Lakes are known as sentinels of climate change, but their responses may differ from one to another leading to different strategies in lake protection. It is particularly the case in the Tibetan Plateau (TP) of multiple hydrological processes. We employed the Budyko framework to study Tibetan lakes from two lake-basins of contrasting climates for the period between 1980 and 2022: Taro Co Basin (TCB) in a sub-arid climate, and Ranwu Lake Basin (RLB) in a sub-humid climate. Our results showed that total lake area, surface air temperature, evapotranspiration, and potential evapotranspiration increased in both lake-basins, while precipitation and soil moisture increased in the TCB but decreased in the RLB. In the Budyko space, two basins had contrast hydroclimatic trajectories in terms of aridity and evaporative index. The TCB shifted from wetting to drying trend, while the RLB from drying to wetting in early 2000s. Notably, lake change was generally consistent with the drying/wetting phases in the TCB, but in contrast with that in the RLB, which can be attributed to warming-induced glacier melting. Despite of significant correlation with the large-scale atmospheric oscillations, it turned to be more plausible if lake area changes were substituted with basin's hydroclimatic trajectories. Among the large-scale oscillations, El Niño-Southern Oscillation (ENSO) is the most dominant control of lake trends and their drying/wetting shifts. Our findings offer a valuable insight into lake responses to climate change in the TP and other regions.