Sexual Life Of Patients Research Articles

Ulipristal acetate on quality of life and sexual function of women with uterine fibromatosis

To evaluate quality of life and sexual function of childbearing-age women, affected by uterine fibromatosis undergoing medical treatment with ulipristal acetate. The data obtained by filling the questionnaires European Quality of Life Five-Dimension Scale and modified Female Sexual Function Index, were analyzed to assess UPA usefulness in improving QoL and sexual activity. A total of 139 patients affected by uterine fibromatosis undergoing conservative ulipristal acetate treatment were enrolled in this prospective observational cohort study. Seventy-one women (average age 46.5 years) answered the questionnaires: QoL and sexuality were evaluated before and after ulipristal acetate treatment. 59 patients (83.1%) had an improvement of QoL and general health state, with a reduction of VAS score after ulipristal acetate treatment. EQ-5D-5L showed a statistically significant improvement of usual act impairment, mobility, discomfort, anxiety/depression (p < .0005). There was no difference in personal care management after therapy. Modified FSFI showed a statistically significant improvement (p < .0001) of sexual satisfaction and sexual life. A not statistically significant improvement in dyspareunia was also highlighted. This study provides a clear picture about QoL impact on women and confirms the effectiveness of the ulipristal acetate in improving different aspects of daily and sexual life of patients undergoing medical treatment.

HP-08-006 Penile implantation as treatment option for premature ejaculation: What the patient gets?

To assess effects of penile implantation on intercourse satisfaction (IIEFQ7), overall sexual satisfaction (IIEFQ13), satisfaction with sexual relationships with partner (IIEFQ14) in patients with PE who discontinued local anesthetics (LA), PDE5i and dapoxetine. 37 patients (35-44 years old) with PE who discontinued local anesthetics (LA), PDE5i and dapoxetine due to lack of efficacy or side effects were enrolled. At baseline sexual functions were assessed by means of IIEF. 6 mo after implantation with short form of IIEF (Q7, Q13, Q14). All patients were implanted with malleable ones. Clinical effect was measured by calculating 95% CI of difference of means. t=1,993 for 0,05% and P =72. At baseline all scores were decreased as a result of negative impact of PE on sexual function (Table 1). 6 mo after implantation all of them were clinically significantly improved. Penile implantation clinically significantly improves quality of sexual life in patients with PE and should be considered as treatment option when conservative modalities are discontinued.

P798 Quality of sexual life in patients with ulcerative colitis: a monocentric observational study. On behalf of IG-IBD

P798 Quality of sexual life in patients with ulcerative colitis: a monocentric observational study. On behalf of IG-IBD

Changes in sexual life experienced by women in Taiwan after receiving treatment for breast cancer

ABSTRACT As the number of breast cancer survivors increases, these patients with sexual problems also increase. For breast cancer survivors, sexual problems are a common and painful experience. Although breast cancer survivors often encounter sexual problems, Taiwanese women are culturally conservative and patients rarely discuss sex problems with clinicians. In this study, we used qualitative methods to better understand the changes in sexual life and related care strategies for breast cancer survivors. Twenty interviews were conducted on clinical patients enrolled in hospitals that received breast cancer treatment. The data were analysed by performing a constant comparative analysis. Three themes emerged: the causes of changes in sexual life, internal response strategies and external response strategies. Ten subthemes were identified. Changes in sexual life in patients with breast cancer in this study included changes related to body image, influence of friends and family, age, genital problems, and illegal love of a partner. Breast cancer survivors can tolerate and regulate sexual life changes by adopting internal and external response strategies. Medical staff must be sensitive and must understand strategies for dealing with sexual life changes that may occur during cancer adjustment and how these strategies can help women’s well-being in the rest of their lives.

Sexual Life Traits Of Chronic Pain Disorder Patients And Relationship Between Temperament And Character Dimensions Of Personality

Objective: It is known that a complex problem is sexual life in patients with chronic pain. Also physicians may ignore this point. In this study, we aimed to compare the clinical features, sexual life properties and personality traits of patients with Chronic Pain Disorder (CPD) and healthy controls. We hypothesized that Harm Avoidance (HA) scores would be higher and predictive of compared to healthy controls also sexual dysfunction would found in patient group. Methods: This study was conducted in outpatients with CPD who presented to the Bagcilar Training and Research Hospital’s Outpatient Psychiatry Clinic. The sample was comprised of 60 outpatients (53 women, 7 men) who complained of chronic pain for at least 3 months and were not under any medication treatments. The control group comprised of 60 healthy controls (49 women, 11 men). Semi-structured sociodemographic data form, Visual Analog Scale (VAS), Temperament and Character Inventory (TCI), Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI) and Arizona Sexual Experiences Scale (ASEX) were administered to the participants. All statistical analyses were performed using SPSS for Windows, Version 23.0. Results: In CPD patients ASEX scores were significantly higher than healthy controls. It demostrates sexual dysfunction presenting in CPD group. In terms of gender; female ASEX scores were significantly higher than male ones. VAS scores did not correlate to ASEX scores in all of participants. Explatory excitability subscale of Novelty Seeking, Total Cooperativeness and Total Reward Dependence scores were changed negatively correlation with ASEX scores; Harm Avoidance, persistanceness, Self Directedness, Self Trancendance and their subscales did not correlate to ASEX scores. ASEX scores, positively corraleted to Attachment and Sentimentality subsclaes of Reward Dependence. BDI scores changed positively with BAI, ASEX,VAS scores; BAI scores also corraleted positively with VAS and ASEX scores. Helpfulness vs Unhelpfulness and Compassion vs Revengefulness subscales of cooperativeness in patients with CPD positively corraleted to ASEX scores. Conclusion: Temperament and character traits and sexual life properties of the CPD patients were significantly different from the healthy control subjects. Explatory excitability subscale of NS and C is negative predictor of Sexual Dysfunction. Also Helpfulness vs Unhelpfulness and Compassion vs Revengefulness subscale of C is positive predictor of Sexual Dysfunction.

Sexual Disorders of Patients With Metastatic Renal Cell Carcinoma (mRCC) Treated With Antiangiogenic Therapies.

Targeted therapies, in particular antiangiogenic therapies (AATs), have become the standard of treatment for metastatic renal cell carcinoma (mRCC). Although common adverse effects like fatigue have been well-established, sexual disorders induced by these treatments, although often reported, have been poorly evaluated. The aim of this study was to evaluate the impact of AATs on the sexual life of patients with mRCC and the relationships with quality of life (QoL), fatigue, and biologic parameters. This longitudinal study included patients with mRCC on first- or second-line AATs. Sexuality was evaluated by the French version of Changes in Sexual Functioning Questionnaire short-Form (CSFQ); QoL and fatigue were measured by the Functional Assessment of Cancer Therapy General (FACT-G) and the Multidimensional Fatigue Inventory (MFI-20), respectively. Biologic parameters were also assessed. Among 75 patients included in the study, 39 agreed to respond to the sexual functioning questionnaire (CSFQ). At baseline, all patients had at least 1 sexual dysfunction. No relationship with QoL, fatigue, and biologic parameters was shown. After 3 months of treatment, a decrease in at least 1 sexual dimension was observed in 69% of patients. The most affected sexual dimensions were pleasure (34%) and desire/interest (38%). No significant relationship between sexual dysfunctions and biologic parameters was found. The percentage of non-participants (50%) and the absence of a control arm are the main limitations. Patients with mRCC exhibit sexual dysfunction that could be increased by AATs independently of the impact on fatigue and QoL. Further studies aiming to define the role of biologic parameters like inflammatory markers and thyroid parameters are warranted. Sexual disorders induced or degraded by AAT are an independent side effect that should be taken into account in oncology supportive care departments.

Sexual satisfaction of patients after the resection of an epileptic focus

Abstract Objectives The resection of an epileptic focus provides a chance for seizure outcome regression, which markedly influences the level of patients' quality of life. One of its dimensions is the satisfaction with one's sexual life. Patients with epilepsy usually report low sexual satisfaction due to commonly diagnosed disturbances of sexual functions characterized by a multifactorial etiology. The aim of the study was to assess the level of satisfaction with their sexual life in patients after the surgical resection of an epileptic focus. Patients and methods The study group included 63 patients who had undergone the surgical resection of an epileptic focus in a neurosurgical ward. The study was conducted with the present authors' own tool consisting of three parts. Result The patients assessed their sexual life as moderately satisfactory (the average score was 4 out of a 7-grade scale). 38% of the respondents reported a complete withdrawal from sexual life, sporadic sexual activity or masturbatory behavior (instead of interactive behavior). This type of behavior correlates with the reduction in sexual satisfaction. Higher satisfaction is associated with initiating new behavior which is adequate to the patient's health status, more frequent sexual contacts or no changes between behavior before and after the surgery. Moreover, the removal of an epileptic focus reduced the fear of a possible seizure during intercourse. Conclusion Based on the findings it may be assumed that the sexual satisfaction of patients with epilepsy after the resection of an epileptogenic focus is markedly affected by psychological factors, which should be considered in the therapeutic process.

The Quality of Life in Patients After Surgical Treatment of a Lumbar Disc Herniation — a Preliminary Study

Introduction. Herniated intervertebral disc is a disease that is one of the main causes of sciatica and severe, sharp back pain and usually concerns adults aged 35 to 50 years.Aim. To evaluate the effect of surgical treatment on the quality of life in patients hospitalized and subjected to surgery due to a disk herniation in the lumbar spine.Material and Methods. The study included 50 patients treated surgically for disc herniation in the lumbar region. The diagnostic survey method was applied for the purposes of this study with the use of the author’s questionnaire, the Oswestry Disability Index (ODI), the SF-36 questionnaire and VAS scale. The statistical analysis of the material has been performed using the Student t-test, Shapiro–Wilk test, Wilcoxon test and Spearman and Pearson correlation test.Results. The analysis of the study material showed that before surgery all respondents experienced pain sensations of varying degree in the lumbar region, and after surgery 52% of patients experienced no pain in this region. The analysis of data obtained through the ODI showed that before surgery, the majority of respondents belonged to the group 3, while after the procedure they were in group 1.Conclusions. 1) Spinal disk disease and related pain had a negative impact on social and sexual life of patients. 2) After surgery, patients experienced significantly less pain. 3) It was observed that in patients operated for a lumbar disc herniation, the degree of disability was reduced and the quality of life increased after surgery. (JNNN 2017;6(1):4–10)

Ectopic Reservoir During Inflatable Penile Implant Surgery: Is It Now Standard of Care?

The implantation of a three-piece inflatable penile prosthesis represents the gold standard treatment to restore a normal sexual life in patients with refractory erectile dysfunction. For simplicity, the reservoir of the penile implant traditionally has been placed in an “orthotopic” position in the space of Retzius through a blind puncture of the external inguinal ring once the bladder has been emptied to minimize the risk of inadvertent perforation. Although relatively uncommon, complications related to orthotopic reservoir placement include bladder, bowel, or vascular injury. This is particularly risky in patients who have undergone previous major pelvic surgery in which the planes that separate the peritoneal cavity from the space of Retzius have been obliterated.1,2 In this situation after pelvic surgery, to avoid this unnecessary risk, it has been common practice to position the reservoir under direct vision through a separate abdominal incision. To obviate a second incision with its associated morbidity and increased operative time, Wilson et al3 described the submuscular reservoir placement through a penoscrotal incision in 2002. According to this technique, the reservoir is placed “ectopically” through the external inguinal ring into the rectus sheath, posteriorly to the rectus abdominis muscle but above the fascia transversalis, and therefore well away from the Retzius space and the pelvic viscera.

Effects of Onabotulinum Toxin A Intradetrusor Injections on Urinary Symptoms and Sexual Life in Women Affected by Multiple Sclerosis: A Prospective Controlled Study

Background: Voiding and sexual dysfunction in Multiple Sclerosis represent the most devastating dimensions of the disease. Pharmacological treatment of voiding dysfunction could improve sexual life in patients affected by the disease. We investigated the effects of Onabotulinum toxin A intradetrusor injections on urinary symptoms and sexual dysfunction, and on the psychological status of women affected by Multiple Sclerosis with refractory overactive bladder. Methods: 41 patients underwent neurologic and urologic clinical evaluations and were administered the Female Sexual Function Index, the Incontinence-Quality of Life questionnaire, the Hamilton Anxiety Rating Scale and the Hamilton Depression Rating Scale, before and six months after Onabotulinum toxin A intradetrusor injection; 21 continent females affected by the disease acted as controls. Results: At baseline, all patients were incontinent and 35/41 was sexually active, with low Female Sexual Function Index scores. Mild depression and anxiety were detected in all cases with a reduced quality of life. Six months after treatment, overactive bladder symptoms improved significantly in all patients. Arousal, lubrication, orgasm-related problems and desire alterations markedly improved, together with an improvement in anxiety, depression and quality of life. Scores of Female Sexual Function Index, Incontinence-Quality of Life questionnaire, Hamilton Anxiety Rating Scale and Hamilton Depression Rating Scale remained unchanged in controls. Conclusion: Onabotulinum toxin A intradetrusor injections not only control overactive bladder symptoms in women affected by multiple sclerosis, but also significantly improve sexual life.

58 - Assessing sexual life in patients with double J stent

58 - Assessing sexual life in patients with double J stent

Sexual Well-Being in Patients with Blepharospasm, Spasmodic Torticollis, and Hemifacial Spasm: A Pilot Study.

Mood, anxiety, and other psychological symptoms are common in dystonic patients suffering from blepharospasm (BSP) and spasmodic torticollis (ST). Since sexual well-being is an important aspect of mental health, here, we investigated whether these patients may also experience a worsening of their sexual life. In particular, quality of sexual life was evaluated in patients suffering from BSP (N = 30), ST (N = 30), and in a control group of patient with Hemifacial spasm (HFS; N = 30), undergoing botulinum toxin type A therapy. A group of 30 age-matched healthy volunteers constituted an additional control group. Patients were evaluated just before the periodic injection of botulinum toxin. Sexual functioning was assessed using the Sexual Functioning Inventory, a reduced form of the Golombok Rust Inventory, previously employed in patients with Parkinson’s disease. Depression (Beck Depression Inventory) and anxiety (STAI-X1/X2) were also assessed. Results revealed that sexual functioning was significantly affected in patients with BSP, ST, and HFS with respect to healthy controls. Dystonic patients manifested more sexual dysfunction than patients with HFS. Overall, females had a poorer quality of sexual life than males and, among females, women with BSP were the most dysfunctional. Psychological symptoms were present in patients with dystonia, but not in patients with HFS. As discussed in the paper, several factors might be taken into account to explain worse quality of sexual life in patients with dystonia compared to patients with hemifacial spasm. Among them an important role might be played by the central origin of dystonia pathophysiology (i.e., altered activity of cortico-striato-thalamic-cortical circuits). Future investigations are necessary to further explore these preliminary findings, considering that this is the first time that sexual well-being is evaluated in patients with BSP, ST, and HFS, and comparable data are not available.

Rhodiola rosea, folic acid, zinc and biotin (EndEP®) is able to improve ejaculatory control in patients affected by lifelong premature ejaculation: Results from a phase I-II study.

The therapeutic armamentarium currently available for the treatment of premature ejaculation (PE) is not highly satisfactory. However, phytotherapeutics appear to be an interesting option for PE management. The present study aimed to evaluate the tolerability and efficacy of a phytotherapeutic combination of Rhodiola rosea, folic acid, biotin and zinc (EndEP®) in the treatment of patients affected by lifelong PE. All patients affected by lifelong PE who were attending three Urological Institutions from July to December 2014 were enrolled in this prospective, multicentre, phase I–II study. All patients were assigned to receive oral tablets of EndEP® (one tablet per day) for 90 days. Clinical and instrumental analyses were carried out at enrolment and at the end of the study. International Prostatic Symptom Score (IPSS), International Index of Erectile Function (IIEF)-15, Premature Ejaculation Diagnostic Tool (PEDT) and Short Form (SF)-36 questionnaires were used. The intravaginal ejaculation latency time (IELT) for each event was also evaluated using the stop-watch technique. The main outcome measure was the difference from baseline in PEDT questionnaire and mean IELT at the end of the follow-up period. In total, 91 patients (mean age, 32.3±5.6 years) were analysed. The baseline questionnaires mean scores were 1.1±1.6, 26.1±2.9, 15.3±3.4 and 98.2±0.5, for IPSS, IIEF-15, PEDT and SF-36, respectively. The mean IELT at baseline was 73.6±46.9s. At the follow-up examination (90 days after the start of treatment), no statistically significant differences were identified in terms of IPSS (1.4±1.5) or IIEF-15 (26.3±3.1) compared with the pre-treatment values (P=0.19 and P=0.64, respectively). A statistically significant difference was detected between the mean IELT at enrolment and after treatment (73.6±46.9 vs. 102.3±60.0; P<0.001) and SF-36 questionnaire (98.2±0.5 vs. 99.4±0.1; P<0.001). Fifty-five patients reported improvement in the control of ejaculation (60.4%). Very few adverse events were reported (4.4%). In conclusion, it was found that EndEP® significantly improved ejaculatory control and the quality of sexual life in patients affected by lifelong PE, with a very low rate of adverse events.

Calidad de vida sexual en pacientes con diagnóstico de cáncer de mama y cáncer de cuello uterino

Several researchers in Medicine, Sociology and Psychology have tried to solve the following question: What is the quality of sexual life in patients diagnosed with breast cancer and / or cervical cancer? There is no single answer, but there is a consensus that these diseases produce deep traces of a psychological, physical and sexual nature in the woman and in her partner, so this situation constitutes, without a doubt, one of the greatest challenges in managing comprehensive of patients.

Quality of Sexual Life among Patients with Genital Lichen Sclerosus

Objective: To evaluate the quality of sexual life in patients with genital lichen sclerosus (LS) recruited in a trial aimed to assess the efficacy of innovative surgical treatments. Design and Method: The Index of Sexual Satisfaction (ISS) questionnaire was used. The Brief Pain Inventory (BPI) was also used to assess the level of pain/discomfort and the grade of interference of LS in daily activities, social relationships, happiness, mood and sleeping. Patients were evaluated at baseline, 4,12, and 24 weeks after treatment. Results: From May 2014 to December 2015, 74 heterosexual patients (52 men, 70.3%, median age 52, IQR: 37-68; 22 women, 29.7%, median age 59.2, IQR: 42-73) with genital LS were evaluated. Fifty-nine patients (79.7%) were sexually active; among these, 45 (76.3%) were in a stable sexual partnership. Overall, 56 patients (75.7%) reported a high degree of genital pain/discomfort, particularly the female patients (18/22, 81.8%), and measurable interferences in selected wellbeing dimensions, such as mood balancing and social relationships. Overall, 49 patients (66.2%) had a current/history of secondary sexual disorders after the onset of LS; dyspareunia (32/49, 59.1%) and desire disorders (8/49, 16.3%) were reported; vulvodinia (5/22, 22.7%), and erectile dysfunction (4/32, 12.5%) were also experienced. Over two-thirds of the sexually active patients who were in a stable partnership (31/45, 68.9%) declared a decrease in the number and quality of sexual intercourses per month. Conclusions: LS affects dramatically the quality of sexual life and secondary sexual disorders are very frequent among LS patients. Thus, a sexological support is needed for this population.

Influence of sexual function intervention on quality of sexual life for patients after LuohuII surgery

Objective The Female Sexual Function Index (FSFI) was used to investigate the sexual life quality of patients who got laparoscopic peritoneal vaginoplasty of LuohuⅡ, so as to take measures to improve patients postoperative quality of life. Methods A total of 106 cases undergoing laparoscopic peritoneal vaginoplasty of LuohuⅡ were selected from January 2012 to March 2013.All patients got the questionnaire survey by FSFI and the FSDS-R questionnaire to evaluate the sexual function and psychological states. According to the existing problems, the intervention measures and health guidance were given to patients. And one year after surgery, their sexual function was evaluated again. Results The length of vagina was (12.29±1.67) cm, which was significantly longer than before (t=2.825, P<0.05). The sexual desire, sexual arousal, sexual orgasm, sexual satisfaction, sexual pain and total score of FSFI were (4.0±0.4), (4.2±0.4), (4.5±0.5), (4.1±0.7), (5.0±0.5), (4.6±0.5) and (29.7±1.2), which were significantly better than those before (t=7.64, 3.77, 6.27, 8.14, 8.78, 7.92, 36.13, respectively; P<0.01). Conclusions The sexual satisfaction of patients is increased after intervention. The patients with laparoscopic peritoneal vaginoplasty generally have sex problems and lack of the confidence, and effective intervention can improve the sexual life quality and satisfaction, as well as self-confidence of patients. Key words: Laparoscopic peritoneal vaginoplasty; LuohuⅡ; Quality of sexual life; Satisfaction

Systematic review: treatment of atrophic vaginitis in breast cancer patients treated with aromatase inhibitors

The objective of this study was to determine the body image and sexual life of patients who treated with chemotherapy after mastectomy. The research was carried out between 5th September and 30th December 2014 at Ordu State Hospital in the chemotherapy unit as a cross-sectional and descriptive study. The data was collected with questionnaire including descriptive feature and The Medical Outcomes Body Image scale and Sexual Experiences scale. Statistical analyseswere evaluated via Statistical Package for Social Sciences (SPSS) software program 15.0 for data entry and analysis. 33 female patients accepted participating in the study. The mean age of the women was 48.69, and all women married. 54.5% of women were primary school graduates. The mean age of the women husbands were 51.45% and 45.5% primary and secondary school graduates. Ofwomen treatedwith chemotherapywere body image average 88.03, sexual experiences scale average 17.03. These two results show that, inwomen receiving chemotherapy due to mastectomy had found to be in moderate (88.03±23.80), and their about sexual experiences have proved to be a little reluctant (17.03±10.40).

Prolactin promotes T47D cell motility through actin cytoskeleton

The objective of this study was to determine the body image and sexual life of patients who treated with chemotherapy after mastectomy. The research was carried out between 5th September and 30th December 2014 at Ordu State Hospital in the chemotherapy unit as a cross-sectional and descriptive study. The data was collected with questionnaire including descriptive feature and The Medical Outcomes Body Image scale and Sexual Experiences scale. Statistical analyseswere evaluated via Statistical Package for Social Sciences (SPSS) software program 15.0 for data entry and analysis. 33 female patients accepted participating in the study. The mean age of the women was 48.69, and all women married. 54.5% of women were primary school graduates. The mean age of the women husbands were 51.45% and 45.5% primary and secondary school graduates. Ofwomen treatedwith chemotherapywere body image average 88.03, sexual experiences scale average 17.03. These two results show that, inwomen receiving chemotherapy due to mastectomy had found to be in moderate (88.03±23.80), and their about sexual experiences have proved to be a little reluctant (17.03±10.40).

Effect of laparoscopic nerve-sparing radical hysterectomy on bladder function, intestinal function recovery and quality of sexual life in patients with cervical carcinoma.

To investigate bladder and intestinal function recovery and quality of sexual life after laparoscopic nerve-sparing radical hysterectomy (LNRH) for treatment of early invasive cervical carcinoma. Subjects included patients who underwent radical hysterectomy by laparotomy who were randomly assigned to 2 groups: 30 patients who underwent LNRH and 35 classical laparoscopic radical hysterectomy (LRH). We assessed the patients general clinical information, surgical characteristics, pathological findings, and adjuvant therapies. A urodynamic study was used to assess bladder function. Intestinal function recovery and quality of sexual life were evaluated by questionnaire. No significant differences were found in age, surgery characteristics, pathological findings, adjuvant therapies, and main adverse effects between the 2 groups. The mean duration of the postoperative catheterization (DPC) in group LNRH was shorter than that in group LRH (P < 0.001). The maximum flow rate, maximum cystometric capacity , maximum detrusor pressure and urinary complications in group LNRH were better than those in group LRH. The quality of sexual life evaluated according to the female sexual function index (FSFI) was better in group LNRH than in those who underwent LRH. The intestinal function of patients in group LNRH also recovered better compared with patients in group LRH.

SAT0429 Sexual life is more perturbed in men than women suffering from chronic low back pain. Rsults of a cross sectional study in a moroccan sample

BackgroundChronic Low Back Pain (CLBP) is a major public health problem responsible of disability and use of health services. Sexual difficulties in CLBP patients seem to be wide-ranging and probably...