Senile Women Research Articles

超高齢女性に発症した自己免疫性肝炎の1例

超高齢女性に発症した自己免疫性肝炎の1例

Chronic low and high back pain in senile women

Chronic low and high back pain in senile women

中・高年女性の骨病変（骨量減少）頻度調査と骨粗しょう症患者へのアルファカルシドールとカルシトニン併用による骨量増加作用の検討

中・高年女性の骨病変（骨量減少）頻度調査と骨粗しょう症患者へのアルファカルシドールとカルシトニン併用による骨量増加作用の検討

Measurement of bone mineral density in osteoporotic fractures of the spine using dual energy X-ray absorptiometry.

The authors analyzed bone mineral density (BMD) in 283 postmenopausal and senile women using dual energy x-ray absorptiometry from March 1990 to April 1992. Bone mineral density of the vertebral body in the osteoporotic fracture group was compared with that in the osteoporotic group to investigate the correlation among BMD, age distribution, and fracture type, and to estimate fracture threshold in the osteoporotic fracture group. BMD decreased rapidly (10%) from 50 and 60 years of age and decreased slowly after 60 years of age; osteoporotic spine fractures were found in 98 cases (35%); there was significant difference in BMD between the osteoporotic group and osteoporotic fracture group; there was no spine fracture when BMD was above 1.00 g/cm2; fracture threshold was 0.85 g/cm2 at the 90th percentile; BMD in multiple spine fracture and old fracture groups was lower than in the single and fresh fracture groups and this was statistically significant. We have concluded that when BMD decreases to less than 0.85 g/cm2, the risk of osteoporotic vertebral fractures escalates rapidly. Postmenopausal and senile women with BMD less than this fracture threshold should receive prophylaxis for osteoporotic fracture.

Measurement of Bone Mineral Density in Osteoporotic Fracture of the Spine using Dual Energy X-ray Absorptiometry: Evaluation of 154 Postmentopausal and senile Women

Measurement of Bone Mineral Density in Osteoporotic Fracture of the Spine using Dual Energy X-ray Absorptiometry: Evaluation of 154 Postmentopausal and senile Women

Clinical Management of Delirium

Delirium is frequently overlooked, its protean symptoms varying widely from patient to patient. The quietly confused man after prostatectomy may be dismissed as senile, the tense and emotional woman with chronic obstructive lung disease labelled as “always a nervous person” The possibility that such persons suffer from a psychiatric disturbance of recent onset and amenable to therapy must not be overlooked.

Neurosecretory phenomenon of the paraventricular nucleus in a senile woman.

Nucleus paraventricularis of a senile woman died of bleeding in the medulla oblongata was histologically examined by means of Gomori's chrome-alum hematoxylin and phloxine method. Neurosecretory material was rare within the cells of the nucleus, while intracellular vacuoles and perinuclear clear area were observed, and cells with red pyknotic nuclei were occasionally found. Brief comments were made with respect to the present finding with reference to the secretory activity of the nucleus.

The Effects of Estrogen Administration Upon Epidermal Proliferation

Contradictory effects on thickness of the skin have been observed during stages in the estrous cycle of rodents and following administration of estrogens. H. F. Bullough (1) and W. S. Bullough (2) found increased proliferation and thickening of the epidermis during high estrogen phases of the estrous cycle in female mice, and were able to induce artificially increased mitotic activity during diestrus by estrogen injection. Goldzieher (3) and Eller and Eller (4) demonstrated noticeable proliferation in atrophied skin of senile women following topical application of estrogenic ointments. Application of estradiol ointment to the skin of senile and infantile rats by Kun (5) resulted in cellular proliferation of the epidermis; and Selye (6) reported a marked increase in keratinized epidermis of genetically hairless mice following topical application of estradiol in oil. Conversely, Hooker and Pfeiffer (7) noted that prolonged treatment with a high dosage of estradiol benzoate (83 fig. twice a week for 10 months) resulted in marked thinning of the epidermis of rats. H. F. Bullough (8) suggested that this difference in effect of estrogen might be a result of dosage and duration of treatment. The present experiments support this suggestion and demonstrate that estrogen in small, physiological doses is a stimulant to cellular proliferation of the epidermis, whereas high doses are inhibitory and cause thinning of the epidermis. They extend a large project dealing with experimental epidermal carcinogenesis in mice which has been under way for twelve years and of which the results have been summarized by Cowdry (9). In particular they are related to the part of this project concerned with the influence of estradiol benzoate on epidermal carcinogenesis as described by Paletta and Max (10).

Die konservative Behandlung entzündlicher Genitalerkrankungen der Frau.

Döderlein, who is associated with the gynecologic clinic of the Berlin Charité, presents a monographic review of genital inflammations. The monograph is divided into three parts. In the first part the author discusses etiology, pathogenesis and diagnosis of genital infections. In the diagnosis of gonorrhea he mentions the vulnerability of the vagina of the child, of the pregnant woman and of the senile woman. The sedimentation test (Linzemeier technic) is stressed as an important procedure in the diagnosis and prognosis of inflammatory adnexal disease. The second part of the book deals with the management of the nonspecific genital inflammations; there is a scholarly differential diagnosis of pruritus vulvae, including detailed description of such unusual conditions as ulcus vulvae acutum and ulcus vulvae chronicum (esthiomene). The author gives only passing mention to trichomonas vaginitis and maintains the opinion that the parasite is nonpathogenic. However, in the presence of trichomonas, he advises