Sequential Form Research Articles

Serine protease RAYM_01812 (SspA) inhibits complement-mediated killing and monocyte chemotaxis and contributes to virulence of Riemerella anatipestifer in ducks

ABSTRACT Riemerella anatipestifer (RA) is a significant poultry pathogen causing acute septicemia and inflammation. The function of protease RAYM_01812, responsible for gelatin degradation, is unexplored in RA pathogenesis. To elucidate its role, we generated a deletion mutant ΔRAYM_01812 (ΔRAYM) and complementary CΔRAYM_01812 (CΔRAYM) strain and revealed the protease’s role in extracellular gelatinase activity. By expressing full-length 76 kDa RAYM_01812 protein without signal peptide as well as seven partial structural domains fragments, we evidence that the N-terminal propeptide acts as an enzymatic activity inhibitor and it gets cleaved at A112. Also, we show that the β-fold sheet domain is necessary for enhancing the enzymatic protease activity. Sequential auto-proteolysis forms a stable 40 kDa enzyme. Then, testing the strains in duck sera indicated that the absence or presence of RAYM_01812 results in reduced or enhanced bacterial survival, respectively. Furthermore, we found that the protease is able to cleave IgY antibodies as well as the complement factors C3a and C5a, that the protease reduces C3a- or C5a-mediated monocyte chemotaxis, and results in enhanced membrane attack complex (MAC) formation on the surface of ΔRAYM compared to CΔRAYM. This suggests that RAYM_01812 plays a crucial role in protecting against the serum complement-mediated bactericidal effect through inhibiting MAC formation and monocyte chemotaxis. Animal infection assays showed a 1090-fold reduced virulence of ΔRAYM compared to RA-YM, evidenced by decreased tissue loading and weaker histopathological changes. In conclusion, RAYM_01812 acts as a vital virulence factor, enabling host innate immune defence escape through complement killing evasion and monocyte chemotaxis inhibition.

A Note on Fractional Third-Order Partial Differential Equations and the Generalized Laplace Transform Decomposition Method

This paper establishes a unique approach known as the multi-generalized Laplace transform decomposition method (MGLTDM) to solve linear and nonlinear dispersive KdV-type equations. This method combines the multi-generalized Laplace transform (MGLT) with the decomposition method (DM), and offers a strong procedure for handling complicated equations. To verify the applicability and validity of this method, some ideal problems of dispersive KDV-type equations are discussed and the outcoming approximate solutions are stated in sequential form. The results show that the MGLTDM is a dependable and powerful technique to deal with physical problems in diverse implementations.

Sentinel Shield: Leveraging ConvLSTM and Elephant Herd Optimization for Advanced Network Intrusion Detection

Given the escalating intricacy of network environments and the rising level of sophistication in cyber threats, there is an urgent requirement for resilient and effective network intrusion detection systems (NIDS). This document presents an innovative NIDS approach that utilizes Convolutional Long Short-Term Memory (ConvLSTM) networks and Elephant Herd Optimization (EHO) to achieve precise and timely intrusion detection. Our proposed model combines the strengths of ConvLSTM, which can effectively capture spatiotemporal dependencies in network traffic data, and EHO, which allow the model to focus on relevant information while filtering out noise. To achieve this, we first preprocess network traffic data into sequential form and use ConvLSTM layers to learn both spatial and temporal features. Subsequently, we introduce Elephant Herd Optimization that dynamically assigns different weights to different parts of the input data, emphasizing the regions most likely to contain malicious activity. To evaluate the effectiveness of our approach, we conducted extensive experiments on publicly available network intrusion CICIDS2017 Dataset. The experimental results demonstrate the efficacy of the proposed approach (Accuracy = 99.98%), underscoring its potential to revolutionize modern network intrusion detection and proactively safeguard digital assets.

ORGANIC FARMING AND MARKETING CHALLENGES: A CASE STUDY OF HARYANA

The growing issues of health among people and increasing awareness for organic products has directed number of people towards organic consumption. This also led the number of opportunities for farmers to produce organic food. Along with the emerging opportunities, farmers are also facing challenges, thus this study aims to explore the limitations and challenges faced by farmers to switch over organic productions. The sample size for this study comprised 100 farmers from various districts in Haryana, which includes both organic as well as conventional producers. For this study, sequential form of mixed method is used, that is quantitative as well as qualitative. The major findings of qualitative analysis revealed six major market challenges namely, less production, shortage of warehousing facility, lack of government support especially in form of subsidy and promotion, inadequate demand of crops, market price issues and high cost of transportation. This study is to understand market challenges for organic farmers in a developing country like India. The findings of this study will contribute to various stakeholders at policy level to build better strategies to successful promotion of organic farming. This will definitely contribute in fulfilling healthy consumption in India as well as reaching the goals of sustainable development goals.

Моделювання акустичного поля на основі дисперсії звуку при відбитті трасуючих хвиль на відкритих майданчиках

A method of numerical modeling of acoustic fields in open areas with the possibility of parallelization of calculations is proposed. This method is part of a developed software solution that allows you to perform physical field modeling in various subject areas, being scalable in the sense of using an arbitrary set of parallel calculators. The use of existing modeling systems is associated with great difficulties in solving complex problems with a high degree of detail of the simulated object. Greater accuracy implies a high degree of discretization, a greater number of elementary model calculations performed. Parallel and distributed computing systems have a much better ratio of accuracy-approximation and time and cost costs compared to single-processor systems. Modern general purpose modeling systems use a simplified ray model of sound propagation, which neglects diffractional and interference effects, which are often critical in industrial acoustics. The article proposed a method based on the approximation of the principle of superposition of sound fields. It is accurate, while the linearity of the equations of acoustics is relevant. The basis is the Rayleigh integral and the approximation of reflective surfaces by flat point radiators. A parallel form of such a method is presented, as well as an analysis of its properties, both in sequential and parallel forms.

Potential Supervision Consultant Contract Disputes Due to Extension of Contractor Time in DKI Jakarta Regional Government Project Based on Fidic White Book

DKI Jakarta is a province in Indonesia that has the most significant regional budget (APBD). This has led to numerous infrastructure development projects funded by the regional budget in Jakarta. Most projects in Jakarta follow a traditional document tendering process, where procurement starts with the engagement of planning consultants to design a project. After the planning documents are completed, contractor and supervision consultant services are procured concurrently. This research aims to identify the factors that result in non-extension and non-payment of supervising consultants and to determine the potential dominant disputes in supervising consultant contracts due to contractor time extension addendums, particularly in projects within the regional government environment of DKI Jakarta. The aim is to minimize the impact of such issues in the future. This research is a combined study with a sequential form. The population of this research consists of building construction projects in the province of DKI Jakarta. The sample for this research is a sports arena construction project. The respondents in this study are the project owners and the supervising consultants associated with the research project. The data will be processed using a rating evaluation method, allowing for the relative comparison of the predetermined variable categories with each other. The provisions should be based on fairness between the contracting parties. The research findings indicate that supervising consultants are entitled to time extensions and additional fees for supervision during the extended period, due to the contractor's extension of the physical implementation time based on technical considerations. The feasibility of the extension proposal is assessed through research, and the results are documented in an addendum to the contract.

Patients’ Problem Presentation in China’s Primary Care

ABSTRACT Identifying patients’ reasons for visiting is the central task at medical openings, the structure of which has been well studied in Western primary care, but much under-researched in China’s mainland. Drawing on conversation analysis of 91 audio-recorded primary care consultations in China, this study explores interactional features of patients’ problem presentation at medical openings in terms of sequential positions, forms, and contextual contingencies, which has implications for the model of medical service encounters in Chinese primary care openings. Although problem description is commonly solicited by doctors across cultures, Chinese patients’ problem presentation often takes forms other than problem description. Nearly two thirds of problem presentation in our data are designed as a request-making action (57/91 cases), being more often self-initiated than solicited. This blurs the boundary between medical visits for new and non-new problems. The analysis of Chinese patients’ problem presentation points to a high degree of patient agency in primary care in China, suggesting a strong orientation to the “provider-consumer” (vs. “professional-client”) model of service encounters in the opening structure of doctor-patient interaction.

Some novel Kulisch-Miranker type inclusions for a generalized class of Godunova-Levin stochastic processes

<abstract><p>Mathematical inequalities supporting interval-valued stochastic processes are rarely addressed. Recently, Afzal et al. introduced the notion of $ \mathtt{h} $-Godunova-Levin stochastic processes and developed Hermite-Hadamard and Jensen type inequalities in the setting of interval-valued functions. This note introduces a more generalized class of Godunova-Levin stochastic process that unifies several previously published results through the use of Kulisch-Miranker type order relations that are rarely discussed in relation to stochastic processes. Further, it is the first time that fractional version of Hermite-Hadamard inequality has been developed by using interval-valued stochastic processes in conjunction with a classical operator. Moreover, we give new modified forms for Ostrowski type results and present a new way to treat Jensen type inclusions under interval stochastic processes by using a discrete sequential form. We end with an open problem regarding Milne type results and discuss the importance of different types of order relations related to inequality terms in interval-valued settings.</p></abstract>

Processes

There is a big gap between the abstraction of an idea and its concrete implementation. This gap is filled with processes that imply the taking of actions to help achieve a tangible result, and there is a myriad of ways these actions can follow through. Photographic and filmic methodologies shape work through the processes of doing informed by gestures in the photographic and filmic operations on site and in the later editing phase1 by which an understanding is changed into a story, an idea in a final visual and/or sequential form.
 The need for good ideas due to the growing challenges presented by climate changes, imposes serious thinking around actual ways of doing relevant contributions to help ‘heal a broken world’. Photographic and filmic work processes can support that purpose embedding specific site experience methodologies open to the passage of time and the changes it encompasses associated with the landscape we have inherited. Exploring a place or a landscape and working with what is found through movement: walking, driving, flying, the editing of footage, the study of photographs, films, or selected material, reveal changes to specific landscapes and possible readings, interpretations, and understandings of those changes. Such actions and processes have a long tradition in artistic practices transecting land art, landscape architecture and environmental studies.2
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Sequence representation as an early step in the evolution of language.

Human language is unique in its compositional, open-ended, and sequential form, and its evolution is often solely explained by advantages of communication. However, it has proven challenging to identify an evolutionary trajectory from a world without language to a world with language, especially while at the same time explaining why such an advantageous phenomenon has not evolved in other animals. Decoding sequential information is necessary for language, making domain-general sequence representation a tentative basic requirement for the evolution of language and other uniquely human phenomena. Here, using formal evolutionary analyses of the utility of sequence representation we show that sequence representation is exceedingly costly and that current memory systems found in animals may prevent abilities necessary for language to emerge. For sequence representation to evolve, flexibility allowing for ignoring irrelevant information is necessary. Furthermore, an abundance of useful sequential information and extensive learning opportunities are required, two conditions that were likely fulfilled early in human evolution. Our results provide a novel, logically plausible trajectory for the evolution of uniquely human cognition and language, and support the hypothesis that human culture is rooted in sequential representational and processing abilities.

Proposal for sequential Stern–Gerlach experiment with programmable quantum processors

The historical significance of the Stern–Gerlach (SG) experiment lies in its provision of the initial evidence for space quantization. Over time, its sequential form has evolved into an elegant paradigm that effectively illustrates the fundamental principles of quantum theory. To date, the practical implementation of the sequential SG experiment has not been fully achieved. In this study, we demonstrate the capability of programmable quantum processors to simulate the sequential SG experiment. The specific parametric shallow quantum circuits, which are suitable for the limitations of current noisy quantum hardware, are given to replicate the functionality of SG devices with the ability to perform measurements in different directions. Surprisingly, it has been demonstrated that Wigner’s SG interferometer can be readily implemented in our sequential quantum circuit. With the utilization of the identical circuits, it is also feasible to implement Wheeler’s delayed-choice experiment. We propose the utilization of cross-shaped programmable quantum processors to showcase sequential experiments, and the simulation results demonstrate a strong alignment with theoretical predictions. With the rapid advancement of cloud-based quantum computing, such as BAQIS Quafu, it is our belief that the proposed solution is well-suited for deployment on the cloud, allowing for public accessibility. Our findings not only expand the potential applications of quantum computers, but also contribute to a deeper comprehension of the fundamental principles underlying quantum theory.

SFT-Box: An Online Approach for Minimizing the Embedding Cost of Multiple Hybrid SFCs

In Network Function Virtualization (NFV), a series of Virtual Network Functions (VNFs) organized in a specific order (called Service Function Chain, SFC) could offer an end-to-end network service for a network flow. Recently, with the new results of the exploration of VNF parallelism, hybrid SFC (SFC contains parallel VNFs) is proposed to reduce the SFC execution delay. However, it remains challenging and open to optimally embed multiple hybrid SFCs into the network. In this paper, we target at the optimal embedding problem of multiple hybrid SFCs with the purpose of minimizing the cost in an online scenario. Specifically, we propose SFT-Box, an online approach that can respond to hybrid SFC embedding requests in real-time. SFT-Box is designed to i) transform SFCs from the traditional sequential form to a standardized hierarchical Service Function Tree (SFT) form, ii) calculate and store the low-cost sub-solutions of embedding common SFTs, and iii) provide prompt solution response based on stored sub-solutions. To the best of our knowledge, this is the first work to address the online optimal embedding problem of multiple hybrid SFCs. With extensive evaluations, we demonstrate that, compared with the benchmark methods, SFT-Box can achieve up to <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$30\%$</tex-math> </inline-formula> cost-saving and at least <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$22\times$</tex-math> </inline-formula> latency reduction in enabling real-time response.

Numerical evaluations on the effects of different factors on thermo- mechanical behaviour of an energy pile group

Energy pile is a kind of economical and efficient underground energy structure. Obtaining the effects of different factors on the performance of energy pile help to improve the working efficiency of the energy pile. However, the thermo-mechanical behaviour of energy pile groups are more complex than that in single energy pile due to the mutual interference of energy pile groups. In this paper, the energy pile group with the layout of 3 × 3 was simulated by a 3-D numerical model. The influences of soil type, pile spacing, pile material performance and pile arrangement form on the thermo-mechanical behaviour of the energy pile group were investigated. The results show that increasing pile spacing can not only improve the thermal performance of energy pile group but also reduce the pile displacement, but it will lead to the increase of pile axial force because of the weakening of pile group effect. The thermal performance of energy pile group is the highest under the rock-soil condition, followed by sand and clay. However, the pile displacement is the largest when the soil type is sand, followed by clay, and the rock-soil is the smallest, and the influence of soil type on pile axial force is just opposite to pile displacement. At the same time, the increase of thermal conductivity of pile material benefits to heat transfer performance of energy pile group, but it also aggravates the heat accumulation and results in a larger top displacement and axial force of pile. As for concrete compression modulus, increasing the concrete compression modulus can increase the axial force of pile, but the change of concrete compression modulus has no effect on the pile displacement. In terms of layout of energy pile group, the per unit soil volume heat exchange rate of energy pile group in the cross arrangement form is larger than that in sequential arrangement form. However, the variation range of soil temperature in the cross arrangement form is larger than that in the sequential arrangement form, thus increasing pile displacement and reducing pile axial force.

Potensi Sengketa Kontrak Konsultan Pengawas Akibat Perpanjangan Waktu Kontraktor pada Proyek Pemerintah Daerah Dki Jakarta Berdasarkan Fidic White Book

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Fast slope algorithm with the use of vectorization and parallelization for multicore architectures

The slope calculation algorithm is one of the most widely used geospatial algorithms employing the 3x3 moving window technique (along with calculation of aspect, curvature and flow direction). This work presents an approach consisting of transforming a slope algorithm from a sequential form into a version that can exploit vector and parallel traits of multicore architectures with vector instructions. This approach allows us to take advantage of the potential of the modern multicore processors. The basic idea for optimizing the 3x3 moving window computation is to split the equation used to calculate the result into parts that operate on data that are known to exist in adjacent memory locations. The research was conducted on two multicore architectures without the change in the code — the older architecture was Sandy Bridge and the newer one was Haswell (with more cores). The efficiency of the developed slope algorithm was verified in practice with the use of DEM files of the same resolution but of different sizes. We showed through the numerical experiments that our approach gives better time performance than the original algorithm (and other tools) — and with no loss of accuracy.

Logical Relations according to De Beauvoir and Their Impact on Achieving Textual Coherence (Usul Al-Kafi as a Model)

Semantic relationships are the concepts carried by the syntactic structures of the text and are an important axis of textual relationships. The continuity and coherence of the text presupposes the existence of this type of relationship between the parts of the text and determines its appearance and unity. Each language has syntactic systems that work towards the text to control them to give different meanings. They work to gather the ends of the text in a sequential form, and the difference between semantic relationships is due to the difference in syntactic structures in the text, and some surface structures work to highlight meanings in the form of semantic relationships that reveal the meaning of the text and the main purpose for which these relationships were established, and relationships may differ in terms of some of them relying on clear linguistic links in the apparent text, as they are sometimes external relationships that the recipient imposes on the text, not the text itself, and are a result of textual phenomena such as advancement, delay, and pronoun references. There are relationships that become clear through conjunctions that connect sentences, or through referential elements. Relationships represent links for concepts that work to continue meanings in the fabric of the text through exchange between sender and recipient. Every text that is issued from producer to recipient is not free from these relationships, and these relationships take place within an organizational framework governed by the intention of the speaker and the other party, readers. In Kafi's conversations, we find that Al-Maqam relies on the semantic dimension in the process of coherence of texts.

Institutional Innovation in University-based Experimental Spaces: the Case of Oulu Game Lab

Abstract This article explores preconditions and developmental dynamics of institutional innovation in higher education organizations as an outcome of a collaborative educational initiative – a university-based experimental space. Such collaborative learning configurations are often designed to stimulate local economic development after a downturn in regional industrial landscapes. The experimental space studied here had a twofold mission: providing re-skilling and re-education opportunities for unemployed ICT professionals and equipping them with business and employment bonds with regional game industry companies. To imbue a static outcome of institutional innovation with dynamic features, and to further develop the concept of Triple Helix spaces, we incorporated three sequential forms of institutional work in our analysis: boundary work, distancing work, and anchoring work.

Research on Kinematic and Static Filtering of the ESKF Based on INS/GNSS/UWB.

With the widespread development of multiple sensors for UGVs, the multi-source fusion-navigation system, which overcomes the limitations of the use of a single sensor, is becoming increasingly important in the field of autonomous navigation for UGVs. Because federated filtering is not independent between the filter-output quantities, owing to the use of the same state equation in each of the local sensors, a new kinematic and static multi-source fusion-filtering algorithm based on the error-state Kalman filter (ESKF) is proposed in this paper for the positioning-state estimation of UGVs. The algorithm is based on INS/GNSS/UWB multi-source sensors, and the ESKF replaces the traditional Kalman filter in kinematic and static filtering. After constructing the kinematic EKSF based on GNSS/INS and the static ESKF based on UWB/INS, the error-state vector solved by the kinematic ESKF was injected and set to zero. On this basis, the kinematic ESKF filter solution was used as the state vector of the static ESKF for the rest of the static filtering in a sequential form. Finally, the last static ESKF filtering solution was used as the integral filtering solution. Through mathematical simulations and comparative experiments, it is demonstrated that the proposed method converges quickly, and the positioning accuracy of the method was improved by 21.98% and 13.03% compared to the loosely coupled GNSS/INS and the loosely coupled UWB/INS navigation methods, respectively. Furthermore, as shown by the error-variation curves, the main performance of the proposed fusion-filtering method was largely influenced by the accuracy and robustness of the sensors in the kinematic ESKF. Furthermore, the algorithm proposed in this paper demonstrated good generalizability, plug-and-play, and robustness through comparative analysis experiments.

Effects of Computer-Animation among NCE Students’ of Different Ability Levels in Biology Concepts in Bauchi State, Nigeria

Computer-animation is the use of computer device to create an illusion of moving images in sequential form. Computer-animations, when effectively used in teaching abstract and complex concepts especially in Biology, better performance could be granted. This study investigated the effects of computer-animation on NCE students with different ability levels in Biology concepts in Bauchi State, Nigeria. The objective of the study was to determine the effects of ability levels on NCE students’ performance when taught biology concepts using computer-animation-package. The study adopted quasi-experimental design. The population for this study comprised 2,594 Biology students in colleges of education in Bauchi State, while the target population was 878 NCE II Biology students. There are four NCE-awarding institutions in the State of which only two run Biology Education programme at the NCE level. Sixty NCE II Biology students participated (42 for experimental of 21 males, 21 females taught using animation-package and 18 for control group of 9 males and 9 females taught with lesson note). Six instruments were developed: animation-package, questionnaire, lesson notes, to-do lists, manual and test. The 6 instruments were validated but only the animation-package test items were pilot tested for reliability. The results were 0.432 for pretest, and 0.001 for posttest. Mean and standard deviation were used to answer research question. Analysis of Variance at 0.05 level of significance. The findings of the study revealed no significant difference in the performance of high ability, medium ability and low ability levels students, when taught biology concepts using computer-animation. The study concluded that computer-animation strategy enhanced NCE students’ academic performance in biology concepts irrespective of their ability levels. The implication is that computer-animation instructional strategies played significant role in the teaching and learning biology concepts among students with different ability levels in colleges of education in Bauchi State, Nigeria. The study recommended that lecturers of Biology in colleges of education to incorporate computer-animation into their teaching

The Mighty Bite by Nathan Hale (review)

Reviewed by: The Mighty Bite by Nathan Hale Ally Byerly Hale, Nathan The Mighty Bite; written and illus. by Nathan Hale. Amulet/Abrams, 2023 [288p] Trade ed. ISBN 9781419765537 $14.99 E-book ed. ISBN 9781647008758 $13.49 Reviewed from digital galleys R Gr. 1-4 Trilobite (an ancient arthropod which falls between a horseshoe crab and a rolypoly) lives happily and humbly on the Island of Losta Founda, a land populated by prehistoric and mythic creatures, until a vivid dream ignites his hunger for fame and fortune. Unfortunately, Trilobite and his companion, Amber the Ambulocetus (an amphibious whale that resembles a crocodile), don't quite know how they'll go about finding fame (an attempt at singing goes terribly awry) until they encounter Tiffany Timber, a paleo-newscaster who wields a taser and a tablet in her hunt for the latest scoop. Trilobite and Amber are quickly drawn into the absurdities of Timber's newscaster world, stumbling from one episodic misadventure to the next and facing everything from a claymation smear campaign to an interview with a [End Page 260] sea cucumber in their quest for fame, fortune, and journalistic integrity. The story's premise is as creative as it is absurd, and the farcical volume is structured like a series of daily strips, replete with silly gags and wry one-liners. Hale's dynamic layouts guide the eye to create a quick, accessible read, and perspective and transitions are skillfully used to produce an immersive, cinematic experience that blurs the boundaries between space, time, and genre. Hand-drawn, heavily cross-hatched illustrations brilliantly juxtapose with the modern video interface of the fame-hungry protagonists without privileging one medium over the other. Instead, the narrative plays on the commonalities between the sequential art forms—from the framing to the timing to the editing, and ultimately pays homage to the timeless craft of storytelling. This will be an absolute treat for any reader who likes their natural history with a side of whimsy. Copyright © 2023 The Board of Trustees of the University of Illinois