During the past decade, a number of studies have dealt with endocrine testicular function in older men, but information on seminal parameters in senescence has remained scanty. This fact prompted the present authors to initiate a study evaluating the exocrine and endocrine functions in older men. Twenty-three men participated in the study. Their ages ranged from 60 to 88 years, the mean being 67 ± 7.8 (SD) years. All had children and 22 of them had grandchildren. Twenty younger men, 24 to 37 years old (mean, 29.2 ± 3.2 years) served as a control group. Each of them had fathered at least one child. Figure 1 shows the sexual activity of both groups. Figures 2 to 6 illustrate the seminal parameters of the two groups. No differences were observed in ejaculate volume or sperm morphology between the young and the older men. Similarly, the fertilizing capacity of sperm as assessed by the HOP test did not differ between the groups, although sperm counts were higher and motility and fructose were lower in the older men. It was possible to demonstrate significant correlations between age and sperm motility in all subjects investigated (r = 0.4843; P < 0.001) and between sexual intercourse episodes per month and sperm motility (r = 0.4908; P < 0.01), as well as sperm density (r = 0.3998; P < 0.05). In the older group of men, it was not possible to determine any significant trend between age and any other parameter.