The scheduling problem is a common challenge when it comes to executing tasks, making the resolution of this issue crucial for decision-making in production activities. The problem addressed in this research is the company's desire to conduct production without waiting times between stages to maintain the quality of pharmaceutical raw materials. Additionally, the production results must meet predefined due dates. The production system formed is a Hybrid Flow Shop system, which is an extension of the Flow Shop concept where one or all stages have identical parallel machines. The objective of this study is to minimize the time between job start and job completion, defined in scheduling problems as the minimization of mean Flow time. The research collected data from 5 products in the company to model according to the research objectives. Process times for each stage and due dates for each product have been predetermined. After modeling and processing using the LINGO application, the optimal result obtained is backward scheduling with an average flow time of 12.6. This demonstrates that the model in this research effectively addresses the Hybrid Flow Shop problem using backward scheduling to minimize mean flow time