Pickering high internal phase emulsions (HIPEs) show promise for solid fat replacement and nutrient delivery, but the availability of safe and easily accessible food-borne particulate emulsifiers is a bottleneck limiting their practical application. In this study, the feasibility of using sesame meal as an emulsifier for the construction of sunflower oil-based Pickering HIPEs was evaluated. These HIPEs were then characterized in terms of their microstructural and mechanical properties, and utilized as a substitute for butter in cake production. Results showed that sesame meal is rich in protein, and has a particle size (median diameter, 46.40 ± 0.83 μm), and wettability that makes it suitable for use as an emulsifier. It stabilized O/W type Pickering HIPEs formulated with sunflower oil with a volume fraction of up to 80 %. The mechanical properties of these Pickering HIPEs were positively correlated with the concentration of sesame meal. Sunflower oil-based HIPEs prepared from sesame meal can partially replace butter for cake preparation when φ = 80 % and c = 9.0 %, and enhance the internal pore structure of cake when butter substitution (Wb) ≤ 30 %. This provides a new way to use sesame meal and new type of food-grade Pickering HIPEs.