A higher-order shear deformable model is extended in this paper for static analysis of a sandwich cylindrical panel composed of porous core sandwiched by graphene-reinforced copper matrix. Principle of virtual work is used to derive governing equations of static bending through the computation of strain energy and external work. A higher-order shear deformable model is used to develop the kinematic relations. The sandwich cylindrical panel is subjected to mechanical and thermal loads. The governing equations are solved using Eigenvalue–Eigenvector method for clamped–clamped boundary conditions. The eigenvalues of the characteristic equation are obtained, and the solution is obtained for real and complex roots. The boundary conditions are applied to obtain integration constants. The axial and radial variation of the displacement, strain, and stress components are presented in terms of significant input parameters such as volume fraction, and folding angle of the graphene origami, various distribution patterns, porosity coefficient, thermal and mechanical loads, and geometric parameters. The results indicate that the stress, strain, and deformation components are increased with an increase in porosity coefficient and folding angle of the graphene. Furthermore, an enhancement in the volume fraction of the graphene leads to a significant decrease in various stress, strain, and deformation components. The results of this work can be used in aerospace science and technology specially in airplanes.