This research paper provides a comprehensive review of the role of holistic learning in cultivating global citizenship skills. The paper explores the impact of holistic learning approaches on the development of intercultural competence, social justice awareness, environmental stewardship, and civic engagement among students. Through a thorough literature review, the paper examines the theoretical perspectives, practical applications, and empirical evidence supporting the integration of holistic learning in global citizenship education. The findings consistently demonstrate that holistic learning approaches, such as project-based learning, experiential learning, and integrated curriculum, offer unique benefits in fostering global citizenship skills. By providing students with real-world experiences, interdisciplinary perspectives, and hands-on activities, holistic learning engages students in active learning, critical thinking, and reflection. It promotes intercultural understanding, empathy, effective communication, social justice awareness, environmental stewardship, and a sense of civic responsibility. The paper compares and contrasts holistic learning approaches with other educational approaches, highlighting the distinctiveness and added value of holistic learning in providing a comprehensive and immersive educational experience for global citizenship education. In summary, this research paper contributes to the understanding of how holistic learning can effectively cultivate global citizenship skills, enabling individuals to become responsible and active global citizens in an interconnected world.