Objective To explore the prevalence and epidemic characteristics of overweight, obesity, and central obesity in Shanghai Pudong New Area. Methods Multi-stage stratified random sampling method was conducted in Pudong New Area in 2013. Residents over 15 years old were randomly selected from 13 communities and participated in the cross-sectional study. A structured questionnaire was used to collect the information and physical examination, biochemical assays were also conducted. SPSS 20.0 was used to analyze the results. Results The average body mass index of participants was(25.04±3.79)kg/m2 and the average waist circumference was(82.44±9.51)cm. The prevalences of overweight, obesity, and central obesity were 41.67%, 17.70%, and 31.32% respectively. Standardized prevalences of overweight, obesity, and central obesity were 34.39%, 16.96%, and 25.66% respectively, according to 2010 national age composition of population. Statistically significant sex differences were found among the prevalence of overweight, obesity, and central obesity groups(all P<0.05). The prevalence of central obesity in female was raised by increasing age. Residents with hypertension, hyperglycemia, dyslipidemia, and metabolic disorders had higher prevalences in overweight, obesity, and central obesity(all P<0.05). Conclusion The prevalences of overweight, obesity, and central obesity among the residents in Shanghai Pudong New Area were relatively high. Relevant risk factors should be explored to promote health education that may enhance people's awareness of weight management. (Chin J Endocrinol Metab, 2016, 32: 206-212) Key words: Overweight; Obesity; Central obesity; Cross-sectional study