Self-reported Well-being Research Articles

Psychological Health Among Older Adults During and After Quarantine: A Multi-Method Study.

Depression among older adults is a growing problem. With aging being a risk factor for COVID-19 infection, depression in this population may have been exacerbated. This study aimed to describe experiences and changes in depressive symptoms and well-being of older adults during and after the COVID-19 first wave in Spain. The study used a multi-method design. Participants self-reported depressive symptoms (Geriatric Depression Scale) and well-being (Cantril Ladder of Life). Participants were asked about changes in depressive symptoms or well-being during quarantine. If a change was perceived, they were asked to describe the change. In addition, the Patient Global Impression of Change scale was used. Both quantitative and qualitative analyses were performed on the data. 111 participants (mean age: 71±5 years; 76% women) completed the study. Sixty-three percent reported mild and 2% reported major depressive symptoms. Nearly half (47.7%) reported changes in depressive symptoms during the lockdown. While 37% reported feeling better during the lockdown, about 11% reported depressive symptoms were worse now compared with during the lockdown. 60% reported worsening well-being during the quarantining period. The qualitative analysis revealed 2 main themes: (1) psychological discomfort (mood deflection, fear/worries, and boredom/inactivity) and (2) social issues (inability to go out, missing family members and others). Worsening depressive symptoms and lowering of well-being were noticed in this sample of older adults during and post-COVID lockdowns. Evaluation of mental health in the primary care setting and providing referrals for mental health services is essential for older adults who experienced COVID-19-related lockdowns.

Creative and Happy Individuals Concerned about Climate Change: Evidence Based on the 10th Round of the European Social Survey in 22 Countries

Previous studies, to some extent, link creativity, well-being, and environmental concerns. Therefore, the purpose of this study was to examine the associations between self-reported creativity, psychological well-being, and climate change concerns. This study was based on data derived from the European Social Survey’s 10th round and applied several items from sections H, B, and C. The findings revealed that creativity was positively linked to climate change concerns and psychological well-being, while psychological well-being was, to some extent, negatively related to climate change concerns. The SEM model demonstrated an acceptable fit, χ2 = 1627.862; Df = 7; CFI = 0.959; TLI = 0.876; NFI = 0.958; RMSEA = 0.078 [0.075–0.082]. Additionally, the findings indicated that more creative and happy individuals were also more concerned about climate change; they were more prone to believe that climate change is caused by human activity, they felt a higher personal responsibility to reduce climate change, and they were significantly more worried about climate change. This implies that as creative and happy individuals have a heightened sense of responsibility for climate change, these individuals may indeed play a key role in promoting climate change awareness and actions, including communication on sustainability, sustainability-related projects, and other activities; thus, tailored campaigns could be developed within the frames of citizen science. The findings also suggest implications for policy development: policymakers could consider the perspectives of creative and happy individuals when crafting climate policies, potentially leading to more effective and widely accepted solutions.

Cognitive and affective control for adolescents in care versus their peers: implications for mental health

BackgroundMany adolescents who have been removed from the care of their biological parent(s) and placed in State or Local Authority care have experienced significant adversity, including high rates of maltreatment and other trauma(s). As a group, these young people experience far higher rates of mental health difficulties compared to their peers. While their mental health outcomes are well-documented, little is known about mechanisms that may drive this. One potential mechanism, linked to both trauma and adversity exposure and mental health, is affective control (the application of cognitive control in affective contexts).MethodsWe compared cognitive and affective control in 71 adolescents (65% girls) in care aged 11–18 (M = 14.82, SD = 2.10) and 71 age and gender-matched peers aged 11–19 years (M = 14.75, SD = 1.95). We measured cognitive and affective control using standard experimental tasks, and for those in care, we also examined associations with self-reported emotion regulation, mental health, and school well-being.ResultsAfter controlling for IQ, there was a significant group difference in affective control performance, with those in care on average performing worse across all tasks. However, further analyses showed this was driven by deficits in overall cognitive control ability, and was not specific to, or worsened by, affective stimuli. Further, we found no evidence that either cognitive or affective control was associated with emotion regulation abilities or the mental health and well-being of young people in care.ConclusionsResults suggest that cognitive and affective control may not underlie mental health for young people in care, though limitations should be considered. We discuss implications for theory and intervention development, and avenues for further research.Trial registration: https://doi.org/10.17605/OSF.IO/QJVDA

34 Association Between Subjective Cognitive Decline and Mental Wellbeing in Normal Cognition and MCI Older Adults

Objective:Subjective cognitive decline (SCD, i.e., perceived cognitive decline without neuropsychological deficits) is associated with Alzheimer’s disease pathology and increased risk for cognitive impairment but is heterogenous in etiology and has been linked to other factors including personality and depression. Mental wellbeing (i.e., the perception and functioning of social, emotional, and health-related aspects of one’s life) has been associated with subjective memory complaints, but its relationship with other subjective cognitive domains is poorly understood. Further characterizing the relationship between mental wellbeing and SCD could refine understanding of SCD and inform development of interventions that prevent progression to objective cognitive decline. This study aimed to describe the relationship between mental wellbeing and subjective decline in multiple cognitive domains and examine whether this relationship differs between older adults with normal cognition and those with mild cognitive impairment (MCI).Participants and Methods:Community-dwelling older adults (normal: n = 58, Mage = 73.7±5.6; MCI: n = 43, Mage = 75.9±6.1) completed the Everyday Cognition scale, a validated self-report measure of SCD, and the RAND-36 Health Survey, a validated self-report measure of health-related quality of life which includes a mental wellbeing subscale. Spearman’s rank correlations were conducted between self-reported mental wellbeing and each self-reported cognitive domain (i.e., memory, language, visuospatial, and executive function) for the Normal Cognition and MCI groups.Results:Worse mental wellbeing was associated with worse subjective language and executive function in the normal group, rs(56) = -.42, p =.001; rs(56) = -.37, p =.005, but not for the MCI group, rs(41) = -.23, p =.15; rs(41) = -.12, p =.46. Worse mental wellbeing was associated with worse subjective visuospatial function in the MCI group, rs(41) = -.39, p =.009, but not in the normal group, rs(56) = -.11, p =.39. For both groups, worse mental wellbeing was associated with worse subjective memory, rs(56) = -.45, p < .001; rs(41) = -.37, p =.02. While this correlation was greater in the normal group, the difference was not significant (z = 0.38, p =.71).Conclusions:These results suggest that perceptions of mental wellbeing are related to perceptions of cognitive decline in multiple domains, and that the specific domains involved differ between normal and MCI groups. The differential associations may mean perception of specific cognitive domains more strongly affect mental wellbeing, or mental wellbeing more acutely influences perception of those domains. The overall observed relationship between SCD and mental wellbeing may have several explanations: the impact of broader health perceptions may extend to cognitive perception, behavioral changes associated with poor wellbeing may reduce subjective cognitive function, or worse subjective cognitive function may lead to negative experiences of wellbeing. Future longitudinal investigation could inform causal inferences. The more limited associations between mental wellbeing and SCD among MCI individuals may point to the role of decreased self-awareness (due to cognitive impairment) precluding detection of subtle changes in cognition or wellbeing. This study highlights the importance of better understanding mental wellbeing in experiences of SCD in both normal and MCI older adults to improve cognitive and mental health outcomes.

Adolescent Young Carers Who Provide Help and Support to Friends.

Prior studies emphasize the value of friends' support for children/adolescents who have a disability or suffer from mental ill-health or a long-term illness. However, few studies have explored how a caring role affects those young friend carers themselves. This paper addresses a gap in the research by focusing on this hitherto neglected group of young carers to explore the impact of providing care to friends. An online survey was employed for a cross-national study conducted in 2018-2019 in Sweden, Italy, Slovenia, the Netherlands, Switzerland, and the United Kingdom to examine the incidence of adolescent young friend carers, the extent of care they provide, and their self-reported health, well-being, and school situation. The survey was completed by 7146 adolescents, aged 15-17, and 1121 of them provided care to a friend with a health-related condition, most frequently mental ill-health. They carried out high levels of caring activities, and a quarter of them also provided care to a family member. They experienced both positive and negative aspects of caring. Nevertheless, in comparison with adolescents who provided care to family members, they reported more health problems, with a dominance of mental ill-health, and they received lower levels of support. Since adolescent friends play a valuable role for young people with health-related conditions, especially mental ill-health, it is important to find ways of optimizing their caring experiences in order that those adolescents who choose to care for a friend can do so without it having a negative impact on their own mental health, well-being, and life situation.

49 Health Literacy and Well-Being in Older Adults

Objective:Although health problems are often a natural consequence of aging, many older adults struggle to manage their health care problems. Health literacy refers to the ability to access, process, and use health information to make appropriate decisions to promote good overall health. Low levels of health literacy are associated with a host of negative outcomes such as less efficient use of healthcare services, higher healthcare costs, increased mortality, and poorer self-rated health. In those with medical conditions (e.g., diabetes), lower health literacy is linked with higher levels of depression. It is important to investigate whether mental health is linked to health literacy as understanding these links has the potential to identify those at risk for negative outcomes and thus implement protective strategies. Therefore, the current study sought to determine the extent to which various mental health constructs such as happiness, well-being, anxiety and depression are related to health literacy in a community-based sample of cognitively healthy individuals. We hypothesized that higher levels of health literacy would be associated with higher self-reported well-being, happiness, and lower anxiety and depression.Participants and Methods:Design - Cross-sectional, prospective study. Setting - Community-based. 93 individuals were included with mean age=59.02 years (SD=15.12) and mean education=15.70 (SD=2.39). 60% were women, the majority were White (55%) while 38% were Black and 7% belonged to other races; 90% were non-Hispanic.Measures:Health Literacy - Health literacy was measured by an 8-item instrument in the Rush Memory and Aging Project that examined the participant’s understanding of health care, treatment, and related behaviors. Happiness - Happiness was measured by 5 items from the Satisfaction with Life Scale using a 7-point scale (1 = strongly agree; 7 = strongly disagree). Higher scores indicated lower levels of happiness. Well-being - Well-being was measured with an 18-item instrument from the Rush Memory and Aging project, with higher scores indicating better well-being. Statistics: Bivariate correlations between age, education, and mental health measures and health literacy were examined.Results:Higher level of health literacy was significantly associated with age (r = .282 p = .009) and education (r = .228 p = .039). Contrary to our hypothesis, health literacy was not significantly associated with happiness (r = .002 p = .987), well-being (r = .037 p = .742), depression (r = .005 p = .962) or anxiety (r = -.064 p = .568). Even after controlling for age and education, these associations remained significant.Conclusions:Higher level of healthy literacy was associated with older age and higher level of education. However, no significant association was found between health literacy and mental health measures of happiness, well-being, depression, and anxiety in cognitively healthy individuals, even after controlling for demographics. The lack of such associations in this study was unexpected and suggests that other factors such as the presence of health conditions (e.g., diabetes, cancer) might critically contribute to such associations. Future studies should examine these associations in a larger context to better understand how to promote healthy self-care behaviors.

Mediating effect of sleep in the association between social media use and mental health among French adolescents during the COVID-19 sanitary crisis

Objective/BackgroundSocial media use could have deleterious effects on mental health through short sleep duration and poor sleep quality among adolescents. This study aimed to investigate the mediating role of both sleep duration and sleep quality in the association between social media use and mental health among adolescents. Patients/methodsWe used cross-sectional data collected from adolescents in the EXIST pilot project conducted during COVID-19 pandemic. Adolescents self-reported wellbeing (WEMWBS), anxiety and depression (HADS) as mental health outcomes. We used ad-hoc questionnaires to assess social media use during weekdays and weekend days, and sleep duration and quality. Mediation analyses were carried out following Baron and Kenny's method, using adjusted linear regression models. ResultsA total of 340 adolescents (13.5 ± 0.6 years, 45.3 % girls) were included. Greater social media use, poorer sleep quality, and shorter sleep duration were associated with poorer mental health. Greater social media use was associated with poorer sleep quality only during the weekend days. The total effect of social media use during weekend days on anxiety (β = 2.54; 95%CI [-1.59; 6.68]) was significantly conveyed through sleep quality (β = 1.22; 95%CI [0.17; 2.62]; mediated proportion = 48.0 %) and duration (mediated proportion = 46.8 %). Mediated proportions ranged from 12.5 % to 20.6 % for wellbeing and depression. Mediating effects were not evident during weekdays. ConclusionsSleep duration and quality mediated the association between social media use and mental health among adolescents during weekend days but not weekdays. Our findings highlight the importance of promoting healthy social media habits, especially during periods of increased reliance on digital platforms, such as COVID-19 pandemic.

Two roads diverge in cyberspace: dual but opposing social media pathways affecting teens’ well-being

Purpose Many believe that any social media harms kids because of frequent use. This study aims to examine these assumptions. It proposes and tests a model that considers two alternative pathways – one negative and one positive – through which social media affects teens’ self-reported subjective well-being. Design/methodology/approach This research used Preacher and Hayes process modeling to conduct path analysis on data collected on 585 teenagers from across the USA. Findings Results showed that along a negative pathway, frequent social media use leads to greater risky social media engagement that ultimately diminishes adolescent’s sense of well-being. Also, and perhaps simultaneously, frequent social media use leads to socially-connected social media use that enhances adolescent’s sense of well-being. Practical implications The research recommends ways parents, policymakers and platforms can encourage teens to use social media to connect with friends while guiding them away from pathways exposing them to risky behaviors. Originality/value Findings show more social media use is not necessarily harmful, but more of some types is bad, while more of others is good.

A - 29 Understanding the Role of Caregiver Self-Efficacy in Dementia Healthcare: Findings from the Care Ecosystem Program.

Identify changes in healthcare utilization (HCU) and admission risk scores (ARS) by caregiver self-efficacy levels (CGSE) in persons with dementia (PWD). 179 community-dwelling dyads (PWD-CG) with at least 1 emergency or hospital admission 12-months prior to enrollment in the Care Ecosystem (dementia care-management program), provided data at baseline, 6, and 12-months. Analyzed data included caregiver self-reported HCU, dementia ratings (QDRS, NPI), wellbeing (ZBI-12, NPI-Distress, PHQ9), and CGSE scales. HCU confirmation and ARS were extracted from electronic medical records. Repeated measures ANOVA and paired sample t-tests compared ARS and HCU across time points by baseline CGSE. On average, PWD and caregivers were 80 (SD:8) and 64years-old (SD:11); predominantly female (PWD:63%, CG: 77%) and white (62%), with 12+ years of education (PWD: 84%, CG: 98%). Self-efficacy improved over time [F(1.92, 281.74 = 11.56, p < 0.001, ηp2 = 0.13]; post-hoc Bonferroni indicated increases from 19.37 to 20.62 at 6-months (95% CI, 0.59-1.92) and 20.56 at 12-months (95% CI, 0.41-1.98). Reductions in ARS [t(178) = 2.63, p = 0.009, MD = 3.34, d = 0.2] and HCU [t(177) = 5.37, p < 0.001, MD = 0.85, d = 0.4] were observed at program completion. The high-CGSE group demonstrated significant ARS [t(98) = 3.43, p = 0.001, d = 0.4] and HCU reductions [t(98) = 3.65, p < 0.001, d = 0.4]. HCU also decreased for the moderate-CGSE cohort [t(43) = 4.17, p < 0.001, d = 0.6]. Groups with higher CGSE experienced greater reductions in ARS and HCU compared to lower CGSE. Self-reported measures and CGSE-group sample sizes may limit our findings.

An evaluation of self-reported material well-being using latent Markov models with covariates.

A household's financial satisfaction is one of the most significant factors driving subjective well-being. However, Poland ranks close to the lowest position, 22nd out of the 28 EU members, in self-reported financial status. The paper investigates the problem of determining patterns of Polish households' behaviour and shows the evolution of the subjective assessment of financial situation based on the eight waves of the Polish Household panel data. The analysis is carried out on the basis of latent Markov (LM) models, which allow for socio-economic features affecting the parameters of the latent process. We compare different types of LM models considering: (1) different numbers of latent structures; (2) different types of the latent process constraints; (3) socio-economic background characteristics; and (4) survey weights (being excluded in most of the empirical analyses). The final model identifies three latent states, specifies common initial and transition probabilities over a 15-year period and, as a result, enables us to better characterise the families likely to change their position, especially families reporting worsening in their financial situation. To show the main direction of self-reporting financial condition, we present the predicted path for respondents characterised by the selected socio-economic features, relying on algorithm maximising posterior probabilities of the selected LM model.

Ethical Dilemmas, Rewards, and Lessons for the Future: Conducting Participatory Photographic Research With Asylum Seekers

This paper draws on my experience of organising a photovoice project with asylum seekers to outline the ethical dilemmas and rewards of planning and facilitating a participatory, creative research project with a hard-to-reach, potentially vulnerable population. It offers lessons learnt and useful insights for others considering a similar approach to data collection. The photo project was utilised to explore the impact of involvement with community-based social protection on the self-reported wellbeing of asylum seekers in the United Kingdom. It was also designed to test the efficacy of the photovoice research methodology to produce simple, impactful findings useful for researcher, research participant and policymaker, empowering those who have often had little voice in community development to inform policy discussions. The paper is written from the author’s perspective, adopting a layered approach that utilises fieldnotes, quotes from project participants, and exhibition attendee feedback to provide a rounded description of the project. It pays particular attention to ethical dilemmas concerning project access, recruitment and communication and the complexity of juggling academic ethical rigour with a community-led approach across cultural and linguistic borders. It highlights how power dynamics can be experienced in the research environment entangled with issues of co-researcher dignity, ownership, and vulnerability. It also details the positive outcomes of the photovoice project in relation to collaborative knowledge creation, empathetic understanding, and advocacy opportunities. The author concludes by offering a summary of the key lessons learnt through the project and their implications for future research.

Slower respiration rate is associated with higher self-reported well-being after wellness training

Mind–body interventions such as mindfulness-based stress reduction (MBSR) may improve well-being by increasing awareness and regulation of physiological and cognitive states. However, it is unclear how practice may alter long-term, baseline physiological processes, and whether these changes reflect improved well-being. Using respiration rate (RR), which can be sensitive to effects of meditation, and 3 aspects of self-reported well-being (psychological well-being [PWB], distress, and medical symptoms), we tested pre-registered hypotheses that: (1) Lower baseline RR (in a resting, non-meditative state) would be a physiological marker associated with well-being, (2) MBSR would decrease RR, and (3) Training-related decreases in RR would be associated with improved well-being. We recruited 245 adults (age range = 18–65, M = 42.4): experienced meditators (n = 42), and meditation-naïve participants randomized to MBSR (n = 72), active control (n = 41), or waitlist control (n = 66). Data were collected at pre-randomization, post-intervention (or waiting), and long-term follow-up. Lower baseline RR was associated with lower psychological distress among long-term meditators (p* = 0.03, b = 0.02, 95% CI [0.01, 0.03]), though not in non-meditators prior to training. MBSR decreased RR compared to waitlist (p = 0.02, Cohen’s d = − 0.41, 95% CI [− 0.78, − 0.06]), but not the active control. Decreased RR related to decreased medical symptoms, across all participants (p* = 0.02, b = 0.57, 95% CI [0.15, 0.98]). Post-training, lower RR was associated with higher PWB across training groups compared to waitlist (p* = 0.01, b = 0.06, 95% CI [0.02, 0.10]), though there were no significant differences in change in PWB between groups. This physiological marker may indicate higher physical and/or psychological well-being in those who engage in wellness practices.

The Associations Between Wellbeing and Injury Differ by Time Loss in Collegiate Athletes.

Self-reported wellbeing measures such as mood and soreness have been identified as predictors of injury risk. However, most research has focused on investigating time-loss injuries even though nontime-loss injuries are more prevalent. Impairments in sleep and subjective wellbeing would be associated with increased injury for both time-loss and nontime-loss injuries. Prospective longitudinal study. Level 3. During 2022, 127 athletes completed a daily survey that inquired about training load and sleep from the previous day along with mood, stress, and soreness on the current day. Incidence of injury was also monitored using documentation provided by athletes' respective athletic trainers. Mixed effect models were used to analyze the relationship between wellbeing and sleep measures with injury. Self-reported wellbeing, based most closely on soreness the day of injury, by National Collegiate Athletic Association Division 1 collegiate athletes was predictive of time-loss injuries, whereas no significant relationship was identified for nontime-loss injuries. Specifically, 1 unit increase in soreness was associated with a 39% increase in odds of sustaining a time-loss injury. This study found that subjective wellbeing and sleep have a different relationship with injury dependent upon whether the resulting injury leads to time loss. Self-reported wellbeing appears to be a relevant predictor of injury among collegiate athletes for time-loss injuries.

Engaging parents to reduce youth violence: evidence from a youth justice board pathfinder programme

AbstractThe Youth Justice Board’s 2019–2022 strategic plan set youth violence as a priority. As part of this, a ‘pathfinder’ approach was launched to assist local authorities and their partners to devise, develop, and disseminate whole systems approaches to serious youth violence (Youth Justice Board in Pathfinder—YJB, https://yjresourcehub.uk/working-with-partners/item/651-pathfinder-yjb.html Youth Justice Board Annual Report and Accounts 2020/21, 2020). In partnership with a regional Violence Reduction Unit, seven local Youth Offending Teams worked together with a programme that facilitated peer support networks for parents of children known to the youth justice system. The programme presented a challenge to a view in statutory youth justice of parents as part of the problem (Burney and Gelsthorpe in Howard J Crimin Justice 47(5):470–485, 2008). The aim of the programme was to engage parents of young people involved in the youth justice system, facilitating peer to peer support through a blend of online and face-to-face meetings. Taking a mixed-method approach, the research sought to investigate the impact of the programme on participants’ well-being and perceived competence with parenting. A secondary aim was to explore experiences of the self-care and peer support activities offered by the programme. The quantitative findings showed statistically significant increases in parents’ self-reported well-being and perceived competence with parenting during engagement with the programme. Effect sizes reached the minimum important difference for all of the quantitative measures, with a large effect for well-being. The qualitative findings highlighted that the self-care focus was important in engaging parents and helps distinguish the programme from statutory services. The findings are combined in the paper to produce a potential model of peer support for parents of children known to the youth justice system. Future research should investigate the impact on the children of parents who took part in this programme with a specific focus on youth violence.

'I don't chase drugs as much anymore, and I'm not dead': Client reported outcomes associated with safer opioid supply programs in Ontario, Canada.

The ongoing opioid overdose crisis, which has killed over 30,000 people in Canada since 2016, is driven by the volatility of an unregulated opioid drug supply comprised primarily of fentanyl. The Canadian government has recently funded safer opioid supply (SOS) programs, which include off-label prescriptions of pharmaceutical-grade opioids to high risk individuals with the goal of reducing overdose deaths. In 2021, we examined the implementation and adaption of four SOS programs in Ontario. These programs use a primary care model and serve communities experiencing marginalisation. We conducted semi-structured interviews with program clients. We present the results of a thematic analysis with the aim of describing clients' self-reported impact of these programs on their health and well-being. We interviewed 52 clients between June and October 2021 (mean age 47 years, 56% men, 17% self-identified Indigenous, 14% living with HIV). Our results indicate multifaceted pathways to improved self-reported health and well-being among clients including changes to drug use practices, fewer overdoses, reduced criminalised activity, improved trust and engagement in health care, and increased social stability (e.g., housing). Most clients reported that the intervention saved their life because of the reduced frequency of overdoses. Findings suggest that SOS programs improved clients' health outcomes and increase opportunities for engagement in health services. Our results provide insight into the mechanisms behind some of the emergent evidence on the impact of safer supply prescribing.

O.4.3-10 Validation and investigation of a video-assisted version of the KIDSCREEN-27 for Danish children

Abstract Background Poor well-being among children is an increasing concern worldwide. In Denmark, the decrease in well-being among children and youth has been evident in recent years making research on the promotion of well-being important. Three generic and comprehensive questionnaire-based measures of children’s well-being and quality of life of different lengths have been developed across 13 European countries (KIDSCREEN-52, KIDSCREEN-27, and KIDSCREEN-10). The questionnaires have been translated and validated in several languages – and the cross-cultural comparability and psychometric properties have been found satisfactory. However due to the required reading abilities for understanding and filling in the questionnaire the children’s self-report version has mainly been validated and used in ages 11-18 years. For this reason, parent proxy reporting is often used for children below age 11. In Denmark, the questionnaires have been translated, but no validation study has been published. Purpose To test the measurement properties and evaluate the feasibility validity and reliability of a video-assisted version of the Danish KIDSCREEN 27 child self-report on a sample of Danish children aged six to nine years. Methods An electronic version with video and speech-assisted instructions and explanations for the questionnaire was developed. The questionnaire was administered to a large sample of Danish school children aged six to nine years. Expected results and outcomes We aim to improve the measurement of self-reported well-being among children aged six to nine years by using our video and speech-assisted electronic version of the KIDSREEN-27. Preliminary findings will be presented and discussed. The study is important, as its evident that we need a better understanding of the prerequisites, causes, pathways, and indicators of children’s well-being.

Child and youth mental health and wellbeing before and after returning to in-person learning in secondary schools in the context of COVID-19.

As children reintegrate with in-person classroom learning after COVID-19, health and education institutions should remain mindful of students' mental health. There is a paucity of data on changes in students' mental health before, during and after their return to in-person classroom learning. We collected and analyzed data on self-reported wellbeing, general mental health, perceived stress, and help-seeking attitudes from grade 7-12 students in a Catholic school division in Canada (n = 258 at baseline; n = 132 at follow-up). Outcomes were compared according to demographic differences such as gender, grade level, experience accessing mental health services, and presence of support staff between baseline and follow-up. Effects of time points and each demographic variable on each outcome and on the prediction of students' mental health were also analyzed. No significant differences were apparent for outcomes between baseline and follow-up. However, specific subgroups: junior high students, male students, students who had not accessed mental health services, and students who had access to support-staff had better outcomes than their counterparts. From baseline to follow-up, male students reported mental health decline [Mean = 11.79, SD = 6.14; Mean = 16.29, SD = 7.47, F(1, 333) = 8.36, p < 0.01]; students who had not accessed mental health services demonstrated greater stress [Mean = 20.89, SD = 4.09; Mean = 22.28, SD = 2.24, F(1, 352) = 6.20, p < 0.05]; students who did not specify a binary gender reported improved general mental health [Mean = 19.87, SD = 5.89; Mean = 13.00, SD = 7.40, F(1, 333) = 8.70, p < 0.01], and students who did not have access to support-staff improved help-seeking attitudes [Mean = 22.32, SD = 4.62; Mean = 24.76, SD = 4.81; F(1, 346) = 5.80, p < 0.05]. At each time point, students indicated parents, guardians, and close friends as their most-preferred help-seeking sources. High stress predicted lower wellbeing at baseline, but higher wellbeing at follow-up. Students presented stable mental health. Subgroups with decreased mental health may benefit from extra mental health support through building capacity among teachers and health care professionals to support students following public health emergencies.

91 Patient Self-Reported Overall Well-Being Correlates with Concurrent Cancer-Related Symptoms?

91 Patient Self-Reported Overall Well-Being Correlates with Concurrent Cancer-Related Symptoms?

Effects of donation frequency on U.S. source plasma donor health.

Plasma-derived medicinal products (PDMPs) are essential, life-saving medicines manufactured from plasma donated by healthy human volunteers. PDMPs are used to treat a range of rare, serious, and chronic conditions, often genetic in origin. Approximately 70% of the Source Plasma (SP) used for PDMP manufacturing comes from United States (US). The hypothesis of the study is that US donation frequency does not impair donor self-reported functional health and well-being. A total of 5608 SP donors from 14 US SP centers were enrolled in a cross-sectional study to assess self-reported health related quality of life (HRQoL) and well-being. By sex, donors were assigned to one of four groups, according to their frequency of SP donation in the 12 months before enrollment. The SF-36v2® Health Survey (SF-36v2) and a survey assessing the frequency of various health conditions that may be associated with impaired immune function over different time periods were used. There were no statistically significant differences in SF-36v2 scores between any of the donor frequency groups, compared with new donors after controlling for potential confounding and accounting for multiple comparisons among males and females. Cough, cold, occasional fatigue, and sore throat were the most reported health conditions or symptoms, but there was no clear difference among sex or frequency groups. The self-reported data in this study support the hypothesis that compensated donations at US FDA permitted frequencies and volumes are consistent with maintaining donor health. Compared with the general population, SP donors have comparable or better health than the general population.

Why do US source plasma donors stop donating?

In the United States, source plasma (SP) donors can donate up to 104 times per year. Considering the global need for SP and plasma-derived medicinal products, it is critical to maintain the health of frequent donors. This study explores SP donors' self-reported reasons for a lapse in donating. There were 5608 SP donors from 14 SP centers who enrolled in a longitudinal cohort study to assess self-reported functional health and well-being. Donors were assigned to one of four groups, according to the frequency of SP donation in the 12 months before enrollment. One thousand four hundred forty-eight SP donors who lapsed in donating during 6 months or greater during the study follow-up were asked to complete a survey. There were 545 lapsed SP donors who returned surveys (37.6%); 63% were female. Most responses given for stopping SP donation were categorized as convenience reasons (69.1%). Self-reported health concerns, including being deferred multiple times, which were categorized as possibly related or unable to determine a relationship to plasmapheresis, represented 45.5% of the responses. Primary reasons US SP donors report for a lapse in donation were categorized as convenience (e.g., schedule conflicts/lack of time). Donor responses categorized as health concerns which have a possible or uncertain relationship to plasmapheresis were less frequent but present in all frequency groups. This study adds to the body of evidence that SP donors cease donating for a variety of self-reported reasons with the majority not directly related to a perceived negative impact on their health.