<abstract><p>This paper is mainly concerned with the initial boundary value problems of semilinear wave equations with damping term and mass term as well as Neumann boundary conditions on exterior domain in three dimensions. Blow-up and upper bound lifespan estimates of solutions to the problem with damping term and mass term are derived by applying test function technique and iterative method, where nonlinear terms are power nonlinearity $ |u|^p $, derivative nonlinearity $ |u_{t}|^p $, combined nonlinearities $ |u_t|^p+|u|^q $, respectively. Moreover, upper bound lifespan estimate of solution to the problem with scale invariant damping term, non-negative mass term and combined nonlinearities $ |u_t|^p+|u|^q $ is obtained. The proofs are based on the test function method and iterative approach. The main new contribution is that upper bound lifespan estimates of solutions are associated with the Strauss exponent and Glassey exponent. In addition, the variation trend of wave is achieved by taking advantage of numerical simulation.</p></abstract>