ABSTRACT This study examines sexual humour in some Ghanaian and Nigerian YouTube comedy skits through the theoretical lens of social semiotics. It focuses on two YouTubers, Jeffrey Nortey from Ghana and Viper the Wiper from Nigeria, purposively sampled for their extensive use of sexual humour. Analysis reveals that they employ intertextuality, exaggeration, and dramatic irony as their key communicative strategies. Intertextuality draws on folk knowledge, the Bible, social, and religious issues. Exaggeration is used to depict actions that are humanly impossible, while dramatic irony introduces unexpected twists. The effectiveness of these strategies is evident from the numerous views and comments their skits receive, highlighting their successful engagement with the taboo topic of sex. However, the study also notes the potential negative impact of some sexual jokes, which may reinforce harmful stereotypes about men and women. It underscores the importance of responsibly portraying human sexuality in humour, advocating the avoidance of perpetuating damaging societal norms through comedic narratives.