Abstract Introduction The Pittsburg Sleep Quality Index (PSQI) is widely used in different population groups to assess self-reported sleep quality over the previous month. As the Arabic language is spoken by more than 400 million people, the PSQI has been translated into Arabic for its optimal application to Arabic-speaking individuals. However, the test-retest reliability of the Arabic version of the PSQI has not been reported yet. Objective To examine the reliability and agreement of a bilingual Arabic-English version of the PSQI (AE-PSQI) among bilingual Arabic-English-speaking adolescents and young adults of the United Arab Emirates (UAE) with good or poor sleep quality. Materials and Methods We included 50 bilingual Arabic-English-speaking adolescents and young adults (mean age of 20.82 ± 2.7 years; 30/50 subjects classified as poor sleepers [PSQI > 5] at baseline) who filled put the AE-PSQI twice, 7 days apart. The internal consistency of the AE-PSQI was assessed through the Cronbach's alpha. The intraclass correlation coefficient (ICC[3,1]) was used to assess the test-retest reliability. The standard error of measurement (SEM), the smallest real difference (SRD), and the Bland-Altman plots were used to report agreement measures. Results The global score on the AE-PQSI showed an acceptable level of internal consistency with a Cronbach's alpha value of 0.65, and no floor and ceiling effects were observed. The 95% confidence intervals (95%CI: 0.63-0.87) of the ICC(3,1) revealed moderate to strong reliability estimates for overall AE-PSQI scores. The SEM and SRD were of 1.6 and 4.5 respectively, and the Bland-Altman plots revealed a moderate agreement between the baseline and retest global AE-PQSI scores. Conclusion The AE-PSQI is a reliable instrument to assess sleep quality in bilingual Arabic-English-speaking adolescents and young adults with good or poor sleep quality. Further studies on the validity and responsiveness of the AE-PSQI are warranted in individuals with and without sleep disorders.