Background and AimsThere are differents factors that will influence the functional capacity of ACKD patients, among them the nutritional condition.Aimto assess the functional capacity of ACKD patients with the Short Physical Performance test Battery (SPPB), and its relationship with the malnutrition-inflammation binomium.MethodWe have evaluated 216 ACKD patients, 66.2% (143) male. xage 70.85 ?12.01 years, being female older than male (72.58 ?13.19 vs 69.96 ?11.32, p = 0.129). We have determine plasma proteins indicators of nutritional status such as albumin, prealbumin and CRP as a marker of the status of inflammation. And we have applied malnutrition inflamation score (MIS).ResultsIn the univariate analysis, we found an association between the functionality determined with the test and the age (RR95% 0.866 p = 0.000), sex (RR95% 0.387 p = 0.005). albumin (RR95% 2,222 p = 0.035), prealbumin (RR95% 1.065 p = 0.018), CRP (RR95% 0.733 p = 0.022) and the state nutritional value determined with the MIS scale (RR95% 0.791 p = 0.000). We donot any found any association with DM, transferrin and total lymphocytes. Albumin values were established as 3.8g / dl, and CRP at 1g / dl, obtaining 4 groups: (G1: alb> 3,7-PCR <1, G2: alb> 3,7-PCR> 1, G3: alb <3,7-PCR <1 and G4: alb <3,7-PCR> 1 ).The table shows the results of the relationship between groups and the limitations determined with SPBB. Group 1 was the most numerous, also being the one with the best nutrition-inflammation profile, observing that in this group 68 patients (78.2%) presented minimal / no limitations.Conclusions1. The nutritional-inflammation status will influence the functional capacity of the patient with ERCA.2. The SPPB test, in addition to being a good choice to evaluate the functional capacity of patients with ACKD, can provide guidance on the nutritional status of patients.3. Maintaining a good nutritional status will also have a positive influence on the functional capacity of ACKD patients.MO606 Table 1:Transplant Kidney Biopsy Findings from Positive COVID-19 CasesG1:G2:G3:G4:*pAlb>3.8 * CRP<1Alb>3.8 * CRP>1Alb<3.8 * CRP<1Alb<3.8 * CRP>1Severe limitations66.7% (8)0,0% (0)25% (3)8.3% (1)0.012Moderates Limitations64.9% (24)27% (10)0,0% (0)8.1% (3)Mild Limitations83.3% (65)7.7% (6)6.4% (5)2.6% (2)M?mal Limitations78.2% (68)10.3% (9)5.7% (5)5.7% (5)*P<0.05 (sig.) (Fisher test)