This research presents a comprehensive investigation into the development of advanced asphalt materials fortified with PF/OMMT nanocomposites, emphasizing the synergistic effects of melt blending and nano intercalation. Through meticulous characterization, including SEM, FT-IR, and XRD analyses, the study unveils the microstructural evolution, affirming the formation of highly oriented interlayer structures within the asphalt matrix. The incorporation of OMMT, known for its hydrophobicity, significantly enhances the interfacial interactions between PF and asphalt, thereby bolstering the material's mechanical resilience, specifically its tensile, shear, and high-temperature rutting resistance properties. The presence of PF imparts notable improvements in the asphalt's thermal stability and aging resistance, attributed to its inherent antioxidative properties and the establishment of a robust three-dimensional polymer network with OMMT. These advancements herald a promising avenue for the production of high-performance, durable asphalt with superior anti-aging characteristics, optimized for demanding environmental conditions and heavy-duty applications.