Gender Differences Research Articles

Gender differences in organizational fairness, diversity and inclusion: the mediating role of psychological safety in affective commitment

PurposeThe current study explores the role of social psychological factors on organizational commitment. It examined the relationships between organizational fairness, inclusion, diversity, sexism, psychological safety and affective commitment.Design/methodology/approachThe study adopted a cross-sectional survey method where data were collected from staff across six higher education institutions in the United Kingdom. A total of 416 responses were collected and the data were analyzed by employing independent sample t-tests to explore gender differences regarding organizational diversity, inclusion, fairness, sexism, psychological safety and affective commitment. The mediating role of psychological safety in the effects of organizational diversity, fairness, inclusion and sexism on staff’s commitment to the organization was evaluated through a series of simple mediation models. Finally, the mediated effect of organizational social psychological factors on affective commitment through psychological safety, moderated by gender was tested.FindingsAs hypothesized, men had higher perceptions of organizational inclusion and diversity and viewed their organization as less sexist. Psychological safety mediated the positive effects of organizational diversity, fairness, inclusion and sexism on staff’s affective commitment to the organization. Organizational diversity and sexism played a bigger part in how women evaluate their organizational environment as safe to take risks and be themselves and consequently on how they commit to the organization. On the other hand, organizational fairness and inclusion seem more closely tied to men’s evaluation of their organization as safe to be themselves and consequently stronger commitment.Originality/valueThe findings shed light on the underlying mechanisms that shape affective commitment, that can lead to more inclusive work environments and contribute to systemic change in the Higher Education context.

Abstract B038: Developing and refining a digital skin cancer intervention among Hispanics

Abstract Background: Over the last 20 years, the incidence of melanoma in Hispanic populations has increased by 20%. The mortality rate of Hispanics is higher compared to non-Hispanic whites. In general, compared to NHW, Hispanics diagnosed with melanoma are younger, have thicker tumors, and have worse survival rates. Skin cancer can be prevented with regular sun protection, and early detection can improve skin cancer outcomes. This study aimed to refine and develop a culturally relevant mobile-based skin cancer prevention intervention for Hispanics through group and individual interviews. Methods: Three focus groups of Hispanics at risk for skin cancer and eight individual interviews with key stakeholders, including healthcare providers and community leaders, were conducted via Zoom. Participants were shown culturally relevant messages developed from previous community interviews and provided further feedback to improve and enhance both the messages and intervention design. The interviews lasted for 60-90 minutes and participants received up to $70 electronic gift cards as an incentive. Results: The focus group (two in English and one in Spanish) participants (n=18), aged 18 to 60 years (M=30). Of these participants, 61.1% were female (n=11), and half reported having an educational level lower than a bachelor's degree. Additionally, more than half of the group indicated a household income below $50,000. Among the eight individual interviews with healthcare providers and community leaders, the participants aged from 18 to 56 and reported being family workers, student group leaders, church leaders, and nurses. Emerging themes from the interviews included: 1) messages and images developed from previous community interviews were relatable and informative; 2) the majority favored visuals with text, and preferred a combination of human and cartoon images; 3) information related to general sun protection and skin examination, such as melanoma and SPF needed to be included, as well as information regarding health literacy such as how to effectively find health information and communicate with a health care provider; 4) some common misconceptions, such as the effectiveness of sunscreen on dark skin and reapplication times, were identified. Additionally, participants expressed hesitancy about undergoing skin examination by oneself and/or a doctor, highlighting the importance of providing more detailed guidance to address misperceptions and enhance adherence. Gender differences in adhering to skin protection measures were evident, with women demonstrating greater commitment despite men's higher melanoma rates and sun exposure, emphasizing the need for targeting of men. Conclusions: Participants expressed satisfaction with the intervention's relevance and informativeness for skin cancer education and promoting preventive behaviors. Insights and new ideas regarding intervention design gained from both the interviews will refine the final intervention, enhancing its cultural relevance and effectiveness in preventing skin cancer among the Hispanic community. Behavioral and Social Science: Community-based Interventions Citation Format: Niu Zhaomeng, Karen Dhami, Yonaira Rivera, Emily Peters, Jemima Baskar, Carolina Lozada, Carolyn Heckman. Developing and refining a digital skin cancer intervention among Hispanics [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr B038.

Sexual consent attitudes mediate gender differences in responsibility attributions for a heterosexual date rape scenario

Sexual consent attitudes mediate gender differences in responsibility attributions for a heterosexual date rape scenario

Impact of agricultural land ownership on child nutrition in rural Sudan: an investigation across gender

Purpose In light of the inequality in access to farming land and the high prevalence of child malnutrition in Sudan, there is a lack of empirical research on the relationship between land ownership and child nutritional status. This study aims to examine the influence of agricultural landholding on the nutritional status of children under the age of five in rural Sudan.Design/methodology/approachThe study utilizes data from Sudan’s 2014 Multiple Indicator Cluster Survey (MICS), covering a sample of 10,753 rural children. The empirical analysis uses the two-stage least squares (2SLS) approach, adopting various estimation methods and model specifications for robustness check and comparison.Findings The results demonstrate that agricultural land has a positive and significant effect on reducing child malnutrition, signifying that children from families with agricultural land are less susceptible to malnutrition in Sudan. When examining the male and female sub-samples separately, the findings indicate a positive influence of land ownership on child malnutrition in the female sub-sample, while no significant impact is observed in the male sub-sample. This indicates a gender disparity in the effects of land ownership on child nutrition, with girls benefiting more from access to agricultural land compared to boys.Originality/value The study has several significant contributions. First, this is the sole study that examines the impact of agricultural land ownership on child malnutrition in Sudan. Second, considering the gender variations in nutritional status, investigating the influence of land ownership on child nutrition across genders addresses a significant gap in the current literature. Finally, the findings resulting from this study can contribute to achieving the United Nations Sustainable Development Goals (SDGs) to be achieved by 2030, precisely focusing on SDG2 Goal 2: Zero hunger and SDG 10: Goal 10: Reduced inequalities.

A pilot study of race, ethnic, gender, and parental education level differences on the Naglieri General Ability Tests: Verbal, Nonverbal, and Quantitative

A pilot study of race, ethnic, gender, and parental education level differences on the Naglieri General Ability Tests: Verbal, Nonverbal, and Quantitative

Rising Obesity-Associated Mortality in Men: Exploration of Gender Disparity from the Global Burden of Disease Study, 1990–2019

Rising Obesity-Associated Mortality in Men: Exploration of Gender Disparity from the Global Burden of Disease Study, 1990–2019

Gender-related measurement invariance on the Self-Reporting Questionnaire (SRQ-20) for global mental distress with older adults in Puerto Rico

BackgroundCommon mental disorders (CMD) vary by age, gender, and culture. This study: (1) examined the factor structure of the 20-item Self Reporting Questionnaire (SRQ-20) and (2) explored gender-related measurement invariance in the SRQ’s performance with older adults in Puerto Rico, a U.S. island territory and associate member of the UN Regional Commissions.MethodsWe merged data from two cross-sectional studies on mental health status and needs of older adults in Puerto Rico (N = 367). The first study was conducted in 2019, two years after Hurricane María devastated the island (N = 154); the second study, in 2021, assessed knowledge, attitudes and practices (KAP) concerning COVID-19 (N = 213). We used chi-square and t-tests to examine gender differences in each SRQ item and assessed internal consistency reliability with Cronbach’s alpha and McDonald’s omega (values > 0.70). We ran two CFA models, then multigroup CFA to test for gender-related measurement invariance. We used weighted least square mean and variance adjusted (WLSMV) estimation to account for the binary response options in the SRQ-20 and Mplus version 8.4 for analyses. There were no missing data for any SRQ-20 items.ResultsThe SRQ-20 had strong internal consistency reliability (α = 0.89; omega = 0.89). Female scores were higher than males scores (t = -2.159, p = .031). Both unidimensional and two-factor models fit the data well. We selected the more parsimonious unidimensional model, which is most widely used in practice. Standardized factor loadings were 0.548 to 0.823 and all were statistically significant (p < .001). We tested gender invariance with the one-factor model. Our findings did not support invariance.ConclusionWe favored the unidimensional model. First, the SRQ-20 was designed to assess global distress. Also, physical symptoms have both somatic and psychological components, so their co-occurrence makes a single-factor model more meaningful. Finally, since older adults experience more physical health problems, instruments that emphasize both types of distress may provide a more accurate measure than those that exclude somatic symptoms. Using the unidimensional model, the SRQ-20 was not invariant, meaning that it performed differently for male and female participants. Future studies of common mental disorders with older adults in Puerto Rico should consider using the SRQ-20 for research and practice and should determine appropriate threshold scores for men and women.

Emotional exhaustion behind the badge: Examining the effects of affective commitment, surface acting, and gender among police personnel

Public service organizations, such as the police, place great value on employee commitment because the public interest is at stake. While previous literature establishes a negative association between affective commitment and emotional exhaustion, the underlying mechanism remains insufficiently explored. Drawing on the perspective of emotional labor, this paper investigates whether surface acting, which refers to the feigning of expected emotions, mediates the impact of affective commitment on emotional exhaustion among police personnel. Furthermore, the study aims to explore whether this mediating effect is influenced by gender. The dataset utilized in this research comprises responses obtained from a survey administered to 465 police officers employed by the Taipei City Police Department. Our findings reveal a significant suppression effect of surface acting in the affective commitment-emotional exhaustion relationship, suggesting that surface acting, as a result of low affective commitment, has a detrimental impact on emotional well-being. Interestingly, the effects of affective commitment and surface acting on emotional exhaustion are stronger in male police officers compared to their female counterparts. In summary, the results of this study contribute to the existing literature and have broader implications for high-stress work environments. The findings provide insights into how organizations can better support the well-being of their employees by promoting commitment and addressing surface acting. Moreover, the study underscores the importance of considering gender differences in understanding the impact of these variables on emotional exhaustion among police personnel.

Comparative Study to Understand Religiosity between Millennials and Gen z in India

The present study tries to quantitatively understand the religiosity among the millennials and Gen Z population in India. As per the current scenario there is a worldwide decrease in religiosity or religious affiliation among millennials and Gen Y. This paper tries to understand this trend among Indian millennials and the Gen Z population. Religion being a sensitive and merely studied concept in the country this research gives a novel and brief outlook of this concept. Forthe research N=140 participants (37 males, 103 females), comprising of Millennials (n=70) and Gen Z (n=70) willingly gave their consent to be a part of the study. The paper analyses the five dimensions of religiosity among participants using The Centrality of Religiosity Scale (Huber &amp; Huber, 2012). In addition to generation change, the study also tries to understand the impact of, gender difference, profession, and, domicile on religiosity. Findings state that religiosity between millennials and gen z do not differ from each other. Key words: Religiosity, millennials, Gen z, Indian population

Classification of musical hallucinations and the characters along with neural-molecular mechanisms of musical hallucinations associated with psychiatric disorders

BACKGROUND Musical hallucinations (MH) involve the false perception of music in the absence of external stimuli which links with different etiologies. The pathomechanisms of MH encompass various conditions. The etiological classification of MH is of particular importance and offers valuable insights to understand MH, and further to develop the effective treatment of MH. Over the recent decades, more MH cases have been reported, revealing newly identified medical and psychiatric causes of MH. Functional imaging studies reveal that MH activates a wide array of brain regions. An up-to-date analysis on MH, especially on MH comorbid psychiatric conditions is warranted. AIM To propose a new classification of MH; to study the age and gender differences of MH in mental disorders; and neuropathology of MH. METHODS Literatures searches were conducted using keywords such as “music hallucination,” “music hallucination and mental illness,” “music hallucination and gender difference,” and “music hallucination and psychiatric disease” in the databases of PubMed, Google Scholar, and Web of Science. MH cases were collected and categorized based on their etiologies. The t -test and ANOVA were employed (P &lt; 0.05) to compare the age differences of MH different etiological groups. Function neuroimaging studies of neural networks regulating MH and their possible molecular mechanisms were discussed. RESULTS Among the 357 yielded publications, 294 MH cases were collected. The average age of MH cases was 67.9 years, with a predominance of females (66.8% females vs 33.2% males). MH was classified into eight groups based on their etiological mechanisms. Statistical analysis of MH cases indicates varying associations with psychiatric diagnoses. CONCLUSION We carried out a more comprehensive review of MH studies. For the first time according to our knowledge, we demonstrated the psychiatric conditions linked and/or associated with MH from statistical, biological and molecular point of view.

Parent-child relationship quality and older parents’ cognitive trajectories

This study assesses the bidirectional link between parent-child relationship quality and older parents’ cognitive trajectories over time, with particular attention to potential variations by parents’ gender. Methods: Using a longitudinal, nationally representative sample of parents aged 50 and older from the Health and Retirement Study 2006–2016, the analysis examines three dimensions of the relationship quality between parents and children—contact, support, and strain—in relation to parents’ cognitive function. Parallel latent growth curve models (LGCMs) estimate how baseline relationship quality relates to subsequent change in parents’ cognition and how parents’ baseline cognitive function relates to subsequent change in relationship quality over time. Results: Higher initial levels of relationship strain with children predicts a faster cognitive decline for older parents. Neither initial contact frequency nor initial relationship support is associated with subsequent change in a parent’s cognition, however, good cognitive function predicts a more rapid increase or a slower decline in contact frequency and relationship support over time. No gender difference was found. Conclusion: The results highlight the importance of the “linked lives” of aging parents and their children as well as the potential for bidirectional associations between cognition and family relationships.

Dental students’ healthy lifestyle behaviors, physical activity levels and social media use: cross sectional study

BackgroundHealthy lifestyle behavior includes appropriate behaviors such as eating habits, physical activity and weight control in order to stay healthy and prevent diseases. The aim of this cross-sectional study is to evaluate healthy lifestyle behaviors, physical activity levels and social media use of dental students.MethodsAn online questionnaire including demographic characteristics, International Physical Activity Questionnaire Short Version (IPAQ-S) and Health Promoting Lifestyle Profile (HPLP) was filed by 420 dental students. The data were evaluated statistically.ResultsThe mean age was 21.6 ± 1.96 years and the majority of the students (71.7%) were living with their families. Obesity and overweight in males and underweight in females were statistically higher. There was no difference between the genders in terms of social media use. The most preferred applications were Instagram (92.7%), YouTube (85%) and Twitter (59.7%). In terms of IPAQ durations and HPLP scores, there was no gender difference. According to the IPAQ classification, while the majority of students (64.3%) were physically low active, 23.1% were physically inactive. As the total HPLP score increased, the total IPAQ score increased.ConclusionIt is concluded that as the university students make up the majority of the young adults, encouraging their health-promoting behaviors is crucial for improving public health.

The moderating function of sexual sanctification on the relation between sexual and relationship satisfaction: A registered report

Past research on sanctification has focused on the direct association between domain sanctification and domain satisfaction. This registered-report study focused on the predicted moderating function of sexual sanctification on the association between sexual and relationship satisfaction. An Internet panel sample of 740 women and 872 men, all married Jewish individuals residing in Israel, assessed the levels of their sexual and marital satisfaction, sexual sanctification, religiousness, and social desirability via an anonymous online questionnaire. As expected, sexual and marital satisfaction were highly correlated. As predicted, sexual sanctification was found to moderate the association between sexual and marital satisfaction for women even after controlling for age, religiousness, and social desirability. However, although the positive association between sexual and relationship satisfaction was predicted to be larger at higher levels of sanctification than at lower levels, the moderation analysis revealed a reverse pattern. In addition, the moderation effect was significant for men only after controlling for religiousness. Post hoc analyses for moderated moderation confirmed significant gender differences in the moderation function of sexual sanctification. The importance of examining gender differences in future sanctification studies and the theoretical implications for the independence of sanctification from religiousness is discussed.

Long-term PTSD prevalence and associated adverse psychological, functional, and economic outcomes: a 12–15 year follow-up of adults with suspected serious injury

ABSTRACT Background: An increasing number of longitudinal studies investigates long-term PTSD, related outcomes and potential gender differences herein. However, a knowledge gap exists when it comes to studies following individual civilian trauma beyond a decade post-trauma. Objective: To investigate the long-term PTSD prevalence, associated adverse psychological, functional and economic outcomes related to (suspected) serious injury of 12–15 years ago in Dutch adults, as well as potential gender differences herein. Method: N = 194 trauma-exposed adults (34% women) admitted to an emergency department following suspected serious injury completed a follow-up assessment 12–15 years (M = 14.30, SD = 1.00) post-trauma. Participants completed assessments of clinician-rated PTSD symptom severity, as well as self-report questionnaires on psychological, functional and economic outcomes. Results: Nine participants (4.8%) fulfilled the DSM-5 diagnostic criteria for PTSD related to the index trauma of 12–15 years ago. Results showed that PTSD symptom severity (CAPS-5) was significantly associated with more severe symptoms of anxiety (HADS) and depression (QIDS), lower well-being (WHO-5) and (health-related) quality of life (WHOQOL; EQ-5D-5L), but not with alcohol use (AUDIT), productivity loss at work (iPCQ) and health care use (iMCQ). No significant gender differences in the long-term PTSD prevalence nor in its related psychological, functional and economic outcomes were found. Conclusions: Our findings underscore the long-term presence of PTSD and associated adverse psychological and functional outcomes in a proportion of adults who experienced (suspected) serious injury over a decade ago. PTSD is already widely recognized for its substantial impact in the aftermath of a trauma. The current study emphasizes the potential long-term consequences of individual civilian trauma, highlighting the importance of accurate screening and prevention for PTSD.

Faculty scholarly productivity in APA-accredited counseling psychology programs: gender and racial disparities

Faculty scholarly productivity in APA-accredited counseling psychology programs: gender and racial disparities

Norms for neuropsychological tests in cognitively healthy French oldest old adults.

Normal aging often leads to cognitive decline, and oldest old people, over 80 years old, have a 15% risk of developing neurodegenerative diseases. Therefore, it is important to have appropriate tools to assess cognitive function in old age. The study aimed to provide new norms for neuropsychological tests used to evaluate the cognitive abilities in people aged 80 years and older in France, focusing on the impact of education and gender differences. 107 healthy participants with an average age of 85.2 years, with no neurological history or major cognitive deficits were included. A comprehensive neuropsychological assessment was performed, covering several cognitive functions such as memory, visuospatial abilities, executive functions, attention, processing speed, and praxis. Individuals with lower levels of education performed poorly on some tests and took longer to complete. Gender differences were observed, with women outperforming men in verbal episodic memory, while men showed better performance in visuoconstructive tasks. The participants showed lower performance in verbal episodic memory compared to norms established in previous French studies. In relation to executive functions, participants were slower to perform complex tasks than participants in previous studies. This study provides cognitive norms specifically adapted to the oldest old population, which differ from established norms for younger aging adults. It highlights the importance of including these norms in future clinical and scientific investigations. The findings underscore the importance of education on cognitive abilities and emphasize the need to consider gender differences when assessing cognitive functions in aging populations.

Workplace happiness in architectural companies in the city of Valencia: a gender comparison

IntroductionHow to make work life increasingly meaningful and ensuring that business actions aim at improving quality of life is a trending topic. Yet, it has not often been studied within architectural firms, that play a crucial role in achieving sustainable development goals, especially those related to equity, equality, and the creation of pleasant work environments. This study aims to identify whether there are gender differences in the perception and levels of workplace happiness of individuals working within architectural companies in Valencia (Spain).MethodsA mixed methodology based on qualitative and quantitative data has been applied with a sample of 201 workers from 60 practices.ResultsParticipants perceive themselves as flourishing and quite happy at work. Yet, there are gender differences in the factors that motivate workplace happiness. While women prioritize the work environment, their colleagues and teams, men point out to career development. Thus, recognition, appreciation, feeling valued and goals and achievements are among the main drivers of men’s workplace happiness. In addition, women tend to experience negative emotions such as anxiety, anger, or sadness more frequently than men. Given these results, architectural companies face a considerable challenge.DiscussionThe research examines the relationship between workplace happiness and social sustainability in architectural firms, highlighting the importance of human capital for competitiveness. To promote sustainability and well-being at work, it is crucial to understand how organizational decisions impact employee well-being and to know the differences in perceptions of workplace happiness between men and women. This analysis may be of interest to the architectural firms object of this research.

The Impact of Frailty and Gender Differences on Hospitalization and Complications in Proximal Femoral Pathological Fractures: A Cross-Sectional Study

Background: Frailty associated with aging increases the risk of falls, disability, and death. The aim of this study is to explore gender-related disparities in the survival outcomes of pathological femoral fractures in older frail patients, while analyzing potential specific prognostic factors. Methods: This study is a retrospective observational analysis conducted at a single medical center. It enrolled all patients aged 65 and above who were admitted to our emergency department between 2016 and 2020 with a diagnosis of pathological femur fracture requiring surgical intervention. The primary study endpoint was evaluating gender-related differences in survival outcomes. The secondary endpoint involves investigating gender-specific prognostic factors through the analysis of clinical and laboratory parameters. Results: The average Charlson Comorbidity Index (CCI) was slightly lower in men, but the difference was not statistically significant (p = 0.53). The Clinical Frailty Scale (CFS) showed similar results, with men and women 5.23 (SD 1.46), also not significant (p = 0.83). An evaluation comparing patients aged 75 years or younger to those older than 75 years found significant differences in health metrics. The average CCI was higher in the over 75 group compared to the under 75 group, with a p-value of 0.001. Similarly, the CFS average was also greater in the over 75 group than in the under 75 group, with a p-value of 0.0001. Complications were more frequent in patients over 75 and those with lower educational qualifications. The evaluation analyzed cardiac patients compared to a control group, revealing that the average age of cardiac patients was 75.22 years, while the control group was younger at 73.98 years (p = 0.5119). The CCI for cardiac patients averaged 6.53, significantly higher than 4.43 for non-cardiac patients (p = 0.0003). Conclusion: Frailty assessment is therefore essential in patients with pathological fracture of the proximal femur and is an important predictor of both gender differences and hospital complications. Enhancing gender analysis in this field is crucial to gather more robust evidence and deeper comprehension of potential sex- and gender-based disparities.

Application of transumbilical single-incision laparoscopy in the treatment of complicated appendicitis in overweight/obese adolescents

ObjectiveTo investigate the clinical efficacy of transumbilical single-incision laparoscopic surgery in the treatment of complicated appendicitis in overweight/obese adolescents.MethodsA retrospective analysis was conducted on the clinical data of 226 adolescent patients with complicated appendicitis who were admitted to our hospital from January 2014 to June 2022. Among them, 102 cases underwent transumbilical single-incision laparoscopic appendectomy as the observation group, and another 124 cases underwent conventional three-port laparoscopic appendectomy as the control group. The surgical time, intraoperative blood loss, duration of incisional pain, postoperative flatus time, length of hospital stay, surgical site infection (SSI), satisfaction with cosmetic result, and occurrence of postoperative complications were compared between the two groups.ResultsBoth groups completed the surgery smoothly, and there were no statistically significant differences in gender, age, BMI, duration of illness, white blood cell count, and preoperative CRP value between the two groups (P > 0.05). There were no statistically significant differences in surgical time and intraoperative blood loss between the two groups (P > 0.05). However, the observation group had shorter hospital stays, shorter duration of incisional pain, shorter postoperative time to flatus, and lower overall postoperative complication rates compared to the control group, with statistically significant differences (P < 0.05). The observation group had higher satisfaction with cosmetic result compared to the control group, with statistically significant differences (P < 0.05). Both groups were followed up for one year postoperatively, and there were no occurrences of residual appendicitis or severe adhesive intestinal obstruction.ConclusionWhen proficiently mastered, the application of transumbilical single-incision laparoscopy in the treatment of complicated appendicitis in overweight/obese adolescents offers advantages such as minimal trauma, rapid recovery, fewer complications, and improved aesthetic outcomes.

Interrelationships among MTHFR gene polymorphisms, MTRR gene polymorphisms, and HBV gene BCP 1762/1764 mutations with disease progression in Chronic hepatitis B virus infection patients

Objective Chronic hepatitis B virus (HBV) infection is a major disease that seriously affects the health of patients. In this paper, the relationship among MTHFR gene polymorphism, MTRR gene polymorphism and 1762/1764 mutation in the BCP region of HBV gene with disease progression in chronic HBV patients was studied. Methods A total of 144 chronic HBV infection patients from January 2021 to June 2022 in the Third People’s Hospital of Zigong City, were included as the study subjects. These patients were divided into hepatitis B primary liver cancer patients group (PLC) in 51 cases, Non-primary liver cancer patients group (Non-PLC) in 93 cases, Non-PLC is also divided into chronic hepatitis B virus carriers (CHC) in 49 cases, hepatitis B Live cirrhosis(LC) in 44 cases. MTHFR (C677T), MTRR (A66G) and MTHFR (A1298C) genes polymorphisms were detected by PCR-dissolution curve. The level of HBV-DNA was quantified by real-time PCR, and the 1762/1764 mutation site in the BCP region of the HBV gene were detected by ARMS-PCR. Data were statistically analyzed using the SPSS statistical software. Results The proportion of HBV mutations in BCP region 1762/1764 in PLC group was 82.4%, which was higher than that in LC group (63.6%) and CHC group (51.0%), and the differences were statistically significant (p < 0.05). There were no significant differences in the distribution of MTHFR C677T, MTHFR A1298C and MTRR A66G polymorphisms among CHC, LC and PLC (p > 0.05). The polymorphism distribution of MTHFR C677T, MTRR A66G and MTHFR A1298C genes in patients with chronic hepatitis B virus infection at different stages (CHC, LC and PLC) showed no gender or age differences between and within groups (p > 0.05). Among the patients with MTHFR 677CT + TT, MTRR 66AG + GG and MTHFR 1298AA genotype, the proportion of HBV mutation in BCP region 1762/1764 in PLC group was higher than that in CHC group and LC group, and the differences were statistically significant (p < 0.05). Folate levels in the PLC group were lower than those in the non-PLC group (CHC and LC patients), and the difference was statistically significant compared with the CHC group (p < 0.05). In different MTHFR C677T and MTRR A66G genotypes, the serum GGT activity were statistically significant between mutant PLC and mutant Non-PLC (p < 0.05). Conclusion MTHFR C677T, MTRR A66G and MTHFR A1298C gene polymorphisms distribution have no gender and age differences in chronic hepatitis B virus infection patients. The mutation of HBV gene BCP region 1762/1764 may be associated with the occurrence and development of liver cancer in patients with chronic HBV infection. Single difference of MTHFR C677T, MTHFR A1298C and MTRR A66G gene polymorphisms may have little effect on the disease progression in patients with chronic HBV infection. MTHFR 677CT + TT, MTRR 66AG + GG and MTHFR 1298AA genotype combined with HBV gene BCP region 1762/1764 mutation may be closely related to the occurrence and development of hepatitis B liver cancer.