Short End Research Articles

Rethinking a fundamentalist literalist reading of Mark 16:18 by some new prophetic churches

Some of the New Prophetic Churches apply the fundamentalist literalist reading of the biblical text in their sermons and theology because of a lack of knowledge and application of proper reading and interpretation of scripture. The fundamentalist literalist reading of scripture particularly Mark 16:18 is linked here to the abuses by some of the pastors in New Prophetic Churches. In addressing these challenges, this article proposes a proper exegetical study of Mark 16:18 that pays attention to the context of the text, the historical background and the grammar of the text. This will be achieved by giving a background to a fundamentalist literalist reading of scripture in Pentecostalism particularly as practised by New Prophetic Churches in South Africa. The article will also highlight some of the challenges posed by the fundamentalist literalist reading of scripture. The final section is an exegetical study of Mark 16:18, which is interpreted by recognising the whole passage of Mark 16:9–20 even though some New Testament scholars do not recognise this longer ending. This article reflected on this passage in response to the fundamentalist literalist reading among New Prophetic Churches not necessarily to enter the debate between the short ending and longer ending.Contribution: This article challenges fundamentalist literalist reading of scripture in New Prophetic Churches. The article proposes a thorough exegetical reading of Mark 16:18 that recognises the exegetical tools such as history, grammar and the context of the text.

The impact of macroeconomic news sentiment on interest rates

We provide evidence that sentiment extracted from articles related to interest rates, inflation, and the labor market has the ability to explain short-term interest rate movements that cannot be accounted for by professionals’ and consumers’ expectations. Additionally, sentiment can pin down two short rate regimes that are correlated with the business cycle. By combining these results with a yield curve model, we find that market sentiment has a statistically significant negative effect on the short end of the yield curve and a positive effect on the slope. We also show that sentiment improves the out-of-sample forecast accuracy of short-term yields.

More than Just a Number: Perspectives from Black Male Participants on Community-Based Interventions and Clinical Trials to Address Cardiovascular Health Disparities.

Black Americans remain significantly underrepresented and understudied in research. Community-based interventions have been increasingly recognized as an effective model for reckoning with clinical trial participation challenges amongst underrepresented groups, yet a paucity of studies implement this approach. The present study sought to gain insight into Black male participants' perception of clinical trials before and after participating in a community-based team lifestyle intervention in the United States. Black Impact, a 24-week community-based lifestyle intervention, applied the American Heart Association's Life's Simple 7 (LS7) framework to assess changes in the cardiovascular health of seventy-four Black male participants partaking in weekly team-based physical activities and LS7-themed education and having their social needs addressed. A subset of twenty participants completed an exit survey via one of three semi-structured focus groups aimed at understanding the feasibility of interventions, including their perceptions of participating in clinical trials. Data were transcribed verbatim and analyzed using a content analysis, which involved systematically identifying, coding, categorizing, and interpreting the primary patterns of the data. The participants reported a positive change in their perceptions of clinical trials based on their experience with a community-based lifestyle intervention. Three prominent themes regarding their perceptions of clinical trials prior to the intervention were as follows: (1) History of medical abuse; (2) Lack of diversity amongst research teams and participants; and (3) A positive experience with racially concordant research teams. Three themes noted to influence changes in their perception of clinical trials based on their participation in Black Impact were as follows: (1) Building trust with the research team; (2) Increasing awareness about clinical trials; and (3) Motivating participation through community engagement efforts. Improved perceptions of participating in clinical trials were achieved after participation in a community-based intervention. This intervention may provide a framework by which to facilitate clinical trial participation among Black men, which must be made a priority so that Black men are "more than just a number" and no longer "receiving the short end of the stick".

Abstract LB108: Specific plasma DNA end-motifs distinguish patients with lung adenocarcinoma versus benign nodules

Abstract Background: Recent studies have identified blood plasma DNA as a rich source of biomarkers for non-invasive cancer detection. In particular, analysis of shorter DNA fragments or “fragmentomics” have shown promising results with numerous competing approaches such as those based on mutation calls, length distributions, or preferred fragmentation patterns. In this study, we assessed the potential of fragment end motif distributions in discriminating patients with lung adenocarcinoma versus benign tumors. Methods: Plasma samples from 37 patients (20 benign, 17 malignant) were subject to whole genome sequencing. For each sample, DNA fragments were grouped as short (30-99bp) and long (100-269bp) and end motif distributions were calculated by counting occurrences of 4-9bp sequences at either the 5’ or 3’ end of each fragment. A proprietary machine learning algorithm was employed to identify a minimal set of motifs capable of accurately distinguishing benign from malignant samples. Results: Just two 5’ end motifs in long fragments, CCAT and GACA, were sufficient for distinguishing malignant from benign samples in a two-step decision tree (89% accuracy with all samples, 86% accuracy in leave-one-out cross validation). Accuracy was significantly higher when compared to random guessing by shuffling labels (p=1.6*10−6, FWER < 0.05, Bonferroni correction, 351 tests). CCAT motif frequency was also significantly associated with cancer stage (p=0.04, Kruskal-Wallis test) and specifically elevated in early stage samples (I, II). Conclusions: These results suggest that plasma DNA end motif distributions are informative in discriminating patients with lung adenocarcinoma versus benign tumors. The two-motif model suggests that specific, rather than systemic changes in end motif distributions are more strongly associated with lung cancer patients and may point to specific mechanisms linked to cancer progression. Citation Format: Jason C. Hyun, Shun H. Yip, Neeti Swarup, Raghuraman Ramamurthy, Jordan C. Cheng, Irene Choi, Edmund Wong, Akanksha Arora, Denise Aberle, David T. Wong, Cheuk Y. Tang. Specific plasma DNA end-motifs distinguish patients with lung adenocarcinoma versus benign nodules [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 2 (Late-Breaking, Clinical Trial, and Invited Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(7_Suppl):Abstract nr LB108.

Different Retinopathy of Prematurity Severity, Onset Therapy and Outcomes in Triplet Babies: A Case Report

Introduction : Retinopathy of prematurity (ROP) is a vasoproliferative disease of the premature infants, characterized by abnormal vascularization at the junction of vascular and avascular retina. Intravitreal anti-VEGF injection is one of promising management of ROP. The aim is to present the therapy outcomes of triplet babies with different severity and onset therapy.
 Case Illustration : This case shows ROP in triplets born at 25-26 weeks gestational age. First baby, weighed 630 g with Bilateral Stage 2 Zone II Posterior with Plus Disease treated with intravitreal ranibizumab injection at 11 weeks (PMA 36-37 weeks). Second baby, weighed 620 g and get bilateral intravitreal ranibizumab injection a week after first baby, left eye got worse on first week, but getting better on the last follow up. Third Baby, weighed 750 g with bilateral Stage 3 Zone I with Plus Disease (worst eye condition), but because he had worst general condition, so the latest got screening, got no intervention. Two babies were treated with anti-VEGF therapy – bevacizumab. All babies has outcome regression, no recurrence of ROP in those short term end point, and no adverse reactions were observed until the last follow up at 27 weeks old (PMA 52-53 weeks) recorded for all babies.
 Discussion : 
 Conclusion : Primary prevention through well-managed screening programme for premature infants was the more effective way to manage the ROP. Intravitreal anti-VEGF treatment could be promising for management of ROP if it was given on the right time and early stadium.

Development and testing of a three-period, subsize 2G AIMI MgB2 planar undulator

Compared to Nb3Sn- and NbTi-wound superconducting undulators (SCUs), MgB2-wound SCUs are of interest for future electron synchrotron beam light sources owing to their higher temperature operating margin and associated stability. In this study, a three-period undulator consisting of twelve racetrack coils wound with 2nd generation (2 G) multifilamentary advanced-internal-magnesium-infiltration MgB2 strands were fabricated and tested in liquid and gaseous helium (He) over a temperature range of 4.2 K–20 K. The coil winding cross sections (in each coil) were 5 mm wide and 4.8 mm thick. At 4.2 K, a critical current (I c) of 325.7 Amps produced a maximum undulator bore field of 1.19 T. It should be noted that the short, 3-period nature of the coil led to an asymmetry in the field profile (the maximum positive field was 1.19 T, the maximum negative was −0.25 T), suggesting a peak field of 0.72 T in the absence of end effects. Finite element modeling (FEM) results of simulations for a one meter long undulator of otherwise identical design gave 0.85 T (larger because of higher currents enabled by the lower field). But in any case, the I c value coil reached is 94% of that of the short sample (dictated by the 1.19 T positive field for the coil as tested). FEM was performed to study the magnetic field profile, which was validated experimentally. The magnetic field was measured using a Hall probe which was translated along the beam axis during measurement to explore the spatial field variation along the beam travel direction. The spatially alternating field was asymmetric, and the maximum field was more prominent in the positive direction than in the negative direction, the difference being due to broken symmetry, that is, short coil end effects. In this work, we show useful fields are possible for MgB2 undulators; the use of such conductors can allow a larger thermal margin and enable conduction-cooled operation.

Male-Specific Sequence in Populus simonii Provides Insights into Gender Determination of Poplar

The genus Populus is composed of dioecious woody plants and adult females produce large numbers of seed hairs that can affect public health and pose a potential fire risk. However, it is difficult to distinguish between males and females based on their morphology at the seedling stage. Therefore, developing a technology that identifies the gender of poplar seedlings is crucial for controlling seed hairs. In this study, we developed an approach for the early gender identification of Tacamahaca and Aigeiros species based on the male-specific sequence in Populus simonii. The gender of Tacamahaca and Aigeiros species can be accurately identified by PCR. The sequencing results showed that the male-specific sequence was conserved in P. simonii and its F1 progenies. Interestingly, there were three nucleobase differences between Tacamahaca and Aigeiros species. Sequence alignment showed that the male-specific sequence had not been assembled on the pseudochromosome. Subsequently, fluorescence in situ hybridization (FISH) was used to locate this specific sequence at the short arm end of chromosome 19 in male P. simonii. This study provides an efficient and convenient method for early gender determination of Tacamahaca and Aigeiros species and lays the groundwork for exploring key sex-determination genes.

A Comparative Study of Conventional Transition Model and Reverse Transition Model for Wireless and Radar Applications

Microstrip line-to-waveguide transitions (MLWT) finds various applications in the field of RADAR engineering, navigation science, medical electronics, household equipment, satellite tracking equipment, wireless communications etc. Conventionally, the MLWT is designed so that the microstrip line is inserted in E-plane and perpendicular to the waveguide’s side wall, while the microstrip probe’s radiating face is towards the waveguide’s open end port. In this paper, an MLWT has been designed for Ka-band applications and the transition has been designed in such a way that the radiating face of the inserted microstrip line probe is towards the short circuit end of the waveguide. The method is called the reverse transition method. The microstrip signal reflected from the short circuit end comes in additive phase with the traveling wave and the strength of the traveling wave increases. MLWT has been developed using this method and results for Ka-band applications are presented in this paper. This work reported more than 20 dB improvement in return loss (RL), 0.1dB improvement in insertion loss (IL) and almost 7 to 8% enhancement in 10dB fractional bandwidth compared to the conventional method. Comparative analysis of the two methods has been shown in tabular form at the end of the paper.

Comparative Study of Various Slot Pitches for 2-Pole 6-Slot Ultra-high-Speed Permanent Magnet Synchronous Motors

The 2-pole 6-slot permanent magnet synchronous motor (PMSM) is an attractive option for ultra-high-speed (UHS) applications due to its excellent manufacturability and balanced magnetic force. UHS PMSMs should be designed with short stack lengths and end coil heights to address rotor dynamics issues. Additionally, given their high frequency, these PMSMs should be designed considering stator iron loss, rotor eddy current loss, and AC copper loss. The performance of the same pole-slot combination varies significantly based on the slot pitch. Hence, we compared the size and efficiency of the 2-pole 6-slot UHS PMSM based on the slot pitch. For a fair comparison, an optimal design was performed for each slot pitch. To reduce computation time, optimization was conducted in two stages: size minimization and efficiency maximization. It was confirmed that in terms of total axial length, the 1-slot pitch UHS PMSM is the shortest due to the advantage of having a short end coil height, even with the lowest winding factor and largest stack length. Furthermore, it was determined that the 2-slot pitch UHS PMSM offers an excellent trade-off between efficiency and size.

FRI445 A Late Diagnosis Of Complete Androgen Insensitivity Syndrome

Abstract Disclosure: J. Muuse: None. R.J. Shah: None. P.A. Belany: None. Introduction: Complete Androgen Insensitivity Syndrome (CAIS) is a rare disorder of hormone resistance characterized by a female phenotype in an individual with an XY karyotype. Individuals with CAIS are born unambiguously female without any apparent abnormalities. They develop a short blind ending vaginal canal, with absence of Wolffian duct derived structures (vas deferens, seminal vesicles). Breast development advances regularly at puberty, while there is absent pubic and axillary hair, both due to peripheral conversion of testosterone to estrogen. Testes remain undescended in the abdominal cavity. Case: A 28 year old female with a past medical history of bipolar disorder presented to her primary care physician’s office with a chief complaint of fatigue. Blood work revealed an elevated testosterone level of 686, at which time she was referred to endocrinology for further work up. On further history gathering, she endorsed a life long history of amenorrhea. She saw an OB-GYN at 19 years old and was told she had a short vaginal canal. A pelvic ultrasound revealed no uterus and one left ovary. She was not given a diagnosis other than congenital absence of a uterus. She was lost to follow up until 28 years of age when she sought medical help for her fatigue. Physical exam was pertinent for a tall female with no signs of hirsuitism. Additional blood work revealed normal LH, FSH, and DHEA-S. A chromosomal analysis revealed XY. She was referred to gynecology for further management and assessment for orchiectomy. Discussion: This was an unusual case of CAIS, as this was diagnosed far past menarche. Most cases are diagnosed during puberty- which aids in an early approach towards the psychological and social well being of the individual as well as close follow up for evaluation of orchiectomy. Orchiectomy is recommended due to the increased risk of gonadal malignancy following puberty. The risk of developing malignancy increases with age, and has been reported to be between 15-22%. Thus it is important to identify this syndrome early in life to ensure this is addressed. It is followed by long term hormonal therapy with estrogen to maintain normal breast and bone development. This case highlights the importance of maintaining a high clinical suspicion of CAIS in females presenting with short vaginal canal and absence of a uterus in order to prevent malignancy and provide optimal psychological support to the individual. Presentation: Friday, June 16, 2023

Direct drive double fed wind generator

An electric machine topology characterized by single tooth winding in both stator and rotor is presented. The proposed machine is capable of operating as a direct drive double fed wind generator (DDDF, D3F), because it requires no gearbox. A wind turbine drive built around a D3F generator is cheaper to manufacture, requires less maintenance and has a higher energy yield than its conventional counterparts. The all tooth wound generator of a D3F turbine has a superb volume utilisation and lower stator I2R losses due to its extremely short end windings, efficient cooling and reduced active length. Both stator and rotor of a D3F generator can be manufactured in segments, which simplifies its assembly and transportation to the site, and makes its production cheaper.

Removal of pharmaceuticals and personal care products from wastewater via anodic oxidation and electro-Fenton processes: current status and needs regarding their application.

This review provides a current opinion on the most recent works that have been published toward the application of electrochemical advance oxidation processes (EAOPs) for the degradation of pharmaceutical and personal care products (PPCPs) in water streams. Advances in the application of anodic oxidation (AO)- and electro-Fenton (EF)-based processes are reported, including operational conditions, electrode performance, and removal. Although AO- and EF-based processes can easily reach 100% removal of PPCPs, mineralization is desirable to avoid the generation of potential toxic byproducts. The following section exploring some techno-economic aspects of the application of EAOPs is based on electrode selection, operational costs as well as their use as cotreatments, and their synergistic effects. Finally, this short review ends with perspectives about the emerging topics that are faced by these technologies applied for the degradation of PPCPs in research and practice.

Analysis of Heart Rate Variability during the Performance of the Wim Hof Method in Healthy Subjects.

Cardiorespiratory interaction is related to the heart rate variability (HRV) synchronized with respiration. These metrics help to comprehend the autonomic nervous system (ANS) functionality in cardiovascular mechanisms. In this work, we aim to study the HRV in healthy subjects aged 18-24 years during the breathing techniques based on deep breaths followed by apnoeas, developed by Wim Hof (WHM). The attributes of all participates have been treated as a group and therefore, separated by gender. A total of 11 intervals have been distinguished: starting of basal respiration (SRI = 1), controlled deep breaths (CDB = 3), long expiratory apnoea (LEA = 3), short inspiratory apnoea (SIA = 3) and ending with basal respiration again (FRI = 1). To strengthen the HRV knowledge extraction from these scenarios, time and frequency analysis is conducted. In general, breathing and apnoea intervals presented significant statistically differences (p < 0.05), heart rate (HR) mean between SRI and FRI (p < 0.001), RR variability of LEA intervals (p < 0.01), root mean square of RR intervals during CDB (p < 0.05), maximum high frequency (HF) peak amplitude between SRI and FRI (p = 0.016), and low frequency (LF) area for LEA intervals (p < 0.001). When performing the frequency analysis, it has been observed that the sympathetic nervous system (SNS) has a higher contribution in the apnoea intervals. In conclusion, the WHM method implementation seems to involve a decrease in the HR. Specific breathing techniques could help to control the body in different conditions.Clinical Relevance- The WHM seems to imply a decrease on HR. Furthermore, after the implementation of the WHM, women presented higher HRV.

The vascular cambium revisited

Summary The vascular cambium presents fundamental questions about the evolution and developmental biology of plants. Over time, our perspectives of the vascular cambium have changed as new molecular and genetic approaches have augmented anatomical observations and are now providing new insights into longstanding topics related to vascular cambium evolution, development and function. At the same time, practical applications of knowledge of the vascular cambium associated with climate change give new urgency to research of how the cambium produces varied wood anatomies both among species and within individual trees that influence response to drought and heat stress. Here, two topics are discussed that are generally related to the storied research of Sherwin Carlquist and his pursuits of the vascular cambium; the identity and function of cambium initials, and the plasticity of wood anatomical traits related to adaptive hydraulic traits. This short paper ends with a call for integrative research that could provide new insights into how trees respond to climate change that take advantage of the comparative wood anatomy framework so well-articulated by Carlquist.

Effects of a nurse-led structured home visiting program on quality of life and adherence to treatment in hemodialysis patients.

This study aimed to determine the effects of a nurse-led structured home visit program on quality of life and adherence to treatment in patients undergoing hemodialysis. The study was quasi-experimental research in which 62 hemodialysis patients referred to Bu Ali hospital in Ardabil participated in two groups: Intervention (n = 31) and control (n = 31). The intervention included a structured and planned home visit program that was performed in five stages over 3 months. Data collection tools were a demographic information form, Kidney Disease Quality of Life Short Form (KDQOL-SF™) and End Stage Renal Disease Adherence Questionnaire (ESRD_AQ) which were completed by patients before, at the end of the first, second, and third month of intervention. SPSS v20 software and descriptive and analytical tests (Chi-square, t-test, ANOVA and repeated measure) were used for data analysis. Examining demographic characteristics showed that there is a negative and significant relationship between age and quality of life scores (P = 0.004), that is, with increasing age, the quality of life score decreases, but other demographic characteristics did not have a significant relationship with quality of life scores and adherence to treatment (P > 0.05).Also, the results showed that in the intervention and control groups, during the study, the scores of quality of life and adherence to treatment increased significantly, and this increase was significantly higher in the intervention group than in the control group (P < 0.001).The scores of quality of life and adherence to treatment increased significantly both during the study in each group separately and between groups during the study (P < 0.001). According to the significant improvement in quality of life and adherence to treatment in patients following a home-visiting program during 3 months, these interventions can be utilized to improve quality of life and adherence to treatment of patients undergoing hemodialysis. Home visiting programs significantly improve the level of knowledge of patients undergoing hemodialysis and their family members, through their involvement in the care process. Having said that, it seems plausible to implement home visits in the standard care plans of hemodialysis patients.

Study of terrestrial diatoms in corticolous assemblages from deciduous trees in Central Europe with descriptions of two new Luticola D.G.Mann taxa.

Although many studies have examined the algae associated with various habitats in tree trunks, the diatoms in these environments are still poorly studied. Studies of corticolous algae mainly focus on green algae and cyanobacteria, which are usually immediately visible, while diatoms are mostly overlooked or not reported. During the research, 143 species of diatoms were identified, including two new representatives of the genus Luticola: L.bryophilasp. nov. with relatively large central area and short distal raphe endings and L.confusasp. nov. characterized by the presence of small depressions on central raphe endings. Both are described herein based on light and scanning electron microscopy observations and compared to similar taxa based on literature data. Basic morphological data for almost all the diatom taxa are noted, and their habitat requirements, and photographic documentation are also presented. The present research showed that the occurrence of diatom assemblages on tree trunks is influenced by various factors like host tree species, the area where the host tree grows, and the availability of suitable microhabitats within the trunk. However, the species composition of this assemblages depends mainly on the tree species.

Research on accurate thermal network calculation model of modular permanent magnet motor

This paper proposes a thermal network model for calculating the modular permanent magnet motor’s temperature rise. Analyzing the actual heat flow path of motor Joule loss and considering the circumferential heat conduction of winding, the local three-dimensional thermal network model of winding is constructed. Based on the model, the motor parts’ steady and dynamic temperature rise is calculated and verified by the FEM. The thermal network model also applies to motors with short winding ends and complex stator yokes.

“Into the Widest Imagination”

“Into the Widest Imagination”

Synthesis of a polarisation‐rotating surface with reflective filtering response based on orthogonally inserted coupled slot‐lines

AbstractIn this article, a three‐dimensional polarisation‐rotation surface (PRS) with reflective filtering response based on two orthogonally inserted coupled slot‐line is investigated, which can reflect a vertically/horizontally polarised incident wave by 90°. Each unit cell of the PRS is composed of a pair of meandered slot‐line sections with open‐short‐ends etched on the vertically and horizontally inserted single‐layer printed circuit boards. Under the incidence of a linearly polarised plane wave along the vertical/horizontal direction, the plane wave is converted into the guided wave by the open‐circuited end of the slot‐line section, and then the guided wave is obstructed by the short end of the slot‐line section and coupled to the other slot‐line section, thus leading to 90° polarisation rotation. To simplify the design procedure, a matrix coupling theory is applied to synthesise and design the proposed PRS. A sample with fractional bandwidth of 20% at the centre frequency of 5 GHz and return loss of 20 dB is designed, fabricated, and measured for verification. The measured and simulated results are in good agreement with the theoretical ones. The results confirm that the proposed PRS has low insertion loss, high polarisation conversion ratio, and stable filtering performance for oblique incident angle up to 60°.

Tuning Dimensionality of Benzimidazole Aggregates by Using Tetraoctylammonium Bromide: Enhanced Electrochemiluminescence Studies

Exploring the depolymerization strategy of liposoluble luminophores in the aqueous phase is vital for the development of electrochemiluminescence (ECL). In this work, tetraoctylammonium bromide (TOAB) with four long hydrophobic chains and short hydrophilic ends is used as a template to limit the aggregation of benzimidazole (BIM). By adjusting the loading of BIM on the hydrophobic chains of TOAB, a two-dimensional lamellar BIM/TOAB is formed, the ECL intensity of which is 6.4 times higher than that of the aggregated BIM (H2O2 as the coreactant). In terms of ECL spectroscopies, cyclic voltammetry , ECL transients, and the adjustment of the scanning potential range, the ECL mechanism is thoroughly studied. This work provides a new way to depolymerize organic luminophores and reveals a possible pathway in the annihilation ECL mechanism.