poorer limb salvage rates achieved in ESRD-patients, our results suggest, that even these high risk patients should not be denied arterial reconstruction.

Tibioperoneal arterial lesions and critical foot ischaemia: successful management by the use of short vein grafts and percutaneous transluminal angioplasty.

In a substantial number of mainly diabetic patients isolated crural arterial lesions are found to be the underlying cause for severe ischaemic foot lesions. Without revascularisation, patients with this specific occlusion pattern will inevitably face major amputation. To attain limb salvage in this setting, since the early eighties short vein grafts were used to bypass the occluded infrapopliteal arteries. More recently, percutaneous transluminal angioplasty (PTA) was also attempted to avoid limb loss in selected patients. Since May 1986 in 125 patients 130 autologous bypass grafts from the BK-popliteal artery or the proximal tibioperoneal arteries to malleolar vessels were performed in the presence of extended crural arterial occlusions and critical foot ischaemia (rest pain 3, tissue loss 127). In another series in 89 limbs (rest pain 5, tissue loss 84) of 84 patients PTA was done to treat 168 focal stenoses of > 50% diameter reduction and 11 short occlusions in a total of 135 crural arteries. Using life-table analysis, primary and secondary cumulative patency rates for short vein grafts with distal graft origin were 90% and 98% at 30 days, 76% and 83% at one year and 46% and 49% at seven years, respectively. The corresponding limb salvage rates amounted to 95%, 80% and 63%. Initial complete or partial technical success after PTA of crural arteries could be obtained in 93%: The limb salvage rates achieved were 95% at 30 days, 82% at one year and 63% at six years. Our results suggest that--depending on the extent of lesions--both short vein grafts as well as PTA are successful complementary treatment modalities to avoid limb loss in predominantly diabetic patients with infrapopliteal artery disease and critical ischaemia.

The utility and durability of vein bypass grafts originating from the popliteal artery for limb salvage

Short vein grafts originating from sites distal to the common femoral artery have been reported to be useful in selected patients with tibial artery disease. From 1987 to 1993, we performed 504 consecutive infrainguinal vein bypass grafts, of which 56 (11%) originated from the popliteal artery, 25 above and 31 below the knee. The patients were 16 women and 37 men, with a mean age of 62.4 years. Eighty-seven percent were diabetic, 57% had clinically obvious coronary artery disease, and 28% had end-stage renal disease (ESRD). The indication for surgery was ulceration or gangrene in 93% of cases. We preferentially used reversed greater saphenous vein harvested from the thigh to optimize conduit quality and avoid lower leg wound complications. The outflow artery sites were: dorsal pedal (17), posterior tibial (14), peroneal (10), anterior tibial (8), lateral or medial plantar (5), and sequential tibial (2). All patients were followed postoperatively with serial duplex surveillance. The mean follow-up was 12.5 months (range 1 to 66). In-hospital mortality was 5.4%. Mortality at 24 months was 19% overall and 38% in patients with ESRD. Limb salvage was 77% at 3 years, 92% in patients with normal renal function versus 59% in those with ESRD (P < 0.003). Primary graft patency by life-table analysis was 94% at 1 month and 84% at 3 years. Five patients with patent grafts required amputation, 4 early and 1 late. Eight months after surgery, 1 patient (1.8%) developed superficial femoral artery stenosis which was diagnosed by duplex surveillance and successfully treated by percutaneous transluminal balloon angioplasty. Vein bypass grafts originating from the popliteal artery are effective and durable. Proximal disease progression rarely poses a significant threat to long-term graft patency. Patients with ESRD, blind tibial outflow tracts, and extensive forefoot lesions appear to be at increased risk of limb loss even with continued graft patency.

Short Vein Grafts in Limb-saving Arterial Reconstructions

In the management of limb-threatening infrainguinal arteriosclerosis, the short vein graft is a feature of distal-origin bypass procedures from the superficial femoral and popliteal arteries to more distal arteries. These procedures, which can only be performed in selected patients, have patency rates equivalent to those of comparable bypasses from the common femoral artery. Other advantages include the increased availability of the shorter vein graft segment that is required. Two newer operations that use short vein grafts are tibio-tibial bypasses and bypasses to isolated segments of infrapopliteal arteries. The authors' initial experience with these two procedures includes encouraging patency and limb salvage rates for periods up to 2 years in patients for whom there was no other therapeutic option short of amputation.

Reconstruction for the Vertebral Artery Stenosis at its Origin

Eight patients with vertebral artery (VA) stenosis at its origin were surgically treated by a new reconstructive technique. Two patients suffered vertebrobasilar transient ischemic attacks, and five had brainstem and/or cerebellar infarction. All patients had multiple stenotic lesions, including bilateral VA stenoses in one and unilateral VA stenosis plus contralateral VA occlusion in seven. They underwent a subclavian artery to VA bypass using a saphenous short vein graft with external shunting. Postoperatively, no patients had aggravated neurological symptoms, and angiography showed all bypasses to be patent. One had an episode of transient loss of consciousness 8 months postoperatively, but the others showed no episodes of ischemia during an average follow-up period of 2 years and 10 months. The results indicate that this procedure is safer and more useful than other surgical procedures.

Short vein grafts: A superior option for arterial reconstructions to poor or compromised outflow tracts?

To determine whether vein graft length is a factor that influences infrapopliteal bypass patency, we reviewed 237 consecutive reversed saphenous vein bypasses performed because of critical ischemia during a 5-year period. One hundred seventeen long vein grafts (LVGs) were longer than 40 cm (42 to 92 cm, mean 60.9 ± 9 cm) and 120 short vein grafts (SVGs) were 40 cm or shorter (6 to 40 cm, mean 24.7 ± 8 cm). Ninety-three percent of the LVGs originated from or were proximal to the superficial femoral artery (SFA) whereas all of the SVGs originated at or distal to the SFA. The cumulative patency rate for LVGs at 3 years was 45% and for SVGs was 63% (p < 0.025). In the absence of an intact pedal arch, 3-year patency rates for LVGs (51 cases) and SVGs (78 cases) were 22% and 53%, respectively (p < 0.01). High intraoperative outflow resistance measurements (>0.7 mm Hg/ml/min) were encountered in 25 cases. Of these, occlusion within 6 months occurred in six of seven cases with LVGs and in only 8 of 18 cases with SVGs (p < 0.05). Wound complications at vein harvest sites occurred in 17% of LVGs and in only 6% of SVGs (p < 0.01). Of 16 additional cases in which a proximal patch angioplasty or percutaneous transluminal angioplasty was performed tandem with a short distal vein graft, four occluded (less than 6 months) and 12 remained patent from 3 to 43 months (mean 12.6 months). Thus SVGs, in addition to increasing vein utilization and decreasing wound complications, have superior patency rates, particularly when used in bypasses to disadvantaged outflow tracts. Early results with tandem procedures are encouraging.

Tibiotibial vein bypass grafts: a new operation for limb salvage.

Tibiotibial bypasses were performed with short (8 to 33 cm) segments of reversed autologous vein in 14 patients who did not have longer segments of usable vein. All patients faced imminent amputation unless they had an effective revascularization. Two patients died, one within 1 month of operation. One patient required below-knee amputation despite a patent bypass. Eleven patients (79%) have a patent bypass and a functional limb 6 to 50 months after operation. These good patency results even with several grafts inserted into isolated segments of tibial arteries, some with incomplete plantar arches, suggest that these short vein grafts may be superior to other vein grafts. Tibiotibial bypasses may improve limb salvage results in otherwise difficult circumstances.

Tibiotibial vein bypass grafts: A new operation for limb salvage

Tibiotibial bypasses were performed with short (8 to 33 cm) segments of reversed autologous vein in 14 patients who did not have longer segments of usable vein. All patients faced imminent amputation unless they had an effective revascularization. Two patients died, one within 1 month of operation. One patient required below-knee amputation despite a patent bypass. Eleven patients (79%) have a patent bypass and a functional limb 6 to 50 months after operation. These good patency results even with several grafts inserted into isolated segments of tibial arteries, some with incomplete plantar arches, suggest that these short vein grafts may be superior to other vein grafts. Tibiotibial bypasses may improve limb salvage results in otherwise difficult circumstances.

Short vein grafts for cerebral revascularization.

Experience with the use of a short saphenous vein bypass graft for cerebral revascularization is reviewed. Twenty patients with symptomatic atherosclerotic occlusive disease underwent a total of 21 bypass procedures. Cerebral revascularization was performed using a short (5 to 10 cm) saphenous vein graft (SVG) extending from the superficial temporal artery (STA) trunk anterior to the ear in 19 bypasses, or from the occipital artery (OA) immediately behind the mastoid process to the posterior temporal or angular branch of the middle cerebral artery (MCA) in two bypasses. The early patency rate for the SVG bypasses was 90%. Two of the four patients with SVG occlusion were found to have substantial resolution of a severe inaccessible internal carotid artery stenosis that was present preoperatively. Filling of multiple major branches of the MCA through the SVG was seen in 90% of patients on late postoperative conventional angiography. The STA trunk or proximal OA was consistently found to be enlarged on the late studies. None of the patients had recurrence of cerebral transient ischemic attacks. The procedure may be useful as a primary means of cerebral revascularization or as an alternative approach when a scalp artery cannot be used because of its small size, severity of arteriosclerotic changes (a common occurrence), or damage during its dissection. Cerebral blood flow studies suggest that the use of a short SVG has a more favorable effect upon the cerebral circulation than the conventional bypass procedure.