Sensory Responsiveness Research Articles

Sensory modulation difficulties and PTSD: A prospective study during and after rocket attacks.

Civilians in war may suffer from distress not only during the peritraumatic phase, manifested in early trauma-related symptoms, but also after the trauma ends, as reflected in posttraumatic stress disorder (PTSD). Evidence has suggested that early trauma-related symptoms underlie the development of PTSD. Additionally, research has revealed relations between sensory responsiveness and both early trauma-related symptoms and PTSD, thus implying that individuals with sensory modulation difficulties may exhibit elevated symptomatology at the peritraumatic phase and may be at risk for PTSD. Nevertheless, the cross-sectional design of former studies allowed neither identifying the directionality of the relationship between sensory modulation and PTSD nor exploring the role of early trauma-related symptoms within this relationship. The current prospective study, which was aimed at bridging these knowledge gaps, was conducted among a convenience sample of Israeli adults (n = 209) during rocket attacks (T1) and 40-71 days after ceasefire (T2). Background variables, sensory modulation difficulties, early trauma-related symptoms, and PTSD symptoms were assessed online via self-report measures. Results revealed that high sensory responsiveness was related to early trauma-related symptoms and predicted PTSD symptoms of hyperarousal, intrusion, and negative alterations in mood and cognitions. Moreover, early trauma-related symptomatology mediated the relations between high sensory responsiveness and PTSD symptoms of intrusion and negative alterations in mood and cognitions. The current findings suggest that high sensory responsiveness is a risk factor for PTSD and that early trauma-related symptomatology may serve as a mechanism underlying the relationship between high sensory responsiveness and PTSD. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

Altered olfactory responses in Fmr1 KO mice

Fragile X syndrome (FXS) is a neurodevelopmental disorder oftentimes associated with abnormal social behaviors and altered sensory responsiveness. It is hypothesized that the inappropriate filtering of sensory stimuli, including olfaction, can lead to aberrant social behavior in FXS. However, previous studies investigating olfaction in animal models of FXS have shown inconsistent results. Here, we found that Fmr1 knock-out (KO) mice, a mouse model of FXS, showed increased sniffing duration for non-social odors during their first exposure. Additionally, while wild-type (WT) males demonstrated differences in behavioral patterns between non-social odors while Fmr1 KO males did not show such distinction. We also showed that Fmr1 KO males spent significantly less time sniffing female urine odor compared to WT males. Moreover, we found an increased volume of the olfactory bulb in Fmr1 KO males. Overall, our findings suggest that the Fmr1 KO mice demonstrate atypical olfactory behaviors as well as structural changes in the olfactory bulb.

Neuronal subset-specific Pten-deficient mice do not exhibit deficits in sensorimotor gating processes

Background Deficits in sensorimotor gating have been reported in individuals with autism spectrum disorder (ASD), as well as in ASD murine models. However, this behavior has not been examined in the neuronal subset-specific (NS)-Pten knockout (KO) model of ASD. NS-Pten KO mice exhibit hyperactivity of the PI3K/AKT/mTOR signaling pathway which is implicated in the onset of autistic deficits. This study investigates the potential relationship between PI3K/AKT/mTOR signaling and deficits in sensorimotor gating. Methods To assess sensorimotor gating in NS-Pten KO mice we utilized a three-day paradigm. On day 1 (habituation) the mice were administered 80 repetitions of a 120-dB startle stimulus. On day 2, prepulse inhibition was measured with 90 trials of the startle stimulus that was paired with a smaller (2, 7, or 12 dB) prepulse stimulus. Day 3 was assessed one week later, consisting of randomized startle trials and trials with no stimulus and was used to determine the startle response. Results No significant difference between NS-Pten KO or wildtype (WT) mice was found for habituation (p > 0.05). No significant differences were found between groups when assessing the percentage of prepulse inhibition at 2, 7, and 12 dB (p > 0.05). There was also no difference in startle response between groups (p > 0.05). Conclusion Our study found that the NS-Pten KO model does not display significant deficits in sensorimotor gating processes. The present findings help to elucidate the relationship between PI3K/AKT/mTOR hyperactivation and sensory reactivity.

Sensory processing and social participation in children with autism spectrum disorder: A systematic review

Background: Children with autism spectrum disorder experience various challenges, in which difficulties in social participation represent a significant area of concern. Research studies indicate that autistic children who experience more challenges in sensory processing tend to demonstrate lower social competence. Therefore, a comprehensive synthesis of the evidence exploring the link between sensory processing and social participation is needed to develop targeted interventions and support strategies to enhance social functioning in children with autism spectrum disorder. Objective: This systematic review aimed to investigate the impact of sensory processing on social participation in children with ASD aged 3-18 years. Materials and methods: The review involved a comprehensive search across electronic databases such as Scopus, PubMed, and OTseeker. The McMaster Critical Review Form for Quantitative Studies was used to evaluate the methodological quality of the included articles. Results: A total of 4,158 records were identified through database searches and manual searches. Following the title and abstract review, 10 studies were selected for the full-text review, which led to the inclusion of 8 studies in the systematic review that met the predefined criteria. Among the 8 studies, 7 studies reported a significant correlation between sensory processing and social participation in children with ASD. Specifically, sensory over-responsivity, under-responsivity, and seeking behaviors were found to influence the child’s ability to comprehend, interpret, and respond to social cues effectively, thereby increasing the social challenges commonly associated with ASD. Conclusion: This systematic review underscores the evident impact of sensory processing difficulties on social participation among children with ASD. It highlights the critical role of sensory processing in facilitating successful social functioning across diverse contexts and emphasizes its importance in enhancing overall social well-being in children with ASD.

Prospective Interrelation Between Sensory Sensitivity and Fine Motor Skills During the First 18 Months Predicts Later Autistic Features.

Sensory features are included in the diagnostic criteria of autism and atypical sensory responsiveness may produce "cascading effects" on later development. Similarly, autistic individuals often struggle with motor coordination and early delays in the motor domain appear to be linked to later development. However, the longitudinal interrelation between early sensory profiles and motor features on later socio-communicative skills remains to be defined. This study aimed to investigate whether sensory sensitivity impacts fine motor abilities and vice versa from 12 to 18 months of age and to examine how sensory-motor interplay would be associated with later autistic traits at 24-36 months of age. The sample included 118 infant siblings of autistic children recruited at 12 months of age. Sensory sensitivity and eye-hand coordination were assessed at 12 and 18 months of age and autistic traits were evaluated at 24-36 months of age. Cross-lagged panel analysis revealed significant within-domain effects for sensory sensitivity and eye-hand coordination from 12 to 18 months. Furthermore, a significant association between these two domains on later autistic traits was found. In analyzing the longitudinal bidirectional relationship, we found that lower eye-hand coordination skills at 12 months predicted later sensory sensitivity at 18 months, and in turn, social communication skills at 24-36 months. The present study offers new empirical evidence supporting the potential clinical value of including sensory and motor measures besides social communication skills within early autism surveillance programs.

Development and Psychometric Properties of the Pain and Sensitivity Reactivity Scale in a Diverse Sample of Autistic People.

Recent studies indicate the need to examine how the gut microbiota-brain axis is implicated in pain, sensory reactivity and gastro-intestinal symptoms in autism spectrum disorder (ASD), but no scale exists that assesses all these constructs simultaneously. We created a pool of 100 items based on the real-world experience of autistic people, and a multidisciplinary team and stakeholders reduced this pool to 50 items assessing pain, sensory hypersensitivity, and sensory hyposensitivity. In the present study, we present this new assessment tool, the Pain and Sensitivity Reactivity Scale (PSRS), and examine its psychometric properties in a sample of 270 individuals with autism spectrum disorder (ASD; mean age = 9.44, SD = 4.97), of which almost half (45%) had intellectual disability (ID). A factorial model of three factors (pain, hyporeactivity, and hyperreactivity) and five specific factors for sensory hypo- and hyperreactivity, respectively, fitted the data well. Good to excellent internal consistency and adequate test-retest reliability was found for most PSRS scales. Sound psychometric properties were found in individuals with and without ID. Correlations with other measures of sensory sensitivity and pain indicated sound convergent validity. PSRS shows promise as a reliable measure to analyze pain and sensory reactivity in autistic people regardless of whether they have ID or not. The measure overcomes several limitations of previous assessment tools and includes variables that are important for the understanding of the gut microbiota-brain axis in ASD.

Neonatal Eating Assessment Tool-Mixed Breastfeeding and Bottle-feeding: Reference values and factors associated with problematic feeding symptoms in healthy, full-term infants.

The Neonatal Eating Assessment Tool-Mixed Breastfeeding and Bottle-feeding (NeoEAT-Mixed Feeding) is a parent-report assessment of symptoms of problematic feeding in infants who are feeding by both breast and bottle. To establish reference values for the NeoEAT-Mixed Feeding and evaluate factors that contribute to symptoms of problematic feeding in healthy, full-term infants. Parents of 409 infants less than 7 months old completed an online survey. Median and percentile scores are presented for infants aged 0-2, 2-4, 4-6, and 6-7 months old. Neonatal Eating Assessment Tool-Mixed Feeding total score and scores for the Gastrointestinal Tract Function and Energy & Physiologic Stability subscales decreased with increasing infant age. Infant Regulation and Feeding Flexibility subscale scores remained stable over time, whereas Sensory Responsiveness subscale scores increased with increasing infant age. Infants with more gastrointestinal and gastroesophageal symptoms had higher NeoEAT-Mixed Feeding total scores. In healthy, full-term infants, symptoms of problematic feeding generally improve over the first 7 months, with the exception of symptoms related to sensory responsiveness. Gastrointestinal and gastroesophageal reflux symptoms are related to symptoms of problematic feeding. The reported reference values may be used to identify infants in need of further assessment, referral, and intervention. In healthy, full-term infants with concurrent gastrointestinal symptoms and problematic feeding, interventions targeted at gastrointestinal symptoms may help to improve symptoms of problematic feeding as well.

Whole-brain responses to visual and auditory stimuli in anesthetized and minimally restrained awake mice using quiet zero echo time fMRI

Abstract Functional MRI (fMRI) is a flexible tool for sensory perception studies in animal models. However, animal fMRI studies are generally performed under anesthesia. Unfortunately, anesthesia affects brain function and sensory processing, complicating the interpretation of the findings. Since there is a growing need for fMRI protocols applicable for awake animals, we optimized a zero echo time Multi-Band Sweep Imaging with a Fourier Transformation (MB-SWIFT) fMRI approach for imaging awake mice. We implemented a 14-day habituation protocol that resulted in merely moderate motion of the mice while being head-fixed with the animals’ body and limbs being free to move. The sensory responsiveness between different states of consciousness was compared by imaging mice with visual and auditory stimulation schemes in the awake state and under ketamine–xylazine anesthesia. In awake mice, we observed a robust whole-brain activation of the ascending auditory and visual pathways, as well as higher sensory processing areas. Under ketamine–xylazine anesthesia, auditory responses were suppressed, and the temporal shapes of fMRI responses were different from those obtained in awake mice. Our results suggest that the quiet and motion-tolerant zero echo time MB-SWIFT approach allows complex behavioral fMRI designs in the awake state that promise to improve our understanding of the underlying mechanisms of perception.

High-dose Vitamin-B6 reduces sensory over-responsivity.

Sensory reactivity differences are experienced by between 5% and 15% of the population, often taking the form of sensory over-responsivity (SOR), in which sensory stimuli are experienced as unusually intense and everyday function is affected. A potential mechanism underlying over-responsivity is an imbalance between neural excitation and inhibition in which inhibitory influences are relatively weakened. Therefore, interventions that boost neural inhibition or reduce neural excitation may reduce SOR; Vitamin-B6 is the coenzyme for the conversion of excitatory glutamate to inhibitory gamma-aminobutyric acid (GABA), and in animal models, it both increases the concentration of GABA and reduces glutamate. To discover whether taking a high dose of Vitamin-B6 reduces SOR and other aspects of sensory reactivity. We recruited 300 adults (249 females) from the general population who completed the Sensory Processing 3-Dimensions Scale (SP-3D) first at baseline, and again following randomisation to either 1 month's supplementation with 100 mg Vitamin-B6, or one of two control conditions (1000 µg Vitamin-B12 or placebo). To focus on individuals who experience SOR, we analysed the effects of supplementation only on individuals with high baseline SOR scores (above the 87th percentile). In individuals with SOR at baseline, Vitamin-B6 selectively reduced SOR compared to both placebo and Vitamin-B12. We also found that Vitamin-B6 selectively reduced postural disorder in individuals with high scores on this subscale at baseline, but there were no effects on the four remaining SP-3D subscales. Clinical trials and mechanistic studies should now be conducted in autism, attention deficit hyperactivity disorder and other groups with SOR.

Pupillometry reveals hyper-arousal in response to auditory stimuli in autistic children.

Atypical sensory responsivity is widely reported in autistic individuals and is related to elevated functional difficulties. Dynamically, altered initial responses and/or habituation rates could underlie their atypical averaged responses to repeated sensory stimuli. In this study we aimed to measure the arousal level in response to different types of auditory stimuli and the dynamic change of atypical arousal level using pupillometry in autistic children. In Experiment 1, 43 autistic children and 49 neurotypical (NT) children were asked to passively listen to a mild sound and an aversive sound repeatedly. In Experiment 2, 39 autistic children and 44 NT children who went through Experiment 1 listened to a gradually emerging non-startling sound and a suddenly emerging startling sound in a random order. We found that the autistic group showed hyper-arousal in response to the aversive sound and the startling sound as reflected by their larger change in pupil area. In comparison, these autistic children demonstrated normal arousal in response to the mild sound and the non-startling sound. Dynamically, the autistic group had a larger peak pupil area change than the NT group in the first trial and a normal habituation rate to the aversive sound. In summary, our results suggest hyper-arousal to aversive and startling stimuli and the role of larger initial responses in hyper-arousal in autism. Minimizing aversive and startling sensory stimuli or gradually increasing the volume of aversive auditory stimuli to allow autistic children to adapt using the principle of habituation is recommended to reduce the arousal level and problematic behaviors of autistic children.

Auditory gating and its clinical correlates in adults with chronic tic disorder and neurotypical adults

BackgroundOver 80% of adults with chronic tic disorder (CTD) experience sensory over-responsivity (SOR), defined as heightened awareness of and/or behavioral reactivity to commonplace environmental stimuli. One potential mechanism underpinning SOR is sensory gating impairment. Sensory gating is the physiologic process whereby redundant stimuli are filtered out in early perceptual stages. In this study, we compared sensory gating between neurotypical and CTD adults and determined if gating indices associated with SOR. MethodsNeurotypical (n = 31) and CTD adults (n = 26) completed a clinical assessment, including two SOR measures (Sensory Gating Inventory, SGI; Sensory Perception Quotient, SPQ), and an auditory gating paradigm while monitored on EEG. ResultsCTD adults exhibited greater SOR. Neurotypical and CTD adults did not differ in P50, N100, or P200 gating ratios. In regression analyses, N100 gating ratio was significantly associated with SGI score; the magnitude of this association was greater for neurotypical than CTD adults. No other significant associations emerged between gating ratios and SOR measures. ConclusionFindings do not support sensory gating impairment as a mechanism underpinning SOR in CTD.The relationship between N100 gating and SOR warrants further investigation. SignificanceThis is the first study to examine auditory gating in individuals with CTD.

Relationships between sensory reactivity and occupational performance in children with paediatric acute-onset neuropsychiatric syndrome (PANS).

Paediatric acute-onset neuropsychiatric syndrome (PANS) is a neurodevelopmental disorder affecting children's performance in a fluctuating manner. This study investigates the relationship between sensory reactivity and occupational performance in children with PANS during exacerbation phases. Understanding these relationships is crucial for developing tailored interventions and managing the condition effectively. This study is part of a larger project in which a two-period bidirectional case-crossover design was employed to assess sensory reactivity and occupational performance in children with PANS. The current study used data from exacerbation phases only. Parents of children aged 4.6 to 13.1years with PANS were recruited globally, and data were collected via online surveys. The Vineland Adaptive Behaviour Scale (VABS) evaluated occupational performance, and the Sensory Processing Measure (SPM) assessed sensory reactivity. Analysis utilised Pearson correlation to determine the relationships between sensory reactivity and occupational performance domains. Data from 60 participants who completed the SPM and 21 who completed the VABS showed moderate to strong negative correlations between the SPM total and several domain scores (vision, hearing, body awareness, balance, and motion) and the VABS Communication and Daily Living Skills scores, indicating that increased sensory reactivity is associated with decreased occupational performance during exacerbations. No significant correlation was found between sensory reactivity and socialisation skills. Findings highlight the significant relationship between sensory reactivity and occupational performance during PANS exacerbations, particularly in communication and daily living skills domains. Further research is needed to examine factors influencing socialisation skills and to assess the effectiveness of sensory interventions in improving occupational performance. Although there was no direct consumer and community involvement, two researchers on our team have family members with PANS. Their personal experiences provided vital insights into the challenges faced by children with PANS, deeply influencing our study's design, focus, and interpretation, ensuring it reflects the realities of those affected. We examined the relationship between children's daily activities and their sensory reactivity during PANS symptom flare-ups. Parents of children aged 4.6 to 13.1 years completed surveys measuring sensory reactivity and their children's performance of daily tasks. Our findings showed that during symptom flare-ups, children experienced significant difficulties with communication and daily living skills. These challenges were directly related to heightened sensory reactivity during flare-ups. This highlights the importance of providing targeted occupational therapy during these times to help children manage their symptoms and improve their daily functioning.

Association Between Television Viewing and Sensory Reactivity in Childhood: The Cross-Sectional InProS Study

BackgroundCurrent evidence suggests a potential detrimental effect of increased television viewing on children's health, including sensory processing issues. Therefore, this study examined the association between television viewing time and atypical sensory reactivity (SR) in children aged from three to seven years. MethodsWe evaluated data from the InProS cross-sectional study (n = 545). Daily television viewing was categorized into tertiles: ≤1.5, 1.5 to 2.5, and ≥2.5 hours. SR was evaluated using the Short Sensory Profile (SSP). Children with atypical SR were those with a global SSP score below 155, 30 for tactile sensitivity, 15 for taste/olfactory sensitivity, 13 for movement sensitivity, 27 for under-responsive/seeks sensation, 23 for auditory filtering, 26 for low energy/weak, and 19 for visual/auditory sensitivity. We used multiple Poisson regression models with robust variance to explore associations. ResultsAfter adjusting for covariates, children who watched television 1.5 to 2.5 and ≥2.5 hours/day showed a higher prevalence of atypical global SR (prevalence ratio [PR]: 1.54; 95% confidence interval [CI]: 1.03 to 2.30; PR: 1.81; 95% CI: 1.19 to 2.76, respectively) and auditory filtering (PR: 1.50; 95% CI: 1.15 to 1.96; PR: 1.36; 95% CI: 1.01 to 1.83, respectively), compared with children who watched ≤1.5 hours/day. In addition, watching television ≥2.5 hours/day, compared with watching ≤1.5 hours/day, was associated with having atypical SR in movement sensitivity (PR: 1.73; 95% CI: 1.06 to 2.83), under-responsive/seeks sensation (PR: 1.31; 95% CI: 1.02 to1.69), and low energy/weak (PR: 2.02; 95% CI: 1.01 to 4.06). ConclusionsThe findings showed that television viewing ≥1.5 hours/day was associated with a higher prevalence of atypical SR in childhood. However, further longitudinal studies are required to confirm these results.

Functional observational battery (FOB) tests using caffeine and chlorpromazine hydrochloride in sprague-dawley rats.

Caffeine is believed to exert its therapeutic effects by acting as a nonselective, competitive antagonist of adenosine receptors. Chlorpromazine, a phenothiazine, is a classic psychotropic mediator extensively used in the clinical administration of psychotic disorders. This study aimed to validate the procedures used for performing Functional Observational Battery (FOB) tests, to demonstrate the proficiency and interobserver reliability during the FOB tests and also to assess effect on neurobehavioral parameters using positive controls in rats. The rats were administered with Caffeine in Milli-Q water as oral gavage at the dose of 20 mg/kg and Chlorpromazine HCl in 0.9% Saline as intraperitoneal route at the dose of 20 mg/kg. No inter-personnel variability was observed in home cage, handling, open field and sensory reactivity observations recorded in Proficiency test. In conclusion, the known effects of positive controls; caffeine and chlorpromazine HCl on neurobehavioral/Functional Observational Battery parameters including autonomic, neuromuscular and sensory reactivity tests were detected in the current study. FOB test procedures for neurobehavioral, grip strength and motor activity are adequate for the detection of neurotoxic effects of positive controls. No major inter-personnel variability was observed between study personnel in neurobehavioural observations.

Recent onset mental illness severity: pilot study on the role of cognition, sensory modulation, and daily life participation.

Early detection of individuals at risk for onset of severe illness is crucial for prevention and early intervention, aiming to mitigate the long-term impact on both the individual and the community. While well-established models exist for predicting the onset and prolonged severity of illness, there is a gap in understanding illness-onset severity. This pilot study aimed to investigate premorbid objective and subjective dimensions of participation in daily life occupations, as well as sensory and cognitive functions as potential markers of the recent-onset mental illness severity. A total of 50 participants (men: N=26, 52%; women: N=24, 48%), aged 18-40 (M=26.2, SD=5.8) with recent-onset mental illness completed standard, well-established assessments of illness severity, cognitive biases and failures, neurocognitive status, participation in daily life, and sensory responsiveness thorough cross-sectional design. The differences between the groups of the illness severity were explored with descriptive statistics, followed by a Kruskal-Wallis test. Discriminant analysis was used suggesting a multi-varied model for the separation between the groups of illness severity. Three groups of illness severity exhibited differences in premorbid cognitive functions (F(2)=5.8, p<.01) and participation diversity (F(2)=3.8, p<.05). Combining these two indices explained 92% of the variance between the groups (Wilks' Λ = .68, χ2(4) = 17.7, p=.001), accurately classifying mild to marked illness severity (62.5-88.5%). The study contributes to revealing factors involved in the formation of more severe mental illness and suggesting possible avenues for early intervention and prevention. Cognitive biases and sensory modulation dysfunction may contribute to the illness formation. Still, the most effective markers of more severe mental illness onset are functional cognition and limited participation diversity. Since addressing these markers is a unique specialization within occupational therapy, the findings highlight the potential contribution theprofession can make to the early identification of the most vulnerable populations.

The negative association between food neophobia and sensory expectations revealed through analysis of consumers’ open-ended descriptions of seafood

Food neophobia (FN) – the reluctance to try novel foods – may have served a protective, evolutionary function against consuming harmful foods. In modern societies, however, FN is a major barrier that limits dietary variety and negatively impacts acceptance of both new and familiar foods. Using an online survey (adults living in Sweden, n = 946) this study investigated the influence of FN on sensory expectations of five types of seafood (salmon, herring, oysters, octopus, and seaweed; presented as labelled images). Participants rated expected liking, emotional arousal, and perceived familiarity (quantitative scales) and described the sensory aspects they expected to like and dislike using their own words (open-ended responses). The open-ended responses were evaluated qualitatively and categorized into four sensory modalities (appearance, aroma, taste, and texture). Expected liking was highest for salmon (followed by herring, seaweed, and lastly octopus and oysters), and FN was negatively associated with expected liking for all species except salmon, possibly due to being familiar and regularly consumed in Sweden. Logistic regression was used to evaluate whether the likelihood of spontaneously mentioning each sensory modality as liked or disliked varied by species and FN score. This revealed that participants were more likely to mention liking aspects of taste and texture than aroma and appearance for all samples except oysters. Texture was commonly disliked for herring, oysters, and octopus, but not for salmon and seaweed. Higher FN scores increased the likelihood of mentioning all sensory modalities as disliked and decreased the likelihood of mentioning all sensory modalities as liked. Thus, higher levels of FN were associated with both an increased focus on sensory disliking, and lower expected sensory enjoyment across all modalities. These results suggest that FN may be at least partly driven by heightened sensory responsiveness and highlight the importance of understanding expectations prior to tasting.

Sensory Reactivity Through the Lived Experiences of Parents of Children with Autism Spectrum Disorder: An Exploratory Phenomenological Qualitative Study

Background: The current sensory assessment measures for autism spectrum disorder (ASD) have issues related to cultural and clinical applicability, which makes them difficult to apply in the Indian context consistently. The current study aimed to explore locally relevant themes for sensory reactivity in children with ASD. Methods: This exploratory phenomenological qualitative study was carried out on 15 parents of children with ASD visiting the child guidance clinic. An in-depth interview (IDI) guide was prepared on the conceptual framework based on Dunn, as well as, Miller’s models, which was then further refined based upon the inputs from the experts (psychiatrists, child psychologists, speech-language pathologists, and occupational therapists) working with children with ASD. IDIs were conducted with parents of children with ASD. The data was recorded in audio and video format. It was transcribed and translated from Hindi to English. Coding was done manually, and themes were extracted. Results: The findings identified four superordinate themes: sensory hyperreactivity, sensory hyporeactivity, sensory seeking, and socio-emotional response. Conclusion: The lived experience of parents aids in identifying and describing dimensions of sensory reactivity in children with ASD. It will help further in developing a valid and reliable instrument for the assessment of sensory reactivity in children with ASD.

Sensory responsivity and its relation to alexithymia, social processing and restricted interests and repetitive behaviour in autistic children

BackgroundAlthough noted in the earliest descriptions of autism, differences in sensory processing, including hyper-responsivity, hypo-responsivity and sensory seeking, have only been included as a diagnostic criterion more recently. Understanding how these unique features of sensory processing are related to the emotional and social aspects of autism is an ongoing question. Here we ask whether differences in sensory processing are associated with alexithymia, a trait characterised by an inability to identify and describe one’s feelings, which has a high incidence in autism. MethodParents of autistic children (n = 38) and parents of non-autistic children (n = 35) completed four standardized scales, the Short Sensory Profile-2, Social Responsiveness Scale-2, Social Communication Questionnaire, and the Children’s Alexithymia Measure. ResultsAcross all four scales the autistic children showed higher scores than the non-autistic children, with large effect sizes. Using the subscales of the SSP-2 we show that, for the autistic children but not for the non-autistic children, sensory hyper-responsivity is predictive of alexithymia, of core social features of autism and of restricted interests and repetitive behaviour (RIRB), after controlling for hypo-responsivity and sensory seeking. ConclusionsThese results add to a small but growing literature on the relationship between sensory processing and social and emotional behaviours in autistic children, and are discussed with reference to predictive coding and ‘sensory first’ accounts of autism. As sensory differences in autism impact children’s daily functioning and educational opportunities, understanding how these differences relate to social and emotional behaviour is important.

Development of dental clinic cooperativity predictor instrument for children with autism spectrum disorder

Background: A survey to identify factors affecting the cooperation of children with autism spectrum disorder (ASD) in Indonesia is crucial for enhancing this group’s dental care, oral health, and overall quality of life. However, limited culturally relevant instruments hinder such research. Purpose: This study aims to determine the essential domain needed to design a questionnaire instrument that can predict the cooperativity of children with ASD during dental procedures. Methods: Based on the literature and existing questionnaires, the newly developed questionnaire underwent forward–back translation, before being thoroughly reviewed by an expert committee. The response format, content, and question clarity were evaluated. A cross-sectional study with 30 parents of children with ASD was randomly conducted to test the questionnaire. The validity of each question was measured by the Pearson product-moment correlation coefficient, while its reliability was assessed by Cronbach’s alpha. Results: Each question within the domain showed varying degrees of validity: reading ability (r = 0.658), daily communication (r = 0.541), involvement in social activity (r = 0.360), daily self-care ability (r = 0.506), emotional status (r = 0.426), sensory responsiveness (r = 0.615), language comprehension (r = 0.362), and permission to be touched on the head at a barbershop (r = 0.458). The questions were found to be reliable (Cronbach’s alpha, r = 0.645 &gt; 0.306). Conclusion: As prediction tools for assessing the cooperativity of children with ASD during dental procedures, the questionnaire should include the following items: communication and reading abilities, daily self-care, social activity, emotional status, sensory responsiveness and permission to be touched on the head at a barbershop.

Cross-Cultural Validity of the Sensory Health Awareness &amp; Responsiveness Profile (SHARP)

Abstract Date Presented 03/21/24 This study cross-culturally validated the Sensory Health Awareness and Responsiveness Profile (SHARP). Differences stress the need to further explore the relationships between constructs of sensory health and culture. Primary Author and Speaker: Liat Hen-Herbst Additional Authors and Speakers: Sonya Meyer, Catherine Cavaliere