Event Abstract Back to Event EAT, SLEEP AND REPRODUCE... EVOLUTION OF REPRODUCTIVE HORMONES AND RECEPTORS IN THE KOALA: NEW SEQUENCES AND PHYLOGENY Ellen R. Busby1, Nancy M. Sherwood1* and Stephen D. Johnston2 1 University of Victoria, Department of Biology, Canada 2 The University of Queensland, Australia Studies of the hypothalamic-pituitary-gonadal axis in marsupials are limited to in vivo studies of the brushtail possum and in silico studies of the sequenced genome for the grey short-tailed opossum, so that knowledge of the mechanisms that regulate reproduction in this taxon is incomplete. To further appreciate the unique reproductive biology of marsupials (koala), there is a need to develop tools that allow the measurement and alteration of the hypothalamic and adenohypophysial hormones and receptors. This report presents sequence data for the gonadotropin-releasing hormone (GnRH) peptides their respective receptors, follicle stimulating hormone (FSH) and luteinizing hormone (LH) in the koala (Phascolarctos cinereus). Phylogenetic analysis of these reproductive hormones and their receptors, along with those from other vertebrates, allows identification of homologs in the vertebrate lineage and clarifies the evolutionary relationship for these three subclasses of mammals. [supported by a Canadian NSERC grant to NMS and an Australian Dreamworld Research Grant to SDJ]. Keywords: evolution, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Luteinizing Hormone, marsupial, phylogeny Conference: NASCE 2011: The inaugural meeting of the North American Society for Comparative Endocrinology, Ann Arbor, United States, 13 Jul - 16 Jul, 2011. Presentation Type: Poster Topic: Molecular evolution Citation: Busby ER, Sherwood NM and Johnston SD (2011). EAT, SLEEP AND REPRODUCE... EVOLUTION OF REPRODUCTIVE HORMONES AND RECEPTORS IN THE KOALA: NEW SEQUENCES AND PHYLOGENY. Front. Endocrinol. Conference Abstract: NASCE 2011: The inaugural meeting of the North American Society for Comparative Endocrinology. doi: 10.3389/conf.fendo.2011.04.00113 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 22 Jul 2011; Published Online: 09 Aug 2011. * Correspondence: Prof. Nancy M Sherwood, University of Victoria, Department of Biology, Victoria, BC, V8W 3N5, Canada, nsherwoo@uvic.ca Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Ellen R Busby Nancy M Sherwood Stephen D Johnston Google Ellen R Busby Nancy M Sherwood Stephen D Johnston Google Scholar Ellen R Busby Nancy M Sherwood Stephen D Johnston PubMed Ellen R Busby Nancy M Sherwood Stephen D Johnston Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.