A new approach, named the sequential LQG solution for nonlinear and nonstationary systems tracking problem, has been proposed in the article. Proposed method for tracking of a desired reference trajectory uses a state space model of the multivariable nonlinear/nonstationary system. The method involves three steps. The first step is the design of nominal trajectory using the predictive control technique. The second step is the sequential linearization of the nonlinear system around the fixed operating points, chosen in accordance to the plant dynamics changes. The third step involves the choice of the weighting matrices in the classical LQG controller design for the sequence of linearized models. The feasibility of the proposed method has been demonstrated through its application to the control of aircraft, represented by the six-degree-of-freedom model around the prespecified nominal trajectory.