The subway’s daily management and control are too complicated to be handled by using traditional methods. Based on the artificial systems, computational experiments, and parallel execution (ACP) approach, the Parallel Transportation Management and Control System for Subways (PTMS -Subway) is proposed. First, the dynamic status perception and management platform for subways (SPMP-Subway) is constructed, and artificial subway systems (ASS) are designed and constructed, and then they are validated by the real-time data from SPMP-Subway. Then, the design content and construction process of computational experiments platform are performed. Finally, through the interactions of parallel execution system between actual subway and its ASS, a set of practical management and control algorithms can be validated and improved. PTMS-Subway can implement those advanced functions, such as real-time monitoring, warning, forecasting, scheduling optimization, incidence management, and so on, to improve its reliability, efficiency, safety, and service level. SPMP-Subway and PTMS-Subway have been piloted in Subway Lines 1 and 2 in Suzhou, China, and achieved the expected results and benefits successfully.