Background: Cervical cancer affects all aspects of a patient’s life, including sexualfunctioning and intimacy. Sexuality is one of the indicators of quality of life; it influencesthoughts, feelings, actions, social integration, and therefore, physical and mental health. Thepresent study aimed to evaluate the impact of protocol of nursing intervention on sexualdysfunction among women with cervical cancer. An intervention study design wasconducted in out-patient clinic in the oncology unit at Beni-suef university Hospital. Apurposive sample of 70 women was included in the study. A quasi-experimental (prepost) study design was used. Data was collected through four types of tools structuredinterviewing questionnaire sheet, female sexual function index, female sexual distress scaleand body image scale. In addition to Supportive material (educational booklet) was given towomen. Results: There were high statistical significant differences in the women's totalscore of knowledge about cervical cancer, total scores of female sexual function index,female sexual distress scale and body image scale at post intervention in which the womenhad higher score at post intervention p (< 0.001). Conclusion: Educational booklet provedto have a positive effect on knowledge and sexual function of women with cervical cancer.Recommendations: Multidisciplinary collaboration approach for addressing sexualproblems related to cervical cancer, preparing health classes for cervical cancer womenregarding sexual dysfunction with cervical cancer and further research about nurse'sperception and practices regarding sexual dysfunction with cervical cancer.