Sensory Exposure Research Articles

Non-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain

BackgroundFeline osteoarthritis (OA) leads to chronic pain and somatosensory sensitisation. In humans, sensory exposure can modulate chronic pain. Recently, electroencephalography (EEG) revealed a specific brain signature to human OA. However, EEG pain characterisation or its modulation does not exist in OA cats, and all EEG were conducted in sedated cats, using intradermal electrodes, which could alter sensory (pain) perception. New methodCats (n=11) affected by OA were assessed using ten gold-plated surface electrodes. Sensory stimuli were presented in random orders: response to mechanical temporal summation, grapefruit scent and mono-chromatic wavelengths (500 nm-blue, 525 nm-green and 627 nm-red light). The recorded EEG was processed to identify event-related potentials (ERP) and to perform spectral analysis (z-score). ResultsThe procedure was well-tolerated. The ERPs were reported for both mechanical (F3, C3, Cz, P3, Pz) and olfactory stimuli (Cz, Pz). The main limitation was motion artifacts. Spectral analysis revealed a significant interaction between the power of EEG frequency bands and light wavelengths (p<0.001). All wavelengths considered, alpha band proportion was higher than that of delta and gamma bands (p<0.044), while the latter was lower than the beta band (p<0.016). Compared to green and red, exposure to blue light elicited distinct changes in EEG power over time (p<0.001). Comparison with existing methodThis is the first demonstration of EEG feasibility in conscious cats with surface electrodes recording brain activity while exposing them to sensory stimulations. ConclusionThe identification of ERPs and spectral patterns opens new avenues for investigating feline chronic pain and its potential modulation through sensory interventions.

"Still work?" Design and effect of interventions used to modify feeding problems in children with autism: A systematic review of studies employing group designs.

Feeding problems in children with autism jeopardize the well-being of both children with autism and their families. Mixed findings were reported from previous interventions, which were mostly evaluated by single subject research design (SSRD) studies. Moreover, feasibility assessment and social validity measurement were unaddressed by these SSRD studies. To fill this substantial knowledge gap, the present review systematically summarized and evaluated feeding interventions implemented in children with autism, which were assessed by studies employing group designs. An extensive literature search in eight established online databases was conducted, and a total of 17 eligible studies published in 2009-2021 were included for further analysis. A descriptive account of the features of the investigations is provided, including assessment of study quality. A total of 449 children with autism and 203 parents/caregivers participated in the included studies. The multiple use of five strategic intervention components were highlighted in this review, including nutrition education/consultations, environmental modifications, sensory exposure, cognitive components, and behaviour interventions. The reviewed interventions showed a preliminarily positive effect for modifying feeding problems in children with autism. Furthermore, the evaluation based on the RE-AIM framework (reach, efficacy, adoption, implementation, and maintenance) demonstrated that an interdisciplinary multi-component intervention strategy may achieve high effectiveness and feasibility in improving feeding problems in a wide range of children with autism. This review found that interventions achieved and maintained a positive effect on modification of feeding problems in groups of children with autism. Information and gaps identified and summarized in the implementation process may assist both researchers and stakeholders to further support these vulnerable children.

Social experiences shape song preference learning independently of developmental exposure to song.

Communication governs the formation and maintenance of social relationships. The interpretation of communication signals depends not only on the signal's content but also on a receiver's individual experience. Experiences throughout life may interact to affect behavioural plasticity, such that a lack of developmental sensory exposure could constrain adult learning, while salient adult social experiences could remedy developmental deficits. We investigated how experiences impact the formation and direction of female auditory preferences in the zebra finch. Zebra finches form long-lasting pair bonds and females learn preferences for their mate's vocalizations. We found that after 2 weeks of cohabitation with a male, females formed pair bonds and learned to prefer their partner's song regardless of whether they were reared with ('normally reared') or without ('song-naive') developmental exposure to song. In contrast, females that heard but did not physically interact with a male did not prefer his song. In addition, previous work has found that song-naive females do not show species-typical preferences for courtship song. We found that cohabitation with a male ameliorated this difference in preference. Thus, courtship and pair bonding, but not acoustic-only interactions, strongly influence preference learning regardless of rearing experience, and may dynamically drive auditory plasticity for recognition and preference.

Healing Architecture in Birthing Rooms: A Scoping Review.

The purpose of this scoping review is to map the knowledge about the multisensory birthing room regarding the birth experience and birth outcomes. The concept of multisensory birthing rooms is relatively novel, making it relevant to explore its impact. Five databases were searched. The search was limited to articles in English, Danish, Norwegian, and Swedish. There were no time limitations. Fourteen relevant articles were identified providing knowledge about multisensory birthing rooms. Eight articles focused on birth experience, six articles focused on birth outcome, and one on the organization of the maternity care. Seven of the studies identified that sensory birthing rooms have a positive impact on the birth experience and one qualitative study could not demonstrate a better overall birth experience. Five articles described an improvement for selected birth outcomes. On the other hand, a randomized controlled trial study could not demonstrate an effect on either the use of oxytocin or birth outcomes such as pain and cesarean section. The definition and description of the concept weaken the existing studies scientifically. This scoping review revealed that multisensory birthing rooms have many definitions and variations in the content of the sensory exposure; therefore, it is difficult to standardize and evaluate the effect of its use. There is limited knowledge concerning the multisensory birthing room and its impact on the birth experience and the birth outcome. Multisensory birthing rooms may have a positive impact on the birth experience. Whereas there are conflicting results regarding birth outcomes.

The Development of Multisensory Integration at the Neuronal Level.

Multisensory integration is a fundamental function of the brain. In the typical adult, multisensory neurons' response to paired multisensory (e.g., audiovisual) cues is significantly more robust than the corresponding best unisensory response in many brain regions. Synthesizing sensory signals from multiple modalities can speed up sensory processing and improve the salience of outside events or objects. Despite its significance, multisensory integration is testified to be not a neonatal feature of the brain. Neurons' ability to effectively combine multisensory information does not occur rapidly but develops gradually during early postnatal life (for cats, 4-12weeks required). Multisensory experience is critical for this developing process. If animals were restricted from sensing normal visual scenes or sounds (deprived of the relevant multisensory experience), the development of the corresponding integrative ability could be blocked until the appropriate multisensory experience is obtained. This section summarizes the extant literature on the development of multisensory integration (mainly using cat superior colliculus as a model), sensory-deprivation-induced cross-modal plasticity, and how sensory experience (sensory exposure and perceptual learning) leads to the plastic change and modification of neural circuits in cortical and subcortical areas.

The Impact of Physical and Environment Factors on Parental Presence for Oral Feeding in New Zealand Neonatal Intensive Care Units.

To identify physical environmental factors influencing family involvement in feeding in New Zealand neonatal units. Infant oral feeding development is critical for both short-term feeding skills and longer term neurodevelopmental outcomes. The neonatal environment is well-known as challenging for neuroprotection due to negative sensory exposure. The impact of environmental factors on oral feeding in New Zealand (NZ) neonatal units is currently unexplored, and knowledge of this could allow for evidence-based unit design. Focused ethnography at five neonatal units, a national survey of NZ neonatal professionals (n = 102), and five focus groups were carried out. Current oral feeding practice, and beliefs, experiences, and opinions of unit staff and family about these practices were explored. Data were analyzed using qualitative content analysis. Units were providing the best experience to families that they could with the resources they had available. Lack of physical space, lack of privacy, limited on-site accommodation for families, and lack of coordination between maternity and neonatal services were identified as impacting on family's comfort and sense of homeliness on the unit. Unit staff used furniture, screens, and external accommodation providers to support families where they could. The physical design of neonatal units in New Zealand provides barriers to family's spending time privately developing oral feeding. Solutions are proposed to increase the size of bedspaces, provide single-family rooms, create greater on-site family accommodation options, combine maternity and neonatal healthcare, and improve family comfort and therefore connection with their infant.

Neural Signatures of Predictive Strategies Track Individuals Along the Autism-Schizophrenia Continuum.

Humans develop a constellation of different representations of the external environment, even in the face of the same sensory exposure. According to the Bayesian framework, these differentiations could be grounded in a different weight assigned to prior knowledge vs. new external inputs in predictive inference. Since recent advances in computational psychiatry suggest that autism (ASD) and schizophrenia (SSD) lie on the two diametric poles of the same predictive continuum, the adoption of a specific inferential style could be routed by dispositional factors related to autistic and schizotypal traits. However, no studies have directly investigated the role of ASD-SSD dimension in shaping the neuro-behavioral markers underlying perceptual inference. We used a probabilistic detection task while simultaneously recording EEG to investigate whether neurobehavioral signatures related to prior processing were diametrically shaped by ASD and SSD traits in the general population (n = 80). We found that the position along the ASD-SSD continuum directed the predictive strategies adopted by the individuals in decision-making. While proximity to the positive schizotypy pole was associated with the adoption of the predictive approach associated to the hyper-weighting of prior knowledge, proximity to ASD pole was related to strategies that favored sensory evidence in decision-making. These findings revealed that the weight assigned to prior knowledge is a marker of the ASD-SSD continuum, potentially useful for identifying individuals at-risk of developing mental disorders and for understanding the mechanisms contributing to the onset of symptoms observed in ASD and SSD clinical forms.

Drosophila Free-Flight Odor Tracking is Altered in a Sex-Specific Manner By Preimaginal Sensory Exposure.

In insects such as Drosophila melanogaster, flight guidance is based on converging sensory information provided by several modalities, including chemoperception. Drosophila flies are particularly attracted by complex odors constituting volatile molecules from yeast, pheromones and microbe-metabolized food. Based on a recent study revealing that adult male courtship behavior can be affected by early preimaginal exposure to maternally transmitted egg factors, we wondered whether a similar exposure could affect free-flight odor tracking in flies of both sexes. Our main experiment consisted of testing flies differently conditioned during preimaginal development in a wind tunnel. Each fly was presented with a dual choice of food labeled by groups of each sex of D. melanogaster or D. simulans flies. The combined effect of food with the cis-vaccenyl acetate pheromone (cVA), which is involved in aggregation behavior, was also measured. Moreover, we used the headspace method to determine the "odorant" identity of the different labeled foods tested. We also measured the antennal electrophysiological response to cVA in females and males resulting from the different preimaginal conditioning procedures. Our data indicate that flies differentially modulated their flight response (take off, flight duration, food landing and preference) according to sex, conditioning and food choice. Our headspace analysis revealed that many food-derived volatile molecules diverged between sexes and species. Antennal responses to cVA showed clear sex-specific variation for conditioned flies but not for control flies. In summary, our study indicates that preimaginal conditioning can affect Drosophila free flight behavior in a sex-specific manner.

The impact of familiarity on cortical taste coding

The role of the gustatory region of the insular cortex in mediating associative taste learning, such as conditioned taste aversion, has been well studied. However, while associative learning plays a role in some taste behaviors, such as avoiding toxins, animals often encounter taste stimuli in their natural environment without explicit consequences. This type of inconsequential experience with sensory stimuli has been studied in other sensory systems, generally with the finding that neuronal responses habituate with repeated sensory exposure. This study sought to determine the effect of taste familiarity on population taste coding in the mouse gustatory cortex (GC). Using microendoscope calcium imaging, we studied the taste responses of visually identifiable neurons over 5days of taste experience, during which animals could freely choose to consume taste stimuli. We found that the number of active cells in the insular cortex, as well as the number of cells characterized as taste-responsive, significantly decreased as animals became familiar with taste stimuli. Moreover, the magnitude of taste-evoked excited responses increased while inhibited responses decreased with experience. By tracking individual neurons over time, we identified a subpopulation of stable neurons present on all days of the taste familiarity paradigm and further characterized their taste coding properties. The population-level response across these stable cells was distinct for each taste quality when taste stimuli were novel, but population responses for readily consumed stimuli became more correlated as the stimuli became familiar. Overall, these results highlight the effects of familiarity on both taste-specific and non-taste responses in the gustatory cortex.

Nonlinear functional muscle network based on information theory tracks sensorimotor integration post stroke

Sensory information is critical for motor coordination. However, understanding sensorimotor integration is complicated, especially in individuals with impairment due to injury to the central nervous system. This research presents a novel functional biomarker, based on a nonlinear network graph of muscle connectivity, called InfoMuNet, to quantify the role of sensory information on motor performance. Thirty-two individuals with post-stroke hemiparesis performed a grasp-and-lift task, while their muscle activity from 8 muscles in each arm was measured using surface electromyography. Subjects performed the task with their affected hand before and after sensory exposure to the task performed with the less-affected hand. For the first time, this work shows that InfoMuNet robustly quantifies changes in functional muscle connectivity in the affected hand after exposure to sensory information from the less-affected side. > 90% of the subjects conformed with the improvement resulting from this sensory exposure. InfoMuNet also shows high sensitivity to tactile, kinesthetic, and visual input alterations at the subject level, highlighting its potential use in precision rehabilitation interventions.

Feasibility of Implementing a Modified SENSE Program to Increase Positive Sensory Experiences for Preterm Infants in the Neonatal Intensive Care Unit (NICU): A Pilot Study

Aims To evaluate the feasibility of implementing the Supporting and Enhancing NICU Sensory Experiences (SENSE) program with adaptations to increase positive sensory exposure for infants born preterm, support neonatal neurodevelopment, and decrease parent stress. Methods Eight infants born between 28 and 33 weeks were recruited within one week of birth. Parents, trained in the program, delivered the SENSE protocol. The first author provided up to 1 h of sensory input on weekdays when a parent could not be present. Results Recruitment and retention rates were 87.5% and 100%, respectively. Recruitment and initial parent education and training averaged 37.5 min. On average, parents were present in the NICU 85.1% of days; they participated in SENSE for an average of 515.5 min. SENSE dose recommendations were not consistently met. Weekly infant assessments and regular parent check ins averaged 22.5 and 13.8 min, respectively. Post-assessments revealed normal scores on a neurodevelopmental assessment, low parent stress, and high parent satisfaction. Conclusions The recruitment and retention rates suggest high demand to participate. Outcomes for parent stress and neonatal neurodevelopment support continuation of SENSE. Time commitment for implementation, coupled with supporting families in meeting dose recommendations, suggest a need for a neonatal therapist to promote sustainability.

Promoting Healthy Lifestyles and Well-Being in Autistic Youth.

According to data from the National Health and Examination Survey, ∼40% of adults and 19% of youth in the United States were obese in 2015 and 2016, with a disproportionate burden seen in non-Hispanic Black and Hispanic youth when compared with non-Hispanic White and non-Hispanic Asian youth.1 The etiology of the obesity epidemic is complex and multifaceted, spanning physiologic, behavioral, genetic, social–emotional, political, and economic factors. As the epidemiology of morbidity and mortality has shifted from infectious to chronic and, most often, preventable diseases, the importance of healthy lifestyle behaviors for all families, including autistic individuals, could not be more pressing.Autistic children and adolescents are at disproportionate risk for unhealthy weight status and represent just one of many communities with unique considerations when it comes to tailoring interventions designed to improve nutrition and physical activity.2,3 Restrictive eating behaviors, sensory issues, specialized diets, social and behavioral impairments, motor impairments, and family factors are key considerations in addressing barriers to optimal nutrition and physical activity in autistic children.4–6 For American Black and Hispanic/Latinx families with autistic children, a history of structural racism and the generation of limiting social structures further complicate efforts at healthier living via the disproportionate burden of food insecurity, food deserts, and safe built environments they share. Multifaceted interventions offering touchpoints in multiple social arenas (ie school, church, home, community center) that are tailored to the needs and strengths of diverse communities will be required for meaningful and effective change for families with autistic individuals.7Lifestyle medicine focuses on 6 key tenets of health: (1) whole food, plant-based diet, (2) regular physical activity, (3) restorative sleep, (4) stress management, (5) social connectedness, and (6) avoiding risky substance use. When optimized, these 6 tenets can prevent and even help reverse chronic diseases such as cardiovascular disease, diabetes, and cancer. Our goal is to pursue interventions that, first and foremost, use the local autistic community’s input to guide the development and implementation of interventions aimed at improving the lifestyle of autistic individuals and their families. By prioritizing creative educational delivery methods such as a virtual teaching kitchen that promotes social engagement, sensory exposure to a variety of foods, and meal preparation skills that promote self-care and independent living skills, we aim to promote whole-person growth and wellness.The coronavirus disease 2019 pandemic has undoubtedly altered every family’s life in deep and meaningful ways. It has also spurred and required innovative solutions, including the explosive growth of virtual meeting platforms, whose use will require continued input from autistic youth and their families for the development of best practices. Virtual platforms provide expansive virtual reach to autistic youth and families in a variety of historically underserved settings such as rural and urban underserved areas. By funding small-scale pilots, enabling researchers to engage with a network of collaborating research entities, and providing a centralized data infrastructure, the lifestyle node of the Autism Intervention Research Network on Physical Health is poised to scale and more robustly evaluate novel interventions.

Comparing attribute-based and memory-based preferential choice

Common theories of multiattribute preferential choice predict that people choose options that have on average better attribute values than alternative options. However, following an alternative memory-based view on preferences people might sometimes prefer options that are more similar to memorized options that were experienced positively in the past. In two incentivized preferential choice experiments (N = 32, N = 28), we empirically compare these theoretical accounts, finding support for the memory-based value theory. Computational modeling using predictive model comparison showed that only a few participants could be described by a model that uses sums of subjectively weighted attribute values when experience was available. Most participants’ choices resembled the predictions of the memory-based model, according to which preferences are based on the similarity between novel and old memorized options. Further, people whose experience consisted of direct sensory exposure, like tasting a portion of food, were also those with higher likelihoods of a memory-based process, compared to people whose exposure was indirect. These results highlight the central role of memory and experience in preferential choices and add to the growing evidence for memory and similarity-based processes in the domain of human preferences.

The BALANCE nutrition education intervention for adolescents with ASD: A formative study in a school setting

BackgroundAdolescents with autism spectrum disorder (ASD) may consume fewer types of foods overall and consume more processed foods than their typically developing peers. This study aimed to collect formative data to develop an eight-week school-based nutrition intervention for adolescents with ASD (Phase I) and to examine the feasibility and acceptability of the intervention in a school setting (Phase II). MethodFocus groups, interviews, surveys, and feasibility testing of outcome measures (dietary intake, psychosocial determinants, height, weight) were conducted. Eleven adolescents and nine parents participated in formative focus groups and interviews, and twelve adolescents participated in a subsequent pilot intervention of BALANCE (Bringing Adolescent Learners with Autism Nutrition and Culinary Education). Lessons included group-based activities and tasting sessions and lasted 45−50-min. Descriptive statistics and thematic analysis were conducted. ResultsAdolescents and parents discussed the importance of having social modeling, visual cues, and student-led initiatives in a nutrition intervention. BALANCE lessons were administered with 100 % adherence, high quality, and 100 % exposure. On average, 11 students attended the intervention lessons (ranged 10–12). Participants reported that the intervention was acceptable; sensory exposure was an important component. ConclusionsInstrument feasibility varied by age and social communication skill level, suggesting that measures should be carefully selected. The BALANCE intervention was feasible to implement and acceptable to adolescents with ASD.

Sensory Specific Desires. The Role of Sensory Taste Exposure in Desire for Food with a Similar or Different Taste Profile.

The present study investigated how the sensory taste profile of a meal altered the subjective desire, wanting and liking of foods with a sweet, salty, sour, bitter, fatty, and spicy sensory profile, respectively. Participants (n = 85) ate a meal with a pronounced sensory taste profile: (1) sweet, (2) salty, or (3) sweet and salty combined. Self-reports of appetite, pleasantness, and sensory specific desires (SSD) were evaluated over the course of the meal using VAS-scales. SSDs were further studied through alterations in liking and desire for food samples with the main sensory profile being sweet (peach), salty (pretzel), sour (green apple), bitter (dark chocolate), fatty (whipped cream), and spicy (chilli nut), respectively. Consumption of food with a pronounced sensory taste profile was found to suppress the desire for food with a similar sensory taste profile, while the desire for different sensory profiles were enhanced or not affected. Further, when exposed to two pronounced tastes within the same meal, suppression of sensory desires was not only specific for the exposure tastes but tended to go beyond the sensory exposure. The findings suggest that taste variation within a meal holds the potential to create more satisfying meals, which can hinder additional desires after a meal and thus, lower additional calorie intake.

VeggieSense: A non-taste multisensory exposure technique for increasing vegetable acceptance in young children

Vegetable consumption falls well below recommended levels for children in the UK. Previous research has found that repeated non-taste sensory exposure over the course of several days increases young children's willingness to touch and taste vegetables. The current study examined the impact of a one-off multisensory non-taste exposure intervention that took place on a single day on children's willingness to taste and intake of the exposed vegetables. Children (N = 110) aged 3- to 4-years-old were assigned to one of three intervention groups or to a control group. Children in all groups participated individually in a single activity session delivered in their nursery. Children in the intervention conditions took part in fun activities that provided either (a) visual exposure, (b) smell and visual exposure, or (c) smell, touch and visual exposure to six raw and prepared vegetables. Children in the control group engaged in a visual exposure activity with non-food items. After the exposure activities, all children were offered the prepared vegetables to eat; their willingness to taste and intake of the vegetables were measured. Results confirmed previous findings of sensory exposure activities increasing children's willingness to taste and intake of vegetables and revealed linear trends in both measures of acceptance with the number of senses engaged; children who took part in smell, touch and visual activities showed the highest level of acceptance. Findings suggest that multisensory exposures are effective in increasing consumption of vegetables in young children and that the effect of sensory exposure to healthy foods may be cumulative, with the more senses engaged prior to offering a food, the better.

Songbirds are excellent auditory discriminators, irrespective of age and experience

Human infants but not adults possess the ability to perceive differences between non-native language phoneme categories. The predominant explanation for this age-related decline in discriminative ability is the effect of statistical learning driven by sensory exposure: phoneme categories of the native language take precedence, have a higher frequency of occurrence and may encompass category distinctions in non-native languages. Alternatively, one could explain the decline through a reduction in discriminative abilities attributable to ageing. Thus, to what extent is auditory perception influenced either by experience or by age-related processes? Here, we attempted to answer this question, which cannot easily be disentangled in humans, in songbirds, which share many properties with humans: both learn the statistical distribution of sounds in their environment, both possess neural circuits to process vocalizations of their own species and plasticity in these circuits is subject to critical periods. To study the effects of experience and ageing, we trained zebra finches, Taeniopygia guttata , to discriminate short from long versions of a single zebra finch song syllable type. Birds in four groups distinguished by their age (old versus young) and level of auditory experience (with song experience versus completely isolated from song) could learn to discriminate arbitrarily fine differences between song syllables, although we found a trend that upholds the statistical learning hypothesis: birds with song experience performed better than birds with no experience. Furthermore, birds in all groups were able to generalize their learning to new stimuli of the same type, and they were able to rapidly adapt their learned discrimination boundaries. Finally, we found that songbirds could accurately discriminate randomly selected renditions of a stereotyped adult song syllable, revealing a flexible ability to discriminate conspecific vocalizations. • Sensory experience matters more than age for auditory perception in songbirds. • Songbirds generalize learned categories to novel stimuli. • Learned categories are flexible and category boundaries can be relearned easily. • Songbirds can learn random categories accurately. • Their auditory systems represent species-specific sounds accurately and flexibly.

Application of nanobiosensor in food-A comprehensive review

Nanotechnology plays a vital role in the development of biosensors. The sensitivity and performance of biosensors are better-quality by using nanomaterials through new signal transduction technologies. The food products which are spoiled exhibit odours, colours or other sensory characteristics which can be easily discerned by consumers. But when the foods are packed, the packaging material prevent sensory exposure from the foods and hence consumers must trust on expiry dates provided by producers based on a set of idealized assumptions about the way that the food is stored or transported. Nanosensors offer solutions to this problem through their unique chemical and electrooptical properties. Nanosensors can be used to determine microbes, pollutants contaminants etc. and ultimately the freshness of the food. This paper review the status of the various types nanobiosensors and their applications in food. Keywords: Biosensor, E. coli, Staphylococcal enterotoxin, Salmonella, Mycotoxins, GMO

An observational study of sound exposure in a single-room configured neonatal unit (SENSE study)

AimTo measure sound exposure in an Australian single-room configured, neonatal unit and compare findings to current sound level recommendations. MethodsSound meters were placed inside 51 internal environments (incubators or open cots), and within the surrounding environment of each occupied single room between September 15 and October 28, 2015. One-second incremental monitoring of decibels on an A-weighted scale (dBA), occurred over a minimum of 48 h. ResultsAll equivalent continuous sound pressure levels (Leq) were significantly higher than the recommended 45 dBA for both incubators and open cots. Maximum sound levels (Lmax) were significantly higher than the recommended 65 dBA, peaking at 126.7 dBA inside the incubator and 124.7 dBA inside the open cot. Incubators were observed to have a higher total percentage of time above 45 dBA than open cots for both day (99.84% vs. 75.59%) and night (98.66% vs. 59.56%). ConclusionSound levels exceeded the recommended maximum exposure levels outlined by the American Academy of Pediatrics (AAP). The long-term sequelae of adverse sensory exposure on preterm neurodevelopment remains unclear. Renewed attention on factors contributing to increased sound levels in neonatal units needs to be a clinical priority.

Manipulations of sensory experiences during development reveal mechanisms underlying vocal learning biases in zebra finches.

Biological predispositions in learning can bias and constrain the cultural evolution of social and communicative behaviors (e.g., speech and birdsong), and lead to the emergence of behavioral and cultural "universals." For example, surveys of laboratory and wild populations of zebra finches (Taeniopygia guttata) document consistent patterning of vocal elements ("syllables") with respect to their acoustic properties (e.g., duration, mean frequency). Furthermore, such universal patterns are also produced by birds that are experimentally tutored with songs containing randomly sequenced syllables ("tutored birds"). Despite extensive demonstrations of learning biases, much remains to be uncovered about the nature of biological predispositions that bias song learning and production in songbirds. Here, we examined the degree to which "innate" auditory templates and/or biases in vocal motor production contribute to vocal learning biases and production in zebra finches. Such contributions can be revealed by examining acoustic patterns in the songs of birds raised without sensory exposure to song ("untutored birds") or of birds that are unable to hear from early in development ("early-deafened birds"). We observed that untutored zebra finches and early-deafened zebra finches produce songs with positional variation in some acoustic features (e.g., mean frequency) that resemble universal patterns observed in tutored birds. Similar to tutored birds, early-deafened birds also produced song motifs with alternation in acoustic features across adjacent syllables. That universal acoustic patterns are observed in the songs of both untutored and early-deafened birds highlights the contribution motor production biases to the emergence of universals in culturally transmitted behaviors.