The coronavirus that causes severe acute respiratory syndrome (SARS-CoV-2) is a positive sense single stranded RNA (ssRNA) virus that first appeared in China and has spread throughout the world since late 2019. The SARS-CoV-2 virus causes a mild to severe respiratory infection that affects not just the lungs but also pancreas and other endocrine glands, as well as responsible for ischemic stroke and sexual dysfunctions. Serum pro-calcitonin (PCT) levels have been linked to the severity of coronavirus disease (COVID-19) in several investigations. According to our studies, high PCT levels are linked to a greater risk of severe COVID-19 infection in patients, as well as its involvement and role in a COVID-19 infected cancer survivor. This is the first study we are aware of from India that shows COVID-19 infected people should have regular PCT screening may help clinicians to plan intensive care unit (ICU) placement and detect any recurrence of past illness if any.