Shift Of Absorption Peak Research Articles

Simultaneous Optimization Approach for UV-C Radiator to Enhance Mechanical Properties of Semi-Finished Potato Tuber (Innovator) for Extended Storage Period

The efficacy of surface treatment technology is highly dependent on the dimensional and operational parameters. UV-C as a commonly used surface treatment technology required fine-tuning to achieve maximum storability of semi-finished products. This study therefore applied a simultaneous optimization approach for the multi-objective function to obtain the best possible combination of variables in the irradiation process (dose (15-45mJ/cm2, storage period (3-9d), and distance from the light (40-80cm)) that offer maintained properties of semi-finished potato tuber for extended storage life. The optimum values are obtained at the ~40.5mJ/cm2, 7 days, and 48cm granting a 756N, 6.7N, and 9N for compressive, bending, and cutting force resistance, respectively. Further insight into the surface functionality was studied using FT-IR and SEM analysis as a result similar spectral makeup was noted but a shift of absorption peak was observed in the irradiated sample at 30 and 45mJ/cm2. Also, a similar granular structure was observed from the morphologies.

Dynamic Wavelength-Selective Diffraction and Absorption with Direct-Patterned Hydrogel Metagrating.

Hydrogel nanophotonic devices exhibit attractive tunable capabilities in structural coloration and optical display. However, current hydrogel-based tunable strategies are mostly based on a single physical mechanism, and it remains a challenge to merge multiple mechanisms for active devices with integrated functionalities. Here, a hydrogel metagrating combining Fabry-Pérot (FP) resonance and diffraction effects is proposed for achieving tunable absorption and dynamic wavelength-selective beam steering. Through exploiting hydrogel shrinkage under electron-beam exposure, a hydrogel nanocavity composed of Ag/Hydrogel/Ag three-layer films can be directly printed with arbitrary patterns, enabling the direct-pattering technique of metagrating. The hydrogel nanocavity performs as an FP-type absorber, and its absorption peak rapidly shifts with humidity variation due to the hydrogel layer scaling. The response speed is <320ms, and the absorption peak shift range is >150nm. It is further demonstrated that the hydrogel metagrating exclusively deflects light at the resonance wavelength, and its operating wavelength can be actively switched by regulating ambient humidity. The proposed tunable hydrogel metagrating can promote new technologies of tunable metasurfaces for optical filtering, gas sensing, and optical imaging.

The influence of carbon content to the band gap of ABC stacked trilayer hybridized graphene and hexagonal boron nitride

The influence of carbon content on the band gap of ABC stacked trilayer hybridized graphene and hexagonal boron nitride (h-BNC) are calculated by first-principles calculations. The formation energy results indicate that the configurations with cluster of boron(B) and nitrogen(N) atoms are more stable than that with separate. By calculating the band structures of seven doping models, we found that the band gap reduces with the ascendance of carbon atom concentration. With the increase of the carbon atom content, the optical absorption peak shifts to longer wavelength range. Combined with the band structure results, the red-shift is due to the reduction of the bandgap with the increase of the carbon atom content. The density of states, charge densities and Mulliken populations suggest that the collapse of the band gap is attributed to the charge transfer between atoms in the seven doping models of the h-BNC system. This work is valuable for the band structure engineering of h-BNC.

The Dynamic Impact of Synthetic Dyes on the Physicochemical Parameters of Cationic and Anionic Surfactants

Introduction: The interaction of dyes (crystal violet, malachite green, and congo red) with cationic (cetrimide) and anionic surfactants (sodium dodecyl sulfate) in the aqueous medium were studied via conductometric and UV-visible spectroscopy. Method: The critical micelle concentration (CMC) of both cetrimide and SDS upsurges in all the selected dyes on increasing the temperature. Thermodynamic parameters like change in Gibb’s free energy of micellization (Δ G°m ), change in enthalpy of micellization (Δ H°m ) as well as change in entropy of micellization (Δ S°m ) were calculated by employing mass action model. Result: The Δ S°m values obtained are positive with Δ G°m and Δ H°m values being negative signified that the phenomenon of micellization is spontaneous as well as exothermic in nature. Moreover, the more negative Δ H°m in water as well as in the presence of dyes signify the presence of electrostatic forces of attraction between the oppositively charged dyes and surfactant moieties. UV-spectroscopy reveals that spectral changes occur because of the interaction of surfactants with dye molecules. Conclusion: By analyzing shifts in absorption peaks, changes in intensity, and alterations in band shape, insights into the nature of surfactant-dye complexes and their potential applications in various industries can be assessed. This understanding can help in the design and optimization of products and processes involving surfactants and dyes.

A miniaturized dual band terahertz metamaterial based absorber as a biosensor for non-melanoma skin cancer diognostic

Early diagnosis of Non-melanoma skin cancers (NMSCs) is most important for successful treatment of the disease.The detection of NMSCs involves visual inspection or invasive method of detection by skin biopsy. Recently, terahertz spectroscopy has come into limelight for detection of biomarkers in low terahertz (THz) region in between 0.1 – 10 THz which will be in resonance with the biomolecules. This work entails in designing a microscale THz metamaterial absorber for discriminating the attributes between Non-melanoma skin cancerous skin and normal skin. The proposed absorber is composed of space filling curved aluminum layer over a polymide substrate. The absorber culminates its absorbance peak of 99.8 % at 0.503 THz and 99.5 % at 1.076 THz, revealing its dual band trait. Moreover, variation of refractive index of the medium from 1.3 to 1.4 shows shift in absorption peak with a sensitivity of 95.76 GHz/RIU and 100 GHz/RIU for first and second band respectively.

Metasurface Absorber for Blood Hemoglobin Concentration.

In this study, a biosensing scenario is developed for monitoring blood quality based on the detection of blood hemoglobin concentration. The procedure involves considering the blood sample as the dielectric with different refractive indexes for different concentrations of hemoglobin. Usually, the sensitivity to design parameters is the major issue with the metasurface-based detection. To address this issue, a three-layer graphene-based wave absorber is designed and modeled using passive circuit elements. The major idea behind this work is to maximize the device sensitivity against the blood sample. The research methodology involves impedance matching between the device and the surrounding environment, while full-wave simulation is also performed and compared to ensure circuit view accuracy. The findings suggest that the proposed graphene-based absorber can efficiently monitor blood quality via dual absorption peaks. The simulation results extracted from impedance matching and the full-wave method indicate frequency shifts of the second absorption peak. These shift values are interpreted based on hemoglobin concentration. Additionally, ample analyses are provided to show the reliability of the proposed absorber against geometrical aspects, incident angle, external stimulation, and the graphene electron relaxation time.

Physiological response of Bidens pilosa to cadmium stress monitored by Fourier Transform Infrared Spectroscopy

The cadmium (Cd) pollution of soil causes serious environmental problems. The present paper deals with the physiological response of the changes in chemical components in the root, stem and leaf of Bidens pilosa seedlings stressed by excess cadmium ions (Cd2+) using Fourier transform infrared spectroscopy technique (FTIR). Cadmium accumulation in plant and distribution in subcellular by atomic absorption spectroscopy were tested under different concentrations cadmium stress. Results indicated that at a Cd concentration of 7 mg·L-1, B. pilosa maintained normal growth without visible Cd toxicity symptoms, though biomass was reduced compared to controls. FTIR analysis revealed that the overall peak shapes of roots, stems, and leaves remained largely unchanged before and after heavy metal treatment, suggesting that the structural integrity of plant organs was not compromised. However, shifts in specific functional group absorption peaks, including hydroxy (3387-3417 cm-1), carboxyl (1411-1419 cm-1), and amide groups (1635 cm-1), were observed, indicating their involvement in the heavy metal absorption process. The characteristic peak intensity of leaves was higher at high Cd concentration than at medium-low Cd concentration, while peaks in stems and roots remained consistent with or exceeded those of the control group. Cd predominantly accumulated in cell walls (46.21%-55.32%) and was minimally distributed in chloroplasts and mitochondria (4.11%-8.43%). These findings suggest that B. pilosa exhibits strong tolerance to Cd-contaminated soil and has significant potential for phytoremediation. The FTIR method offers strong evidence supporting the development of phytoremediation technology.

Integrated gold nanorods-based dual-signal platform for accurate total antioxidant capacity assessment in food samples

Accurate assessment of Total Antioxidant Capacity (TAC) in food is crucial for evaluating nutritional quality and potential health benefits. This study aims to enhance the sensitivity and reliability of TAC detection through a dual-signal method, combining colorimetric and photothermal signals. Gold nanorods (AuNRs) were utilized to establish a dual-signal method duo to the colorimetric and photothermal properties. Fenton reaction can etch the AuNRs from the tips, as a result, a blue shift in the longitudinal LSPR absorption peak was obtained, leading to significant changes in color and photothermal effects, facilitating discrimination through both visual observation and thermometer measurements. In the presence of antioxidants, the Fenton reaction was suppressed or inhibited, protecting the AuNRs from etching. The colorimetric and photothermal signals were therefore positively correlated with TAC levels, enabling dual-signal detection of TAC. The linear range of AA was 4–100 μM in both colorimetry and photothermal modes, with detection limits of 1.60 μM and 1.38 μM, respectively. This dual-signal approach achieves low detection limits, enhancing precision and sensitivity. The method thus has the potential to act as a promising candidate for TAC detection in food samples, contributing to improved food quality and safety assessment.

Fluorescent-colorimetric dual signal ratio sensor with AuNRs@UCNPs superstructure nanoprobe for accurate hypochlorite detection

There is a significant need for sensitive and selective hypochlorite (ClO-) detection in rheumatoid arthritis, especially at the site of inflammation. However, the traditional single signal strategy based on visible emission cannot meet sensitive and accurate analysis requirements in practical applications. In this work, a novel fluorescent-colorimetric dual-signal ratio luminescent nanoprobe (superstructure AuNRs@UCNPs) was developed based on Förster resonance energy transfer (FRET) between the ClO- responsive gold nanorods (AuNRs) and lanthanide doped up-conversion nanoparticles (UCNPs). ClO- gradually etched AuNRs to produce corresponding color changes and plasmon resonance absorption peak shifts. The luminescence at 650 nm of UCNPs gradually recovered, while the luminescence at 540 nm gradually weakened. It allows for the sensitive and accurate detection of ClO- with excellent limits of detection (0.156 μM for the fluorescent ratio method and 0.231 μM for the colorimetric method). It provides a powerful dual guarantee for ClO- detection. The detection in serum of actual samples shows that the probe has reasonable accuracy and precision.

Phonon Polaritons Launched by Natural Boron Nitride Wrinkles Probed with Nano‐Fourier Transform Infrared Spectroscopy

Nano‐fourier transform infrared spectroscopy (FTIR) is a powerful tool to measure optical and electronic properties of materials at the nanoscale. It is especially useful for visualizing plasmon and phonon polaritons launched from edges of a sample or structures on top of it. Herein, an exfoliated hexagonal boron nitride flake with a thickness of ≈16 nm is transferred onto a gold substrate. The flake is characterized by micro‐Raman and nano‐FTIR spectroscopy. The Raman spectra show no difference between points on the flat surface and points on the wrinkles of the flake. Nano‐FTIR spectra, while comparable to conventional infrared spectra on the flat surface, show a strong change in the form of a second absorption peak appearing near a wrinkle in the flake. This second absorption peak shifts to higher wavenumber and becomes more intense as the probed spot gets closer to the wrinkle. This is consistent with the behavior of phonon polaritons when approaching the scattering point that is reflecting them.

Effects of isotropic stress on the band structure elastic, optical, thermal, and x-ray diffraction properties of TiSnO3.

Cubic perovskite titanium stannous oxide (TiSnO3) is a promising material for various applications due to its functional properties. However, understanding how these properties change under external stress is crucial for its development and optimization. This study employed density functional theory calculations to investigate the structural, electronic, optical, thermal, and mechanical properties of TiSnO3 under varying degrees of external static isotropic stress (0-120 GPa). The study reveals a significant decrease in the bandgap of TiSnO3 with increasing stress due to lattice modifications and the formation of delocalized electrons. Partial density of states analysis indicates that Sn and O states play a key role in shaping the electronic band structure. TiSnO3 exhibits increased light absorption with stress, accompanied by a blue shift in absorption peaks, whereas, both polarizability and refractive index decrease with increasing stress. Mechanically, all elastic moduli (bulk, shear, and Young's) show an increase under stress, signifying a stiffening response of the material under stress. Similarly, the Pugh ratio suggests a transition from ductile to brittle behaviour at elevated stress levels. Phonon dispersion calculations indicate the instability of the cubic phase at 0 K. However, a phonon gap emerges at 30 GPa and widens with increasing stress. X-ray diffraction further supports these findings by demonstrating a shift in diffraction peaks towards higher angles with increasing stress, consistent with the applied stress. In conclusion, this computational study offers a thorough understanding of how external stress influences the properties of TiSnO3, providing valuable insights for potential applications in various fields.

The effect of micro-nanostructural changes on the absorption and emission characteristics of InGaAsP photocathodes

In this paper, three structures (cylinder, square column, and hexagonal prism) of InGaAsP nanowire arrays are designed based on the excellent light trapping effect of nanostructures. The effects of nanowire aperture, array period, and nanowire height on the light absorption properties are simulated and analyzed using the finite-domain time-difference (FDTD) method. The photoelectron emission capacity of the nanowire arrays was also calculated using MATLAB. The results show that the cylindrical nanowire array has phenomenon of resonance enhancement (absorption peak) in the near-infrared band of 820–1000[Formula: see text]nm, and the shift of absorption peaks can be achieved by adjusting the geometric parameters. Meanwhile, the quantum efficiency is taken to 9.98%. These simulation results provide some reference for the photocathode design of InGaAsP in the near-infrared band.

Biomaterials in Cancer Therapy: Investigating the Interaction between Kaempferol and Zinc Ions through Computational, Spectroscopic and Biological Analyses.

A complex of the natural flavonoid kaempferol with zinc (Kam-Zn) was synthesized, and its physicochemical properties were investigated using spectroscopic methods such as Fourier transform infrared spectroscopy (FT-IR), ultraviolet-visible (UV-Vis) spectroscopy and theoretical chemistry. Biological studies were conducted to evaluate the cytotoxic and antiproliferative effects of these complexes on MCF-7 breast cancer cells. Treatment with Kam 100 µM (84.86 ± 7.79%; 64.37 ± 8.24%) and Kam-Zn 100 µM (91.87 ± 3.80%; 87.04 ± 13.0%) showed no significant difference in proliferation between 16 h and 32 h, with the gap width remaining stable. Both Kam-Zn 100 μM and 200 μM demonstrated effective antiproliferative and cytotoxic activity, significantly decreasing cell viability and causing cell death and morphology changes. Antioxidant assays revealed that Kam (IC50 = 5.63 ± 0.06) exhibited higher antioxidant potential compared to Kam-Zn (IC50 = 6.80 ± 0.075), suggesting that zinc coordination impacts the flavonoid's radical scavenging activity by the coordination of metal ion to hydroxyl groups. Computational studies revealed significant modifications in the electronic structure and properties of Kam upon forming 1:1 complexes with Zn2+ ions. Spectroscopy analyses confirmed structural changes, highlighting shifts in absorption peaks and alterations in functional group vibrations indicative of metal-ligand interactions. FT-IR and UV-Vis spectra analysis suggested that Zn coordinates with the 3-OH and 4C=O groups of ligand. These findings suggest that the Kam-Zn complex exhibits interesting antiproliferative, cytotoxic and modified antioxidant effects on MCF-7 cells, providing valuable insights into their structural and anticancer properties.

SrO–ZnO–PbO–B2O3 glassy insights: Unveiling the structural and optical features for gamma ray shielding efficacy

The melt-quenching approach was utilised to synthesize amorphous SrO–ZnO–PbO–B2O3 glasses, with FTIR spectroscopy applied to the samples to reveal the various bonds' stretching and bending vibrations. With PbO introduced to the network, the UV–Vis absorption spectrum's absorption peak shifts towards the higher wavelength values, while Tauc plot analysis of the UV–Vis spectra reveals a 2.957–2.569 eV decrease in the band gap energy. The radiation shielding properties are examined via Phy-X program. The mass attenuation coefficient (MAC) has an inverse relation with the energy, which demonstrated the greater penetration ability of radiation that contains higher energy. In terms of the MAC values at low energies the results revealed a greater difference, while they are almost identical at higher energies. The linear attenuation coefficient (LAC) was evaluated and the chemical composition's influence discussed, with the LAC values in the order of SZPB1 <SZPB2 <SZPB3 <SZPB4. This confirms that the PbO addition leads to increased LAC values. The half value layer (HVL) decreases with increased concentration of PbO. This suggests that the higher the glass system's PbO content, the thinner the glass system needs to be to attenuate half of the incoming photons.

Investigation of electrochemical and photoluminescence properties of Dy[formula omitted] doped SrO/BaO/Al2O3 nanocomposite for supercapacitor and display applications

The current study investigates the synthesis and characterization of dysprosium-doped strontium barium aluminum nanocomposites (SBAD NCs), aiming to enhance their suitability for display and supercapacitor applications. SBAD NCs are synthesized by Solution combustion synthesis using aloevera extract as a reducing agent. Multi-phase formation of NCs due to SrO, BaO, and γ-Al2O3 phases was confirmed by PXRD analysis, and crystallite size is found to be in the range of 26 nm to 36 nm. SEM analysis confirmed the surface morphology and the elemental composition was affirmed by the EDAX spectrum which confirmed the purity of the synthesis. The blue shift in the UV–visible absorption peak with increasing dopant concentration suggests a rise in the direct energy band gap from 4.07 eV to 4.11 eV. FTIR analysis confirmed functional groups and fingerprint region affirmed the presence of SrO, BaO, and AlO bonds. Photoluminescence analysis performed under excitation wavelength 276 nm revealed a prominent emission peak at 565 nm, and the CIE values fall in the yellow-green region of visible spectra. The CCT value was found to be 4490 K–4542 K which might find an application as a nanophosphor in cool light-emitting diodes. The tailored nanocomposites exhibit exceptional electrochemical performance characterized by superior specific capacitance, and improved charge–discharge kinetics, as evaluated through cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The specific capacitance is found to be in the range of 103.26 F/g to 173.24 F/g at a scan rate of 10 mV/s with increasing Dy3+ dopant concentration from 1 mol% to 9 mol% respectively. The dysprosium-doped SBAD NCs emerge as promising candidates for high-performance energy storage systems and vibrant display technologies, offering a synergistic integration of efficient energy storage and vivid display functionalities.

Mechanochemical Synthesis of Chromium(III) Complexes Containing Bidentate PN and Tridentate P-NH-P and P-NH-P' Ligands.

Chromium(III) complexes bearing bidentate {NH2(CH2)2PPh2: PN, (S,S)-[NH2(CHPh)2PPh2]: P'N} and tridentate [Ph2P(CH2)2N(H)(CH2)2PPh2: P-NH-P, (S,S)-(iPr)2PCH2CH2N(H)CH(Ph)CH(Ph)PPh2: P-NH-P'] ligands have been synthesized using a mechanochemical approach. The complexes {cis-[Cr(PN)Cl2]Cl (1), cis-[Cr(P'N)Cl2]Cl (2), mer-Cr(P-NH-P)Cl3 (3), and mer-Cr(P-NH-P')Cl3 (4)} were obtained in high yield (95-97%) via the grinding of the respective ligands andthe solid Cr(III) ion precursor [CrCl3(THF)3] with the aid of a pestle and mortar, followed by recrystallization in acetonitrile. The isolated complexes are high spin. A single-crystal X-ray diffraction study of 2 revealed a cationic chromium complex with two P'N ligands in a cis configuration with P' trans to P' with chloride as the counteranion. The X-ray study of 4 shows a neutral Cr(III) complex with the P-NH-P' ligand in a mer configuration. The difference in molecular structures and bulkiness of the ligands influence the electronic, magnetic, and electrochemical properties of the complexes as exhibited by the bathochromic shifts in the electronic absorption peaks of the complexes and the relative increase in the magnetic moment of 3 (4.19 μβ) and 4 (4.15 μβ) above the spin only value (3.88 μβ) for a d3 electronic configuration. Complexes 1-4 were found to be inactive in the hydrogenation of an aldimine [(E)-1-(4-fluorophenyl)-N-phenylmethanimine] under a variety of activating conditions. The addition of magnesium and trimethylsilyl chloride in THF did cause hydrogenation at room temperature, but this occurred even in the absence of the chromium complex. The hydrogen in the amine product came from the THF solvent in this novel reaction, as determined by deuterium incorporation into the product when deuterated THF was used.

Enhanced solubility and biological activities of Flufenamic acid through β-Cyclodextrin derivatives inclusion complexes: A comprehensive study

This study explores the formation of inclusion complexes between the solubility enhancement of Flufenamic acid (FNA) and various β-Cyclodextrins (β-CD, Hβ-CD, Mβ-CD, and Sβ-CD) using ultrasonic probe sonication method. The investigation encompasses a multi-faceted analysis, employing UV–Visible, FTIR, XRD, FE-SEM, TGA-DSC techniques and molecular docking studies. The UV–Visible spectra reveal absorption peak shifts and binding constants (Ka) indicate interaction strength, and thermodynamic parameters suggest spontaneous and favorable inclusion processes of β-CDs:FNA. Solid inclusion complexes of β-CDs:FNA were further characterized using FTIR, revealing alterations in functional groups indicative of complex formation. XRD analysis elucidates changes in crystallinity, while FE-SEM provides insights into morphological variations. Thermal stability is assessed through TGA-DSC, demonstrate the impact of inclusion on the complexes stability. Phase solubility diagrams illustrate the improved solubility of FNA in the presence of β-CDs. Mβ-CD:FNA exhibits the highest stability constant (1204 M−1), emphasizing its potential as an effective carrier. The binding energy of Mβ-CD:FNA (−46.72 kcal/mol) was lower than that of β-CD:FNA (−39.03 kcal/mol), Hβ-CD:FNA (−46.40 kcal/mol), and Sβ-CD:FNA (−46.29 kcal/mol), indicating that the hydroxypropyl group substitution enhanced the inclusion ability of β-CDs. Antibacterial activity studies against S. aureus and E. coli highlight enhanced efficacy of inclusion complexes with Mβ-CD:FNA (92.3 ± 0.18 % and 94.2 ± 0.17 %) demonstrating superior antibacterial activity. Cytotoxicity evaluations on HCT-116 cells reveal the safety profile of the β-CDs:FNA inclusion complexes, with Mβ-CD:FNA showing lower toxicity and high cell internalization compared to other formulations. The findings hold promise for applications in drug delivery, antimicrobial packaging, and the broader pharmaceutical and biotechnological fields.

Hydrocolloid-based nutraceutical delivery systems: Potential of κ-carrageenan hydrogel beads for sustained release of curcumin

This study investigates the potential of κ-carrageenan hydrogel beads as a delivery system for curcumin, a bioactive compound with various health benefits. Hydrogel beads were prepared using the extrusion technique with a hypodermic needle. The encapsulation efficiency of curcumin in the κ-carrageenan hydrogel beads was found to be 74.61 ± 3.2 %. FTIR spectroscopy analysis revealed shifts in absorption peaks, indicating possible hydrogen bonding and/or ionic interactions between the polymer and salt. An increase in the melting point of curcumin, by 25 °C, in curcumin- κ-carrageenan beads suggests the heat protection offered by the carrageenan chains to curcumin molecules. The in vitro release of curcumin from the beads suggests a sustained and pH-dependent release nature. The release kinetics follow the first order and the Korsmeyer-Peppas model. The outcome offers value-added delivery systems of bioactive compounds toward developing novel food and pharmaceutical applications.

Nested graphene disks patterned THz wave absorber: Bio sensing vision

A three-layer adjustable THz wave absorber is introduced in this paper. The structure's geometry is heavily based on a combination of periodic graphene disks and their complementary patterns. Also, the middle layer is considered an air gap while the graphene patterns are stacked into TOPAS filler. Additionally, a golden back reflector is placed at the bottom of the absorber to ensure a blocked transmission channel. This configuration is modeled exclusively by passive circuit elements, while full wave simulation is also performed. Also, a simple genetic-based algorithm is exploited to optimize design parameters in numerical values, including geometrical and stimulation values. In addition, a mechanical tuning setup is suggested that can interestingly change absorption peaks. The frequency shift of absorption peaks can be up to 5 THz, which makes the proposed absorber an ideal basic building block for several applications ranging from sensing to indoor communication. Furthermore, the discussion section explains the potential applications of the proposed absorber for bio-sensing by filling the air gap with biological samples.

Effect of UHT Thermal Treatment on the Secondary Structures of Milk Proteins: Insights From FTIR Analysis and Potential Allergenic Activity.

Although thermal treatments are beneficial for the preservation and safety of milk, they can also alter its immunogenic activity by affecting its protein components. To achieve precise results, it is essential to identify the specific proteins that cause food allergies. Therefore, investigating the possible alterations of cow's milk proteins (CMPs) resulting from thermal treatments is necessary. In this study, the Fourier transform infrared spectroscopy (FTIR) technique was used to analyze the effect of UHT thermal treatment on the secondary structures of milk casein. Using the second derivative, six characteristic peaks were identified in the Amide I region, ranging from 1700 to 1600 cm-1. It was found that thermal treatments produce shifts in absorption peaks, indicating changes in protein conformation and possibly in allergenic activity. These shifts were clearly identified in the first characteristic peak of samples M8 and M9, from 1621 to 1600 cm-1. The results suggest that thermal treatments may promote protein aggregation by increasing β turns and reducing β sheets and α helices, which could enhance the allergenic potential of the proteins and facilitate the formation of complexes between different milk proteins, such as β-lactoglobulin and κ-casein. Further studies are needed to experimentally validate the allergenic activity of proteins modified by thermal treatments, as only an analytical method (FTIR) was used to evaluate the secondary structures of the proteins.