Autism spectrum disorder (ASD) presents intricate challenges in managing oral and dental health, necessitating a comprehensive understanding of its diverse manifestations and associated difficulties. Despite the absence of specific oral peculiarities directly linked to ASD, individuals diagnosed with ASD often experience poorer oral health outcomes compared to the general population. Factors such as sensory sensitivities, communication barriers, and behavioral challenges contribute to difficulties in maintaining optimal oral hygiene, resulting in a higher prevalence of teeth decay. Furthermore, children with ASD exhibit unique challenges during dental visits, including sensory aversions, communication difficulties, and behavioral issues, necessitating tailored interventions and accommodations by dental professionals. The collaboration between parents, dentists, and other healthcare providers is essential in addressing the oral health needs of individuals with ASD, emphasizing the importance of a multidisciplinary approach. Despite ongoing research efforts to elucidate the intricacies of oral health in ASD, conflicting findings underscore the complexity of the topic and highlight the need for further investigation. By prioritizing oral and dental health management and fostering collaborative partnerships between caregivers and healthcare professionals, it is possible to enhance the quality of life and well-being of individuals with ASD. To achieve this, targeted interventions should be developed to address the unique challenges faced by individuals with ASD in oral hygiene practices and dental care settings. Ultimately, raising awareness among parents and healthcare providers about the significance of oral health in individuals with ASD is crucial for promoting preventive measures and ensuring access to appropriate dental care services.