Several years ago, the razor blade was introduced as an alternative device for performing the shave removal and/or biopsy of skin lesions. Though inexpensive and readily available, the razor blade is somewhat cumbersome to use and poses a risk for accidental injury to the practitioner. We describe a modification of the razor blade shave biopsy procedure utilizing an innovative adaptor design. A comparison of the adaptor-designed shave biopsy instrument to the standard razor blade device is made. The modifications implemented in the adaptor design serve to enhance the comfort of performing biopsies, minimize accidental injury, help save time, and provide for a more professional appearing way in which to obtain skin specimens. The new adaptor design helps to facilitate the safe and effective use of the razor blade in dermatologic practice.