Serum Magnesium Levels In Women Research Articles

SERUM MAGNESIUM LEVELS IN WOMEN’S WHO ATTAINED MENOPAUSE NATURALLY AND SURGICALLY: ANALYTICAL CROSS SECTIONAL STUDY

Aim: Serum magnesium levels in women’s who attained menopause naturally and surgically.
 Methods: The present analytical cross sectional study was conducted on patients (out patients and in patients) in Department of Obstetrics and Gynecology, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar, India. Group 1 (N=60): Women who had undergone hysterectomy with bilateral salphingoophorectomy at least 6 month ago. Group 2 (N=60): Women who have attained natural menopause at least 1 year ago. Serum magnesium was estimated by magnesium by Xylidyl blue colorimetric assay.
 Results: In the present study maximum number of the patients 26 (43.3%) were in the age group of 46-50 years for the post surgical menopausal group and in the natural menopausal group maximum number of the patients were in the age group of 51-55 years 23 (38.3%). Maximum numbers of patients are multiparous in both groups. Hypomagnesemia was observed in 29 (48.3%) natural menopausal group and 17 (28.3%) were postsurgical menopausal. Hypermagnesemia was observed in 1 (1.7%) postsurgical menopausal group.
 Conclusions: The prevalence of osteoporosis is very high in this part of India. Both natural and post- surgical menopausal women have lower levels of serum magnesium.
 Keywords: Osteoporosis, Serum Magnesium

Evaluation of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM), a glucose intolerance state during pregnancy is a strong predictor of post-partum prediabetes and one of the risk factors for overt type 2 diabetes (T2DM). Magnesium a trace element influences the cell's response to insulin and decreased levels of magnesium are related to insulin resistance and T2DM. Several literatures are available on effects of magnesium on T2DM with dearth in research regarding the impact of magnesium on GDM. In this backdrop our present study was designed to determine serum magnesium level in women with and without GDM. A cross sectional case control study was conducted at Adichunchanagiri Institute of Medical Sciences and Hospital. The total numbers of subjects were 90, divided into two groups, Group I- 45 pregnant women with Gestational diabetes mellitus as cases, Group II- 45 pregnant women without GDM as controls. Blood samples were drawn under aseptic precautions from study subjects. Serum magnesium levels were determined by commercially available Calmagite kit method. The mean serum magnesium level was found to be significantly lower in group I subjects when compared to group II subjects with the p value <0.0001. To conclude, results of our study demonstrated that hypomagnesaemia an underlying factor in determining disrupted glucose metabolism in pregnant women and magnesium supplementation might help patients with GDM to control their metabolic profile and pregnancy outcomes.

Maternal Magnesium Level Effect on Preterm Labor Treatment

Objectives: This study intended to compare the serum magnesium level in women with preterm labor, with its level in women with normal pregnancy of the same age, and assess the relationship between serum magnesium level and response to magnesium sulfate (MgSO4). Materials and Methods: Forty women aged 18-40, with gestational age of 26-32 weeks and signs of preterm labor, and 40 women in similar age and gestational age with normal pregnancy were included in this study. Case group received betamethasone 12 mg in 2 separate doses with 24-hour interval. MgSO4 was administrated (in dose of 4 mg), and continued by 2 mg/h. Once the tocolytic therapy goal was achieved, the administration of MgSO4 continued for an additional 12-hour. Results: The mean age, gestational age, gravidity, parity, number of live born children, number of dead children, miscarriage, and molar pregnancy were similar in 2 groups. The mean of serum magnesium level showed a significant difference between 2 groups. In the case group, 27 patients showed positive therapeutic response to MgSO4; the difference between the mean of serum magnesium level in these 27 patients and the other 13 patients who did not respond well was significant. The serum magnesium level < 1.85 mg/dL as a cut-off point had 85 sensitivity and 78 specificity with CI = 0.75-0.97 in predicting response to MgSO4 in the case group. Conclusion: Serum magnesium level can be used as a predictive tool for preterm labor. It can help in preterm labor in selecting patients who benefit from MgSO4 as a tocolytic agent. Magnesium supplementation may be helpful in patients with decreased serum magnesium level to prevent preterm labor. © 2018 The Author (s).

Serum Magnesium Levels in Women with Breast Cancer in Benin City, Nigeria

Aim: The aim of this study was to compare the serum magnesium levels of patients with breast cancer and apparently healthy people without the disease. Study Design: This is a cross-sectional prospective study.

Low Serum Magnesium in Preterm Labour

This study was designed to compare serum magnesium levelin women with preterm labour and with those who were interm labour.A case-control study was carried out in the department ofObstetrics and Gynaecology, Bangabandhu Sheikh MujibMedical University (BSMMU), Dhaka from July 2005 toJune 2007, to evaluate serum magnesium level in womenwith preterm labour (28-36 weeks) and compare them withthose who were in term labour (37-40 weeks). The totalnumber of cases was 160, of which 80 were cases and similarnumber were control.The study subjects were selected from inpatient departmentof Obstetrics and Gynaecology, BSMMU and Mother andChild Health Training Institute (MCHTI), Dhaka.Serum magnesium level was measured by taking 5 ml of bloodfrom women with term (control) and preterm labour (case).The basic characteristics, like age, parity and socioeconomicstatus did not show statistically any significant differencebetween control arid case groups, but showed significantdifference only in the body mass index between the twogroups. Mean (±SD) BMI in control and case groups were24.88±1.42 and 23.12±2.36 kg/m2 respectively.Mean (±SD) gestational age were 38.95±0.89 and33.03±1.83 weeks, respectively in control and case groups.The mean (±SD) serum magnesium levels were 2.02±0.20(range 1.70-2.4) and 1.65±0.19 (range 1.30-2.00) mg/dl,respectively, in control and case groups. ‘The difference washighly significant (p&lt;0.001).DOI: 10.3329/jbcps.v28i2.5368J Bangladesh Coll Phys Surg 2010; 28: 69-72