SESSION TITLE: Analyzing What We Do in the ICUSESSION TYPE: Rapid Fire Original InvPRESENTED ON: 10/17/2022 12:15 pm - 1:15 pmPURPOSE: Limbs pneumatic compression during cardiopulmonary resuscitation (CPR) for cardiac arrest patient were rarely reported. We aimed to evaluate the impact of this therapy on the patient with cardiac arrest.METHODS: It was a prospective and controlled study, a total of 46 elderly(74.8±5.3 yrs) cardiac arrest patients were included and randomized to “CPR group “(n=23) and “CPR + Pneumatic Compression group” (n=23). Each patient in CPR group accepted standard CPR. In addition to standard CPR, all subjects in “Pneumatic Compression group” received intermittent pneumatic compression(IPC) by Air Compression Therapy System, which digital six-tiered rippling full-body pressure (0.45~0.6kg/cm2) and 1 minute interval every 3 minutes.RESULTS: Patients with standard CPR had higher incidence of acute kidney injury(AKI)than in “CPR + Pneumatic Compression group” (52.2% vs. 21.7%,p=0.032).Besides, the lower occurrence of hypoxic ischemic encephalopathy(HIE) was observed in Pneumatic Compression group(Figure 1) . Compared to standard CPR group, significant improvements of cardiac output(CO) and survival of patient were observed in Pneumatic Compression group(Figure 2). The average blood velocity of femoral vein during intermittent period was 4.2±1.7cm/s and 3.8±1.2cm/s in “CPR group” and “CPR + Pneumatic Compression group” respectively (p=0.361).CONCLUSIONS: Intermittent limbs pneumatic compression during cardiopulmonary resuscitation(CPR) maybe improve survival of cardiac arrest.CLINICAL IMPLICATIONS: Limbs pneumatic compression maybe could improve clinical outcomes of cardiopulmonary resuscitation by enhancing the blood flow of the crucial organs(e.g. brain) ,it seems to be an optimizing strategy for CPR, and which need further study.DISCLOSURES: No relevant relationships by Boxue Han SESSION TITLE: Analyzing What We Do in the ICU SESSION TYPE: Rapid Fire Original Inv PRESENTED ON: 10/17/2022 12:15 pm - 1:15 pm PURPOSE: Limbs pneumatic compression during cardiopulmonary resuscitation (CPR) for cardiac arrest patient were rarely reported. We aimed to evaluate the impact of this therapy on the patient with cardiac arrest. METHODS: It was a prospective and controlled study, a total of 46 elderly(74.8±5.3 yrs) cardiac arrest patients were included and randomized to “CPR group “(n=23) and “CPR + Pneumatic Compression group” (n=23). Each patient in CPR group accepted standard CPR. In addition to standard CPR, all subjects in “Pneumatic Compression group” received intermittent pneumatic compression(IPC) by Air Compression Therapy System, which digital six-tiered rippling full-body pressure (0.45~0.6kg/cm2) and 1 minute interval every 3 minutes. RESULTS: Patients with standard CPR had higher incidence of acute kidney injury(AKI)than in “CPR + Pneumatic Compression group” (52.2% vs. 21.7%,p=0.032).Besides, the lower occurrence of hypoxic ischemic encephalopathy(HIE) was observed in Pneumatic Compression group(Figure 1) . Compared to standard CPR group, significant improvements of cardiac output(CO) and survival of patient were observed in Pneumatic Compression group(Figure 2). The average blood velocity of femoral vein during intermittent period was 4.2±1.7cm/s and 3.8±1.2cm/s in “CPR group” and “CPR + Pneumatic Compression group” respectively (p=0.361). CONCLUSIONS: Intermittent limbs pneumatic compression during cardiopulmonary resuscitation(CPR) maybe improve survival of cardiac arrest. CLINICAL IMPLICATIONS: Limbs pneumatic compression maybe could improve clinical outcomes of cardiopulmonary resuscitation by enhancing the blood flow of the crucial organs(e.g. brain) ,it seems to be an optimizing strategy for CPR, and which need further study. DISCLOSURES: No relevant relationships by Boxue Han